Mechanical structure and control system for positron drug synthesis module

Abstract

The application relates to the technical field of medicine synthesis, and discloses a positive electron medicine synthesis module mechanical structure and a control system, which comprises a bottom plate, a machine shell is mounted on the upper surface of the bottom plate, an injection pump assembly is arranged on the machine shell, the injection pump assembly comprises a mounting plate, the mounting plate is fixed in the machine shell, two symmetrical fixing assemblies are arranged on the surface of the mounting plate, two symmetrical connecting frames are slidably connected to the inner wall of the mounting plate, a motion assembly is arranged on one side of the connecting frame, and the fixing assembly and the motion assembly are used for placing syringes, and the motion assembly is used for pushing the syringes to add medicine liquid. In the application, the double-positioning design of the fixing assembly and the motion assembly is adopted, steel balls and springs are matched to tightly clamp the shell and the push rod, deviation and power transmission loss are avoided, the high-precision characteristic of screw rod transmission is combined, medicine liquid quantitative addition is realized, and the precision of a synthesis process is improved.

Description

Technical Field

[0001] This invention relates to the field of drug synthesis technology, specifically to the mechanical structure and control system of a positron emission tomography (PET) drug synthesis module. Background Technology

[0002] Positron emission tomography (PET) drugs are a class of radiopharmaceuticals containing positron-emitting nuclides. They are the core reagents for PET imaging. The positrons released by the decay of the nuclide annihilate electrons in the body to generate gamma photons, which are then imaged by PET equipment to detect functional metabolism at the molecular level in the body. They are widely used in the clinical diagnosis and research of tumors, cardiovascular and cerebrovascular diseases, and nervous system diseases.

[0003] Currently, the syringe fixing and driving structure design of traditional synthesis equipment is rudimentary, which is prone to problems such as clamping deviation and power transmission loss, resulting in insufficient drug dispensing accuracy and affecting the accuracy of nuclear drug synthesis ratio. To address this, we propose a mechanical structure and control system for a positron emission tomography (PET) drug synthesis module. Summary of the Invention

[0004] To address the shortcomings of existing technologies, this invention provides a mechanical structure and control system for a positron emission tomography (PET) drug synthesis module. This solves the problems of rudimentary syringe fixing and driving structure design in existing synthesis equipment, which easily leads to clamping misalignment and power transmission loss, resulting in insufficient drug dispensing accuracy and affecting the accuracy of radiopharmaceutical synthesis ratios.

[0005] To achieve the above objectives, the present invention provides the following technical solution: a positron emission tomography (PET) drug synthesis module mechanical structure, including a base plate, a housing mounted on the upper surface of the base plate, an injection pump assembly mounted on the housing, the injection pump assembly including a mounting plate fixed inside the housing, two symmetrically arranged fixing components on the surface of the mounting plate, two symmetrically arranged connecting brackets slidably connected to the inner wall of the mounting plate, a moving component on one side of each connecting bracket, syringes placed in the fixing and moving components, the moving component pushing the syringes to dispense the drug solution, a multi-bottle rack fixedly connected to the upper surface of the housing, and a protective component on the upper surface of the housing, the protective component including a base mounted on the upper surface of the housing. A support rod is fixedly connected to the upper surface of the base, and a stop is fixedly connected to one side of the support rod. A slide is slidably connected to the support rod, and a limiting sleeve is installed at one end of the slide. The upper end of the syringe is located on the movement trajectory of the limiting sleeve, and the upper end of the syringe is adapted to the inside of the limiting sleeve. A positioning seat is fixedly connected to one side of the limiting sleeve, and a swing rod is damped and rotatably connected to the inner wall of the positioning seat. A buckle is fixedly connected to one end of the swing rod, and a positioning magnet for adsorbing the slide is installed on the lower surface of the stop. Through the dual positioning design of the fixed component and the moving component, the steel ball and the spring cooperate to achieve a tight clamping between the outer shell and the push rod, avoiding deviation and power transmission loss. Combined with the high-precision characteristics of the screw drive, quantitative dispensing of the drug solution is achieved, improving the accuracy of the synthesis process.

[0006] Preferably, the fixing component includes a fixing seat and a first cover. The fixing seat is fixedly connected to one side of the mounting plate. The first cover is installed on the lower surface of the fixing seat. The outer shell of the syringe is inserted between the fixing seat and the first cover. The moving component includes a moving seat and a second cover. The moving seat is installed on one side of the connecting frame. The second cover is installed on the upper surface of the moving seat. The plunger of the syringe is inserted between the moving seat and the second cover. An injection pump body is installed on the side of the mounting plate away from the syringe. A screw is installed at the output end of the injection pump body. A moving block is threaded onto the screw. One side of the moving block slides against the surface of the mounting plate. The end of the connecting frame away from the moving seat is fixedly connected to the surface of the moving block by bolts.

[0007] Preferably, a positioning block is fixedly connected to the side of the mounting plate near the injection pump body. The upper end of the screw is rotatably connected to the lower surface of the positioning block. The syringe is dually positioned by the fixed component and the moving component. The fixed seat and the first seat cover form a receiving cavity. The first set screw compresses the first spring to push the first ball bearing platform, so that the first steel ball tightly abuts against the syringe shell, ensuring that the shell is stable and does not shift. The moving seat and the second seat cover clamp the syringe plunger. The second spring drives the second steel ball to press the plunger through the second ball bearing platform, ensuring accurate power transmission. After the injection pump body is started, the drive screw rotates, causing the threaded moving block to slide along the surface of the mounting plate. The moving block pulls the moving component to move through the connecting frame, thereby pushing the syringe plunger to realize the quantitative injection of the liquid medicine.

[0008] Preferably, the inner wall of the fixing seat is threaded with a first set screw, the inside of the fixing seat contains a first spring, the inside of the fixing seat is slidably connected with a first ball bearing platform, the first spring is located between the first set screw and the first ball bearing platform, the inside of the fixing seat contains a first steel ball, the first steel ball is located below the first ball bearing platform, and the first steel ball abuts against the outer shell of the syringe.

[0009] Preferably, the inner wall of the motion seat is threaded with a second set screw, a second spring is placed inside the motion seat, a second ball bearing platform is slidably connected inside the motion seat, the second spring is located between the second set screw and the second ball bearing platform, a second steel ball is placed inside the motion seat, the second steel ball is located below the second ball bearing platform, and the second steel ball abuts against the plunger of the syringe.

[0010] Preferably, a partition is installed inside the housing, a placement hole is opened on the upper surface of the housing, and a bracket is installed on the inner top wall of the housing. The bracket is located directly below the placement hole. The multiple bottle rack, placement hole and bracket ensure that the raw material bottles are stored in an orderly manner and connected to the pipeline.

[0011] Preferably, the upper surface of the base plate is provided with a positioning component, and three equally spaced column fixing members are installed on one side of the housing.

[0012] Preferably, the positioning component includes a shielding bracket mounted on the upper surface of the base plate. A lead shielding block is mounted on one side of the shielding bracket. The protective design of the positioning component reduces safety risks, and the dedicated installation structure of the detection equipment ensures data accuracy, meeting the special requirements of positron emission tomography (PET) drug synthesis. The multi-bottle rack on the upper surface of the housing is used to store raw material bottles, and the placement holes cooperate with the lower bracket to achieve the positioning and installation of raw material bottles and pipeline connection. In the positioning component on the base plate, the shielding bracket and the lead shielding block form a radiation protection space to avoid radiation leakage during drug synthesis. The flow meter bracket and flow meter base, and the activity meter bracket and activity meter baffle provide installation positioning for the flow monitoring equipment and activity detection equipment, respectively, to ensure accurate detection data.

[0013] Preferably, a flow meter bottom groove is fixedly connected to the upper surface of the base plate, a flow meter bracket is fixedly connected to the upper surface of the base plate, an activity meter frame is fixedly connected to the upper surface of the base plate, and an activity meter baffle is fixedly connected to the upper surface of the base plate, with the activity meter baffle sleeved on the activity meter frame.

[0014] Preferably, the control system for the mechanical structure of the positron emission tomography (PET) drug synthesis module includes a host computer, a PLC controller, a sensor group, and an execution component. The host computer is communicatively connected to the PLC controller, the sensor group is connected to the signal input terminal of the PLC controller, and the execution component is connected to the signal output terminal of the PLC controller.

[0015] The host computer provides a visual operation interface, which supports free selection of synthesis steps, equipment selection, and setting of parameters such as flow rate, temperature, syringe speed and position. The equipment status is distinguished by color, and steps can be changed and locked in real time, adapting to multiple types of radiopharmaceutical synthesis processes.

[0016] The PLC controller performs logical judgments and closed-loop control, receives the step selection results from the host computer and determines the conditions. Once the conditions are met, it outputs a drive signal. At the same time, it collects real-time data and compares it with the set values, and automatically adjusts the operating parameters of the execution components. The equipment adopts a host computer PLC control architecture. The operator can freely select synthesis steps, start the equipment and set parameters through the host computer interface without relying on PLC engineers to modify the program on-site. The interface distinguishes the equipment status by color and supports real-time changes and confirmation lock of steps, adapting to the synthesis process requirements of different radiopharmaceuticals.

[0017] The sensor array collects flow rate, temperature, and syringe stroke data in real time, providing a precise basis for parameter control. For flow rate and temperature parameters, the operator inputs set values ​​in the corresponding steps. The control system collects operating data in real time through sensors, compares it with the set values, and automatically adjusts the pump speed or heater power to ensure stable process parameters. The syringe control, by setting the origin position, target position, and moving speed, combined with the high-precision characteristics of the screw drive, achieves precise stroke control of the liquid drawing and pushing actions to meet different injection volume requirements.

[0018] The execution components drive the pump, regulate temperature, inject the liquid into the syringe, and open and close the valves. They work in conjunction with the screw drive structure to ensure precise operation. After receiving the step selection results from the host computer, the control system performs logical judgments. When the intermediate value conditions set for both the large and small steps are met, it outputs the device drive signal to achieve orderly linkage of components such as pumps, valves, and syringes. At the same time, the system integrates a start-stop self-test function to detect the status of each mechanical structure, sensor, and pipeline connection before synthesis. If any abnormality occurs, an alarm is triggered by an indicator light to ensure the safety and reliability of the synthesis process.

[0019] The PLC controller integrates start / stop self-test functions, detecting the status of mechanical connections, sensors, and pipelines before synthesis. In case of abnormalities, it will alarm via indicator lights. The host computer, in conjunction with the PLC control architecture, supports the free configuration of synthesis steps, equipment, and parameters without requiring engineers to modify the program on-site. Steps can be changed and locked in real time, adapting to the synthesis processes of different radiopharmaceuticals, greatly improving the convenience and efficiency of operation.

[0020] In summary, the technical effects and advantages of this invention are as follows:

[0021] 1. In this invention, through the dual positioning design of fixed components and moving components, the steel ball and spring work together to achieve tight clamping between the outer shell and the push rod, avoiding deviation and power transmission loss. Combined with the high precision characteristics of screw drive, quantitative injection of medicine is achieved, improving the accuracy of the synthesis process.

[0022] 2. In this invention, multiple bottle racks, placement holes, and brackets ensure orderly storage of raw material bottles and connection to pipelines. The protective design of the positioning components reduces safety risks, and the dedicated installation structure of the testing equipment ensures data accuracy, meeting the special scenario requirements of positron emission tomography (PET) drug synthesis.

[0023] 3. In this invention, the host computer, in conjunction with the PLC control architecture, supports the free configuration of synthesis steps, equipment and parameters. Engineers do not need to modify the program on-site. The steps can be changed and locked in real time, adapting to the synthesis processes of different radiopharmaceuticals, greatly improving the convenience and efficiency of operation.

[0024] 4. In this invention, the protective components facilitate the limiting operation of the syringe, preventing the syringe from becoming loose during equipment operation. At the same time, with the assistance of the swing rod and the buckle, the tubing connected to the syringe is supported, effectively preventing the tubing from bending or becoming blocked, and ensuring stable use of the equipment. Attached Figure Description

[0025] Figure 1 This is a schematic diagram of the overall structure of the positron emission tomography (PET) drug synthesis module of the present invention.

[0026] Figure 2 This is a partial structural schematic diagram of the mechanical structure of the positron-emitting drug synthesis module of the present invention;

[0027] Figure 3 In the mechanical structure of the positron drug synthesis module of this invention Figure 2 Internal structure diagram;

[0028] Figure 4 In the mechanical structure of the positron drug synthesis module of this invention Figure 2 Partial perspective structural diagram;

[0029] Figure 5 This is a schematic diagram of the injection pump assembly in the mechanical structure of the positron drug synthesis module of the present invention;

[0030] Figure 6 In the mechanical structure of the positron drug synthesis module of this invention Figure 5 A schematic diagram of the side view structure;

[0031] Figure 7 This is a partial cross-sectional view of the fixing component in the mechanical structure of the positron drug synthesis module of the present invention;

[0032] Figure 8 This is a partial cross-sectional view of the moving components in the mechanical structure of the positron drug synthesis module of the present invention.

[0033] Figure 9 This is a schematic diagram of the positioning component in the mechanical structure of the positron emission tomography (PET) drug synthesis module of the present invention;

[0034] Figure 10 This is a schematic diagram of the protective component in the mechanical structure of the positron emission tomography (PET) drug synthesis module of the present invention;

[0035] Figure 11 This is a system schematic diagram of the control system of the mechanical structure of the positron emission tomography (PET) drug synthesis module of the present invention;

[0036] Figure 12 This is a logic diagram of the control system for the mechanical structure of the positron emission tomography (PET) drug synthesis module of the present invention;

[0037] Figure 13 This is a simplified logic diagram of the control system of the mechanical structure of the positron drug synthesis module of the present invention.

[0038] In the diagram: 1. Base plate; 2. Housing; 3. Multi-bottle rack; 4. Placement hole; 5. Injection pump assembly; 51. Mounting plate; 52. Syringe; 53. Fixing assembly; 531. Fixing base; 532. First base cover; 533. First set screw; 534. First spring; 535. First ball bearing platform; 536. First steel ball; 54. Motion assembly; 541. Motion base; 542. Second base cover; 543. Second set screw; 544. Second spring; 545. Second ball bearing platform; 546. Second steel ball; 55. Injection pump 56. Body; 57. Screw; 58. Connecting frame; 59. Moving block; 6. Positioning block; 70. Column fixing component; 71. Positioning assembly; 72. Shielding bracket; 73. Activity meter frame; 74. Activity meter baffle; 75. Flow meter bottom groove; 76. Flow meter bracket; 77. Lead shielding frame block; 8. Partition plate; 9. Bracket; 10. Protective assembly; 101. Base; 102. Support rod; 103. Stop block; 104. Positioning magnet; 105. Slide seat; 106. Limiting sleeve; 107. Positioning seat; 108. Swing rod; 109. Buckle. Detailed Implementation

[0039] The technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.

[0040] refer to Figures 1-13The mechanical structure of the positron emission tomography (PET) drug synthesis module shown includes a base plate 1, a housing 2 mounted on the upper surface of the base plate 1, an injection pump assembly 5 mounted on the housing 2, the injection pump assembly 5 including a mounting plate 51 fixed inside the housing 2, two symmetrically arranged fixing components 53 on the surface of the mounting plate 51, two symmetrically arranged connecting brackets 57 slidably connected to the inner wall of the mounting plate 51, a motion component 54 on one side of the connecting brackets 57, a syringe 52 placed in the fixing components 53 and the motion component 54, the motion component 54 being used to push the syringe 52 to inject the drug solution, a multi-bottle rack 3 fixedly connected to the upper surface of the housing 2, a protective assembly 10 on the upper surface of the housing 2, the protective assembly 10 including a base 101 mounted on the upper surface of the housing 2, a support rod 102 fixedly connected to the upper surface of the base 101, a stop 103 fixedly connected to one side of the support rod 102, and a slide block 105 slidably connected to the support rod 102. A limiting sleeve 106 is installed at one end of the slide 105. The upper end of the syringe 52 is located on the movement trajectory of the limiting sleeve 106. The upper end of the syringe 52 is adapted to the inside of the limiting sleeve 106. When the limiting sleeve 106 is fitted on the syringe 52, it limits the syringe 52 to ensure stable use of the syringe 52. A positioning seat 107 is fixedly connected to one side of the limiting sleeve 106. A swing rod 108 is damped and rotatably connected to the inner wall of the positioning seat 107. A buckle 109 is fixedly connected to one end of the swing rod 108 to support the tubing connected to the syringe 52. A positioning magnet 104 for adsorbing the slide 105 is installed on the lower surface of the stop block 103. Through the dual positioning design of the fixed component 53 and the moving component 54, the steel ball and the spring cooperate to achieve tight clamping between the outer shell and the push rod, avoiding deviation and power transmission loss. Combined with the high-precision characteristics of the screw 56 transmission, quantitative injection of the drug solution is realized, improving the accuracy of the synthesis process.

[0041] The fixing component 53 includes a fixing seat 531 and a first cover 532. The fixing seat 531 is fixedly connected to one side of the mounting plate 51. The first cover 532 is installed on the lower surface of the fixing seat 531. The outer shell of the syringe 52 is inserted between the fixing seat 531 and the first cover 532. The moving component 54 includes a moving seat 541 and a second cover 542. The moving seat 541 is installed on one side of the connecting frame 57. The second cover 542 is installed on the upper surface of the moving seat 541. The plunger of the syringe 52 is inserted between the moving seat 541 and the second cover 542. The side of the mounting plate 51 away from the syringe 52 is equipped with an injection pump body 55. The output end of the injection pump body 55 is equipped with a screw 56. A moving block 58 is threaded onto the screw 56. One side of the moving block 58 slides against the surface of the mounting plate 51. The end of the connecting frame 57 away from the moving seat 541 is fixedly connected to the surface of the moving block 58 by bolts.

[0042] The mounting plate 51 is fixedly connected to a positioning block 59 on the side near the syringe pump body 55. The upper end of the screw 56 is rotatably connected to the lower surface of the positioning block 59. The syringe 52 is dually positioned by the fixing component 53 and the moving component 54. The fixing seat 531 and the first seat cover 532 form a receiving cavity. The first set screw 533 compresses the first spring 534 to push the first ball bearing platform 535, so that the first steel ball 536 tightly abuts against the syringe 52 shell, ensuring that the shell is stable and does not shift. The moving seat 541 and the second seat cover 542 clamp the syringe 52 push rod. The second spring 544 drives the second steel ball 546 to press the push rod through the second ball bearing platform 545, ensuring accurate power transmission. After the syringe pump body 55 is started, the drive screw 56 rotates, which drives the threaded moving block 58 to slide along the surface of the mounting plate 51. The moving block 58 pulls the moving component 54 to translate through the connecting frame 57, thereby pushing the syringe 52 push rod to realize the quantitative injection of liquid medicine.

[0043] The inner wall of the fixing seat 531 is threaded with a first set screw 533, a first spring 534 is placed inside the fixing seat 531, a first ball bearing platform 535 is slidably connected inside the fixing seat 531, the first spring 534 is located between the first set screw 533 and the first ball bearing platform 535, a first steel ball 536 is placed inside the fixing seat 531, the first steel ball 536 is located below the first ball bearing platform 535, and the first steel ball 536 abuts against the outer shell of the syringe 52.

[0044] The inner wall of the motion seat 541 is threaded with a second set screw 543. A second spring 544 is placed inside the motion seat 541. A second ball bearing platform 545 is slidably connected inside the motion seat 541. The second spring 544 is located between the second set screw 543 and the second ball bearing platform 545. A second steel ball 546 is placed inside the motion seat 541. The second steel ball 546 is located below the second ball bearing platform 545 and abuts against the plunger of the syringe 52.

[0045] The machine housing 2 has a partition 8 installed inside, a placement hole 4 on the upper surface of the machine housing 2, and a bracket 9 installed on the inner top wall of the machine housing 2. The bracket 9 is located directly below the placement hole 4. The multi-bottle rack 3, the placement hole 4 and the bracket 9 ensure that the raw material bottles are stored in an orderly manner and connected to the pipeline.

[0046] The upper surface of the base plate 1 is provided with a positioning component 7, and three equally spaced column fixing parts 6 are installed on one side of the housing 2.

[0047] The positioning component 7 includes a shielding bracket 71, which is installed on the upper surface of the base plate 1. A lead shielding block 76 is installed on one side of the shielding bracket 71. The protective design of the positioning component 7 reduces safety risks, and the dedicated installation structure of the detection equipment ensures data accuracy, meeting the special requirements of positron emission tomography (PET) drug synthesis. The multi-bottle rack 3 on the upper surface of the housing 2 is used to store raw material bottles. The placement hole 4 cooperates with the lower bracket 9 to realize the positioning installation of raw material bottles and pipeline connection. In the positioning component 7 on the base plate 1, the shielding bracket 71 and the lead shielding block 76 form a radiation protection space to avoid radiation leakage during drug synthesis. The flow meter bracket 75 and the flow meter bottom groove 74, and the activity meter bracket 72 and the activity meter baffle 73 provide installation positioning for the flow monitoring equipment and the activity detection equipment, respectively, to ensure the accuracy of the detection data.

[0048] Among them, a flow meter bottom groove 74 is fixedly connected to the upper surface of the base plate 1, a flow meter bracket 75 is fixedly connected to the upper surface of the base plate 1, an activity meter frame 72 is fixedly connected to the upper surface of the base plate 1, and an activity meter baffle 73 is fixedly connected to the upper surface of the base plate 1. The activity meter baffle 73 is sleeved on the activity meter frame 72.

[0049] The control system of the mechanical structure of the positron drug synthesis module includes a host computer, a PLC controller, a sensor group and an execution component. The host computer is connected to the PLC controller, the sensor group is connected to the signal input terminal of the PLC controller, and the execution component is connected to the signal output terminal of the PLC controller.

[0050] The host computer provides a visual operation interface, which supports free selection of synthesis steps, equipment selection, and setting of parameters such as flow rate, temperature, syringe speed and position. The equipment status is distinguished by color, and steps can be changed and locked in real time, adapting to multiple types of radiopharmaceutical synthesis processes.

[0051] The PLC controller performs logical judgments and closed-loop control, receives the step selection results from the host computer and determines the conditions. Once the conditions are met, it outputs a drive signal. At the same time, it collects real-time data and compares it with the set values, and automatically adjusts the operating parameters of the execution components. The equipment adopts a host computer PLC control architecture. The operator can freely select synthesis steps, start the equipment and set parameters through the host computer interface without relying on PLC engineers to modify the program on-site. The interface distinguishes the equipment status by color and supports real-time changes and confirmation lock of steps, adapting to the synthesis process requirements of different radiopharmaceuticals.

[0052] The sensor array collects flow rate, temperature, and syringe 52 stroke data in real time, providing a precise basis for parameter control. For flow rate and temperature parameters, the operator inputs set values ​​in the corresponding steps. The control system collects operating data in real time through the sensors, compares it with the set values, and automatically adjusts the pump speed or heater power to ensure stable process parameters. The syringe 52 control achieves precise stroke control of liquid extraction and dispensing actions by setting the origin position, target position, and moving speed, combined with the high-precision characteristics of the screw 56 drive, to meet different injection volume requirements.

[0053] The execution components realize pump driving, temperature control, syringe 52 liquid pumping and valve switching. Through linkage with the screw 56 transmission structure, the action is ensured to be precise. After receiving the step selection result from the host computer, the control system performs logical judgment. When the intermediate value conditions set by the large step and the small step are met at the same time, the device drive signal is output to realize the orderly linkage of components such as pump, valve, and syringe 52. At the same time, the system integrates start-stop self-test function to detect the status of each mechanical structure, sensor and pipeline connection before synthesis. When abnormality occurs, an alarm is triggered by the indicator light to ensure the safety and reliability of the synthesis process.

[0054] The PLC controller integrates start / stop self-test functions, detecting the status of mechanical connections, sensors, and pipelines before synthesis. In case of abnormalities, it will alarm via indicator lights. The host computer, in conjunction with the PLC control architecture, supports the free configuration of synthesis steps, equipment, and parameters without requiring engineers to modify the program on-site. Steps can be changed and locked in real time, adapting to the synthesis processes of different radiopharmaceuticals, greatly improving the convenience and efficiency of operation.

[0055] Working principle of the invention: The syringe 52 achieves dual positioning through the fixed component 53 and the moving component 54. The fixed seat 531 and the first seat cover 532 form a receiving cavity. The first set screw 533 compresses the first spring 534 to push the first ball bearing platform 535, so that the first steel ball 536 tightly abuts against the outer shell of the syringe 52, ensuring that the outer shell is stable and does not shift. The moving seat 541 and the second seat cover 542 clamp the syringe 52 push rod. The second spring 544 drives the second steel ball 546 to press the push rod through the second ball bearing platform 545, ensuring accurate power transmission. After the injection pump body 55 is started, the drive screw 56 rotates, which drives the threaded moving block 58 to slide along the surface of the mounting plate 51. The moving block 58 pulls the moving component 54 to translate through the connecting frame 57, thereby pushing the syringe 52 push rod to realize the quantitative injection of liquid medicine.

[0056] The multi-bottle rack 3 on the upper surface of the housing 2 is used to store raw material bottles. The placement hole 4 cooperates with the lower bracket 9 to realize the positioning and installation of raw material bottles and pipeline connection. In the positioning component 7 on the base plate 1, the shielding bracket 71 and the lead shielding block 76 form a radiation protection space to avoid radiation leakage during drug synthesis. The flow meter bracket 75 and the flow meter bottom groove 74, and the activity meter bracket 72 and the activity meter baffle 73 provide installation positioning for the flow monitoring equipment and the activity detection equipment, respectively, to ensure the accuracy of the detection data.

[0057] The equipment adopts a host computer PLC control architecture. Operators can freely select synthesis steps, start the equipment and set parameters through the host computer interface without relying on PLC engineers to modify the program on site. The interface distinguishes the equipment status by color and supports real-time changes and confirmation lock of steps, adapting to the synthesis process requirements of different radiopharmaceuticals.

[0058] For flow rate and temperature parameters, the operator inputs the set values ​​in the corresponding steps. The control system collects the operating data in real time through sensors, compares it with the set values, and automatically adjusts the pump speed or heater power to ensure the stability of process parameters. The syringe 52 control achieves precise stroke control of liquid drawing and pushing actions by setting the origin position, target position and moving speed, combined with the high precision characteristics of the screw 56 drive, to meet different injection volume requirements.

[0059] After receiving the step selection result from the host computer, the control system performs logical judgment. When the intermediate value conditions set by the major step and the minor step are met at the same time, it outputs the device drive signal to realize the orderly linkage of components such as pumps, valves, and syringes 52. At the same time, the system integrates start-stop self-test function to detect the status of each mechanical structure, sensor and pipeline connection before synthesis. If there is an abnormality, an alarm is triggered by the indicator light to ensure the safety and reliability of the synthesis process.

[0060] Finally, it should be noted that the above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. Although the present invention has been described in detail with reference to the foregoing embodiments, those skilled in the art can still modify the technical solutions described in the foregoing embodiments or make equivalent substitutions for some of the technical features. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present invention should be included within the protection scope of the present invention.

Claims

1. A mechanical structure for a positron emission tomography (PET) drug synthesis module, comprising a base plate (1), characterized in that: A housing (2) is mounted on the upper surface of the base plate (1). An injection pump assembly (5) is provided on the housing (2). The injection pump assembly (5) includes a mounting plate (51). The mounting plate (51) is fixed inside the housing (2). Two symmetrically arranged fixing components (53) are provided on the surface of the mounting plate (51). Two symmetrically arranged connecting brackets (57) are slidably connected to the inner wall of the mounting plate (51). A moving component (54) is provided on one side of the connecting bracket (57). A syringe (52) is placed in the fixing component (53) and the moving component (54). The moving component (54) is used to push the syringe (52) to inject the liquid medicine. A multi-bottle rack (3) is fixedly connected to the upper surface of the housing (2). A protective component (10) is provided on the upper surface of the housing (2). The protective component (10) includes components mounted on the housing. (2) The base (101) on the upper surface, a support rod (102) is fixedly connected to the upper surface of the base (101), a stop block (103) is fixedly connected to one side of the support rod (102), a slide block (105) is slidably connected to the support rod (102), a limit sleeve (106) is installed at one end of the slide block (105), the upper end of the syringe (52) is located on the movement trajectory of the limit sleeve (106), the upper end of the syringe (52) is adapted to the inside of the limit sleeve (106), a positioning seat (107) is fixedly connected to one side of the limit sleeve (106), a swing rod (108) is damped and rotatably connected to the inner wall of the positioning seat (107), a buckle (109) is fixedly connected to one end of the swing rod (108), and a positioning magnet (104) for adsorbing the slide block (105) is installed on the lower surface of the stop block (103). The inner wall of the fixing seat (531) is threaded with a first set screw (533), a first spring (534) is placed inside the fixing seat (531), a first ball bearing platform (535) is slidably connected inside the fixing seat (531), the first spring (534) is located between the first set screw (533) and the first ball bearing platform (535), a first steel ball (536) is placed inside the fixing seat (531), the first steel ball (536) is located below the first ball bearing platform (535), and the first steel ball (536) abuts against the outer shell of the syringe (52); The inner wall of the motion seat (541) is threaded with a second set screw (543). A second spring (544) is placed inside the motion seat (541). A second ball bearing platform (545) is slidably connected inside the motion seat (541). The second spring (544) is located between the second set screw (543) and the second ball bearing platform (545). A second steel ball (546) is placed inside the motion seat (541). The second steel ball (546) is located below the second ball bearing platform (545). The second steel ball (546) abuts against the plunger of the syringe (52). The fixing component (53) includes a fixing seat (531) and a first seat cover (532). The fixing seat (531) is fixedly connected to one side of the mounting plate (51). The first seat cover (532) is installed on the lower surface of the fixing seat (531). The outer shell of the syringe (52) is inserted between the fixing seat (531) and the first seat cover (532). The moving component (54) includes a moving seat (541) and a second seat cover (542). The moving seat (541) is installed on one side of the connecting frame (57). The second seat cover (542) is installed on the upper surface of the moving seat (541). The plunger of the syringe (52) is inserted between the moving seat (541) and the second seat cover (542).

2. The mechanical structure of the positron emission tomography (PET) drug synthesis module according to claim 1, characterized in that: The mounting plate (51) is equipped with an injection pump body (55) on the side away from the syringe (52). A screw (56) is installed at the output end of the injection pump body (55). A moving block (58) is threaded onto the screw (56). One side of the moving block (58) slides against the surface of the mounting plate (51). The end of the connecting bracket (57) away from the moving seat (541) is fixedly connected to the surface of the moving block (58) by bolts.

3. The mechanical structure of the positron emission tomography (PET) drug synthesis module according to claim 2, characterized in that: The mounting plate (51) is fixedly connected to a positioning block (59) on the side near the injection pump body (55), and the upper end of the screw (56) is rotatably connected to the lower surface of the positioning block (59).

4. The mechanical structure of the positron emission tomography (PET) drug synthesis module according to claim 1, characterized in that: The housing (2) has a partition (8) installed inside, and a placement hole (4) is provided on the upper surface of the housing (2). A bracket (9) is installed on the inner top wall of the housing (2), and the bracket (9) is located directly below the placement hole (4).

5. The mechanical structure of the positron emission tomography (PET) drug synthesis module according to claim 1, characterized in that: The upper surface of the base plate (1) is provided with a positioning component (7), and three equally spaced column fixing parts (6) are installed on one side of the housing (2).

6. The mechanical structure of the positron emission tomography (PET) drug synthesis module according to claim 5, characterized in that: The positioning component (7) includes a shielding bracket (71), which is installed on the upper surface of the base plate (1). A lead shielding block (76) is installed on one side of the shielding bracket (71). A flow meter bottom groove (74) is fixedly connected to the upper surface of the base plate (1), and a flow meter bracket (75) is fixedly connected to the upper surface of the base plate (1).

7. The mechanical structure of the positron emission tomography (PET) drug synthesis module according to claim 6, characterized in that: The upper surface of the base plate (1) is fixedly connected to an activity meter frame (72), and the upper surface of the base plate (1) is fixedly connected to an activity meter baffle (73), which is sleeved on the activity meter frame (72).

8. A control system for the mechanical structure of a positron-emitting drug synthesis module, applied to the mechanical structure of the positron-emitting drug synthesis module according to any one of claims 1-7, characterized in that, It includes a host computer, a PLC controller, a sensor group, and an execution component. The host computer is communicatively connected to the PLC controller, the sensor group is connected to the signal input terminal of the PLC controller, and the execution component is connected to the signal output terminal of the PLC controller. The host computer provides a visual operation interface, which supports free selection of synthesis steps, equipment selection and setting of flow rate, temperature, syringe (52) speed and position parameters. The equipment status is distinguished by color, and steps can be changed and locked in real time, adapting to multiple types of nuclear drug synthesis processes. The PLC controller performs logical judgments and closed-loop control, receives the step selection results from the host computer and determines the conditions. Once the conditions are met, it outputs a drive signal. At the same time, it collects real-time data and compares it with the set value to automatically adjust the operating parameters of the execution components. The sensor group collects flow rate, temperature and syringe (52) stroke data in real time, providing a precise basis for parameter control; The actuators drive the pump, regulate the temperature, pump the liquid with the syringe (52), and switch the valve. They work in conjunction with the screw (56) transmission structure to ensure precise operation. The PLC controller integrates start / stop self-test functions, checking the status of mechanical connections, sensors, and pipelines before synthesis, and alarming via indicator lights when abnormalities occur.

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