Rapid fixing and perfusion device for donor liver in liver transplantation

Abstract

The invention belongs to the technical field of medical equipment liver transplantation perfusion, and provides a donor liver rapid fixing perfusion device in liver transplantation. The device comprises a placing box part, the placing box part comprises an outer box and an inner cylinder box, and the inner cylinder box is arranged in the outer box; the inner cylinder box is used for placing a to-be-transplanted liver in liver transplantation; a plurality of inflow holes are formed in the inner cylinder box, and are uniformly formed in the bottom and the cylinder wall of the inner cylinder box; the fixed filling part is arranged at the position of the placing box part; the fixed filling part comprises a fixing assembly and a filling assembly; the fixing assembly comprises at least one fixing liquid sleeve; the stationary liquid sleeve is arranged in the inner barrel box; the stationary liquid sleeve comprises an inner liquid circulation sleeve and an outer gel sleeve; the filling assembly comprises a filling liquid flow pump and a piercing column; the piercing column is arranged in the inner barrel box, and a plurality of micropores are formed in the surface of the piercing column. The device can effectively avoid the epidermis injury of the liver of the donor.

Description

Technical Field

[0001] This invention relates to the field of medical device liver transplant perfusion technology, specifically to a rapid fixation and perfusion device for the donor liver during liver transplantation. Background Technology

[0002] During liver transplantation, perfusion of the transplanted liver is usually required; this mainly involves cleaning and processing the donor liver. However, in actual operation, it is necessary to effectively fix the donor liver, but the epidermis of the donor liver is easily damaged during the cleaning process. Therefore, we propose a rapid fixation and perfusion device for the donor liver during liver transplantation, which can effectively avoid epidermal damage to the donor liver. Summary of the Invention

[0003] To address the shortcomings of existing technologies, this invention provides a rapid fixation and perfusion device for the donor liver during liver transplantation, effectively avoiding damage to the donor liver's epidermis.

[0004] This invention provides a rapid fixation and perfusion device for donor livers during liver transplantation, comprising: a placement box, the placement box comprising an outer box and an inner cylindrical box, the inner cylindrical box being disposed within the outer box; the inner cylindrical box being used to place the liver to be transplanted during liver transplantation; the inner cylindrical box having multiple inflow holes evenly distributed at the bottom and wall of the inner cylindrical box; and a fixing and filling section disposed at the placement box; the fixing and filling section comprising a fixing component and a filling component; and the fixing component comprising at least one fixing liquid sleeve; the fixing liquid sleeve being disposed within the outer box. Inside the inner cylinder; the fixed liquid sleeve includes an inner liquid circulation sleeve and an outer gel sleeve; the inner liquid circulation sleeve contains flowing liquid, and the flowing liquid has a temperature; the outer gel sleeve is disposed on the inner liquid circulation sleeve and covers the inner liquid circulation sleeve; wherein medical gel is sealed between the outer gel sleeve and the inner liquid circulation sleeve; the filling assembly includes a filling liquid flow pump and an insertion column, the filling liquid flow pump pumps the filling liquid from the liquid source through the inlet hole into the inner cylinder; the insertion column is disposed inside the inner cylinder, and the surface of the insertion column is provided with multiple micropores.

[0005] Furthermore, the placement box also includes springs and telescopic cylinders. Multiple springs are evenly distributed between the inner and outer boxes, with one end fixedly connected to the outer box and the other end connected to the inner box. One end of the telescopic cylinder is fixedly connected to the inner box, and the other end is fixedly connected to the outer box. In practical application, the purpose of this design is to achieve oscillating inflow of fluid. This allows for faster filling into the liver to be transplanted compared to traditional drip irrigation. On the one hand, this design ensures that the fluid in the liver to be transplanted is not lost, and on the other hand, the rapidly injected fluid effectively cleanses the area. In actual operation, the telescopic cylinder is a pneumatic cylinder.

[0006] Furthermore, the placement box also includes a flexible protective sleeve, which covers and is installed over the telescopic cylinder, sealing it. In practical applications, this flexible protective sleeve is made of silicone material, effectively utilizing the sealing and elasticity of silicone to protect the telescopic cylinder during its movement. In actual operation, the flexible protective sleeve covers the telescopic cylinder, but the output shaft of the telescopic cylinder is through it and fixedly connected to the inner cylinder box; this design ensures its motion characteristics.

[0007] Furthermore, the fixing assembly also includes a saline tank, a circulation pump, and a main supply pipe. Both ends of the main supply pipe are connected to the saline tank. The main supply pipe has multiple injection branches, each connected to the inner fluid circulation sleeve. The circulation pump is installed at the main supply pipe. In practical applications, the main supply pipe is a flexible tube for easy installation.

[0008] Furthermore, the fixation assembly also includes a one-way valve. The injection pipe has a partition, an inlet, and an outlet; the partition is located between the inlet and the outlet; the one-way valve is installed at the inlet. In practical applications, the purpose of this design is to prevent fluid cross-flow. In actual operation, the partition of this design blocks the inlet and outlet, ensuring that the inlet and outlet can only flow in one direction. The one-way valve further confirms that the fluid flow can only flow in one direction, thus ensuring that the fluid can enter the inner fluid circulation sleeve in one direction. In this way, a fluid circulation effect is achieved. This improves the adaptability of the outer gel sleeve, and the fluctuation of the water flow improves the adaptability to the surface contact of the liver. This enables flexible contact fixation, reducing the need for traditional fixation methods and thus reducing the occurrence of liver damage to the recipient.

[0009] Furthermore, the fixing component also includes a thermoelectric cooling module, which is disposed inside the saline tank and used to adjust the temperature of the saline solution. In practical applications, the purpose of this design is to adjust the water temperature, and thus adjust it to the temperature of the outer gel sleeve. This design can effectively ensure the temperature. The thermoelectric cooling module is also an existing technology module, so it will not be described in detail.

[0010] Furthermore, the filling assembly includes a piston, an injection cylinder, and an inlet sleeve; the inlet sleeve communicates with the outer casing; one end of the injection cylinder is fixedly connected to the piston, the piston is slidably installed inside the inlet sleeve, and reciprocates under the drive of the injection cylinder. In practical applications, the purpose of this design is to inject perfusion fluid; this facilitates the effective entry of perfusion fluid into the inner casing.

[0011] Furthermore, the filling assembly also includes a connecting pipe; the inlet sleeve is also provided with a flow hole, one end of the connecting pipe communicates with the flow hole, and the other end of the connecting pipe communicates with the filling fluid pump. In practical applications, the purpose of this design is to inject perfusion fluid; this facilitates the effective entry of perfusion fluid into the liver. In this way, continuous injection can be achieved during the reciprocating motion of the piston, thus achieving flushing. Repeated fluid flow, through the micropores and inlet hole, achieves effective flushing.

[0012] As can be seen from the above technical solution, the beneficial effects of the rapid fixation and perfusion device for donor liver during liver transplantation provided by the present invention are as follows: In practical applications, the multiple fixation liquid sleeves used in this device effectively achieve a fixed and abutting effect during liver transplantation, and the liquid sleeve design achieves flexible abutment; effectively avoiding damage to the liver during the filling and fixation process. Secondly, the dual-sleeve design employs an inner fluid circulation sleeve that enables effective fluid circulation and ensures fluid undulation. Meanwhile, the outer gel sleeve contains medical gel, which allows for the transmission of fluid undulations to the medical gel. This ensures good contact with the liver surface during the fixation process with the transplanted liver, achieving synchronous movement between the fixation sleeve and the liver and reducing liver damage.

[0013] Furthermore, the flowing fluid has temperature, making it more suitable for transplanted livers and improving their viability; Furthermore, the insertion column effectively locates the transplanted liver, and then the filling fluid is injected into the liver through the filling fluid pump to realize the activity of the transplanted liver. Its multiple micropores effectively ensure that the fluid flow of the filling liver can continuously flow into the liver to be transplanted. Attached Figure Description

[0014] To more clearly illustrate the specific embodiments of the present invention, the accompanying drawings used in the description of the specific embodiments or prior art will be briefly introduced below. In all the drawings, the elements or parts are not necessarily drawn to scale.

[0015] Figure 1 This is a front view of a rapid fixation and perfusion device for donor liver during liver transplantation provided in an embodiment of the present invention; Figure 2 for Figure 1 The enlarged structural diagram at point A is shown below; Figure 3 This is a schematic diagram of the installation of the electric cooling module in a rapid fixation and perfusion device for donor liver during liver transplantation, provided in an embodiment of the present invention. Figure 4 This is a schematic diagram of the operation of a rapid fixation and perfusion device for donor liver during liver transplantation according to the present invention; Figure label: The following components are included: placement box 1, outer box 11, inner cylinder box 12, inlet hole 121, spring 13, telescopic cylinder 14, flexible protective sleeve 15, fixed filling part 2, fixed assembly 21, filling assembly 22, fixed liquid sleeve 211, thermoelectric cooling module 212, inner liquid circulation sleeve 2111, outer gel sleeve 2112, filling liquid flow pump 221, insertion column 222, micropore 2221, piston 223, injection cylinder 224, liquid inlet sleeve 225, connecting pipe 226, liquid outlet 2251, physiological saline tank 23, circulation pump 24, main liquid supply pipe 25, injection branch pipe 251, partition 252, liquid inlet 253, liquid outlet 254, one-way valve 26. Detailed Implementation

[0016] The embodiments of the technical solution of the present invention will now be described in detail with reference to the accompanying drawings. These embodiments are merely illustrative of the technical solution of the present invention and are therefore intended to limit the scope of protection of the present invention.

[0017] The basic implementation examples are as follows: Figures 1 to 4 As shown: like Figure 1 - Figure 4 As shown in this embodiment, a rapid fixation and perfusion device for donor liver during liver transplantation can effectively avoid damage to the donor liver's epidermis.

[0018] This invention provides a rapid fixation and perfusion device for donor liver during liver transplantation, comprising: a placement box 1, which includes an outer box 11 and an inner cylindrical box 12, the inner cylindrical box 12 being disposed within the outer box 11; the inner cylindrical box 12 being used to place the liver to be transplanted during liver transplantation; the inner cylindrical box 12 having multiple inflow holes 121 evenly distributed at the bottom and wall of the inner cylindrical box 12; and a fixing and filling section 2, which is disposed at the placement box 1; the fixing and filling section 2 includes a fixing component 21 and a filling component 22; the fixing component 21 includes at least one fixing liquid sleeve 211; the fixing liquid sleeve 211 is disposed within the inner cylindrical box 12; the fixing liquid sleeve... 211 includes an inner fluid circulation sleeve 2111 and an outer gel sleeve 2112; the inner fluid circulation sleeve 2111 contains a flowing liquid, and the flowing liquid has a temperature; the outer gel sleeve 2112 is disposed on the inner fluid circulation sleeve 2111 and covers the inner fluid circulation sleeve 2111; wherein a medical gel is sealed between the outer gel sleeve 2112 and the inner fluid circulation sleeve 2111; the filling assembly 22 includes a filling liquid flow pump 221 and an insertion post 222, the filling liquid flow pump 221 pumps the filling liquid from the liquid source through the inlet hole 121 into the inner cylinder box 12; the insertion post 222 is disposed in the inner cylinder box 12, and the surface of the insertion post 222 is provided with multiple micropores 2221. In practical applications, the device employs multiple fixation sleeves 211, effectively achieving a fixed and abutting effect during liver transplantation. The sleeve design provides flexible abutment, effectively preventing liver damage during the filling and fixation process. Secondly, the dual-sleeve design, with an inner fluid circulation sleeve 2111 ensuring effective fluid circulation and maintaining fluid fluctuations, and an outer gel sleeve 2112 containing medical gel, allows for the transmission of fluid fluctuations to the medical gel. This ensures good contact with the liver surface during fixation, achieving synchronized movement between the fixation sleeves 211 and the liver, reducing liver damage. Furthermore, the flowing liquid has a temperature, making it more suitable for the transplanted liver and improving its viability. The insertion column 222 effectively positions the transplanted liver, and then the filling fluid pump 221 injects the filling fluid into the liver, activating its viability. The multiple micropores 2221 effectively ensure a continuous flow of filling fluid into the liver to be transplanted.

[0019] In this embodiment, the placement box 1 further includes springs 13 and telescopic cylinders 14. Multiple springs 13 are evenly distributed between the inner cylinder 12 and the outer cylinder 11. One end of each spring 13 is fixedly connected to the outer cylinder 11, and the other end is connected to the inner cylinder 12. One end of the telescopic cylinder 14 is fixedly connected to the inner cylinder 12, and the other end is fixedly connected to the outer cylinder 11. In practical application, the purpose of this design is to achieve oscillating inflow of the liquid. This allows for faster filling into the liver to be transplanted compared to traditional drip irrigation. On the one hand, this design ensures that the fluid in the liver to be transplanted is not lost, and on the other hand, the rapidly injected liquid effectively cleans the area. In actual operation, the telescopic cylinder 14 is a pneumatic cylinder. Simultaneously, during the reciprocating motion of the inner cylinder 12, the filling liquid repeatedly flushes the donor liver, thus achieving the desired cleaning effect.

[0020] To protect the telescopic cylinder 14, in this embodiment, the placement box 1 further includes a flexible protective sleeve 15. The flexible protective sleeve 15 is installed over and around the telescopic cylinder 14 and is used to seal the telescopic cylinder 14. In practical applications, the flexible protective sleeve 15 is made of silicone material, effectively utilizing the sealing and extensibility of silicone. In this way, it can effectively protect the telescopic cylinder 14 during its movement. In actual operation, the flexible protective sleeve 15 covers the telescopic cylinder 14, but the output shaft of the telescopic cylinder 14 is through and fixedly connected to the inner cylinder box 12. This design ensures its movement characteristics.

[0021] In order to adapt to fluctuations, in this embodiment, the fixed component 21 also includes a saline tank 23, a circulation pump 24 and a main supply pipe 25. The two ends of the main supply pipe 25 are respectively connected to the saline tank 23. The main supply pipe 25 is provided with multiple injection branches 251, and the injection branches 251 are respectively connected to the internal fluid circulation sleeve 2111. The circulation pump 24 is installed at the main supply pipe 25.

[0022] In order to achieve unidirectional flow, in this embodiment, the fixing component 21 further includes a one-way valve 26, and the injection branch pipe 251 is provided with a partition 252, an inlet 253 and an outlet 254; the partition 252 is located between the inlet 253 and the outlet 254; the one-way valve 26 is installed at the inlet 253. In practical applications, the purpose of this design is to prevent fluid cross-flow. In actual operation, the partition 252 of this design blocks the inlet 253 and outlet 254, ensuring that the inlet 253 and outlet 254 can only flow in one direction. The one-way valve 26 further confirms that the fluid can only flow in one direction, thus ensuring that the fluid can enter the inner fluid circulation sleeve 2111 in one direction. In this way, the fluid circulation effect is achieved. This also improves the adaptability of the outer gel sleeve 2112. The fluctuation of the water flow improves the adaptability to the surface of the liver, thus achieving flexible contact fixation and reducing the need for traditional fixation methods. This reduces the occurrence of liver damage to the transplanted liver.

[0023] To ensure temperature control, in this embodiment, the fixing component 21 further includes a thermoelectric cooling module 212, which is disposed within the saline solution tank 23 and used to adjust the temperature of the saline solution tank 23. In practical applications, the purpose of this design is to adjust the water temperature, thereby adjusting the temperature of the outer gel sleeve 2112. This design effectively ensures temperature control. The thermoelectric cooling module 212 is an existing technology module, so it will not be described in detail.

[0024] In this embodiment, the filling assembly 22 includes a piston 223, an injection cylinder 224, and an inlet sleeve 225; the inlet sleeve 225 communicates with the outer casing 11; one end of the injection cylinder 224 is fixedly connected to the piston 223, and the piston 223 is slidably installed inside the inlet sleeve 225 and reciprocates under the drive of the injection cylinder 224. In practical applications, the purpose of this design is to inject perfusion fluid; this facilitates the effective entry of perfusion fluid into the liver. In this embodiment, the filling assembly 22 further includes a connecting pipe 226; the inlet sleeve 225 is also provided with a flow hole 2251, one end of the connecting pipe 226 communicates with the flow hole 2251, and the other end of the connecting pipe 226 communicates with the filling fluid pump 221. In practical applications, the purpose of this design is to inject perfusion fluid; this facilitates the effective entry of perfusion fluid into the liver. In this way, continuous injection can be achieved during the reciprocating motion of the piston 223, thus achieving flushing. Repeated fluid flow, through the micropores 2221 and the inlet hole 121, achieves effective flushing.

[0025] In summary, this rapid fixation and perfusion device for donor liver during liver transplantation is not only rationally designed but also simple to operate. It can effectively clean and process the donor liver and effectively avoid damage to the donor liver epithelium. Therefore, this device is suitable for industry promotion.

[0026] The above embodiments are only used to illustrate the technical solutions of the present invention, and are not intended to limit it. Although the present invention has been described in detail with reference to the foregoing embodiments, those skilled in the art should understand that modifications can still be made to the technical solutions described in the foregoing embodiments, or equivalent substitutions can be made to some or all of the technical features therein. Such modifications or substitutions do not cause the essence of the corresponding technical solutions to deviate from the scope of the technical solutions of the embodiments of the present invention, and they should all be covered within the scope of the claims and specification of the present invention.

Claims

1. A rapid fixation and perfusion device for donor liver during liver transplantation, characterized in that, include: The placement box includes an outer box and an inner cylindrical box, with the inner cylindrical box disposed inside the outer box. The inner cylindrical box is used to place the liver to be transplanted in a liver transplant. The inner cylindrical box is provided with multiple inflow holes, which are evenly distributed on the bottom and wall of the inner cylindrical box. A fixed filling section is provided at the placement box section; the fixed filling section includes a fixing component and a filling component; and The fixing component includes at least one fixing liquid sleeve; the fixing liquid sleeve is disposed inside the inner cylinder; the fixing liquid sleeve includes an inner liquid circulation sleeve and an outer gel sleeve; the inner liquid circulation sleeve contains flowing liquid, and the flowing liquid has a temperature; the outer gel sleeve is disposed on the inner liquid circulation sleeve and covers the inner liquid circulation sleeve; wherein a medical gel is sealed between the outer gel sleeve and the inner liquid circulation sleeve. The filling assembly includes a filling liquid pump and an insertion post. The filling liquid pump pumps the filling liquid from the liquid source through the inlet hole into the inner cylinder. The insertion post is disposed in the inner cylinder, and the surface of the insertion post is provided with multiple micropores.

2. The rapid fixation and perfusion device for donor liver during liver transplantation according to claim 1, characterized in that, The placement box section also includes springs and telescopic cylinders. The springs are provided in multiple locations and are evenly distributed between the inner cylinder and the outer cylinder. One end of the spring is fixedly connected to the outer cylinder, and the other end of the spring is connected to the inner cylinder. One end of the telescopic cylinder is fixedly connected to the inner cylinder, and the other end of the telescopic cylinder is fixedly connected to the outer cylinder.

3. The rapid fixation and perfusion device for donor liver during liver transplantation according to claim 2, characterized in that, The placement box also includes a flexible protective sleeve, which is installed over the telescopic cylinder and is used to seal the telescopic cylinder.

4. The rapid fixation and perfusion device for donor liver during liver transplantation according to claim 1, characterized in that, The fixed assembly also includes a saline tank, a circulation pump, and a main supply pipe. Both ends of the main supply pipe are connected to the saline tank. The main supply pipe has multiple injection branches, each of which is connected to the internal fluid circulation sleeve. The circulation pump is installed at the main supply pipe.

5. The rapid fixation and perfusion device for donor liver during liver transplantation according to claim 4, characterized in that, The fixing assembly also includes a one-way valve, and the injection branch pipe is provided with a partition, an inlet and an outlet; the partition is located between the inlet and the outlet; the one-way valve is installed at the inlet.

6. The rapid fixation and perfusion device for donor liver during liver transplantation according to claim 4, characterized in that, The fixing component also includes a thermoelectric cooling module, which is disposed inside the saline tank and is used to adjust the temperature of the saline tank.

7. The rapid fixation and perfusion device for donor liver during liver transplantation according to claim 1, characterized in that, The filling assembly includes a piston, an injection cylinder, and an inlet sleeve; the inlet sleeve communicates with the outer casing; one end of the injection cylinder is fixedly connected to the piston, the piston is slidably installed inside the inlet sleeve, and reciprocates under the drive of the injection cylinder.

8. A rapid fixation and perfusion device for donor liver during liver transplantation according to claim 7, characterized in that, The filling assembly also includes a connecting pipe; the liquid inlet sleeve is also provided with a liquid outlet, one end of the connecting pipe is connected to the liquid outlet, and the other end of the connecting pipe is connected to the filling liquid flow pump.

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