Method and system for online monitoring of separation column resin saturation

Abstract

The application discloses a separation column resin saturation online monitoring method and system, and belongs to the technical field of medical apparatuses, which comprises the following steps: acquiring real-time acoustic impedance data of the inlet end and the outlet end of the separation column; calculating the instantaneous difference value of the real-time acoustic impedance data of the inlet end and the outlet end as the real-time acoustic impedance instantaneous difference value; measuring the radial blood flow velocity distribution of the middle section of the separation column and generating a flow field disturbance factor according to the radial blood flow velocity distribution; applying a local pulse thrust to the resin bed layer in the separation column and acquiring the instantaneous acoustic impedance difference value after disturbance; and generating a relaxation recovery curve according to the change of the instantaneous acoustic impedance difference value after disturbance with time. The application can overcome the problem that the existing monitoring method cannot adapt to the blood non-Newtonian fluid characteristics and the interference of flow field dynamic fluctuations on the monitoring signal, so as to eliminate the non-absorption signal deviation caused by the flow field fluctuations and further improve the resin saturation monitoring accuracy.

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