Adjustable sampling device for cross-matching blood test
By designing an automated crossmatch testing device, which utilizes mechanical structures and motor drives to achieve automated sampling and mixing, the problems of cumbersome operation and long time consumption in existing technologies are solved, thereby improving testing efficiency.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- THE AFFILIATED HOSPITAL OF SOUTHWEST MEDICAL UNIV
- Filing Date
- 2024-03-14
- Publication Date
- 2026-05-08
AI Technical Summary
Existing crossmatch testing procedures are cumbersome, time-consuming, and inefficient, and cannot achieve automated sampling and mixing.
An adjustable sampling device was designed, comprising components such as a bidirectional lead screw, a servo motor, transmission gears, a dropper, and an air bladder. The device achieves automated sampling and dispensing through mechanical structure and motor drive. With the motor drive for dropper position adjustment and dropper replacement, automated sampling and mixing are also achieved.
This improved the efficiency of crossmatch testing, reduced manual operation time, and ensured the accuracy and efficiency of sample mixing.
Smart Images
Figure CN121994540A_ABST
Abstract
Description
Technical Field
[0001] This invention relates to the field of medical device technology, specifically to an adjustable sampling device for crossmatch testing. Background Technology
[0002] Crossmatch testing involves adding serum from the recipient to a suspension of red blood cells from the donor, and vice versa, while simultaneously performing an agglutination test. Currently, hospitals lack dedicated crossmatch testing kits. Medical staff must inject the recipient's serum into test tube A, then inject the donor's red blood cell suspension into test tube A, then inject the donor's serum into test tube B, and finally inject the recipient's red blood cell suspension into test tube B. The agglutination test is then performed on both test tubes A and B.
[0003] Currently, existing crossmatch testing involves medical staff manually taking samples with a dropper. During the testing process, the serum from the donor and recipient needs to be sampled and mixed multiple times before finally being added to the crossmatching solution to complete the test. This operation is cumbersome, and the time spent on manual sampling and mixing is long, resulting in low testing efficiency. Therefore, we propose an adjustable sampling device for crossmatch testing. Summary of the Invention
[0004] To address the shortcomings of existing technologies, this invention provides an adjustable sampling device for crossmatch testing, which solves the problems mentioned in the background section.
[0005] To achieve the above objectives, the present invention provides the following technical solution: an adjustable sampling device for crossmatch testing, comprising a device body, a bidirectional lead screw rotatably mounted on the top of the device body, a first servo motor fixedly mounted on one side of the top of the device body, a transmission gear fixedly mounted on the output end of the first servo motor, a driven gear fixedly mounted on the outer side of the bidirectional lead screw, the driven gear meshing with the transmission gear, a limit rod fixedly mounted inside the device body above the bidirectional lead screw, two first sliders threadedly mounted on the outer side of the bidirectional lead screw, the first sliders slidably connected to the limit rod, and a first telescopic rod fixedly mounted on the bottom of the first sliders. An installation block is fixedly installed at the output end of the first telescopic rod. A snap-fit groove is formed inside the installation block, and a dropper is snapped into the groove. An air bladder is provided at the top of the dropper, and the air bladder cooperates with the snap-fit groove. Side grooves are formed inside the installation block on both sides of the snap-fit groove. A sliding rod is slidably installed inside the side groove. A snap-fit block is fixedly installed at one end of the sliding rod, and the snap-fit block cooperates with the air bladder. A first spring is installed on the outside of the sliding rod. Guide rods are fixedly installed on both sides of the other end of the sliding rod. Two guide plates are fixedly installed at the bottom of the first slider on both sides of the first telescopic rod. Guide grooves are formed inside the guide plates, and the guide rods are slidably connected to the guide grooves.
[0006] Preferably, drive boxes are fixedly installed on both sides inside the main body of the device. A sliding groove is opened inside the drive box. A second servo motor is fixedly installed on one side of the drive box. A threaded rod is fixedly installed inside the sliding groove at the output end of the second servo motor. A second slider is threadedly installed on the outer side of the threaded rod. An installation plate is fixedly installed on one side of the second slider. Several second telescopic rods are fixedly installed on the top of the installation plate. A placement block is fixedly installed at the output end of the second telescopic rod. An insertion hole is opened inside the placement block. The dropper mates with the insertion hole.
[0007] Preferably, a partition is fixedly installed inside the main body of the device, and through slots are opened on both sides of the partition. A collection box is placed inside the main body of the device and below the through slots.
[0008] Preferably, a third motor is fixedly installed at the bottom inside the main body of the device. The output end of the third motor passes through the interior of the partition and is fixedly installed with a mounting plate. The top of the mounting plate has a mounting groove, and a placement frame is engaged inside the mounting groove. Pull grooves are opened on both sides of the mounting plate, and pins are slidably installed inside the pull grooves. A pull plate is fixedly installed on the outside of the pin, and a second spring is installed on the outside of the pin and on one side of the pull plate. Pin holes are opened on both sides of the placement frame. One end of the pin extends to the inside of the mounting groove and engages with the pin hole. Several test tubes are placed inside the top of the placement frame, and the dropper engages with the test tubes.
[0009] Preferably, the top of the main body of the device is provided with a plurality of test solution tanks, the bottom of the test solution tanks is provided with a metering pump, and the output end of the metering pump extends to the inside of the main body of the device and is fixedly installed with a drip tube, which is used in conjunction with the test tube.
[0010] Preferably, one end of the first spring is fixedly connected to the inner wall of one side of the side groove, and the other end of the first spring is fixedly connected to the snap-fit block.
[0011] Preferably, the first slider has a hole inside that mates with the bidirectional lead screw and the limiting rod.
[0012] Preferably, the inner side of the snap-fit block is provided with an anti-slip block, which cooperates with the airbag.
[0013] Preferably, a door is provided on one side of the main body of the device, and a controller is provided on the outside of the main body of the device.
[0014] This invention provides an adjustable sampling device for crossmatch testing, which has the following advantages:
[0015] 1. This adjustable sampling device for crossmatch testing, through the cooperation of a bidirectional lead screw, a first servo motor, a transmission gear, a driven gear, a limit rod, a first slider, a first telescopic rod, a mounting block, a locking groove, a dropper, an air bladder, a side groove, a sliding rod, a locking block, a first spring, a guide rod, a guide plate, and a guide groove, can automatically adjust the position of the dropper according to the position of the test tubes containing donor and recipient serum and the position of unused test tubes during crossmatch testing. Subsequently, the donor and recipient serum are sampled and dripped into the test tube to be dripped. It can also simultaneously sample and test the donor and recipient serum, resulting in high work efficiency.
[0016] 2. This adjustable sampling device for crossmatch testing, through the cooperation of a drive box, slide groove, second servo motor, threaded rod, second slider, mounting plate, second telescopic rod, placement block, and insertion hole, allows the used dropper installed inside the mounting block to be discarded after one sampling. Then, by moving it above the placement block and opening the second telescopic rod, the dropper can be automatically replaced, meeting the sampling requirements of the test and avoiding the situation where mixed dropper samples affect the test results.
[0017] 3. This adjustable sampling device for crossmatch testing, through the cooperation of a third motor, mounting plate, mounting slot and placement rack, allows the placement rack to be adjusted to rotate, thereby adjusting the position of the test tube below the dropper, so that the test solution can be dripped into the test tube. After the serum and solution are mixed, the mounting plate is driven by the third motor to rotate, and centrifugation is performed to complete the test. Attached Figure Description
[0018] Figure 1 This is a schematic diagram of the structure of the present invention;
[0019] Figure 2 This is a side sectional view of the present invention;
[0020] Figure 3 This is a schematic diagram of the dropper replacement method of the present invention;
[0021] Figure 4 For the present invention Figure 1 Enlarged view of point A in the image;
[0022] Figure 5 For the present invention Figure 1 Enlarged view of point B in the image;
[0023] Figure 6 For the present invention Figure 3 Enlarged view of point C in the image;
[0024] Figure 7 For the present invention Figure 1 Enlarged view of point D in the image;
[0025] Figure 8 This is a top sectional view of the mounting block of the present invention.
[0026] In the diagram: 1. Main body of the device; 2. Bidirectional lead screw; 3. First servo motor; 4. Transmission gear; 5. Driven gear; 6. Limiting rod; 7. First slider; 8. First telescopic rod; 9. Mounting block; 10. Snap-fit groove; 11. Dropper; 12. Airbag; 13. Side groove; 14. Slide rod; 15. Snap-fit block; 16. First spring; 17. Guide rod; 18. Guide plate; 19. Guide groove; 20. Drive box; 21. Slide groove; 22. Threaded rod; 23. 24. Second slider; 25. Mounting plate; 26. Second telescopic rod; 27. Placement block; 28. Insertion hole; 29. Partition plate; 30. Through groove; 31. Collection box; 32. Third motor; 33. Mounting plate; 34. Placement rack; 35. Pull groove; 36. Pin; 37. Pull plate; 38. Second spring; 39. Pin hole; 40. Test tube; 41. Test solution tank; 42. Metering pump; 43. Dropping tube; 44. Second servo motor. Detailed Implementation
[0027] The technical solutions of the present invention will be clearly and completely described below with reference to the accompanying drawings of the embodiments of the present invention. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments.
[0028] Please see Figures 1 to 8 This invention provides a technical solution: an adjustable sampling device for crossmatch testing, comprising a device body 1, a door on one side of the device body 1, and a controller on the outside of the device body 1. A first servo motor 3, a first telescopic rod 8, a second servo motor 44, a second telescopic rod 25, a third motor 31, and a quantitative pump 42 are all electrically connected to the controller. Several test solution tanks 41 are located on the top of the device body 1, and a quantitative pump 42 is located at the bottom of each test solution tank 41. The output end of the quantitative pump 42 extends to the inside of the device body 1 and is fixedly fitted with a drip tube 43, which cooperates with a test tube 40. The test solution tanks 41 contain crossmatch testing solutions such as physiological saline, agglutinating amine, deagglutination solution, and low ionic strength solution. The input end of the quantitative pump 42 extends into the interior of the test solution tanks 41. By activating the quantitative pump 42, the solution in the test solution tanks 41 can be exported and then dripped into the test tubes 40 through the drip tube 43.
[0029] A bidirectional lead screw 2 is rotatably mounted on the top of the device body 1. A first servo motor 3 is fixedly mounted on one side of the top of the device body 1. A transmission gear 4 is fixedly mounted on the output end of the first servo motor 3. A driven gear 5 is fixedly mounted on the outer side of the bidirectional lead screw 2, and the driven gear 5 meshes with the transmission gear 4. A limit rod 6 is fixedly mounted inside the device body 1 above the bidirectional lead screw 2. Two first sliders 7 are threadedly mounted on the outer side of the bidirectional lead screw 2. The first sliders 7 are slidably connected to the limit rod 6. The first sliders 7 have holes inside that mate with the bidirectional lead screw 2 and the limit rod 6. A first telescopic rod 8 is fixedly mounted on the bottom of the first sliders 7. A mounting block 9 is fixedly mounted on the output end of the first telescopic rod 8. A snap-fit groove 10 is opened inside the mounting block 9. A dropper 11 is snapped into the snap-fit groove 10. An air bladder 12 is provided on the top of the dropper 11, and the air bladder 12 mates with the snap-fit groove 10. Side grooves 13 are opened inside the mounting block 9 on both sides of the snap-fit groove 10. A slide rod 14 is slidably mounted inside the side grooves 13. A locking block 15 is fixedly installed at one end of the slide rod 14. The locking block 15 cooperates with the airbag 12. An anti-slip block is provided on the inner side of the locking block 15, which cooperates with the airbag 12. A first spring 16 is installed on the outer side of the slide rod 14. One end of the first spring 16 is fixedly connected to the inner wall of one side of the side groove 13, and the other end of the first spring 16 is fixedly connected to the locking block 15. Guide rods 17 are fixedly installed on both sides of the other end of the slide rod 14. Two guide rods 17 are fixedly installed at the bottom of the first slider 7 and on both sides of the first telescopic rod 8. The guide plate 18 has a guide groove 19 inside. The guide rod 17 is slidably connected to the guide groove 19. The top of the guide groove 19 is offset outward and the bottom of the guide groove 19 is offset inward. When the first telescopic rod 8 pushes the mounting block 9 down, the guide rod 17 will move inward through the guide groove 19, thereby squeezing the airbag 12 through the snap-fit block 15. The bottom of the dropper 11 is submerged in the sampled serum. Then, when the first telescopic rod 8 drives the mounting block 9 to reset, the snap-fit block 15 slowly resets, and the serum is sucked into the dropper 11.
[0030] A partition 28 is fixedly installed inside the main body 1 of the device. A through groove 29 is opened on both sides of the partition 28. A collection box 30 is placed inside the main body 1 and below the through groove 29. The main function of the through groove 29 and the collection box 30 is that after the dropper 11 installed at the bottom of the mounting block 9 is completed and moves to both sides inside the main body 1, the mounting block 9 is driven to rise by the first telescopic rod 8. Then, the guide rod 17 is pulled through the guide groove 19, which in turn drives the slide rod 14 and the locking block 15 to move to both sides. Subsequently, the airbag 12 will fall into the collection box 30 by gravity.
[0031] Both sides of the main body 1 of the device are fixedly installed with drive boxes 20. The drive box 20 has a slide groove 21 inside. A second servo motor 44 is fixedly installed on one side of the drive box 20. The output end of the second servo motor 44 extends into the slide groove 21 and is fixedly installed with a threaded rod 22. A second slider 23 is threaded on the outside of the threaded rod 22. A mounting plate 24 is fixedly installed on one side of the second slider 23. Several second telescopic rods 25 are fixedly installed on the top of the mounting plate 24. A placement block 26 is fixedly installed at the output end of the second telescopic rod 25. An insertion hole 27 is opened inside the placement block 26. The dropper 11 is engaged with the insertion hole 27.
[0032] A third motor 31 is fixedly installed at the bottom inside the main body 1. The output end of the third motor 31 passes through the interior of the partition 28 and is fixedly installed on a mounting plate 32. The top of the mounting plate 32 has an internal mounting groove 33, and a placement rack 34 is snapped into the groove 33. The placement rack 34 is rectangular and box-shaped, with several slots on its top for holding test tubes. Pull grooves 35 are formed on both sides of the mounting plate 32, and pins 36 are slidably installed inside the pull grooves 35. A pull plate 37 is fixedly installed on the outside of the pins 36, and a [missing information - likely a device or component] is installed on the outside of the pins 36 and on one side of the pull plate 37. The second spring 38 and the inside of both sides of the placement rack 34 are provided with pin holes 39. One end of the pin 36 extends to the inside of the mounting groove 33 and cooperates with the pin hole 39. Several test tubes 40 are placed inside the top of the placement rack 34. The dropper 11 cooperates with the test tubes 40. Among the several test tubes 40 placed inside the placement rack 34, the two adjacent ones are the donor and recipient serum, respectively. The other test tubes 40 are used for sampling and mixing. The main functions of the pull groove 35, the pin 36, the pull plate 37, the second spring 38 and the pin hole 39 are to facilitate the installation and fixation of the placement rack 34.
[0033] In summary, this adjustable sampling device for crossmatch testing is used by first placing the test tube 40 containing donor and recipient serum into the slot at the top of the placement rack 34. Then, pulling the pin 36 retracts one end into the pull groove 35, allowing the placement rack 34 to be placed into the mounting slot 33. Releasing the pin 36 causes the second spring 38 to return and reset the pin 36, allowing it to re-enter the pin hole 39. Crossmatch testing can then begin. The controller controls the first servo motor 3 to drive the transmission gear 4, which in turn meshes with the driven gear 5, rotating the bidirectional lead screw 2. This drives the two outer first sliders 7 to move via threads above the test tube 40 containing donor and recipient blood. Then, the first telescopic rod 8 can be activated, pushing the mounting block 9 downwards. This causes the two guide rods 17 on both sides of the mounting block 9 to move inwards via the guide groove 19. As the guide rods 17 move, they push the locking block 15 into the locking groove 10 via the sliding rod 14. The locking block 15 then compresses the airbag 12, causing the air inside the airbag 12 to be expelled from the bottom of the dropper 11. At the same time, the bottom of the dropper 11 is submerged in the blood sample in the test tube 40. Then, the first telescopic rod 8 drives the mounting block 9 upwards, and the guide groove 19 drives the guide rods 17 to move to both sides while the locking block 15 moves into the side groove 13. The airbag 12 then rebounds, sucking the sample into the dropper 11. Finally, the controller activates the first servo motor 3 to drive the first sliding rod 15. Block 7 moves above the test tube 40 containing the sample. Then, by pushing down the first telescopic rod 8, the airbag 12 is squeezed, causing the sample drawn into the dropper 11 to drip into the test tube 40. Subsequently, the controller activates the third motor 31, driving the mounting plate 32 and the placement rack 34 to rotate, thus rotating the test tube 40 below the dropper 43. The metering pump 42 is then activated, dripping the test solution from the test solution container 41 into the test tube 40. After the test solution is added, the third motor 31 is activated again, driving the mounting plate 32 to rotate, mixing the blood sample with the solution in the test tube 40. Once the dropper 11 has completed sampling, the first servo motor 3 drives the first slider 7 to move to both sides inside the main body 1. Then, the controller... When the device is activated, the first telescopic rod 8 moves the mounting block 9 upward, which in turn pulls the guide rod 17 to move to both sides via the guide groove 19. After the guide rod 17 moves, it pulls the locking block 15 into the side groove 13 via the slide rod 14, thus releasing the restriction on the airbag 12. Subsequently, the dropper 11 and the airbag 12 will fall into the collection box 30 by gravity. Then, the controller activates the second servo motor 44, which drives the threaded rod 22 to rotate, thereby driving the second slider 23 to move through the thread, moving a placement block 26 and the dropper 11 to below the mounting block 9. Then, the second telescopic rod 25 is activated, which pushes the placement block 26, the dropper 11, and the airbag 12 upward, and the airbag 12 inserts into the locking groove 10.Then, the first telescopic rod 8 pushes the mounting block 9 down, allowing the airbag 12 to be clamped and fixed by the snap-fit block 15, completing the replacement. The overall operation is convenient and quick.
[0034] The above description is only a preferred embodiment of the present invention, but the scope of protection of the present invention is not limited thereto. Any equivalent substitutions or modifications made by those skilled in the art within the scope of the technology disclosed in the present invention, based on the technical solution and inventive concept of the present invention, should be covered within the scope of protection of the present invention.
Claims
1. An adjustable sampling device for crossmatch testing, comprising a device body (1), characterized in that: A bidirectional lead screw (2) is rotatably mounted on the top of the device body (1). A first servo motor (3) is fixedly mounted on one side of the top of the device body (1). A transmission gear (4) is fixedly mounted on the output end of the first servo motor (3). A driven gear (5) is fixedly mounted on the outer side of the bidirectional lead screw (2). The driven gear (5) meshes with the transmission gear (4). A limit rod (6) is fixedly mounted inside the device body (1) and above the bidirectional lead screw (2). Two first sliders (7) are threaded on the outer side of the bidirectional lead screw (2). The first sliders (7) are slidably connected to the limit rod (6). A first telescopic rod (8) is fixedly mounted on the bottom of the first sliders (7). An installation block (9) is fixedly mounted on the output end of the first telescopic rod (8). A snap-fit groove (10) is opened inside the installation block (9). A dropper (11) is snapped into the inside of the groove (10). An air bladder (12) is provided at the top of the dropper (11). The air bladder (12) cooperates with the snap-fit groove (10). Side grooves (13) are provided inside the mounting block (9) and on both sides of the snap-fit groove (10). A slide rod (14) is slidably installed inside the side groove (13). A snap-fit block (15) is fixedly installed at one end of the slide rod (14). The snap-fit block (15) cooperates with the air bladder (12). A first spring (16) is installed on the outside of the slide rod (14). Guide rods (17) are fixedly installed on both sides of the other end of the slide rod (14). Two guide plates (18) are fixedly installed at the bottom of the first slider (7) and on both sides of the first telescopic rod (8). A guide groove (19) is provided inside the guide plate (18). The guide rod (17) is slidably connected to the guide groove (19).
2. The adjustable sampling device for crossmatch testing according to claim 1, characterized in that: Both sides of the main body (1) of the device are fixedly installed with drive boxes (20). The drive box (20) has a sliding groove (21) inside. A second servo motor (44) is fixedly installed on one side of the drive box (20). The output end of the second servo motor (44) extends into the sliding groove (21) and is fixedly installed with a threaded rod (22). A second slider (23) is threaded on the outside of the threaded rod (22). An installation plate (24) is fixedly installed on one side of the second slider (23). Several second telescopic rods (25) are fixedly installed on the top of the installation plate (24). A placement block (26) is fixedly installed at the output end of the second telescopic rod (25). An insertion hole (27) is opened inside the placement block (26). The dropper (11) is engaged with the insertion hole (27).
3. The adjustable sampling device for crossmatch testing according to claim 1, characterized in that: A partition (28) is fixedly installed inside the main body (1) of the device. A through groove (29) is opened on both sides of the partition (28). A collection box (30) is placed inside the main body (1) and below the through groove (29).
4. An adjustable sampling device for crossmatch testing according to claim 1, characterized in that: A third motor (31) is fixedly installed at the bottom inside the main body (1) of the device. The output end of the third motor (31) is fixedly installed with a mounting plate (32) through the interior of the partition (28). A mounting groove (33) is opened inside the top of the mounting plate (32). A placement rack (34) is snapped into the interior of the mounting groove (33). Pull grooves (35) are opened inside both sides of the mounting plate (32). A pin (36) is slidably installed inside the pull groove (35). A pull plate (37) is fixedly installed on the outside of the pin (36). A second spring (38) is installed on the outside of the pin (36) and on one side of the pull plate (37). Pin holes (39) are opened inside both sides of the placement rack (34). One end of the pin (36) extends to the inside of the mounting groove (33) and cooperates with the pin hole (39). Several test tubes (40) are placed inside the top of the placement rack (34). The dropper (11) cooperates with the test tubes (40).
5. An adjustable sampling device for crossmatch testing according to claim 1, characterized in that: The top of the main body (1) of the device is provided with several test solution tanks (41), and the bottom of the test solution tanks (41) is provided with a metering pump (42). The output end of the metering pump (42) extends to the inside of the main body (1) of the device and is fixedly installed with a drip tube (43). The drip tube (43) is used in conjunction with the test tube (40).
6. An adjustable sampling device for crossmatch testing according to claim 1, characterized in that: One end of the first spring (16) is fixedly connected to the inner wall of one side of the side groove (13), and the other end of the first spring (16) is fixedly connected to the snap-fit block (15).
7. An adjustable sampling device for crossmatch testing according to claim 1, characterized in that: The first slider (7) has a hole inside that cooperates with the bidirectional lead screw (2) and the limiting rod (6).
8. An adjustable sampling device for crossmatch testing according to claim 1, characterized in that: The inner side of the snap-fit block (15) is provided with an anti-slip block, which cooperates with the airbag (12).
9. An adjustable sampling device for crossmatch testing according to claim 1, characterized in that: A door is provided on one side of the main body (1) of the device, and a controller is provided on the outside of the main body (1).