Application of bacillus coagulans JA845 in preparation of health care product or food for assisting in lowering blood pressure

Health products or foods prepared using Bacillus coagulans JA845 utilize their antioxidant properties to fill the technological gap in adjunctive treatment of hypertension, achieving safe and effective blood pressure reduction and improving arterial health.

CN122004472APending Publication Date: 2026-05-12JILIN ACAD OF AGRI SCI
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Patent Information

Application Number
CN202610074903.7
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2026-01-20
Publication Date
2026-05-12

AI Technical Summary

Technical Problem

There is no existing technology regarding the use of Bacillus coagulans, which has unique antioxidant activity, as an adjunct treatment for hypertension, and there is a lack of safe and effective means of lowering blood pressure.

Method used

Using Bacillus coagulans JA845 as a probiotic, health products or foods that help lower blood pressure are prepared. By utilizing its antioxidant effects, it regulates the intestinal flora, inhibits angiotensin-converting enzyme activity, reduces systolic blood pressure, improves arterial vascular pathological characteristics, reduces the secretion of adhesion factors, inhibits inflammatory responses and angiotensin secretion, and enhances antioxidant capacity.

Benefits of technology

It significantly reduces systolic blood pressure in hypertensive model rats, improves arterial vascular pathology, reduces the levels of adhesion factors and inflammatory factors, inhibits angiotensin secretion, and enhances antioxidant capacity, achieving a safe and effective blood pressure-lowering effect.

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Abstract

The invention provides application of bacillus coagulans JA845 in preparation of health-care products or food for assisting in lowering blood pressure, and belongs to the technical field of health-care products. The bacillus coagulans JA845 has unique physiological activity, the bacillus coagulans JA845 is found and proved to have the effect of assisting in lowering blood pressure for the first time, the application blank of the bacillus coagulans in the field of hypertension adjuvant therapy is filled, the action mode of improving the vascular function by taking antioxidation as a core mechanism has uniqueness, and the bacillus coagulans JA845 can be applied to the field of hypertension adjuvant therapy. And a new microbial preparation selection is provided for adjuvant therapy of hypertension.
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