Microdroplet photodynamic therapy compositions for the treatment of squamous cell carcinoma of the skin and mucosa and methods of making same

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The combination of aminolevulinic acid hydrochloride and lidocaine hydrochloride, administered via microdroplet injection, has been used to treat squamous cell carcinoma of the skin and mucous membranes. This method solves the problems of drug penetration and pain control, achieving efficient lesion clearance and functional preservation, and is suitable for treatment of various sensitive sites.

CN122097577APending Publication Date: 2026-05-29HENAN CANCER HOSPITAL

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Patent Information

Authority / Receiving Office: CN · China
Patent Type: Applications(China)
Current Assignee / Owner: HENAN CANCER HOSPITAL
Filing Date: 2026-04-02
Publication Date: 2026-05-29

Application Information

Patent Timeline

02 Apr 2026

Application

29 May 2026

Publication

CN122097577A

IPC: A61K41/00; A61K31/167; A61K9/00; A61P35/00; A61P17/00

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Application Domain

Organic active ingredients Energy modified materials

Technology Topics

Anesthetic AgentSquamous Carcinomas

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Abstract

The present application relates to a kind of microdroplet photodynamic therapy compositions for treating skin and mucous membrane squamous cell carcinoma and its preparation method, belong to medical technical field.The microdroplet photodynamic therapy compositions for treating skin and mucous membrane squamous cell carcinoma, including photosensitizer precursor, anesthetic and solvent, the mass final concentration of the photosensitizer precursor is 15-25 %, the mass final concentration of the anesthetic is 4-6 %, and the photosensitizer precursor is hydrochloric acid aminolevulinic acid.The microdroplet photodynamic therapy compositions for treating skin and mucous membrane squamous cell carcinoma prepared by the present application adopts the mode of microdroplet injection, solves the three big problems of drug delivery, function preservation and pain control commonly faced in the treatment of different sensitive parts (face, hand, genital organ, tongue), enhances the practicability of the microdroplet photodynamic therapy compositions for treating skin and mucous membrane squamous cell carcinoma of the present application.

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