Gating parameter setting method, signal acquisition method and device, and imaging system
By tuning the gating parameters in a multiphoton imaging system, the time delay and width of the fluorescent analog electrical signal are precisely matched, solving the problem of low signal-to-noise ratio and achieving the generation of high-quality images. This method is applicable to imaging systems with different laser repetition frequencies.
CN122109037APending Publication Date: 2026-05-29NANJING TRANSCEND VIVOSCOPE BIO TECH CO LTD
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- NANJING TRANSCEND VIVOSCOPE BIO TECH CO LTD
- Filing Date
- 2026-02-26
- Publication Date
- 2026-05-29
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Figure CN122109037A_ABST
Abstract
The application discloses a gating parameter setting method, a signal acquisition method of an imaging system, a signal acquisition device of the imaging system and the imaging system. The gating parameter setting method comprises the following steps: acquiring a laser pulse signal emitted by a laser; generating a gating signal, the gating signal is synchronous with the acquired laser pulse signal, and an initial gating width of the gating signal is adjusted to a preset width; determining a target time delay and a target gating width of the gating signal based on a fluorescent analog electric signal excited by the laser pulse signal, and the target gating width is matched with a duration of the fluorescent analog electric signal. According to the method, the sampling time period is matched with the duration of the fluorescent analog electric signal by optimizing the gating parameter, and therefore, the signal-to-noise ratio of the data acquired by the imaging system is improved.
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