A SPECT and PET translation switching CT combined imaging device and imaging method

Abstract

A SPECT and PET translational switching CT combined imaging device includes a fixed part (1), an object bed (2), a PET-SPECT device (3), a front plate (4), a CT device (5), and a rear plate (6). The fixed part includes a front base (11), a rear base (12), and an object bed seat (13). The object bed includes a slide (21), a support device (22), and a bed body (23); the bed body is slidably fixed on the support device. The PET-SPECT device is mounted on a horizontal double guide rail (41) on the front side of the front plate; the CT device is mounted between a rotary drive device (42) on the rear side of the front plate and a rear bearing (61) on the rear plate; the PET-SPECT device includes a main plate (31), a SPECT plate (32), a SPECT device (33), a PET plate (34), and a PET device (35). A SPECT and PET translational switching CT combined imaging method is implemented using the combined imaging device.

Description

Technical Field

[0001] This invention relates to the field of SPECT-CT-PET combined imaging technology with special structures, specifically to a SPECT and PET translation-switching CT combined imaging device and imaging method. Background Technology

[0002] SPECT (Single-Photon Emission Computed Tomography) is one of the two ECT (Emission Computed Tomography) techniques in nuclear medicine imaging. It uses radiopharmaceuticals that emit only a single photon with each decay to create tomographic images, revealing the distribution of the drug within the organism and reflecting its functional, metabolic, and physiological state. Compared to PET, SPECT has both advantages and disadvantages; overall, it is one of the more important methods for detecting nuclear medicine imaging and is widely used in clinical settings.

[0003] Besides its clinical applications, SPECT is now widely used in small animal drug research. Due to the increased safety margin, small animals can withstand more radiation / exposure than human medical studies, making SPECT less restricted in small animal drug research. Therefore, small animal SPECT is widely used in the research of novel drugs and is frequently used for the detection and research of laboratory animals (especially various sizes of laboratory mice).

[0004] Meanwhile, CT and PET scans are also widely used in laboratory animals and are common methods for their testing and analysis. These scans each have their own focus, complementing and being indispensable in laboratory animal testing. Building upon this, we are also considering providing equipment that combines SPECT with CT and PET scans, thus enabling the quickest and most convenient way to obtain meaningful test results from laboratory animals.

[0005] However, our analysis of existing technologies revealed that while there are combined devices (such as CN101848679A), these devices merely combine two detection methods. The specific application of these two detection methods still requires individual settings and adjustments. Moreover, this combination is not a combination of SPECT, CT, and PET.

[0006] Combining these two devices directly into one instrument does not reduce the workload of operation, nor does it effectively reduce the number of instrument accessories or the space occupied by the instrument. It is merely a combination without effectively forming a unified device.

[0007] There is a practical problem here: CT or SPECT scanners for laboratory animals can actually be made smaller, and given the small size of laboratory animals, there is potential to make combined systems easier to operate and more space-efficient. However, current technology does not offer this clear insight. Furthermore, current technology lacks a device that combines SPECT, CT, and PET.

[0008] With CN101848679A Figure 3 It can be seen that the so-called SPECT-CT combination actually combines SPECT-CT equipment based on the same detection object (the same region of interest). In this way, both devices function independently, and the position of each detection device needs to be adjusted to meet the measurement requirements for each measurement: "Locking the detector in the working position during CT acquisition and locking it in the stowed position when not performing CT acquisition (e.g., during nuclear image data acquisition or when the system is not in use)," and "Locking the X-ray detector in the appropriate position (e.g., in its working position opposite the X-ray source) during CT acquisition. Once CT acquisition is complete, fold the X-ray source to avoid obstruction and fold the X-ray detector and lock it in the stowed position, so that nuclear imaging data acquisition can begin (paragraph 66 of the instruction manual)." It is evident that the so-called SPECT-CT combination in the existing technology has not overcome the problems of cumbersome operation and easy mutual interference caused by using the two devices together. The "combined instrument" is cumbersome and difficult to use, with many defects.

[0009] In other words, one of the problems with current SPECT-CT combination instruments is that they haven't made effective improvements in terms of ease of use and avoiding conflicts when used together. The combination simply involves assembling components from the two devices, leading to numerous problems in their operation. Furthermore, there are no devices specifically designed for combining SPECT, CT, and PET.

[0010] In terms of testing for laboratory animals, PET is one of the most commonly used tests. However, it is difficult to combine PET devices with SPECT-CT. Setting up the three instruments separately would be a waste of funds, money, and space.

[0011] Existing technologies include devices that combine these three types of detection, but they are mostly "foolproof" combinations. While called combinations, they are in reality separate, requiring all necessary components, fixing mechanisms, and movement devices. Forcing them together creates the risk of collisions during movement. This redundant combination does not actually simplify cost or operation; it's simply a combination for the sake of combination.

[0012] This raises a real question: how to combine SPECT, CT, and PET into a single device that saves space and materials, and can perform the three tests in a simple, error-free, and collision-free manner? This requires thought and practical innovation. Summary of the Invention

[0013] The purpose of this invention is to provide a device that primarily addresses the issue of compactness and ease of use in SPECT-CT-PET combined devices. The device of this application, through its ingenious design, allows a single SPECT-CT-PET combined device to perform the most commonly used CT, SPECT, and PET detection modes with extremely simple and conflict-free operation. This simplifies common detection methods for laboratory animals and provides rapid results. This is achieved by mounting the X-ray source and flat panel detector in a vertically moving module, and by switching between SPECT and CT modes horizontally or vertically. Traditional combined devices require complex adjustments and alignment when adjusting the detection posture; this application completely avoids these complex operations. The entire device requires only two translation motors to switch between the three detection modes. Furthermore, through its simple structural design, this application allows for one-step integration with PET, sharing a single experimental subject moving device and a single slide stage to complete all three detections, greatly simplifying operational requirements.

[0014] To achieve the above objectives, the present invention provides the following technical solution: a SPECT and PET translational switching CT combined imaging device, characterized in that: it includes a fixed part 1, an object bed 2, a PET-SPECT device 3, a front plate 4, a CT device 5, and a rear plate 6.

[0015] The fixed components include a front base 11, a rear base 12, and an object bed 13. The object bed is fixed to the front base. The rear side of the front base and the front side of the rear base are spliced ​​and fixed together.

[0016] The object bed includes a slide table 21, a support device 22, and a bed body 23. The bed body is slidably fixed on the support device, the support device is slidably mounted on the slide table, and the slide table is fixed on the object bed base.

[0017] The PET-SPECT unit is mounted on a horizontal double guide rail 41 on the front side of the front plate. The CT unit is mounted between the rotary drive device 42 on the rear side of the front plate and the rear bearing 61 on the rear plate. The front plate is vertically fixed to the rear base by the front plate seat 43, and the rear plate is vertically fixed to the rear base by the rear plate seat 62.

[0018] The PET-SPECT device includes a main plate 31, a SPECT plate 32, a SPECT device 33, a PET plate 34, and a PET device 35. The SPECT device includes two opposing SPECT detectors 331 mounted on the front surface of the SPECT plate. The PET device includes an even number of circumferentially distributed PET detectors 351 mounted on the front surface of the PET plate. The SPECT plate 32 has a first hole 321 in the center, and the PET plate has a second hole 341 in the center. The SPECT plate and PET plate are mounted on the left and right sides of the front of the main plate, respectively, and can rotate independently. The main plate is slidably mounted in front of horizontal double guide rails.

[0019] Furthermore, the CT device includes an inner frame 51, an outer frame 52, a linear module 53, a motor 54, a radiation source 55, and a CT detector 56. The front side of the outer frame is a backplate 521. The linear module and motor are mounted on the rear side of the backplate. The inner frame is slidably fixed in a groove within the linear module, which is driven by the motor. The radiation source is fixed to the lower part of the inner frame, and the CT detector is fixed to the upper part of the inner frame. The backplate is fixed to a rotary drive device, which has a third hole 421 in the middle. The rear H-shaped surface of the outer frame is fixed to a rear bearing.

[0020] The bed has an end 231 for bearing loads.

[0021] A method for combined SPECT and PET translational switching CT imaging, implemented using the aforementioned combined SPECT and PET translational switching CT imaging device, is characterized by the following steps: 1) Preparation step: Powering on the combined imaging device to test the translation of the bed, main plate, and inner frame, as well as the rotation of the SPECT plate, PET plate, and CT device, confirming the data transmission, and proceeding to step 2.

[0022] 2) Select test procedure: Choose the test to perform first between PET and SPECT tests.

[0023] If performing a PET test first, move the main plate until the object bed, second hole, and third hole are coaxial, move the end of the bed into the PET device, perform the test, and transmit and collect the data. Then perform a SPECT test, moving the main plate until the object bed, first hole, and third hole are coaxial, moving the end of the bed into the SPECT device, performing the test, and transmitting and collecting the data.

[0024] If performing SPECT testing first, translate the main plate until the object bed, first hole, and third hole are coaxial. Move the end of the bed into the SPECT device, perform the test, and transmit and collect the data. Then perform PET testing, translating the main plate until the object bed, second hole, and third hole are coaxial. Move the end of the bed into the PET device, perform the test, and transmit and collect the data. After testing, proceed to step 3.

[0025] 3) CT scan procedure: The inner frame is moved up and down by a motor until it reaches one of the preset CT scan positions. The end of the bed is moved into the CT device to perform the CT scan, and the data is transmitted and collected. The bed is then removed.

[0026] A combined SPECT and PET translational CT imaging device includes a fixed part 1, an object bed 2, a PET-SPECT device 3, a front plate 4, a CT device 5, and a rear plate 6.

[0027] The fixed components include a front base 11, a rear base 12, and an object bed 13. The object bed is fixed to the front base. The rear side of the front base and the front side of the rear base are spliced ​​and fixed together.

[0028] The object bed includes a slide table 21, a support device 22, and a bed body 23. The bed body is slidably fixed on the support device, the support device is slidably mounted on the slide table, and the slide table is fixed on the object bed base.

[0029] The PET-SPECT unit is mounted on the vertical double guide rails 41 on the front side of the front plate. The CT unit is mounted between the rotary drive device 42 on the rear side of the front plate and the rear bearing 61 on the rear plate. The front plate is vertically fixed to the rear base by the front plate seat 43, and the rear plate is vertically fixed to the rear base by the rear plate seat 62.

[0030] The PET-SPECT device includes a main plate 31, a SPECT plate 32, a SPECT device 33, a PET plate 34, and a PET device 35. The SPECT device includes two opposing SPECT detectors 331 mounted on the front surface of the SPECT plate. The PET device includes an even number of circumferentially distributed PET detectors 351 mounted on the front surface of the PET plate. The SPECT plate 32 has a first hole 321 in the center, and the PET plate has a second hole 341 in the center. The SPECT plate and PET plate are mounted on the front side of the main plate, respectively, and can rotate independently. The main plate is slidably mounted in front of vertical double guide rails.

[0031] Furthermore, the CT device includes an inner frame 51, an outer frame 52, a linear module 53, a motor 54, a radiation source 55, and a CT detector 56. The front side of the outer frame is a backplate 521. The linear module and motor are mounted on the rear side of the backplate. The inner frame is slidably fixed in a groove within the linear module, which is driven by the motor. The radiation source is fixed to the lower part of the inner frame, and the CT detector is fixed to the upper part of the inner frame. The backplate is fixed to a rotary drive device, which has a third hole 421 in the middle. The rear H-shaped surface of the outer frame is fixed to a rear bearing.

[0032] The bed has an end 231 for bearing loads.

[0033] A method for combined SPECT and PET translational switching CT imaging, implemented using the aforementioned combined SPECT and PET translational switching CT imaging device, is characterized by the following steps: 1) Preparation step: Powering on the combined imaging device to test the translation of the bed, main plate, and inner frame, as well as the rotation of the SPECT plate, PET plate, and CT device, confirming the data transmission, and proceeding to step 2.

[0034] 2) Select test procedure: Choose the test to perform first between PET and SPECT tests.

[0035] If performing a PET test first, move the main plate until the object bed, second hole, and third hole are coaxial, move the end of the bed into the PET device, perform the test, and transmit and collect the data. Then perform a SPECT test, moving the main plate until the object bed, first hole, and third hole are coaxial, moving the end of the bed into the SPECT device, performing the test, and transmitting and collecting the data.

[0036] If performing SPECT testing first, translate the main plate until the object bed, first hole, and third hole are coaxial. Move the end of the bed into the SPECT device, perform the test, and transmit and collect the data. Then perform PET testing, translating the main plate until the object bed, second hole, and third hole are coaxial. Move the end of the bed into the PET device, perform the test, and transmit and collect the data. After testing, proceed to step 3.

[0037] 3) CT scan procedure: The inner frame is moved up and down by a motor until it reaches one of the preset CT scan positions. The end of the bed is moved into the CT device to perform the CT scan, and the data is transmitted and collected. The bed is then removed.

[0038] Compared to existing technologies, this application has several non-obvious advantages: First, while some existing technologies combine SPECT and CT or PET and CT, such combinations do not necessarily mean the device is very simple. In fact, the circuitry and components are still quite complex. This application not only combines all three but also makes the overall device extremely simple. How simple? Firstly, it only requires one object bed, completely eliminating the need for the separate detection beds / plates typically used in combination. The actual detection positions are all coaxial; the SPECT or translated PET and CT detection positions move, but the main detection axis remains stationary, and the experimental object only moves axially. Secondly, it further simplifies the movement methods in existing technologies. Through ingenious design, the movement method of the SPECT-CT-PET combination is extremely simple to operate. In the most common existing technologies, the four components—the SPECT detectors on both sides, the CT detector, and the X-ray source—must move independently. This requires at least four motors and four sets of guide rails, making the device not only complex but also inevitably increasing the risk of collisions between components. The configuration of this application allows the X-ray source and CT detector to move together. Adjustment of the CT detector requires only one motor, while the SPECT and PET detectors only require one motor for left-right switching. This simplifies the process to just two motors for adjusting all three detection methods. Thirdly, it virtually eliminates the risk of component collisions. For example, in existing combined equipment (such as CN101848679A), the CT detector, source, and SPECT detector are not specifically described; they are all adjusted and moved separately. This is not only cumbersome to adjust and align, but also difficult to operate, and carries the risk of component collisions. With this application, as long as the position is confirmed after movement, there is no risk of collision. There is no actual risk of collision between the devices themselves, or between the CT, PET, and SPECT devices. Fourth, the components are extremely simple. The SPECT and PET detectors on both sides require two motors, while the X-ray source and CT detector each use one motor. In practice, at least four motors would be needed. This application achieves this by switching between SPECT and PET scans with a single motor, handling both detection apertures. The CT detector, due to its ingenious design, requires only one motor to change the position of the X-ray source and CT detector relative to the detection position, thus enabling adjustments to at least two different detection positions. This adjustment is not only simple but also completely eliminates the risk of component collisions. Operators can complete the adjustment with a single button press based on system prompts—it's incredibly simple. Fifth, operation is extremely simple. With the single electrode automatically controlled (e.g., by a PLC controller), simply press a button to reset, and then, based on the system's stored position, press a button to control the motor movement device to reach the CT small FOV scanning position, the CT large FOV scanning position, and the SPECT and PET detection positions. Attached Figure Description

[0039] Figure 1 This is a schematic diagram of the upper side of the combined imaging device.

[0040] Figure 2 Right view of the combined imaging device.

[0041] Figure 3 This is a front view of the combined imaging device.

[0042] Figure 4 This is a partial disassembly view of the CT scan.

[0043] Figure 5 This is a view of the CT section before it was disassembled.

[0044] Reference numerals: 1. Fixed part; 2. Object bed; 3. PET-SPECT device; 4. Front plate; 5. CT device; 6. Rear plate; 11. Front base; 12. Rear base; 13. Object bed seat; 21. Slide table; 22. Support device; 23. Bed body; 231. End; 31. Main plate; 32. SPECT plate; 33. SPECT device; 34. PET plate; 35. SPECT device; 321. First hole; 331. SPECT detector; 341. Second hole; 351. PET detector; 41. Horizontal double guide rail; 42. Drive device; 43. Front plate seat; 421. Third hole; 51. Inner frame; 52. Outer frame; 53. Linear module; 54. Motor; 55. X-ray source; 56. CT detector; 521. Back plate; 61. Rear bearing; 62. Rear plate seat. Detailed Implementation

[0045] The technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention. The simplified posture adjustment of the integrated SPECT-CT-PET imaging device in this application is groundbreaking. The examples given should not be considered as necessary limitations on this application, such as the value of the field of view (FOV). Example

[0046] A combined SPECT and PET translational CT imaging device, characterized in that it includes a fixed part 1, an object bed 2, a PET-SPECT device 3, a front plate 4, a CT device 5, and a rear plate 6.

[0047] The combined imaging system is housed on a single fixed platform, with only one moving stage and coaxial detection positions. The CT scanner only requires a single motor to adjust the positions of the X-ray source and the lower CT detector, enabling multiple detections of a single object. Similarly, the PET-SPECT scanner only needs a single motor for lateral translation.

[0048] The fixed components include a front base 11, a rear base 12, and an object bed 13. The object bed is fixed to the front base. The rear side of the front base and the front side of the rear base are spliced ​​and fixed together. Typically, because the rear base needs to support the CT device that needs to move up and down, its height is lower than that of the front base. The object bed is specifically designed to support the object bed that needs to be moved.

[0049] The object bed includes a slide table 21, a support device 22, and a bed body 23. The bed body is slidably fixed on the support device, which is slidably mounted on the slide table, and the slide table is fixed on the object bed base. The bed body has a small cross-section to facilitate inspection; the most common design is a circular cross-section, but a partial circle or a partial ellipse is also possible.

[0050] The PET-SPECT unit is mounted on horizontal double guide rails 41 on the front side of the front panel. The CT unit is mounted between the rotary drive device 42 on the rear side of the front panel and the rear bearing 61 on the rear panel. The front panel is vertically fixed to the rear base by the front panel seat 43, and the rear panel is vertically fixed to the rear base by the rear panel seat 62. While the CT unit can be considered to be mounted between the front and rear panels, due to the need for rotation, it is actually mounted between the rotary drive device 42 and the rear bearing 61 on the rear panel. The entire frame is rotatable.

[0051] The PET-SPECT device includes a main plate 31, a SPECT plate 32, a SPECT device 33, a PET plate 34, and a PET device 35. The SPECT device includes two opposing SPECT detectors 331 mounted on the front surface of the SPECT plate. The PET device includes an even number of circumferentially distributed PET detectors 351 mounted on the front surface of the PET plate. The SPECT plate 32 has a first hole 321 in the center, and the PET plate has a second hole 341 in the center. The SPECT plate and PET plate are mounted on the left and right sides of the main plate, respectively, and can rotate independently. The main plate is slidably mounted in front of horizontal double guide rails. The number of PET detectors is, for example, 6 / 8 / 10, and the number of SPECT detectors is two on the left and right sides. The SPECT plate and PET plate can be common geometric shapes, such as regular polygons, with circles being the most common. During switching, the device can be moved horizontally to align the first or second hole with the object bed. The object bed is placed in the detection area, enabling rotational detection, or CT detection can be performed through the first or second hole.

[0052] Furthermore, the CT device includes an inner frame 51, an outer frame 52, a linear module 53, a motor 54, a radiation source 55, and a CT detector 56. The front of the outer frame is a backplate 521, and the linear module and motor are mounted on the rear side of the backplate. The inner frame is slidably fixed in the slide groove of the linear module, which is driven by the motor. The radiation source is fixed to the lower part of the inner frame, and the CT detector is fixed to the upper part of the inner frame. The backplate is fixed to a rotary drive device, which has a third hole 421 in the middle. The rear H-shaped surface of the outer frame is fixed to a rear bearing. Thus, after the motor drives the linear module, the distance between the radiation source and the CT detector and the object changes, facilitating detection positions corresponding to different FOVs, such as large, medium, and small FOVs. The entire CT device is rotatable.

[0053] The bed has end 231 for load-bearing. The bed can be made of a variety of strong non-metallic materials. Example

[0054] For the apparatus of Embodiment 1, detection can be performed selectively at either the PET scan location or the SPECT scan location, or selectively at either the CT large FOV scan location or the CT small FOV scan location. This demonstrates the advantage of the apparatus of this application, enabling three types of detection for a single object with minimal operations.

[0055] A method for combined SPECT and PET translational switching CT imaging, implemented using the aforementioned combined SPECT and PET translational switching CT imaging device, is characterized by the following steps: 1) Preparation step: Powering on the combined imaging device to test the translation of the bed, main plate, and inner frame, as well as the rotation of the SPECT plate, PET plate, and CT device, confirming the data transmission, and proceeding to step 2.

[0056] 2) Select test procedure: Choose the test to perform first between PET and SPECT tests.

[0057] If performing a PET test first, move the main plate until the object bed, second hole, and third hole are coaxial, move the end of the bed into the PET device, perform the test, and transmit and collect the data. Then perform a SPECT test, moving the main plate until the object bed, first hole, and third hole are coaxial, moving the end of the bed into the SPECT device, performing the test, and transmitting and collecting the data.

[0058] If performing SPECT testing first, translate the main plate until the object bed, first hole, and third hole are coaxial. Move the end of the bed into the SPECT device, perform the test, and transmit and collect the data. Then perform PET testing, translating the main plate until the object bed, second hole, and third hole are coaxial. Move the end of the bed into the PET device, perform the test, and transmit and collect the data. After testing, proceed to step 3.

[0059] This embodiment can also be modified to perform both PET and SPECT detection.

[0060] 3) CT Scanning Procedure: The inner frame is moved up and down by a motor until it reaches one of the preset CT scan positions. The end of the bed is moved into the CT unit for CT scanning, and data is transmitted and collected. The bed is then removed. CT scanning can be performed at either the large FOV or small FOV scanning position, and adjustments are made before entering the target area. Example

[0061] A combined SPECT and PET translational CT imaging device includes a fixed part 1, an object bed 2, a PET-SPECT device 3, a front plate 4, a CT device 5, and a rear plate 6.

[0062] The combined imaging system is housed entirely on a fixed platform, with only one moving stage and coaxial detection positions. The CT scanner only requires a single motor to adjust the positions of the X-ray source and the lower CT detector, enabling multiple detections of a single object. Similarly, the PET-SPECT scanner only needs a single motor for vertical, horizontal, and lateral movement.

[0063] The fixed components include a front base 11, a rear base 12, and an object bed 13. The object bed is fixed to the front base. The rear side of the front base and the front side of the rear base are spliced ​​and fixed together. Typically, because the rear base needs to support the CT device that needs to move up and down, its height is lower than that of the front base. The object bed is specifically designed to support the object bed that needs to be moved.

[0064] The object bed includes a slide table 21, a support device 22, and a bed body 23. The bed body is slidably fixed on the support device, which is slidably mounted on the slide table, and the slide table is fixed on the object bed base. The bed body has a small cross-section to facilitate inspection; the most common design is a circular cross-section, but a partial circle or a partial ellipse is also possible.

[0065] The PET-SPECT unit is mounted on vertical double guide rails 41 on the front side of the front panel. The CT unit is mounted between the rotary drive device 42 on the rear side of the front panel and the rear bearing 61 on the rear panel. The front panel is vertically fixed to the rear base by the front panel seat 43, and the rear panel is vertically fixed to the rear base by the rear panel seat 62. While the CT unit can be considered to be mounted between the front and rear panels, due to the need for rotation, it is actually mounted between the rotary drive device 42 and the rear bearing 61 on the rear panel. The entire frame is rotatable.

[0066] The PET-SPECT device includes a main plate 31, a SPECT plate 32, a SPECT device 33, a PET plate 34, and a PET device 35. The SPECT device includes two opposing SPECT detectors 331 mounted on the front surface of the SPECT plate. The PET device includes an even number of circumferentially distributed PET detectors 351 mounted on the front surface of the PET plate. The SPECT plate 32 has a first hole 321 in the center, and the PET plate has a second hole 341 in the center. The SPECT plate and PET plate are mounted vertically on the front side of the main plate and can rotate independently. The main plate is slidably mounted in front of vertical double guide rails. The number of PET detectors is, for example, 6 / 8 / 10, and the number of SPECT detectors is two on the left and right. The SPECT plate and PET plate can be common geometric shapes, such as regular polygons, with circles being the most common. During switching, they can be moved up and down to align the first or second hole with the object bed. The object bed is placed in the detection area, enabling rotational detection, or allowing CT scans to be performed through the first or second hole.

[0067] Furthermore, the CT device includes an inner frame 51, an outer frame 52, a linear module 53, a motor 54, a radiation source 55, and a CT detector 56. The front of the outer frame is a backplate 521, and the linear module and motor are mounted on the rear side of the backplate. The inner frame is slidably fixed in the slide groove of the linear module, which is driven by the motor. The radiation source is fixed to the lower part of the inner frame, and the CT detector is fixed to the upper part of the inner frame. The backplate is fixed to a rotary drive device, which has a third hole 421 in the middle. The rear H-shaped surface of the outer frame is fixed to a rear bearing. Thus, after the motor drives the linear module, the distance between the radiation source and the CT detector and the object changes, facilitating detection positions corresponding to different FOVs, such as large, medium, and small FOVs. The entire CT device is rotatable.

[0068] The bed has end 231 for load-bearing. The bed can be made of a variety of strong non-metallic materials. Example

[0069] For the apparatus of Embodiment 1, detection can be performed selectively at either the PET scan location or the SPECT scan location, or selectively at either the CT large FOV scan location or the CT small FOV scan location. This demonstrates the advantage of the apparatus of this application, enabling three types of detection for a single object with minimal operations.

[0070] A method for combined SPECT and PET translational switching CT imaging, implemented using the aforementioned combined SPECT and PET translational switching CT imaging device, is characterized by the following steps: 1) Preparation step: Powering on the combined imaging device to test the translation of the bed, main plate, and inner frame, as well as the rotation of the SPECT plate, PET plate, and CT device, confirming the data transmission, and proceeding to step 2.

[0071] 2) Select test procedure: Choose the test to perform first between PET and SPECT tests.

[0072] If performing a PET test first, move the main plate until the object bed, second hole, and third hole are coaxial, move the end of the bed into the PET device, perform the test, and transmit and collect the data. Then perform a SPECT test, moving the main plate until the object bed, first hole, and third hole are coaxial, moving the end of the bed into the SPECT device, performing the test, and transmitting and collecting the data.

[0073] If SPECT testing is performed first, the main plate is moved until the object bed, first hole, and third hole are coaxial. The end of the bed is then moved into the SPECT device for testing, and the data is transmitted and collected. Next, PET testing is performed. The main plate is moved until the object bed, second hole, and third hole are coaxial. The end of the bed is then moved into the PET device for testing, and the data is transmitted and collected. After testing, proceed to step 3. This embodiment can also be modified to perform both PET and SPECT testing.

[0074] 3) CT Scanning Procedure: The inner frame is moved up and down by a motor until it reaches one of the preset CT scan positions. The end of the bed is moved into the CT unit for CT scanning, and data is transmitted and collected. The bed is then removed. CT scanning can be performed at either the large FOV or small FOV scanning position, and adjustments are made before entering the target area. Example

[0075] This section introduces the principles of this application. The main innovation lies in the SPECT-PET imaging device, which simplifies the operation of the combined device to the greatest extent possible. SPECT and CT share the same axial scanning space; motion control is simplified, reducing the number of motors from three or more to one. Typically, at least three motors are required: one for PET and one for each of the opposing SPECT detectors. This application only requires one motor. Movement can be left-right or up-down, as long as alignment is achieved.

[0076] Furthermore, based on the CT imaging device and its necessary rotation drive device, it is further integrated with PET and SPECT to form a device that integrates three detection methods, and the component layout and space utilization are extremely simple.

[0077] The X-ray source and flat panel detector in the CT of this application only require one motor on the linear module to drive the CT to adjust the FOV (field of view) and magnification.

[0078] First, the object bed enters the PET unit for PET testing. PET testing can be performed by rotating a PET plate; this is the first testing step. PET detectors can be 6 pairs, 8 pairs, 10 pairs, etc.

[0079] Furthermore, during SPECT scanning, the object bed is first withdrawn, then the main plate is moved left and right or up and down, and then the object bed is entered for SPECT detection. There is a rotation requirement here, meaning that both the PET plate and the SPECT plate can be rotated.

[0080] In a CT scan, the linear module moves the X-ray source downwards, which in turn moves the flat panel detector downwards synchronously. The X-ray source position can be adjusted according to the required FOV or magnification, allowing for large FOV, small FOV, or medium FOV scanning positions. The object bed is then moved in, and the CT scan begins. Example

[0081] The principles of this application will be explained below with reference to the accompanying drawings. As you can see, Figure 1 The image shows a top-side view of the overall device of this application. The PET and SPECT units require rotation, so they are both mounted on a single plate, which is then mounted on the main plate. For fixing the backplate, those skilled in the art can use common methods. In practice, the backplate is fixed to the rotation drive mechanism. After the main plate is moved into position, the object bed can be inserted for testing. PET and SPECT are selectively performed, but both can be performed if needed. The CT unit is located behind the front plate and is used in conjunction with the other two. All three testing methods share the same axial position; the object bed only needs to be moved back and forth to switch between testing methods.

[0082] Figure 2 The image shows the adjustment of the PET-SPECT unit position in this device, meaning that the PET and SPECT units can be switched between use as the main plate moves. Both units can rotate independently.

[0083] Figure 3 The middle view is a side view of the device, which clearly shows that the CT device is mounted between the front and rear plates, between the rotating device and the rear bearing, and can rotate. At the same time, the inner frame can move up and down under the drive of the linear module, meaning that CT detection can switch between multiple detection positions with different FOVs. The entire outer frame can rotate.

[0084] Figure 4 , Figure 5 The internal structure of the CT scanner can be seen, as well as the fit between the inner and outer frames.

[0085] This application also requires the connection of many power lines and signal lines, which can be installed using conventional methods in the field and are not the focus of the inventive concept.

[0086] The above descriptions are merely embodiments of the present invention, and common knowledge regarding specific structures and characteristics of the solutions is not described in detail here. It will be apparent to those skilled in the art that the present invention is not limited to the details of the above exemplary embodiments, and that the present invention can be implemented in other specific forms without departing from the spirit or essential characteristics of the invention. Therefore, the embodiments should be considered exemplary and non-limiting in all respects, and the scope of the present invention is defined by the appended claims rather than the foregoing description. Therefore, it is intended that all variations falling within the meaning and scope of equivalents of the claims be included within the present invention. No reference numerals in the claims should be construed as limiting the scope of the claims.

Claims

1. A combined SPECT and PET translational CT imaging device, characterized in that: Includes a fixed part (1), an object bed (2), a PET-SPECT device (3), a front plate (4), a CT device (5), and a rear plate (6); The fixed parts include a front base (11), a rear base (12), and an object bed (13); the object bed is fixed on the front base; the rear side of the front base and the front side of the rear base are spliced ​​and fixed. The object bed includes a slide (21), a support device (22), and a bed body (23); the bed body is slidably fixed on the support device, the support device is slidably mounted on the slide, and the slide is fixed on the object bed seat; The PET-SPECT device is mounted on the horizontal double guide rail (41) on the front side of the front plate; the CT device is mounted between the rotary drive device (42) on the rear side of the front plate and the rear bearing (61) on the rear plate; the front plate is vertically fixed to the rear base by the front plate seat (43), and the rear plate is vertically fixed to the rear base by the rear plate seat (62); The PET-SPECT device includes a main plate (31), a SPECT plate (32), a SPECT device (33), a PET plate (34), and a PET device (35); the SPECT device includes two opposing SPECT detectors (331) mounted on the front surface of the SPECT plate, and the PET device includes an even number of circumferentially distributed PET detectors (351) mounted on the front surface of the PET plate. The SPECT plate (32) has a first hole (321) in the middle, and the PET plate has a second hole (341) in the middle. The SPECT plate and the PET plate are mounted on the left and right sides of the main plate respectively, and can rotate independently; the main plate is slidably mounted in front of the horizontal double guide rails.

2. The SPECT and PET translation-switching CT combined imaging device as described in claim 1, characterized in that: The CT device includes an inner frame (51), an outer frame (52), a linear module (53), a motor (54), an X-ray source (55), and a CT detector (56); the front side of the outer frame is a back plate (521), the linear module and the motor are mounted on the rear side of the back plate, the inner frame is slidably fixed in the slide groove of the linear module, and the linear module is driven by the motor; the X-ray source is fixed at the lower part of the inner frame, and the CT detector is fixed at the upper part of the inner frame; The back plate is fixed on the rotary drive device, which has a third hole (421) in the middle; the rear H-shaped surface of the outer frame is fixed on the rear bearing. The bed has an end (231) for bearing.

3. A method for combined SPECT and PET translational CT imaging, implemented using the combined SPECT and PET translational CT imaging device as described in claim 1 or 2, characterized in that, Includes the following steps: Preparation steps: Power on the imaging device to test the translation of the bed, main plate, and inner frame, as well as the rotation of the SPECT plate, PET plate, and CT device. Confirm the data transmission and proceed to step 2. Select test procedure: Choose the test to perform first between PET and SPECT tests; If PET testing is performed first, the main plate is moved until the object bed, the second hole, and the third hole are coaxial. The end of the bed is then moved into the PET device for testing, and the data is transmitted back and collected. If SPECT testing is performed next, the main plate is moved until the object bed, the first hole, and the third hole are coaxial. The end of the bed is then moved into the SPECT device for testing, and the data is transmitted back and collected. If SPECT testing is performed first, the main plate is moved until the object bed, the first hole, and the third hole are coaxial. The end of the bed is then moved into the SPECT device for testing, and the data is transmitted back and collected. Next, perform PET testing. Move the main plate until the object bed, the second hole, and the third hole are coaxial. Move the end of the bed into the PET device, perform the test, and transmit and collect the data. After testing, proceed to step 3; CT scan procedure: The inner frame is moved up and down by a motor until it reaches one of the preset CT scan positions; the end of the bed is moved into the CT device for CT scan, data is transmitted and collected; the bed is then removed.

4. A combined SPECT and PET translational CT imaging device, characterized in that: Includes a fixed part (1), an object bed (2), a PET-SPECT device (3), a front plate (4), a CT device (5), and a rear plate (6); The fixed parts include a front base (11), a rear base (12), and an object bed (13); the object bed is fixed on the front base; the rear side of the front base and the front side of the rear base are spliced ​​and fixed. The object bed includes a slide (21), a support device (22), and a bed body (23); the bed body is slidably fixed on the support device, the support device is slidably mounted on the slide, and the slide is fixed on the object bed seat; The PET-SPECT device is mounted on the vertical double guide rail (41) on the front side of the front plate; the CT device is mounted between the rotary drive device (42) on the rear side of the front plate and the rear bearing (61) on the rear plate; the front plate is vertically fixed to the rear base by the front plate seat (43), and the rear plate is vertically fixed to the rear base by the rear plate seat (62). The PET-SPECT device includes a main plate (31), a SPECT plate (32), a SPECT device (33), a PET plate (34), and a PET device (35); the SPECT device includes two opposing SPECT detectors (331) mounted on the front surface of the SPECT plate, and the PET device includes an even number of circumferentially distributed PET detectors (351) mounted on the front surface of the PET plate. The SPECT plate (32) has a first hole (321) in the middle, and the PET plate has a second hole (341) in the middle. The SPECT plate and the PET plate are respectively mounted on the front side of the main plate and can rotate independently; the main plate is slidably mounted in front of the vertical double guide rails.

5. The SPECT and PET translation-switching CT combined imaging device as described in claim 4, characterized in that: The CT device includes an inner frame (51), an outer frame (52), a linear module (53), a motor (54), an X-ray source (55), and a CT detector (56); the front side of the outer frame is a back plate (521), the linear module and the motor are mounted on the rear side of the back plate, the inner frame is slidably fixed in the slide groove of the linear module, and the linear module is driven by the motor; the X-ray source is fixed at the lower part of the inner frame, and the CT detector is fixed at the upper part of the inner frame; The back plate is fixed on the rotary drive device, which has a third hole (421) in the middle; the rear H-shaped surface of the outer frame is fixed on the rear bearing. The bed has an end (231) for bearing.

6. A method for combined SPECT and PET translational CT imaging, implemented using the combined SPECT and PET translational CT imaging device as described in claim 4 or 5, characterized in that, Includes the following steps: Preparation steps: Power on the imaging device to test the translation of the bed, main plate, and inner frame, as well as the rotation of the SPECT plate, PET plate, and CT device. Confirm the data transmission and proceed to step 2. Select test procedure: Choose the test to perform first between PET and SPECT tests; If PET testing is performed first, the main plate is moved until the object bed, the second hole, and the third hole are coaxial. The end of the bed is then moved into the PET device for testing, and the data is transmitted back and collected. If SPECT testing is performed next, the main plate is moved until the object bed, the first hole, and the third hole are coaxial. The end of the bed is then moved into the SPECT device for testing, and the data is transmitted back and collected. If SPECT testing is performed first, the main plate is moved until the object bed, the first hole, and the third hole are coaxial. The end of the bed is then moved into the SPECT device for testing, and the data is transmitted back and collected. Next, perform PET testing. Move the main plate until the object bed, the second hole, and the third hole are coaxial. Move the end of the bed into the PET device, perform the test, and transmit and collect the data. After testing, proceed to step 3; CT scan procedure: The inner frame is moved up and down by a motor until it reaches one of the preset CT scan positions; the end of the bed is moved into the CT device for CT scan, data is transmitted and collected; the bed is then removed.

Images