Patient fixation device and positioning method for boron neutron capture therapy

Abstract

This invention discloses a patient fixation device and positioning method for boron neutron capture therapy, belonging to the field of surgical medical device technology. It includes a positioning plate, a head positioning plate, and a connector between the positioning plate and the head positioning plate. The two edges of the positioning plate taper inward at corresponding shoulder positions to form a shoulder avoidance structure. The patient fixation device also includes a posture monitoring unit and an adjustment data display unit. The posture monitoring unit is used to monitor the spatial position of the head positioning plate in real time. This invention forms a closed-loop control mechanism through the posture monitoring unit and the adjustment data display unit, monitoring the spatial pose of the head positioning plate in real time during treatment and automatically performing dynamic compensation when minute displacements occur, ensuring that the patient's target area is always accurately maintained in the preset treatment position. High-precision pose maintenance improves the accuracy of dose delivery, thereby comprehensively improving the treatment efficiency and clinical efficacy of boron neutron capture therapy.

Description

Technical Field

[0001] This invention relates to the field of surgical medical device technology, and in particular to a patient fixation device and positioning method for boron neutron capture therapy. Background Technology

[0002] Boron neutron capture therapy (BNCT), an internationally recognized cutting-edge radiotherapy technique, has a core advantage in its unique dose deposition mechanism: through targeted enrichment of boron drugs and precise neutron beam irradiation, the radiation dose is specifically deposited on tumor cells, thereby significantly reducing damage to surrounding normal tissues. This treatment is particularly suitable for glioblastoma and head and neck tumors, which together account for more than 80% of BNCT clinical cases.

[0003] During BNCT treatment, to ensure a sufficiently high neutron dose rate to the tumor target area and thus guarantee treatment efficiency, the patient's treatment site should be as close as possible to the exit port of the neutron therapy head. This is because the neutron dose rate decays rapidly in air, and an excessively large air gap between the treatment site and the exit port will directly lead to a decrease in the target dose rate, affecting the treatment outcome.

[0004] However, currently used BNCT patient fixation devices (such as carbon fiber fixation plates and head supports) generally suffer from geometrical fit defects. Traditional fixation devices typically employ square cross-section structures or rigid head frame designs, which can cause significant spatial interference during positioning procedures for brain and head and neck cancers. Specifically, when clinicians attempt to move the patient's tumor target area as close as possible to the treatment head outlet by moving the treatment bed, the safe distance between the edge of the patient fixation device and the treatment head assembly may shrink to a critical value, triggering the device's anti-collision interlock mechanism. This risk of mechanical interference necessitates the provision of a certain safe buffer distance during clinical operations, directly leading to two key issues: First, the beam irradiation angle is limited. Due to the mechanical interference of the head support frame, the rotation angle of the treatment bed is often limited to a narrow range of 180° to 360° in actual operation, resulting in insufficient selectable beam irradiation angles. This leads to a decrease in the conformity index of multi-field irradiation schemes, making it difficult to achieve optimal dose coverage of the tumor target area.

[0005] Secondly, the dosimetric characteristics deteriorate. As mentioned earlier, the neutron fluence rate decreases rapidly with increasing air path. The safety buffer distance that is forced to be reserved due to mechanical interference actually increases the transmission path of the neutron beam in the air, resulting in a significant decrease in the actual neutron fluence rate obtained in the tumor target area and a reduction in treatment efficiency.

[0006] Furthermore, traditional fixation devices have limited adjustment capabilities, making it difficult to flexibly adjust them according to the patient's body shape, tumor location, and treatment plan. When non-standard body positions (such as lateral neck flexion) are required for irradiation, existing devices often cannot provide sufficient degree of adjustment freedom, further limiting the optimization space for treatment plans.

[0007] Therefore, there is an urgent need to develop a patient fixation device that can effectively avoid mechanical interference, provide multi-degree-of-freedom adjustment functions, and maintain high-precision positioning during treatment, in order to meet the stringent requirements of BNCT for precise positioning. Summary of the Invention

[0008] The technical problem to be solved by the present invention is to overcome the shortcomings of the prior art and provide a patient fixation device and positioning method for boron neutron capture therapy, thereby solving the problems in the background art.

[0009] To achieve the above-mentioned objective, the first aspect of the present invention provides a patient fixation device for boron neutron capture therapy, comprising a body positioning plate, a head positioning plate, and a connector connecting the body positioning plate and the head positioning plate. The two sides of the body positioning plate taper inward at the corresponding shoulder positions to form a shoulder avoidance structure; The head positioning plate is equipped with a switchable supine position-specific component and a prone position-specific component. The connector is detachably connected to the body positioning plate and the head positioning plate, and has a longitudinal adjustment structure for adjusting the relative position of the head positioning plate in the longitudinal direction, a lateral adjustment structure for adjusting the relative position of the head positioning plate in the lateral direction, and an angle adjustment structure for adjusting the deflection angle of the head positioning plate relative to the body positioning plate. The patient fixation device also includes a posture monitoring unit and an adjustment data display unit. The posture monitoring unit is used to detect the spatial position of the head positioning plate in real time. The adjustment data display unit drives the longitudinal adjustment structure to dynamically compensate the position of the head positioning plate according to the deviation between the spatial position fed back by the posture monitoring unit and the preset target position. Both the lateral adjustment structure and the angle adjustment structure are manually adjustable through the cooperation of the positioning pin and the positioning hole.

[0010] Optionally, the attitude monitoring unit includes a plurality of optical markers disposed on the head positioning plate, and an optical tracking camera that cooperates with the optical markers.

[0011] Optionally, the attitude monitoring unit includes an inertial measurement unit disposed on the head positioning plate, the inertial measurement unit being used to collect acceleration signals and angular velocity signals of the head positioning plate.

[0012] Optionally, the adjustment data display unit (19) includes an alarm for displaying alarm signals.

[0013] Optionally, the head positioning plate can be switched to the supine position-specific component or the prone position-specific component via a quick-release interface.

[0014] Optionally, the longitudinal adjustment structure includes a first positioning groove provided along the width direction of the body positioning plate, and a third positioning post provided on the connector. The third positioning post is selectively locked at different positions of the first positioning groove to realize the longitudinal manual adjustment of the head positioning plate. The lateral adjustment structure includes a plurality of third positioning holes arranged laterally on the connector, and the third positioning post is disposed on the body positioning plate. The third positioning post is selectively locked into different third positioning holes to realize the lateral manual adjustment of the head positioning plate.

[0015] Optionally, the angle adjustment structure includes a first positioning hole and a second positioning hole disposed on the connector, and a first positioning post and a second positioning post disposed on the head positioning plate; The first positioning post and the first positioning hole form a rotation axis, and the second positioning post is selectively locked with one of the second positioning holes to lock the deflection angle of the head positioning plate and realize manual angle adjustment.

[0016] Optionally, the two sides of the body positioning plate are also provided with an array of fixing holes for mounting auxiliary grips.

[0017] Optionally, the positioning plate is further provided with a second positioning groove and positioning hole for docking and locking with a CT bed or treatment bed.

[0018] A second aspect of the present invention provides a method for positioning a patient fixation device for boron neutron capture therapy, comprising the following steps: S1: Based on the patient's imaging data, determine the direction and angle of the patient's neck lateral flexion, and determine the initial positioning hole selection parameters of the patient fixation device as described above, as well as the rotation angle and position of the treatment bed, and pre-position the patient; S2: In the simulation positioning room, according to the parameters determined in S1, the longitudinal and lateral positions and deflection angles of the head positioning plate relative to the body positioning fixation plate are adjusted through the connector, the patient is fixed on the patient fixation device, the positioning parameters are recorded, and the current spatial position of the head positioning plate is set as the preset target position. S3: In the pre-positioning room, the patient's position is reproduced according to the positioning parameters recorded in S2. The positioning is verified and corrected through the image guidance system. The optimal rotation angle and position of the treatment bed are determined according to the relative position of the patient's treatment site and the outlet of the treatment head. S4: After the patient enters the treatment room, the treatment bed is adjusted according to the determined optimal rotation angle and position, and the patient's position is reproduced through the patient fixation device according to the positioning parameters recorded in S2. S5: During the treatment, the spatial position of the head positioning plate is detected in real time by the posture monitoring unit. When the deviation between the detected value and the preset target position exceeds the threshold, the position of the head positioning plate is dynamically compensated by manually adjusting the longitudinal adjustment structure.

[0019] The beneficial effects of this invention are: 1. The patient fixation device and positioning method for boron neutron capture therapy of the present invention significantly improves treatment accuracy and safety through the synergistic effect of multi-dimensional structural optimization and automated compensation. Specifically, the shoulder avoidance structure design of the positioning plate effectively reduces the risk of mechanical interference between the device and the treatment head assembly, providing a larger rotation angle space for the treatment bed; the switchable supine / prone position dedicated component meets the positioning requirements of different indications and treatment plans; the longitudinal, lateral, and angle adjustment structure integrated with the connectors achieves precise positioning and flexible adjustment of the patient's head and neck; furthermore, the introduction of a posture monitoring unit and an adjustment data display unit forms a closed-loop control mechanism, which monitors the spatial posture of the head positioning plate in real time during treatment and automatically performs dynamic compensation when minor displacement occurs, ensuring that the patient's target area is always accurately maintained in the preset treatment position. The synergistic cooperation of the above structural features and automated control mechanism fundamentally solves the problem of beam angle limitation caused by mechanical interference in the prior art, while improving the accuracy of dose delivery through high-precision posture maintenance, thereby comprehensively improving the treatment efficiency and clinical efficacy of boron neutron capture therapy.

[0020] 2. The patient fixation device and positioning method for boron neutron capture therapy of the present invention employs a narrow-body design for the positioning fixation plate, with its shoulder area tapering inward to form a clearance structure. Simultaneously, the head positioning plate utilizes a minimal projected area design with streamlined edges, smooth and without sharp protrusions. This significantly reduces the width and protruding contours of the support device, greatly decreasing the probability of collision between the fixation device and the treatment head assembly during treatment bed rotation. In clinical operation, the treatment bed can rotate at a wider angle (even a full 360° rotation), providing greater freedom in developing multi-field irradiation plans and improving target dose conformity.

[0021] 3. The patient fixation device and positioning method for boron neutron capture therapy of the present invention employs detachable connections between the connector and the body positioning plate, as well as between the connector and the head positioning plate. Through the cooperation of positioning grooves, positioning holes, and positioning posts, the longitudinal and lateral positions, as well as the deflection angle, of the head positioning plate are adjusted. This multi-dimensional adjustment structure can adapt to patients of different body types and head and neck sizes, while also supporting non-standard positions such as lateral neck flexion, further expanding the selectable beam directions. Furthermore, the head positioning plate uses a quick-release interface to achieve rapid switching between supine and prone positions, facilitating operation and improving clinical efficiency. Combined with the use of an auxiliary grip and a head fixation membrane, the accuracy and repeatability of patient positioning can be significantly improved.

[0022] 4. The patient fixation device and positioning method for boron neutron capture therapy of the present invention uses thin carbon fiber material for the supine and prone positions. This material has the characteristics of high specific strength and low X-ray attenuation coefficient, which minimizes interference with image positioning and reduces the physical projection area while ensuring sufficient structural rigidity, further reducing the risk of interference. Simultaneously, the dedicated components are equipped with a headrest, which can be made of memory foam or moldable material to adapt to the patient's head and neck contours, significantly improving patient comfort during prolonged treatment.

[0023] 5. The patient fixation device and positioning method for boron neutron capture therapy of the present invention can detect the spatial position of the head positioning plate in real time through a posture monitoring unit (optical markers and tracking cameras or inertial measurement units) and an adjustment data display unit (including an alarm). When the deviation between the detected value and the preset target position exceeds a threshold, the alarm sounds and visually, prompting the operator to intervene manually in a timely manner and perform dynamic compensation by manually adjusting the longitudinal adjustment structure. This mechanism effectively overcomes the shortcomings of traditional fixation devices in sensing and correcting minute patient displacements without the need for complex electric actuators, ensuring the consistency of target area positioning throughout the treatment process. Attached Figure Description

[0024] Figure 1 This is a schematic diagram of the overall structure of the patient fixation device and positioning method for boron neutron capture therapy according to the present invention; Figure 2 This is a schematic diagram of the structure between the head positioning plate, the connector, and the body positioning plate of the patient fixation device and positioning method for boron neutron capture therapy according to the present invention. Figure 3 This is a schematic diagram of the head positioning plate structure of the patient fixation device and positioning method for boron neutron capture therapy according to the present invention; Figure 4 This is a schematic diagram of the connecting component structure of the patient fixation device and positioning method for boron neutron capture therapy according to the present invention; Figure 5 This is a schematic diagram of the patient fixation plate structure of the patient fixation device and positioning method for boron neutron capture therapy according to the present invention; Figure 6 This is a cross-sectional schematic diagram of the patient fixation plate of the patient fixation device and positioning method for boron neutron capture therapy according to the present invention; Figure 7 This is a schematic diagram illustrating the positioning steps of the patient fixation device for boron neutron capture therapy according to the present invention.

[0025] Explanation of reference numerals in the attached figures: 1. Head positioning plate; 2. Fixing hole; 3. First positioning post; 4. Second positioning post; 5. Connector; 6. First positioning hole; 7. Second positioning hole; 8. Third positioning post; 9. Body positioning plate; 10. First positioning groove; 11. Third positioning hole; 12. Handle socket; 13. Second positioning groove; 14. Positioning hole; 15. Attitude monitoring unit; 17. Optical tracking camera; 18. Inertial measurement unit; 19. Adjustment data display unit; 21. Limit switch; 22. Emergency stop button.

[0026] The realization of the objective, functional features and advantages of the present invention will be further explained in conjunction with the embodiments and with reference to the accompanying drawings. Detailed Implementation

[0027] It should be understood that the specific embodiments described herein are merely illustrative of the invention and are not intended to limit the invention.

[0028] In the description of this invention, it should be noted that, unless otherwise explicitly specified and limited, the terms "installation," "connection," and "joining" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral connection; they can refer to a mechanical connection, a direct connection, or an indirect connection through an intermediate medium; they can refer to the internal communication of two components or the interaction between two components. Those skilled in the art can understand the specific meaning of the above terms in this invention according to the specific circumstances.

[0029] Reference Figures 1-6 This embodiment provides a patient fixation device for boron neutron capture therapy. The device mainly includes a positioning fixation plate 9 for supporting the patient's body, a head positioning plate 1 for fixing the patient's head and neck, and a connector 5 for connecting the positioning fixation plate 9 and the head positioning plate 1. The device adopts a modular design to address the problems of limited beam angle and deteriorated dosimetric characteristics caused by mechanical interference in existing fixation devices during treatment.

[0030] To minimize physical interference with the movement of the treatment head and allow the patient's target area to be closer to the neutron beam exit, this embodiment features optimized design of key components. Specifically, such as... Figure 2 and Figure 5 As shown, the two side edges of the positioning plate 9 taper inward at the corresponding shoulder positions, forming a shoulder avoidance structure. The narrow-body design significantly reduces the width of the device in the shoulder region. Simultaneously, the shoulder corners of the positioning plate 9 and the edges of the head positioning plate 1 are streamlined, smooth, and without sharp protrusions. When the treatment bed rotates to seek the optimal irradiation angle, it effectively reduces the risk of collision between the device and the treatment head assembly, thereby allowing the treatment bed to operate within a wider angular range (e.g., achieving full 360° rotation). This provides greater freedom in developing multi-field irradiation plans and effectively improves target conformity.

[0031] On the other hand, to meet the treatment needs of patients with glioblastoma and head and neck tumors in different body positions (supine and prone), the head positioning plate 1 adopts a dual-mode adaptation design. The head positioning plate 1 is equipped with a quick-switchable supine and prone position dedicated component, which are connected via a quick-release interface. Both dedicated components are made of thin carbon fiber material, which has high specific strength and low X-ray attenuation coefficient. While ensuring sufficient rigidity, it minimizes interference with image positioning and reduces the physical projection area, further reducing the risk of interference with the treatment head component. Each dedicated component is equipped with a correspondingly shaped headrest, which can be made of memory foam or moldable material to adapt to the patient's head and neck contour, improving patient comfort during prolonged treatment. The component edge also has fixing holes 2 for rigidly fixing the patient's head with a head fixation membrane. Specifically, the fixation membrane edge has buckles that form a quick-locking structure with the fixing holes 2, achieving stable fixation.

[0032] To accurately and comfortably position the patient's head in the desired treatment position, connector 5 provides multi-degree-of-freedom adjustment. Connector 5 is detachably connected to both the positioning fixation plate 9 and the head positioning plate 1, and integrates longitudinal, lateral, and angle adjustment structures. The lateral and angle adjustment structures are manually adjustable via the engagement of positioning posts and positioning holes.

[0033] In a specific adjustment implementation method, the longitudinal adjustment structure is implemented as follows: a first positioning groove 10 is provided on the body positioning fixation plate 9 along its length direction, and a third positioning post 8 is provided on the connecting piece 5. By selectively locking the third positioning post 8 to different positions of the first positioning groove 10, the longitudinal (i.e., head-to-toe direction) position of the head positioning plate 1 relative to the body positioning fixation plate 9 can be manually adjusted.

[0034] The lateral adjustment structure is implemented as follows: Connector 5 has multiple third positioning holes 11 arranged laterally. Correspondingly, the positioning plate 9 has a third positioning post 8. By locking this positioning post into different third positioning holes 11, the lateral (i.e., left-right) position of the head positioning plate 1 can be manually adjusted. For ease of operation, the third positioning post 8 can use a spring pin, a hand-tightening screw, or an eccentric locking structure to achieve quick locking and releasing. This multi-position adjustment allows for adaptation to patients of different body types and head and neck sizes, improving the accuracy and repeatability of positioning.

[0035] For the angle adjustment structure, this embodiment adopts a structure in which a rotating shaft and a positioning pin cooperate. The connecting piece 5 is provided with a first positioning hole 6 and a second positioning hole 7, while the head positioning plate 1 is provided with a first positioning post 3 and a second positioning post 4. The first positioning post 3 is inserted into the first positioning hole 6 to form a rotating shaft, allowing the head positioning plate 1 to deflect around this axis. Multiple second positioning holes 7 are typically provided, arranged in an arc shape. When the head positioning plate 1 rotates to the desired angle (e.g., to achieve a lateral flexion posture for the patient's neck), the second positioning post 4 is inserted into the corresponding second positioning hole 7 and locked to fix the deflection angle, enabling manual angle adjustment. This allows for flexible adjustment of the patient's head and neck lateral flexion angle according to the tumor location during simulated positioning and treatment, thereby expanding the range of beam direction selection and optimizing the irradiation path.

[0036] Furthermore, to improve positioning accuracy and assist operators in responding to minor patient displacements during treatment, the fixation device in this embodiment also incorporates a posture monitoring and data display mechanism. (Reference) Figure 1 The device includes an attitude monitoring unit 15 and an adjustment data display unit 19. The attitude monitoring unit 15 is used to detect the spatial position of the head positioning plate 1 in real time, and its specific implementation is as follows: In a preferred example, the attitude monitoring unit 15 can be multiple optical markers disposed on the head positioning plate 1, in conjunction with an external optical tracking camera 17. The optical markers can be infrared reflective spheres with a diameter of 5mm to 10mm, with at least three spheres arranged non-collinearly on the back or side of the head positioning plate 1. The optical tracking camera 17 can employ a dual-camera stereo vision system with a sampling frequency of not less than 60Hz and a spatial positioning accuracy better than 0.5mm. The system calculates the six-degree-of-freedom pose of the head positioning plate 1 in real time by identifying the spatial coordinates of the reflective spheres.

[0037] In another alternative example, the attitude monitoring unit 15 can be an inertial measurement unit 18 integrated on the head positioning plate 1, which calculates its attitude changes in real time by acquiring acceleration and angular velocity signals. The inertial measurement unit 18 has the advantages of small size and no need for external tracking equipment, making it suitable for scenarios with high requirements for device portability. The adjustment data display unit 19, based on the deviation between the current spatial position and the preset target position fed back by the posture monitoring unit 15, issues an audible and visual alarm signal to prompt the operator to manually intervene for dynamic compensation. Specifically, the adjustment data display unit 19 includes an alarm (e.g., a buzzer or LED indicator) for displaying the alarm signal. When the detected longitudinal deviation exceeds a preset safety threshold (e.g., ±2mm), the alarm sounds, and the operator manually loosens the third positioning post 8, fine-tunes the longitudinal position of the connector 5 along the first positioning groove 10, and then relocks it, thereby correcting the head positioning plate 1 back to the target position. Since the lateral adjustment structure and angle adjustment structure are manually locked before treatment begins, they are generally not adjusted during treatment; if the lateral or angle deviation exceeds the safety range, treatment must be interrupted, and the operator must manually reposition the device.

[0038] It should be noted that this device does not contain any automatic drive motors; all adjustments (including dynamic compensation during treatment) are performed manually by the operator based on the deviation information provided by the adjustment data display unit 19. While ensuring positioning accuracy, this simplifies the equipment structure, reduces the risk of failure, and allows operators to flexibly determine the timing and amount of compensation based on clinical experience.

[0039] To ensure treatment safety, the adjustment data display unit 19 is also equipped with limit judgment logic. When the longitudinal deviation exceeds the preset absolute safety range (e.g., ±15mm), the system issues a continuous emergency alarm, prompting the operator to immediately interrupt the treatment and re-perform a complete position verification and manual positioning. At the same time, an emergency stop button 22 is provided in the treatment room, allowing the operator to interrupt the treatment at any time to ensure patient safety.

[0040] In addition, to facilitate patients' independent adjustment and maintenance of a comfortable and stable position, the positioning fixation plate 9 is equipped with an array of fixing holes (i.e., multiple handle sockets 12) on both sides for mounting auxiliary grips. Patients can grasp the auxiliary grips mounted on the handle sockets 12 to maintain body stability during positioning, thereby increasing the accuracy and repeatability of positioning. At the same time, to facilitate docking with external equipment, the positioning fixation plate 9 is also provided with a second positioning groove 13 and positioning holes 14 for docking and locking with a CT bed or treatment bed, and quick and reliable fixation can be achieved with standard accessories such as adapter strips.

[0041] Reference Figure 7 This embodiment provides a positioning method for the aforementioned patient fixation device. This method organically combines patient imaging information, device adjustment, and treatment implementation through streamlined operational steps. Specifically, the method includes the following steps: S1 (Pre-assessment and Pre-positioning): First, the location of the tumor is determined based on the patient's previous imaging data, and an assessment is conducted considering the patient's tolerance. This step requires determining the direction and angle of the patient's neck lateral flexion, and, based on the patient's body type and target area location, initially selecting the positioning holes to be used on the patient fixation device (such as the position of the first positioning slot 10, the third positioning hole 11, and the second positioning hole 7), while simultaneously planning the rotation angle and position of the treatment bed. Based on this information, the patient is pre-positioned to verify the feasibility of the treatment plan.

[0042] S2 (Simulation Positioning and Parameter Recording): In the simulation positioning room, precise positioning is performed according to the parameters determined in step S1. Specifically, two sets of adapter strips are used to connect the second positioning groove 13 and positioning hole 14 on the positioning fixation plate 9, locking the plate onto the CT bed. The longitudinal and lateral positions and deflection angles of the head positioning plate 1 are precisely adjusted using the adjustment structure of the connector 5 to reproduce the patient's position determined in the pre-assessment. After positioning, the head positioning membrane is inserted into the fixation hole 2, and the patient grips the auxiliary handle to achieve rigid fixation and ensure position repeatability. All positioning hole parameters used are recorded. Subsequently, a CT scan is used to acquire patient images with marked points. During this process, the association between the target position and the image coordinate system needs to be established: the target area position in the CT image coordinate system is registered with the spatial position of the head positioning plate 1 measured by the posture monitoring unit 15, establishing a coordinate mapping relationship from image space to treatment space, and storing the six-degree-of-freedom pose data in this state as the preset target position.

[0043] S3 (Reproduction Verification and Parameter Optimization): In the pre-positioning room, using the patient fixation device, positioning membrane, and grip handles, the patient's treatment posture is reproduced based on the positioning parameters recorded in S2. The current position is registered with the images from the simulated positioning using an image-guided system (such as CBCT) to verify and correct positioning errors. Subsequently, based on the relative position of the patient's treatment site and the exit beam of the treatment head, the optimal rotation angle and position of the treatment bed are determined, and the corresponding motion parameters are recorded. If it is found that the target area cannot be optimally positioned near the exit beam due to the patient's posture, the process can be repeated in step S2, adjusting the settings of the patient fixation device and the patient's posture, performing a new simulated positioning, and updating the CT images.

[0044] S4 (Formal Treatment): After the patient enters the treatment room, the treatment bed is first moved to the optimal rotation angle and position determined in step S3. Then, using the same patient fixation device, the patient's treatment posture is reproduced strictly according to the positioning parameters (positioning hole positions, etc.) recorded in step S2, and the patient is secured using a positioning membrane and auxiliary handles. At this point, all preparations are complete, and the treatment equipment can be started to perform precise boron neutron capture therapy on the patient.

[0045] S5 (Dynamic Monitoring and Compensation): During treatment, the posture monitoring unit 15 continuously operates, monitoring the spatial position of the head positioning plate 1 in real time. When the longitudinal deviation of the detected value from the preset target position exceeds the set safety threshold, the alarm of the adjustment data display unit 19 emits an audible and visual alarm to alert the operator. The operator then manually adjusts the longitudinal adjustment structure: loosening the third positioning post 8, finely adjusting the longitudinal position of the connector 5 along the first positioning groove 10 to return the head positioning plate 1 to the target position, and then re-locking the third positioning post 8 to complete dynamic compensation. If the lateral or angular deviation exceeds the threshold, the operator also manually loosens the corresponding positioning post, readjusts, and then locks it again. Through the above-mentioned manual intervention compensation method, the target area positioning accuracy throughout the treatment process is ensured.

[0046] Through the above-described device and method, the present invention can effectively overcome the geometric interference problem of traditional fixation devices, achieve a better positioning angle and higher target area positioning accuracy while ensuring patient comfort. At the same time, the posture monitoring and data display unit assists the operator in performing manual dynamic compensation, thereby improving the overall effect of boron neutron capture therapy.

[0047] The above description is merely a preferred embodiment of the present invention and does not limit the patent scope of the present invention. Any equivalent structural or procedural transformations made based on the content of the present invention's specification and drawings, or direct or indirect applications in other related technical fields, are similarly included within the patent protection scope of the present invention.

Claims

1. A patient fixation device for boron neutron capture therapy, comprising a body positioning plate (9), a head positioning plate (1), and a connector (5) connecting the body positioning plate (9) and the head positioning plate (1); Its features are, The two sides of the body positioning plate (9) taper inward at the corresponding position on the shoulder to form a shoulder avoidance structure; The head positioning plate (1) is equipped with a switchable supine position dedicated component and a prone position dedicated component; The connector (5) is detachably connected to the body positioning plate (9) and the head positioning plate (1) respectively, and has a longitudinal adjustment structure for adjusting the relative position of the head positioning plate (1) in the longitudinal direction, a lateral adjustment structure for adjusting the relative position of the head positioning plate (1) in the lateral direction, and an angle adjustment structure for adjusting the deflection angle of the head positioning plate (1) relative to the body positioning plate (9). The patient fixation device also includes a posture monitoring unit (15) and an adjustment data display unit (19). The posture monitoring unit (15) is used to detect the spatial position of the head positioning plate (1) in real time. The adjustment data display unit (19) is used to dynamically compensate the position of the head positioning plate (1) by manually driving the longitudinal adjustment structure based on the deviation between the spatial position fed back by the posture monitoring unit (15) and the preset target position. Both the lateral adjustment structure and the angle adjustment structure are manually adjustable through the cooperation of the positioning pin and the positioning hole.

2. The patient fixation device for boron neutron capture therapy according to claim 1, characterized in that, The attitude monitoring unit (15) includes multiple optical markers set on the head positioning plate (1) and an optical tracking camera (17) that cooperates with the optical markers.

3. The patient fixation device for boron neutron capture therapy according to claim 1, characterized in that, The attitude monitoring unit (15) includes an inertial measurement unit (18) disposed on the head positioning plate (1), the inertial measurement unit (18) being used to collect the acceleration signal and angular velocity signal of the head positioning plate (1).

4. The patient fixation device for boron neutron capture therapy according to claim 1, characterized in that, The adjustment data display unit (19) includes an alarm for displaying alarm signals.

5. The patient fixation device for boron neutron capture therapy according to claim 1, characterized in that, The head positioning plate (1) is switched to the supine position special component or the prone position special component via a quick-release interface.

6. The patient fixation device for boron neutron capture therapy according to claim 1, characterized in that, The longitudinal adjustment structure includes a first positioning groove (10) provided on the body positioning plate (9) along its width direction, and a third positioning post (8) provided on the connector (5). The third positioning post (8) is selectively locked in different positions of the first positioning groove (10) to realize the longitudinal manual adjustment of the head positioning plate (1). The lateral adjustment structure includes a plurality of third positioning holes (11) arranged laterally on the connector (5), and the third positioning post (8) is set on the body positioning plate (9). The third positioning post (8) is selectively locked into different third positioning holes (11) to realize the lateral manual adjustment of the head positioning plate (1).

7. The patient fixation device for boron neutron capture therapy according to claim 1, characterized in that, The angle adjustment structure includes a first positioning hole (6) and a second positioning hole (7) disposed on the connector (5), and a first positioning post (3) and a second positioning post (4) disposed on the head positioning plate (1). The first positioning post (3) and the first positioning hole (6) form a rotation axis, and the second positioning post (4) is selectively locked with one of the second positioning holes (7) to lock the deflection angle of the head positioning plate (1) and realize manual angle adjustment.

8. The patient fixation device for boron neutron capture therapy according to claim 1, characterized in that, The body positioning plate (9) is also provided with an array of fixing holes on both sides for installing auxiliary grips.

9. The patient fixation device for boron neutron capture therapy according to claim 1, characterized in that, The body positioning plate (9) is also provided with a second positioning groove (13) and a positioning hole (14) for docking and locking with a CT bed or treatment bed.

10. A method for positioning a patient fixation device for boron neutron capture therapy, characterized in that, Includes the following steps: S1: Based on the patient's imaging data, determine the direction and angle of the patient's neck lateral flexion, and determine the initial positioning hole selection parameters of the patient fixation device as described in any one of claims 1 to 9 and the rotation angle and position of the treatment bed, and pre-position the patient; S2: In the simulation positioning room, according to the parameters determined in S1, the longitudinal and lateral positions and deflection angles of the head positioning plate (1) relative to the body positioning plate (9) are adjusted by the connector (5), and the patient is fixed on the patient fixation device. The positioning parameters are recorded, and the current spatial position of the head positioning plate (1) is set as the preset target position. S3: In the pre-positioning room, the patient's position is reproduced according to the positioning parameters recorded in S2. The positioning is verified and corrected through the image guidance system. The optimal rotation angle and position of the treatment bed are determined according to the relative position of the patient's treatment site and the outlet of the treatment head. S4: After the patient enters the treatment room, the treatment bed is adjusted according to the determined optimal rotation angle and position, and the patient's position is reproduced through the patient fixation device according to the positioning parameters recorded in S2. S5: During the treatment, the spatial position of the head positioning plate (1) is detected in real time by the posture monitoring unit (15). When the deviation between the detected value and the preset target position exceeds the threshold, the position of the head positioning plate (1) is dynamically compensated by manually adjusting the longitudinal adjustment structure.

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