Preparation process of a composite bioactive peptide lip gloss body and emulsifying device thereof

Abstract

The present application relates to a kind of composite bioactive peptide lip gloss paste preparation process and its emulsifying device, belong to lip gloss paste preparation technical field, preparation process includes color paste pre-preparation, matrix melting, homogenization emulsification, vacuum cooling defoaming, polypeptide loss package, curing and filling step in sequence, by stage process design, with polypeptide low-temperature low shear mixing isolation, whole process vacuum closed operation, avoid the destruction of polypeptide by mechanical shear and high temperature, simultaneously realize paste depth defoaming oxygen removal, emulsifying device includes frame, support base, sampling device, feed conduit and drive component, frame can be lifted lifting seat and stirring main shaft, stirring paddle is equipped with full-coverage heat-conducting plate, main shaft and paddle are equipped with medium channel to realize accurate temperature control, feed conduit is equipped with dispersion disc and discharge cover to realize material dispersion feeding, the present application solves the problems, such as polypeptide inactivation, powder agglomeration, temperature control uneven, sampling pollution in traditional preparation, improves polypeptide retention rate.

Description

Technical Field

[0001] This invention belongs to the field of lip gloss preparation technology, and relates to a lip gloss preparation process and emulsification device for a composite bioactive peptide. Background Technology

[0002] As a mainstream lip makeup product, the texture, color payoff, and functionality of lip gloss are the core indicators for measuring product quality. With the increasing demand for functional skincare and makeup products in the beauty consumer market, functional lip glosses with added complex bioactive peptides have become a research hotspot. Complex bioactive peptides have the effects of moisturizing and repairing lip skin, which can effectively improve problems such as dry lips and fine lines, greatly enhancing the use value of lip gloss. However, complex bioactive peptides themselves have the characteristics of strong heat sensitivity, poor mechanical shear tolerance, and easy oxidation and inactivation. Stable addition of them to the lip gloss formula while taking into account the molding quality of the lip gloss itself has become a technical challenge in the field of lip gloss preparation.

[0003] Lip glosses are typically high-viscosity oil-water emulsion systems. Traditional lip gloss manufacturing processes usually involve feeding oils, pigments, aqueous raw materials, and functional ingredients together into an emulsification device, using a single high-shear homogenization method for mixing and emulsification. However, the emulsification equipment used in these traditional processes suffers from numerous compatibility issues and cannot meet the requirements for preparing complex bioactive peptide lip glosses. Specific problems include the following: Firstly, the temperature control of traditional emulsification devices relies solely on the water / oil jacket on the outside of the tank. Lip gloss has extremely high viscosity and low heat conduction efficiency, which easily leads to a large temperature difference between the tank wall and the center of the gloss inside the tank. Local high-temperature areas inside the tank can cause the injected peptides to be instantly deactivated, while low-temperature areas can affect the uniformity of emulsification. Secondly, traditional devices often use a top-feed method for feeding powder / functional ingredients. When the powder falls onto the surface of a high-viscosity paste, it is prone to forming "fish-eye" clumps due to surface tension. Conventional stirring structures cannot break them up, resulting in a grainy texture in the finished lip gloss and uneven distribution of active ingredients. Thirdly, the degassing method of traditional devices relies solely on vacuum vents to remove air from above the liquid surface, allowing the bubbles to rise and burst due to their own buoyancy. However, the tiny bubbles deep within the high-viscosity paste are unable to overcome fluid resistance and rise, resulting in permanent bubble retention. This not only affects the smoothness of lip gloss application, but the oxygen inside the bubbles also slowly oxidizes and degrades peptides, reducing the product's shelf life. Fourth, traditional sampling methods often involve direct discharge from the bottom ball valve or sampling by opening the lid after stopping the machine. High-viscosity pastes can easily cause blockage of the ball valve, and both methods will disrupt the vacuum environment inside the tank, introducing external oxygen and bacteria, which will cause large-scale oxidation and inactivation of the uncoated peptides inside the tank, resulting in a decline in the quality of the entire batch of products.

[0004] Therefore, we propose a process for preparing lip gloss with composite bioactive peptides and its emulsification device to solve the problems mentioned above. Summary of the Invention

[0005] In view of the following defects in the existing technology: traditional lip gloss preparation involves emulsifying all raw materials at one time with high shear, which leads to the rapid deactivation of heat-sensitive composite bioactive peptides due to high temperature / strong shear / local temperature difference / oxidation; temperature control by the tank wall jacket generates a high viscosity paste with a central temperature difference; direct top pouring easily forms powder agglomeration; conventional sampling disrupts the vacuum and introduces oxygen / bacteria; degassing by buoyancy alone cannot remove deep bubbles, this paper provides a lip gloss paste preparation process and emulsification device with composite bioactive peptides.

[0006] To achieve the above objectives, the present invention provides the following technical solution: a process for preparing a lip gloss containing composite bioactive peptides, comprising the following steps performed sequentially: S1. Pre-preparation of color paste: The oil and color powder are mixed in the formula ratio and then subjected to multiple high-intensity grinding processes to completely coat the surface of the color powder with oil, thus obtaining a pre-prepared color paste. S2, Matrix melting: The structural lipid, synthetic oil and the pre-made color paste are mixed and heated to completely melt to form an oil phase, and deionized water and humectant are heated and dissolved to form an aqueous phase; S3. Homogenization and emulsification: The oil phase and water phase are mixed under vacuum and constant temperature conditions, and the emulsification is carried out by high shear homogenization and frame-type wall scraping and stirring to form a lip gloss base with a network structure. S4. Vacuum cooling and degassing: Stop high shear homogenization, maintain high vacuum in the system and keep low-speed wall scraping and stirring, and cool the paste steadily to below the inactivation critical point of the complex bioactive peptides to achieve deep degassing of the paste and deoxygenation of the system. S5. Non-destructive encapsulation of peptides: At a temperature below the inactivation critical point, the composite bioactive peptide solution and heat-sensitive components are injected into the ointment through a closed feeding system. Only a very low rotation speed is used to perform flexible physical mixing of the ointment to avoid mechanical shearing that could damage the molecular structure of the composite bioactive peptides. S6. Curing and Filling: Release the system vacuum, transport the evenly mixed paste to a sealed curing tank for static curing, and then fill the paste in a light-proof and aseptic manner to avoid oxidation and inactivation of the complex bioactive peptides.

[0007] An emulsification device for preparing lip gloss with a complex bioactive peptide, applied to the above-mentioned lip gloss preparation process with a complex bioactive peptide, includes: a frame, a lifting seat vertically slidably connected to the top of the frame, a stirring main shaft vertically penetrating and rotatably connected to the bottom of the lifting seat, a sealing end cap rotatably sleeved on the outer wall of the bottom end of the stirring main shaft, a connecting ring fixedly sleeved on the bottom end of the stirring main shaft, a plurality of stirring blades circumferentially fixed to the outer wall of the connecting ring, a support ring being fixedly connected to the top of the plurality of stirring blades, and the support ring being sleeved on the outside of the stirring main shaft; A support base is fixed to one side of the frame. An emulsifying tank is rotatably connected between the support base and the frame. The emulsifying tank is coaxially arranged with the stirring main shaft. The sealing end cap is adapted to the top opening of the emulsifying tank to achieve vacuum sealing. A sampling device is detachably connected to the outer wall of an emulsifying tank. The sampling device includes a sampling cylinder that is connected to the emulsifying tank. A spiral conveying rod II is axially inserted and rotatably connected inside the sampling cylinder. When the spiral conveying rod II rotates, it sucks up and pushes the paste inside the emulsifying tank into the sampling cylinder. A feeding conduit is vertically penetrating and rotatably connected to a lifting seat and a sealing end cap. A storage tank is fixedly connected to the top of the feeding conduit, and the storage tank is connected to the inside of the feeding conduit. A dispersing disc is fixedly connected to the bottom of the feeding conduit. A discharge hood is fixedly fitted on the outer wall of the bottom of the feeding conduit, and the discharge hood is located on top of the dispersing disc. Discharge ports are opened on the side walls of both the feeding conduit and the discharge hood. Multiple guide teeth are integrally formed on the side of the dispersing disc away from the feeding conduit. Drive motor I and drive motor II are both fixedly connected inside the lifting base. The output shaft of drive motor I is driven to rotate the stirring main shaft. The output shaft of drive motor II is driven to rotate the feeding conduit. After the material in the storage tank is discharged through the feeding conduit and the discharge port of the discharge hood, it is further dispersed and injected into the emulsification tank through the dispersion disc and guide teeth.

[0008] As a further improvement to the above technical solution: A hydraulic cylinder is vertically penetrating and fixed to the top of the frame, and a guide column is vertically penetrating and slidably connected to the top of the frame. The top of the guide column and the piston rod of the hydraulic cylinder are both fixed to the bottom wall of the lifting seat. The extension and retraction of the piston rod of the hydraulic cylinder drives the lifting seat to slide along the axial direction of the guide column, thereby causing the sealing end cover to fit or separate from the top opening of the emulsification tank.

[0009] The supporting base and the frame are both horizontally connected to rotating main shafts on opposite sides. The two ends of the emulsifying tank are fixedly connected to the opposite ends of the two rotating main shafts. The rotating main shaft located in the supporting base is a hollow structure and is connected to the interior of the emulsifying tank. A worm wheel is fixedly sleeved on the outer wall of the rotating main shaft. A worm is horizontally connected to the supporting base and rotated. The worm meshes with the worm wheel. Rotating the worm drives the rotating main shaft to rotate through the worm wheel, thereby driving the emulsifying tank to rotate around the axis of the rotating main shaft.

[0010] The sampling cylinder is inserted into the rotating main shaft of the support base at one end away from the emulsification tank. A valve plate is vertically slidably connected to the outer wall of the emulsification tank. A plug-in port is opened at the top of the rotating main shaft. The bottom end of the valve plate is adapted to the plug-in port to realize the opening and closing of the sampling channel. A lead screw is vertically rotatably connected to the outer wall of the emulsification tank. The valve plate is threaded onto the bottom end of the lead screw. Rotating the lead screw drives the valve plate to slide along the lead screw axis to realize the plug-in or separation of the valve plate and the plug-in port.

[0011] The outer wall of the sampling cylinder is fixedly fitted with a positioning collar. A plurality of limiting pins are circumferentially fixed to one side of the positioning collar near the rotating main shaft. The limiting pins are inserted into the end of the rotating main shaft to achieve circumferential and axial positioning of the sampling cylinder and the rotating main shaft.

[0012] A spiral conveying rod I is fixedly fitted at the bottom end of the stirring spindle. A guide sleeve is fitted on the outer wall of the stirring spindle, and the guide sleeve is located outside the spiral conveying rod I. Multiple connecting pillars are circumferentially fixed to the top of the guide sleeve. A dispersion guide hood is rotatably fitted on the outer wall of the stirring spindle. The bottom wall of the dispersion guide hood is fixedly connected to the top of the multiple connecting pillars. Multiple discharge ports are formed between the inner wall of the dispersion guide hood and the outer wall of the guide sleeve. A suspension pillar is fixedly connected between the bottom wall of the sealing end cap and the top wall of the dispersion guide hood. The rotation of the stirring spindle drives the spiral conveying rod I to convey the paste from the bottom of the emulsion tank upwards. After being discharged through the discharge ports, it is guided by the dispersion guide hood to diffuse evenly in all directions.

[0013] Each of the stirring blades has a heat-conducting plate I fixedly connected to its inner sidewall, and a heat-conducting plate II fixedly connected to its bottom wall. Both the stirring blades and the stirring shaft have water inlet and drainage channels. The water inlet and drainage channels of the stirring blades are connected to the water inlet and drainage channels of the stirring shaft, respectively. The water inlet ends of heat-conducting plates I and II are connected to the water inlet channels of the stirring blades through pipes, and the drainage ends of heat-conducting plates I and II are connected to the drainage channels of the stirring blades through pipes.

[0014] Rotary joint I and rotary joint II are rotatably connected to the top of the stirring spindle. Rotary joint I is connected to the drainage channel of the stirring spindle, and rotary joint II is connected to the water inlet channel of the stirring spindle. Cold and hot media enter the water inlet channel of the stirring spindle and the stirring blade through rotary joint II, flow through heat-conducting plate I and heat-conducting plate II to exchange heat with the paste, and are discharged through the drainage channel and rotary joint I.

[0015] The positions of the multiple heat-conducting plates II are adjusted outward in sequence along the radial direction of the stirring main shaft and completely cover the bottom wall of the emulsification tank. The height of the multiple heat-conducting plates I is adjusted upward in sequence along the axial direction of the stirring main shaft and completely cover the inner wall of the emulsification tank, so as to realize all-round, dead-angle-free heat exchange of the paste in the emulsification tank and eliminate the local temperature difference of the high-viscosity paste.

[0016] The internal precise temperature control structure of this invention provides a uniform and stable low-temperature environment for peptide feeding, avoiding instantaneous peptide inactivation caused by local high temperatures, and laying the temperature foundation for subsequent non-destructive peptide encapsulation. The circulating deep degassing structure completely removes micro-bubbles deep within the paste, and together with the fully vacuum-sealed system, achieves full-process deoxygenation of the paste, avoiding the slow oxidative degradation of peptides by oxygen. The sealed dispersion feeding structure ensures uniform dispersion of the peptide solution, avoiding problems such as pigment agglomeration and uneven distribution of active ingredients. At the same time, the fully sealed system does not introduce external oxygen, ensuring an anaerobic environment. The vacuum-preserving sampling structure prevents the vacuum environment from being disrupted during sampling, preventing the introduction of external oxygen and bacteria, and ensuring an anaerobic and sterile environment throughout the process. Together, these technologies solve the defects of existing technologies, such as easy peptide inactivation, powder agglomeration, uneven temperature control, and sampling contamination.

[0017] The beneficial effects of this invention are as follows: 1. The present invention discloses an emulsification device for preparing lip gloss paste with composite bioactive peptides. The stirring blade is equipped with heat-conducting plate I and heat-conducting plate II. Multiple heat-conducting plates I and II cover the inner wall and bottom wall of the emulsification tank respectively. The stirring shaft and stirring blade have interconnected water inlet and drainage channels and are equipped with rotary joints, so that cold and hot media can be directly transported to the inside of the paste to achieve heat exchange. Compared with the traditional tank wall jacket temperature control, the heat exchange specific surface area is greatly increased, and the temperature of the paste is accurately controlled in all directions without dead angles. The problem of local temperature difference in high viscosity paste is completely eliminated, ensuring that the temperature inside the tank is uniform and stable when the peptide is injected, and avoiding peptide inactivation caused by local high temperature. 2. The lip gloss preparation emulsification device disclosed in this invention, consisting of a feeding conduit, a storage tank, and a dispersion disc, allows raw materials such as powder and polypeptide solution in the storage tank to be transported through the feeding conduit and discharged from the outlet under centrifugal force. After secondary dispersion by the guide teeth of the dispersion disc, the materials are injected into the lip gloss. Simultaneously, the spiral conveying rod I at the bottom of the stirring shaft and the dispersion guide structure ensure that the lip gloss at the bottom of the tank is continuously transported upward and evenly diffused. This effectively prevents the formation of lumps when the powder comes into contact with the high-viscosity lip gloss, ensuring that the raw materials are evenly distributed in the lip gloss. This solves the "fish-eye" problem of traditional top feeding, resulting in a lip gloss without a grainy texture and smooth application. 3. The lip gloss emulsification device for preparing composite bioactive peptides disclosed in this invention controls the opening and closing of the sampling channel through a screw and valve plate. During sampling, only the plug-in port needs to be opened, and the paste is sucked into the sampling cylinder by the spiral conveyor rod II. After sampling, the channel can be quickly sealed. The entire process does not require breaking the vacuum sterile environment of the emulsification tank, which solves the problem of easy introduction of oxygen and bacteria in traditional sampling methods. At the same time, the suction structure of the spiral conveyor rod II is suitable for high viscosity paste sampling, avoiding the clogging problem of traditional ball valve sampling, and realizing sterile and convenient paste sampling. 4. The emulsification device for preparing lip gloss with composite bioactive peptides disclosed in this invention has a spiral conveying rod I at the bottom of the stirring shaft. Together with the discharge port formed by the dispersion guide and the guide sleeve, the paste at the bottom of the emulsification tank can be continuously conveyed upward and diffused in all directions. Under vacuum conditions, the paste forms a continuous flow circulation. Combined with the high vacuum environment of the tank, the deep micro bubbles in the paste can be smoothly floated to the surface and extracted, realizing deep defoaming of the paste. This avoids the problem of poor texture of lip gloss caused by bubble retention. At the same time, it eliminates the slow oxidation of peptides by oxygen in the bubbles, further improving product quality and shelf life.

[0018] Other advantages, objectives, and features of the invention will be set forth in part in the description which follows, and in part will be apparent to those skilled in the art from the following examination, or may be learned from practice of the invention. The objectives and other advantages of the invention can be realized and obtained through the following description. Attached Figure Description

[0019] To make the objectives, technical solutions, and advantages of the present invention clearer, the preferred embodiments of the present invention will be described in detail below with reference to the accompanying drawings, wherein: Figure 1 This is a three-dimensional structural schematic diagram of an emulsification device for preparing a lip gloss paste containing a composite bioactive peptide, according to the present invention. Figure 2 This is a schematic cross-sectional view of the support base of the emulsification device for preparing a lip gloss paste containing a composite bioactive peptide according to the present invention. Figure 3 This is a cross-sectional schematic diagram of the sampling device of the emulsification apparatus for preparing a lip gloss paste containing a composite bioactive peptide according to the present invention. Figure 4 This is a schematic diagram of the internal structure of the lifting seat of the emulsification device for preparing a lip gloss paste containing a composite bioactive peptide according to the present invention. Figure 5 This is a schematic diagram of the stirring blade structure of the emulsification device for preparing a lip gloss paste containing a composite bioactive peptide according to the present invention. Figure 6This is a schematic diagram of the dispersion disk structure of the emulsification device for preparing a lip gloss paste containing a composite bioactive peptide according to the present invention. Figure 7 This is a schematic diagram of the guide sleeve and dispersion guide cover structure of the emulsification device for preparing a lip gloss paste containing a composite bioactive peptide according to the present invention.

[0020] Reference numerals: 1. Frame; 2. Hydraulic cylinder; 3. Guide column; 4. Lifting seat; 41. Drive motor I; 42. Drive motor II; 5. Stirring shaft; 51. Rotary joint I; 52. Rotary joint II; 53. Dispersion guide shroud; 54. Spiral conveyor rod I; 55. Guide sleeve; 56. Suspension support column; 57. Connecting support column; 58. Discharge port; 6. Sealing end cap; 7. Stirring blade; 71. Heat-conducting plate I; 72. Heat-conducting plate II; 73. Connecting ring; 74. Support ring; 8. Feed conduit; 81. Dispersion disc; 811. Guide tooth; 82. Discharge hood; 9. Support base; 10. Emulsifying tank; 11. Sampling device; 111. Sampling cylinder; 112. Screw conveyor II; 113. Positioning collar; 114. Limiting pin; 115. Insertion port; 12. Storage tank; 13. Rotating main shaft; 14. Worm gear; 15. Worm; 16. Valve plate; 17. Lead screw. Detailed Implementation

[0021] The following specific examples illustrate the implementation of the present invention. Those skilled in the art can easily understand other advantages and effects of the present invention from the content disclosed in this specification. The present invention can also be implemented or applied through other different specific embodiments, and various details in this specification can be modified or changed based on different viewpoints and applications without departing from the spirit of the present invention. It should be noted that the illustrations provided in the following embodiments are only schematic representations of the basic concept of the present invention. Unless otherwise specified, the following embodiments and features can be combined with each other.

[0022] The accompanying drawings are for illustrative purposes only and are schematic diagrams, not actual pictures, and should not be construed as limiting the invention. To better illustrate the embodiments of the invention, some parts in the drawings may be omitted, enlarged, or reduced, and do not represent the actual product dimensions. It is understandable to those skilled in the art that some well-known structures and their descriptions may be omitted in the drawings.

[0023] In the accompanying drawings of the embodiments of the present invention, the same or similar reference numerals correspond to the same or similar components. In the description of the present invention, it should be understood that if terms such as "upper," "lower," "left," "right," "front," and "rear" indicate the orientation or positional relationship based on the orientation or positional relationship shown in the drawings, they are only for the convenience of describing the present invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, the terms used to describe positional relationships in the drawings are only for illustrative purposes and should not be construed as limiting the present invention. For those skilled in the art, the specific meaning of the above terms can be understood according to the specific circumstances.

[0024] Example 1 A process for preparing a lip gloss containing a complex bioactive peptide involves sequential steps including pigment pretreatment, matrix melting, homogenization emulsification, vacuum cooling and degassing, non-destructive peptide encapsulation, curing, and filling. The entire process is controlled around the critical point of inactivation of the complex bioactive peptide, ensuring the lip gloss base's molding effect and stability while achieving non-destructive retention of the complex bioactive peptide. The specific operation methods for each step are as follows: S1 Pigment Preparation: Weigh the oil and pigment raw materials according to the preset formula ratio for lip gloss, and put them together into a horizontal mixing device for preliminary mixing. During the mixing process, continuously stir until there are no obvious dry powder agglomerates to avoid local accumulation of pigment. Then, transfer the pre-mixed material to a grinding device for multiple high-intensity grinding operations. During grinding, the material is squeezed and ground by rollers or grinding balls in the equipment, and the pigment particles are gradually refined. The state of the material is continuously observed during the grinding process until the surface of the pigment is completely coated with oil to form a uniform and particle-free paste, thus obtaining a pre-made pigment that meets the fineness requirements. After grinding, the pre-made pigment is immediately transferred to a sealed storage tank for later use. The storage tank is sealed with a lid to prevent the pigment from direct contact with air throughout the process, thus preventing oxidation, discoloration, moisture absorption, and clumping.

[0025] S2 Matrix Melting: Weigh out the structural lipids and synthetic oils according to the formula ratio, and add them together with the pre-made color paste obtained in S1 into an oil phase melting tank equipped with a heating jacket and a stirring paddle. Close and seal the feed port of the oil phase melting tank, and turn on the heating and stirring systems of the oil phase melting tank. The stirring paddle rotates slowly to mix the materials in the tank, ensuring that the materials are heated evenly until they are completely melted to form a homogeneous, non-layered oil phase. At the same time, weigh out deionized water and humectant according to the formula ratio, and add them to another aqueous phase dissolving tank equipped with the same heating and stirring structure. Turn on the heating and stirring systems simultaneously, avoiding the generation of excessive bubbles during stirring, and ensuring that the humectant is completely dissolved in the deionized water to form a homogeneous aqueous phase. After the oil phase and aqueous phase preparations are completed, keep them under heating to maintain a constant temperature in the tanks and prevent solidification, layering, or precipitation of the humectant due to temperature drop.

[0026] S3 Homogenization and Emulsification: The oil phase and water phase obtained in S2 are transported together to the emulsification tank 10 through a sealed stainless steel pipeline. During the transport process, the flow rate of the pipeline is controlled to avoid material splashing or the formation of bubbles. After the transport is completed, the hydraulic cylinder 2 is activated to move the lifting seat 4 downward, so that the sealing end cap 6 fits against the top opening of the emulsification tank 10, and the tank is sealed by the sealing ring on the edge of the sealing end cap 6. Then, the emulsification tank 10 is evacuated by an external vacuum unit, and the temperature control system connected to the stirring shaft 5 is turned on to maintain a constant temperature environment inside the tank. Next, the drive motor I41 is started, which drives the stirring shaft 5 and the bottom stirring blades 7 and the spiral conveyor rod I54 to rotate synchronously. While the stirring blades 7 scrape the wall and stir, the spiral conveyor rod I54 conveys the material at the bottom of the tank upward, realizing the simultaneous operation of high shear homogenization and frame-type wall scraping and stirring. Under the dual stirring action, the oil phase and water phase are fully integrated and undergo an emulsification reaction until the oil phase and water combine to form a lip gloss base with a stable three-dimensional network structure. Throughout the process, the emulsification tank 10 is kept under vacuum and constant temperature to prevent the substrate from coming into contact with air or to prevent temperature fluctuations from affecting the formation and stability of the mesh structure.

[0027] S4 Vacuum Cooling and Defoaming: After completing the homogenization and emulsification process in S3, adjust the operating mode of drive motor I41 to stop the high-shear homogenization process. Then, restart drive motor I41 and adjust it to low-speed mode to maintain the low-speed wall-scraping stirring state of the stirring blades 7, ensuring the paste remains in a slow-flowing state. Simultaneously, maintain the vacuum level inside the emulsification tank 10 in the high-vacuum range through the vacuum unit. Turn on the external temperature control unit to introduce cooling medium into the water inlet channel inside the stirring shaft 5. The cooling medium is transported through pipelines to the water inlet channel inside each stirring blade 7, and then distributed to heat-conducting plate I71 and heat-conducting plate II72. After sufficient heat exchange with the lip gloss base, it flows back to the drainage channel of the stirring shaft 5 through the drainage channel inside the stirring blades 7, and finally exits from the rotary joint I51. During the cooling process, the low-speed rotating stirring blades 7 drive the paste to flow slowly, ensuring uniform heating of all parts of the paste and achieving stable cooling until the paste temperature drops below the inactivation critical point of the complex bioactive peptides. The continuous high vacuum state during this process can gradually extract the tiny air bubbles remaining in the paste, while simultaneously achieving deoxygenation within the system, thus preventing the subsequent addition of peptides from being oxidized and deactivated upon contact with oxygen.

[0028] S5 Peptide Non-destructive Encapsulation: Under the premise that the temperature of the paste inside the emulsification tank 10 is stably maintained below the critical point of inactivation of the composite bioactive peptides, the pre-prepared composite bioactive peptide solution and various heat-sensitive components are added to the storage tank 12 through the feeding port, and the storage tank 12 is then sealed. Subsequently, the drive motor II 42 is turned on to slowly rotate the feed conduit 8. Under the combined action of gravity and the rotation of the feed conduit 8, the material in the storage tank 12 is slowly discharged through the outlet of the feed conduit 8 and smoothly injected into the lip gloss base inside the emulsification tank 10 through this closed feeding system. During the injection process, the material outflow rate is controlled to avoid excessively high local material concentrations. During the injection process, the stirring blade 7 is always kept in a low-speed wall-scraping stirring state. This low-speed stirring achieves flexible physical mixing of the composite bioactive peptide solution, heat-sensitive ingredients and lip gloss base, so that all kinds of ingredients are evenly dispersed in the lip gloss base. During this process, the emulsification tank 10 is kept in a sealed state to prevent external air from entering the tank. At the same time, high-shear homogenization operation is strictly prohibited to avoid mechanical shear force from damaging the molecular structure of the composite bioactive peptide.

[0029] S6 Curing and Filling: After the S5 flexible physical mixing is completed, the vacuum release valve on the emulsification tank 10 is slowly opened to allow the internal pressure of the tank to slowly return to normal pressure, releasing the vacuum state inside the tank. Then, the hydraulic cylinder 2 is activated to move the lifting seat 4 upwards, opening the sealed end cap 6. The evenly mixed paste is transferred through a sealed stainless steel conveying pipeline to a temperature-controlled, sealed curing tank, avoiding excessive contact between the paste and air during the transfer process. The paste remains stationary in the curing tank, which maintains a constant temperature and light-proof environment, further relaxing and stabilizing the paste's network structure, improving the smoothness and texture of the lip gloss. After curing, the paste is conveyed through a sterile conveying pipeline to a light-proof, aseptic filling device. The filling equipment operates in a sterile environment throughout the process, completing the lip gloss filling operation under completely light-proof and sterile conditions. The filled product is promptly sealed, completing the entire preparation process of the composite bioactive peptide lip gloss.

[0030] The preparation process in this embodiment involves orderly, staged operations for each step, strictly isolating the high-intensity treatment of the lip gloss base from the low-intensity mixing of the peptides. This effectively resolves the contradiction between the high-shear homogenization process requirements and the fragile and easily damaged nature of the peptides, achieving efficient retention of the complex bioactive peptides. At the same time, the vacuum and sealed operation throughout the process significantly reduces the risk of oxidation of the lip gloss. The resulting lip gloss is free of particles and air bubbles, has a smooth application texture, and the bioactive ingredients are evenly distributed in the lip gloss, ensuring the effectiveness and functionality of the lip gloss.

[0031] Example 2 Reference Figures 1-7 An emulsification device for preparing lip gloss paste with composite bioactive peptides can be directly applied to the preparation process of lip gloss paste with composite bioactive peptides in Example 1, so as to realize the mechanization and continuous operation of each step of lip gloss paste preparation.

[0032] The device includes a frame 1, which serves as the basic support structure for the entire device. It is constructed from high-strength steel and has a robust frame structure, effectively withstanding the weight of the components and vibrations during operation. A base plate with mounting holes is welded to the bottom of the frame 1, allowing it to be fixed to the ground with expansion bolts to prevent displacement during operation. A hydraulic cylinder 2 is fixedly mounted through the top surface of the frame 1. The cylinder body of the hydraulic cylinder 2 is connected to the top surface of the frame 1 via a flange structure, with a sealing gasket at the flange connection to improve sealing and stability. A guide column 3, made of high-strength round steel, slides through the top surface of the frame 1 and is connected to the top surface of the frame 1 via a linear bearing. The linear bearing facilitates smoother axial sliding of the guide column 3 and reduces frictional resistance during sliding. The top of the guide column 3 and the piston rod end of the output end of the hydraulic cylinder 2 are welded and fixed to the bottom end face of the lifting seat 4. When the hydraulic cylinder 2 is working, the piston rod makes axial extension and retraction movements, which can drive the lifting seat 4 to make smooth lifting and lowering movements along the axial direction of the guide column 3, realize the position adjustment of the lifting seat 4, and meet the requirements of opening and closing of the emulsification tank 10 and the extension and retraction of stirring components such as the stirring main shaft 5 and stirring blades 7.

[0033] The lifting base 4 is a hollow, box-shaped welded structure with ample internal installation space for various drive components. A stirring shaft 5 is vertically mounted on the top surface of the lifting base 4. The stirring shaft 5 is a solid, high-strength round shaft, connected to the lifting base 4 via a deep groove ball bearing. An oil seal is installed between the bearing and the stirring shaft 5 to prevent dust and impurities from entering the bearing, ensuring the smooth rotation of the stirring shaft 5. Drive motor I 41 and drive motor II 42 are bolted to the inside of the lifting base 4. The output shaft of drive motor I 41 is connected to the top of the stirring shaft 5 via a flexible coupling. This flexible coupling buffers vibrations during transmission, providing continuous and stable power for the rotation of the stirring shaft 5. A sealing end cover 6 is rotatably mounted on the outer wall of the bottom end of the stirring shaft 5 via a deep groove ball bearing. The sealing end cover 6 is a stainless steel disc-shaped structure with a rubber sealing ring embedded at its edge. When the lifting seat 4 moves the sealing end cover 6 downward to the top of the emulsification tank 10, the sealing ring fits tightly against the top opening end face of the emulsification tank 10, thereby sealing the emulsification tank 10 and ensuring a vacuum environment inside the tank.

[0034] A connecting ring 73 is fixedly fitted onto the outer wall of the bottom end of the stirring shaft 5 via a flat key. The connecting ring 73 is a stainless steel annular structure. After being connected by the flat key, it is axially fixed with a locking nut to prevent axial displacement of the connecting ring 73 during the rotation of the stirring shaft 5. Multiple stirring blades 7 are uniformly welded to the outer wall of the connecting ring 73 along the circumference. The stirring blades 7 are stainless steel plate structures, with one end fully welded to the outer wall of the connecting ring 73. The weld joint is ground to ensure the connection is firm. The top ends of the multiple stirring blades 7 are jointly welded to a support ring 74. The support ring 74 is a stainless steel annular structure, fitted onto the outer side of the outer wall of the stirring shaft 5, and fully welded to the top end of each stirring blade 7. This connects the top ends of the multiple stirring blades 7 into a whole, improving the connection stability and structural rigidity of the multiple stirring blades 7, and preventing deformation or displacement of the stirring blades 7 during high-speed rotation.

[0035] Each stirring blade 7 has a heat-conducting plate I 71 welded and fixed to its inner sidewall, and a heat-conducting plate II 72 welded and fixed to its bottom end face. Both heat-conducting plates I 71 and II 72 are made of copper alloy plates with excellent thermal conductivity, and the surface of the plates is treated with anti-oxidation. The heat-conducting plates I 71 and the inner sidewall of the stirring blade 7, and the heat-conducting plates II 72 and the bottom end face of the stirring blade 7 are fully welded and fixed to ensure heat transfer efficiency. The installation position of the multiple heat-conducting plates II 72 is adjusted outward in sequence along the radial direction of the stirring shaft 5, and their ends can extend to the bottom edge of the inner wall of the emulsification tank 10, which can completely cover the bottom wall of the emulsification tank 10. The installation height of the multiple heat-conducting plates I 71 is adjusted upward in sequence along the axial direction of the stirring shaft 5, and their ends can extend to the inner sidewall of the emulsification tank 10, which can completely cover the inner wall of the emulsification tank 10, realizing all-round, dead-angle-free heat exchange of the paste inside the emulsification tank 10.

[0036] The internal structure of the stirring blade 7 has independent water inlet and drainage channels along its length. The inner walls of these channels are smoothed to reduce resistance to medium flow. The internal structure of the stirring shaft 5 also has independent water inlet and drainage channels along its axial direction. These channels are connected to the water inlet and drainage channels of each stirring blade 7, with welded seals at the connections to prevent leakage. Both heat-conducting plates I 71 and II 72 have internal medium flow channels. The water inlet ends of heat-conducting plates I 71 and II 72 are connected to the water inlet channels on the stirring blades 7 via corrugated metal pipes. The drainage ends of heat-conducting plates I 71 and II 72 are connected to the drainage channels on the stirring blades 7 via metal pipes. These metal pipes are designed to accommodate the rotation of the stirring blades 7 while ensuring a leak-proof seal. Rotary joint I51 and rotary joint II52 are respectively mounted on the outer wall of the top end of the stirring shaft 5 through bearings. Rotary joint I51 is connected to the drainage channel inside the stirring shaft 5, and rotary joint II52 is connected to the water inlet channel inside the stirring shaft 5. The addition of the rotary joints enables the external cold and hot media to be continuously transported during the rotation of the stirring shaft 5. External cold and hot media can be connected to rotary joint II52 through pipes, enter the water inlet channel of the stirring shaft 5 through rotary joint II52, and then be distributed to the water inlet channels of each stirring blade 7. Finally, they are transported through metal pipes to the media flow channels inside the heat-conducting plate I71 and heat-conducting plate II72. After heat exchange with the paste, the media flows back to the drainage channel of the stirring blade 7 through the drainage end of heat-conducting plate I71 and heat-conducting plate II72, and then is discharged from rotary joint I51 through the drainage channel of stirring shaft 5. This achieves precise temperature control of the paste in the emulsification tank 10. Moreover, the heat exchange components are directly inserted into the inside of the paste, which greatly improves the heat exchange efficiency and ensures that the temperature of the paste is uniform throughout the tank.

[0037] A spiral conveying rod I 54 is fixed to the outer wall of the bottom end of the mixing shaft 5 via a flat key connection. The blades of the spiral conveying rod I 54 are made of stainless steel and rotate synchronously with the mixing shaft 5. A guide sleeve 55 is also fitted onto the outer wall of the mixing shaft 5. The guide sleeve 55 is a stainless steel cylindrical structure located outside the spiral conveying rod I 54, with a uniform gap between it and the spiral conveying rod I 54. It guides the delivery of the paste during the rotation of the spiral conveying rod I 54 and prevents the paste from spreading in an irregular direction. Multiple connecting supports 57 are uniformly welded to the top end face of the guide sleeve 55 along the circumference. The connecting supports 57 are stainless steel cylindrical structures, and their bottom ends are fully welded to the guide sleeve 55. A dispersion guide hood 53 is also rotatably fitted onto the outer wall of the mixing shaft 5 via a deep groove ball bearing. The dispersion guide hood 53 is a stainless steel conical structure, and its bottom end face is fully welded to the top ends of all the connecting supports 57, achieving a firm connection between the dispersion guide hood 53 and the guide sleeve 55. A uniform gap is left between the inner wall of the dispersing guide hood 53 and the outer wall of the guide sleeve 55, forming multiple circumferentially distributed discharge ports 58. A suspension support 56 is welded and fixed to the bottom end face of the sealing end cap 6 at a position corresponding to the dispersing guide hood 53. The suspension support 56 is a stainless steel cylindrical structure, and its bottom end is fully welded and fixed to the top end face of the dispersing guide hood 53 to achieve auxiliary fixation of the dispersing guide hood 53, further improving its structural stability and preventing it from shifting under the impact of the paste. When the stirring main shaft 5 rotates, it drives the spiral conveying rod I 54 to rotate synchronously, conveying the paste at the bottom of the emulsion tank 10 upward. After the paste is discharged through the discharge port 58, it spreads evenly in all directions under the guiding action of the dispersing guide hood 53, and works with the stirring blade 7 to achieve uniform mixing of the paste.

[0038] A feed conduit 8 is vertically rotatably installed at the center of the top end face of the lifting seat 4 and the sealing end cover 6. The feed conduit 8 is a hollow stainless steel tube, and it is connected to the lifting seat 4 and the sealing end cover 6 by deep groove ball bearings. Oil seals are installed at the bearings to ensure sealing performance and enable flexible rotation of the feed conduit 8. The output shaft of the drive motor II 42 inside the lifting seat 4 is connected to the top end of the feed conduit 8 via a synchronous pulley. A protective cover is installed on the outside of the synchronous pulley to prevent foreign objects from being drawn in and to provide stable power for the rotation of the feed conduit 8. The top end of the feed conduit 8 is fixedly connected to a storage tank 12 via a flange structure. A sealing gasket is installed at the flange connection. The storage tank 12 is a stainless steel cylindrical structure with an open top and a sealing cover on the top. It is used to store raw materials such as powders, peptide solutions, and heat-sensitive components. Its bottom is connected to the inside of the feed conduit 8 to achieve smooth material transportation.

[0039] A dispersing disc 81 is welded and fixed to the bottom end of the feed conduit 8. The dispersing disc 81 is a stainless steel disc-shaped structure. Multiple guide teeth 811 are integrally formed on the side of the disc away from the feed conduit 8. The multiple guide teeth 811 are evenly distributed around the circumference of the dispersing disc 81 and arranged radially. The surface of the guide teeth 811 is smoothed to reduce friction with the material. A discharge hood 82 is also welded and fixed to the bottom outer wall of the feed conduit 8. The discharge hood 82 is a stainless steel frustum-shaped structure. It is located on top of the dispersing disc 81 and has a uniform gap with the dispersing disc 81. Multiple discharge ports are evenly distributed around the circumference on the bottom side wall of the feed conduit 8 and the side wall of the discharge hood 82. The inner wall of the discharge port is smoothed to prevent material residue. After the raw materials in the storage tank 12 are transported to the bottom through the feed pipe 8, they are discharged outward through the discharge port of the feed pipe 8 and the discharge hood 82 under the centrifugal action of the rotating feed pipe 8. The discharged raw materials are then dispersed a second time by the guide teeth 811 on the dispersion plate 81, so that the raw materials enter the emulsification tank 10 in a uniform state and mix with the paste, effectively preventing the raw materials from clumping.

[0040] A support base 9 is welded and fixed to one side of the frame 1. The support base 9 is a frame structure formed by welding steel sections. Its top is at the same level as the top of the frame 1, and its bottom is also welded with foot plates and fixed to the ground with expansion bolts to ensure structural stability. Rotating spindles 13 are horizontally mounted on both the side of the support base 9 near the frame 1 and the side of the frame 1 near the support base 9. The rotating spindles 13 are hollow stainless steel shafts, which are fitted with deep groove ball bearings to the support base 9 and the frame 1, with seals installed at the bearings. The axes of the two rotating spindles 13 are collinear, and their opposite ends are welded and fixed to the center of the two side ends of the emulsifying tank 10, making the emulsifying tank 10 coaxial with the stirring spindle 5. The emulsifying tank 10 is a stainless steel cylindrical sealed tank, formed by welding stainless steel plates. The tank has a uniform wall thickness, good sealing performance, and corrosion resistance. An insulation layer can be added to the outside of the tank as needed.

[0041] A worm gear 14, made of cast steel, is fixedly mounted on the outer wall of the rotating main shaft 13 located within the support base 9 via a flat key. It is axially fixed to the rotating main shaft 13 by a locking nut. A worm 15 is also vertically mounted inside the support base 9, meshing with the worm gear 14. The top end of the worm 15 extends to the outside of the support base 9 and is welded with a handwheel for easy manual rotation. Rotating the worm 15, through the meshing transmission of the worm gear 14 and worm 15, drives the worm gear 14 and the rotating main shaft 13 to rotate synchronously, thereby causing the emulsifying tank 10 to rotate around the axis of the rotating main shaft 13. This allows for angle adjustment of the emulsifying tank 10, facilitating the unloading of the paste and cleaning of the tank interior. The transmission structure of the worm gear 14 and worm 15 has a self-locking function, allowing the emulsifying tank 10 to stably remain at any rotation angle.

[0042] A sampling device 11 is detachably installed on the outer wall of the emulsification tank 10. The sampling device 11 includes a sampling cylinder 111, which is a hollow cylindrical structure made of stainless steel. One end of the sampling cylinder 111 is inserted into the rotating main shaft 13 inside the support base 9. The rotating main shaft 13 has an axially oriented through hole inside, which communicates with the interior of the emulsification tank 10 and the interior of the sampling cylinder 111, ensuring the connectivity between the sampling cylinder 111 and the interior of the emulsification tank 10, thus enabling the sampling of the paste. A spiral conveying rod II 112 is axially rotatably installed inside the sampling cylinder 111. The spiral conveying rod II 112 is made of stainless steel, with one end extending to the outside of the sampling cylinder 111 and welded with a handwheel for easy operation by the operator. When the spiral conveyor rod II 112 rotates, the paste in the emulsification tank 10 is sucked into the sampling cylinder 111 by the pushing action of the spiral blades, so as to realize the quantitative sampling of the paste. The other end of the sampling cylinder 111 is provided with a discharge port and a sealing plug for easy sample removal.

[0043] A positioning collar 113 is welded and fixed to the outer wall of the sampling cylinder 111. The positioning collar 113 is a stainless steel annular structure and is fully welded to the sampling cylinder 111. Multiple limiting pins 114 are evenly welded and fixed circumferentially on the end face of the positioning collar 113 near the rotating main shaft 13. The limiting pins 114 are stainless steel round pins. The end face of the rotating main shaft 13 has pin holes that are adapted to the limiting pins 114. The limiting pins 114 are inserted into the pin holes on the rotating main shaft 13 to achieve positioning and fixation between the sampling cylinder 111 and the rotating main shaft 13, preventing the sampling cylinder 111 from shifting axially or circumferentially during the sampling process and ensuring the smooth progress of the sampling operation.

[0044] A valve plate 16 is vertically slidably mounted on the outer wall of the emulsification tank 10. A stainless steel slide rail is welded and fixed to the outer wall of the emulsification tank 10. The valve plate 16 slides up and down through a sliding engagement with the slide rail. The sliding engagement between the sliding engagement and the slide rail is lubricated to reduce sliding resistance. A stainless steel dust cover is fastened to the outside of the stainless steel slide rail. The dust cover is sealed and fixed to the slide rail. A sliding engagement gap is reserved between the sliding engagement and the dust cover, and a rubber dustproof strip is embedded in the gap to prevent dust and paste debris from entering the mating surface. A plug-in port 115 is provided on the top end face of the rotating main shaft 13 inside the support base 9. The plug-in port 115 is connected to the through hole inside the rotating main shaft 13. The bottom end of the valve plate 16 can be plugged into the plug-in port 115 to seal the through hole inside the rotating main shaft 13, thereby controlling the opening and closing of the connection between the rotating main shaft 13 and the sampling cylinder 111. A lead screw 17, made of stainless steel, is vertically mounted on the outer wall of the emulsification tank 10 via a bearing. A threaded hole is located in the middle of a valve plate 16, which is threaded onto the bottom outer wall of the lead screw 17. A handwheel is welded to the top of the lead screw 17 for easy rotation by the operator. Rotating the lead screw 17 causes the valve plate 16 to slide up and down along the axial direction of the lead screw 17 via threaded transmission, enabling the valve plate 16 to connect and disconnect from the insertion port 115. This allows for precise control of the sampling channel's opening and closing, ensuring a vacuum sterile environment inside the emulsification tank 10 during sampling. A telescopic stainless steel dust cover is fitted around the lead screw 17, with both ends of the dust cover sealed and fixed to the outer wall of the emulsification tank 10 and the outer wall of the valve plate 16, respectively.

[0045] A programmable logic controller (PLC) is also fixedly connected inside the lifting seat 4. The PLC is electrically connected to drive motor I 41, drive motor II 42, and hydraulic cylinder 2. The PLC is used to control the start and stop and speed adjustment of drive motor I 41 and drive motor II 42, and at the same time control the extension and retraction of the piston rod of hydraulic cylinder 2, so as to realize the timing coordination and action coordination of each actuator. The external vacuum unit and temperature control unit are both connected to the PLC for signal control, and the vacuum degree and the temperature inside the tank are uniformly regulated by the PLC.

[0046] When this device is in operation, the lifting seat 4 is first moved upward by the hydraulic cylinder 2 to open the sealing end cover 6 of the emulsification tank 10. The prepared oil phase and water phase materials are then added into the emulsification tank 10. Subsequently, the lifting seat 4 is moved downward by the hydraulic cylinder 2 to seal the sealing end cover 6 with the emulsification tank 10. An external vacuum unit is used to evacuate the inside of the emulsification tank 10. At the same time, a heat medium is introduced into the water inlet channel of the stirring shaft 5 and the stirring blades 7 through the rotary joint II 52. The constant temperature inside the tank is achieved through the heat-conducting plates I 71 and II 72. The drive motor I 41 is started to drive the stirring shaft 5, the stirring blades 7 and the spiral conveyor I 54 to rotate. The stirring blades 7 scrape the walls and stir, while the spiral conveyor I 54 conveys the material from the bottom of the tank upward. After being discharged through the discharge port 58, the material is guided and diffused by the dispersion guide hood 53 to achieve high shear homogeneous emulsification of the material and form a lip glaze base.

[0047] After emulsification, the high-shear mode is turned off, and the drive motor I41 drives the stirring blade 7 to rotate at low speed. At the same time, the cooling medium is introduced through the rotary joint II52, and heat exchange with the paste through the heat-conducting plates I71 and II72 to achieve stable cooling of the paste. The vacuum unit continuously evacuates the vacuum to complete the cooling, defoaming, and deoxygenation of the paste. After the paste temperature drops to the set value, the peptide solution and heat-sensitive components are added to the storage tank 12. The drive motor II42 is started to drive the feed pipe 8 to rotate at low speed. The material is discharged through the feed pipe 8 and the outlet of the discharge hood 82. After being dispersed by the dispersing plate 81 and the guide teeth 811, it is smoothly injected into the emulsification tank 10. The stirring blade 7 continues to rotate at low speed to achieve flexible physical mixing and avoid damaging the peptide structure.

[0048] If sampling is required during the mixing process, rotate the screw 17 to move the valve plate 16 upward, open the plug port 115, rotate the spiral conveyor rod II 112 to suck the paste in the tank into the sampling cylinder 111. After sampling is completed, rotate the screw 17 in the opposite direction to block the plug port 115 with the valve plate 16 to ensure a vacuum sterile environment inside the tank.

[0049] After all mixing processes are completed, the vacuum inside the tank is released. Hydraulic cylinder 2 drives the lifting seat 4 to move upward and open the sealing end cover 6. The worm gear 15 rotates, driving the worm wheel 14 and the main shaft 13 to rotate, causing the emulsification tank 10 to flip around the main shaft 13, completing the unloading of the paste. After unloading, the emulsification tank 10 is flipped in the opposite direction, ready for the next batch preparation. Throughout the entire process, the drive motor I 41 and drive motor II 42 can independently adjust their speeds to meet the operational requirements of different stages of the process. The heat exchange system achieves precise temperature control inside the tank, and the various sealing structures ensure a vacuum sterile environment inside the tank. The coordinated operation of all components enables the efficient and stable preparation of the composite bioactive peptide lip gloss paste.

[0050] However, as is well known to those skilled in the art, the working principles and wiring methods of drive motor I 41 and drive motor II 42 are conventional methods or common knowledge, and will not be described in detail here. Those skilled in the art can make any selections according to their needs or convenience.

[0051] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention and are not intended to limit it. Although the present invention has been described in detail with reference to preferred embodiments, those skilled in the art should understand that modifications or equivalent substitutions can be made to the technical solutions of the present invention without departing from the spirit and scope of the present invention, and all such modifications or substitutions should be covered within the scope of the claims of the present invention.

Claims

1. A process for preparing a lip gloss containing a complex bioactive peptide, characterized in that, This includes the following steps performed sequentially: S1. Pre-preparation of color paste: The oil and color powder are mixed in the formula ratio and then subjected to multiple high-intensity grinding processes to completely coat the surface of the color powder with oil, thus obtaining a pre-prepared color paste. S2, Matrix melting: The structural lipid, synthetic oil and the pre-made color paste are mixed and heated to completely melt to form an oil phase, and deionized water and humectant are heated and dissolved to form an aqueous phase; S3. Homogenization and emulsification: The oil phase and water phase are mixed under vacuum and constant temperature conditions, and the emulsification is carried out by high shear homogenization and frame-type wall scraping and stirring to form a lip gloss base with a network structure. S4. Vacuum cooling and degassing: Stop high shear homogenization, maintain high vacuum in the system and keep low-speed wall scraping and stirring, and cool the paste steadily to below the inactivation critical point of the complex bioactive peptides to achieve deep degassing of the paste and deoxygenation of the system. S5. Non-destructive encapsulation of peptides: At a temperature below the inactivation critical point, the composite bioactive peptide solution and heat-sensitive components are injected into the ointment through a closed feeding system. Only a low speed is used to perform flexible physical mixing of the ointment to avoid mechanical shearing that could damage the molecular structure of the composite bioactive peptides. S6. Curing and Filling: Release the system vacuum, transport the evenly mixed paste to a sealed curing tank for static curing, and then fill the paste in a light-proof and aseptic manner to avoid oxidation and inactivation of the complex bioactive peptides.

2. An emulsification device for preparing lip gloss with a complex bioactive peptide, applied to the lip gloss preparation process of the complex bioactive peptide described in claim 1, characterized in that, include: A frame (1) is vertically slidably connected to a lifting seat (4) at the top of the frame (1). A stirring main shaft (5) is vertically penetrated and rotatably connected to the bottom of the lifting seat (4). A sealing end cap (6) is rotatably sleeved on the outer wall of the bottom end of the stirring main shaft (5). A connecting ring (73) is fixedly sleeved on the bottom end of the stirring main shaft (5). Multiple stirring blades (7) are circumferentially fixed to the outer wall of the connecting ring (73). A support ring (74) is fixedly connected to the top of the multiple stirring blades (7). The support ring (74) is sleeved on the outside of the stirring main shaft (5). Support base (9), the support base (9) is fixed to one side of the frame (1), and an emulsifying tank (10) is rotatably connected between the support base (9) and the frame (1). The emulsifying tank (10) is coaxially arranged with the stirring spindle (5), and the sealing end cap (6) is adapted to the top opening of the emulsifying tank (10) to achieve vacuum sealing. Sampling device (11), the sampling device (11) is detachably connected to the outer wall of the emulsification tank (10), the sampling device (11) includes a sampling cylinder (111), the sampling cylinder (111) is connected to the emulsification tank (10), a spiral conveying rod II (112) is axially penetrated and rotatably connected inside the sampling cylinder (111), when the spiral conveying rod II (112) rotates, it sucks up and pushes the paste in the emulsification tank (10) into the sampling cylinder (111); Feeding conduit (8), which is vertically penetrating and rotatably connected to lifting seat (4) and sealing end cap (6), a storage tank (12) is fixedly connected to the top of the feeding conduit (8), the storage tank (12) is connected to the inside of the feeding conduit (8), a dispersing disc (81) is fixedly connected to the bottom of the feeding conduit (8), and a discharge hood (82) is fixedly fitted on the outer wall of the bottom of the feeding conduit (8), the discharge hood (82) is located on the top of the dispersing disc (81), and discharge ports are opened on the side walls of the feeding conduit (8) and the side of the dispersing disc (81) away from the feeding conduit (8) is integrally formed with multiple guide teeth (811). Drive motor I (41) and drive motor II (42) are both fixed inside the lifting seat (4). The output shaft of drive motor I (41) is connected to the stirring main shaft (5) to drive it to rotate. The output shaft of drive motor II (42) is connected to the feed pipe (8) to drive it to rotate. After the material in the storage tank (12) is discharged through the feed pipe (8) and the discharge port of the discharge hood (82), it is dispersed and injected into the emulsification tank (10) through the dispersion plate (81) and the guide tooth (811).

3. The emulsifying apparatus for preparing lip gloss with composite bioactive peptides according to claim 2, characterized in that, The top of the frame (1) is vertically penetrated and fixedly connected to a hydraulic cylinder (2). The top of the frame (1) is vertically penetrated and slidably connected to a guide column (3). The top of the guide column (3) and the piston rod of the hydraulic cylinder (2) are both fixedly connected to the bottom wall of the lifting seat (4). The piston rod of the hydraulic cylinder (2) extends and retracts to drive the lifting seat (4) to slide along the axial direction of the guide column (3), thereby causing the sealing end cap (6) to fit or separate from the top opening of the emulsion tank (10).

4. The emulsifying apparatus for preparing lip gloss with composite bioactive peptides according to claim 3, characterized in that, The supporting base (9) and the frame (1) are horizontally connected to a rotating spindle (13) on opposite sides. The two ends of the emulsifying tank (10) are fixedly connected to the opposite ends of the two rotating spindles (13). The rotating spindle (13) located in the supporting base (9) is a hollow structure and is connected to the interior of the emulsifying tank (10). A worm wheel (14) is fixedly sleeved on the outer wall of the rotating spindle (13). A worm (15) is horizontally connected to the supporting base (9). The worm (15) meshes with the worm wheel (14). Rotating the worm (15) drives the rotating spindle (13) to rotate through the worm wheel (14), thereby driving the emulsifying tank (10) to rotate around the axis of the rotating spindle (13).

5. The emulsifying apparatus for preparing lip gloss with composite bioactive peptides according to claim 4, characterized in that, The sampling cylinder (111) is inserted into the rotating main shaft (13) of the support base (9) at one end away from the emulsification tank (10). A valve plate (16) is vertically slidably connected to the outer wall of the emulsification tank (10). A plug-in port (115) is opened at the top of the rotating main shaft (13). The bottom end of the valve plate (16) is adapted to the plug-in port (115) to realize the opening and closing of the sampling channel. A lead screw (17) is vertically rotatably connected to the outer wall of the emulsification tank (10). The valve plate (16) is threaded onto the bottom end of the lead screw (17). Rotating the lead screw (17) drives the valve plate (16) to slide along the axial direction of the lead screw (17) to realize the plug-in or separation of the valve plate (16) and the plug-in port (115).

6. The emulsifying apparatus for preparing lip gloss with composite bioactive peptides according to claim 5, characterized in that, The outer wall of the sampling cylinder (111) is fixedly fitted with a positioning collar (113). A plurality of limiting pins (114) are circumferentially fixed to one side of the positioning collar (113) near the rotating main shaft (13). The limiting pins (114) are inserted into the end of the rotating main shaft (13) to realize the circumferential and axial positioning of the sampling cylinder (111) and the rotating main shaft (13).

7. The emulsifying apparatus for preparing lip gloss paste with composite bioactive peptides according to any one of claims 2 to 6, characterized in that, The bottom end of the stirring shaft (5) is fixedly fitted with a spiral conveying rod I (54). The outer wall of the stirring shaft (5) is fitted with a guide sleeve (55). The guide sleeve (55) is located outside the spiral conveying rod I (54). The top of the guide sleeve (55) is circumferentially fixed with multiple connecting pillars (57). The outer wall of the stirring shaft (5) is rotatably fitted with a dispersion guide hood (53). The bottom wall of the dispersion guide hood (53) is fixedly connected to the top of multiple connecting pillars (57). Multiple discharge ports (58) are formed between the inner wall of the dispersion guide hood (53) and the outer wall of the guide sleeve (55). The bottom wall of the sealing end cap (6) is fixedly connected to the top wall of the dispersion guide hood (53) with a suspension pillar (56). The rotation of the stirring shaft (5) drives the spiral conveying rod I (54) to convey the paste at the bottom of the emulsion tank (10) upward. After being discharged through the discharge ports (58), it is guided by the dispersion guide hood (53) to diffuse evenly in all directions.

8. The emulsifying apparatus for preparing lip gloss with composite bioactive peptides according to claim 2, characterized in that, Each of the stirring blades (7) has a heat-conducting plate I (71) fixedly connected to its inner sidewall, and a heat-conducting plate II (72) fixedly connected to its bottom wall. Both the stirring blades (7) and the stirring shaft (5) have water inlet channels and drainage channels. The water inlet channels and drainage channels of the stirring blades (7) are connected to the water inlet channels and drainage channels of the stirring shaft (5) respectively. The water inlet ends of the heat-conducting plates I (71) and II (72) are connected to the water inlet channels of the stirring blades (7) through pipes. The drainage ends of the heat-conducting plates I (71) and II (72) are connected to the drainage channels of the stirring blades (7) through pipes.

9. The emulsifying apparatus for preparing lip gloss with composite bioactive peptides according to claim 8, characterized in that, The top of the stirring spindle (5) is rotatably connected to a rotary joint I (51) and a rotary joint II (52). The rotary joint I (51) is connected to the drainage channel of the stirring spindle (5), and the rotary joint II (52) is connected to the water inlet channel of the stirring spindle (5). The cold and hot media enter the water inlet channels of the stirring spindle (5) and the stirring blade (7) through the rotary joint II (52), flow through the heat-conducting plate I (71) and the heat-conducting plate II (72) to exchange heat with the paste, and then are discharged through the drainage channel and the rotary joint I (51).

10. The emulsifying apparatus for preparing lip gloss with composite bioactive peptides according to claim 9, characterized in that, The positions of the multiple heat-conducting plates II (72) are adjusted outward in sequence along the radial direction of the stirring shaft (5) and completely cover the bottom wall of the emulsification tank (10). The heights of the multiple heat-conducting plates I (71) are adjusted upward in sequence along the axial direction of the stirring shaft (5) and completely cover the inner wall of the emulsification tank (10).

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