A respiratory tract drug delivery device and method based on atomization technology
By continuously monitoring and adaptively adjusting the output of the nebulizer, the problem of reverse drug expulsion during the exhalation phase is solved, achieving efficient drug utilization and stable therapeutic effects.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- CHONGQING XIANGHUA PHARMACEUTICAL CO LTD
- Filing Date
- 2026-03-10
- Publication Date
- 2026-06-09
AI Technical Summary
Traditional nebulizer-based respiratory drug delivery devices are prone to reverse flow of medication during the patient's exhalation phase, leading to drug loss, increased economic burden, and reduced treatment efficiency.
A respiratory drug delivery device based on nebulization technology was designed. Through the guide component and the control component, the output of the nebulization device can be continuously detected and adaptively controlled to avoid drug loss.
It effectively reduces drug waste, improves treatment efficiency, ensures that drugs mainly enter the respiratory tract, and enhances treatment effects.
Smart Images
Figure CN122163946A_ABST
Abstract
Description
Technical Field
[0001] This invention relates to the field of drug delivery device technology, and in particular to a respiratory drug delivery device and method based on nebulization technology. Background Technology
[0002] Existing respiratory drug delivery devices are mainly divided into four categories: pressurized metered-dose inhalers, dry powder inhalers, soft fog inhalers, and nebulizers. Nebulizers convert liquid drugs into aerosols through compressed gas, ultrasound, or vibrating screens, which patients can inhale with calm breathing. They are easy to operate and can deliver drugs directly to the lesion site through nebulization technology, achieving high local drug concentration and rapid onset of action. Compared with other inhalation devices, respiratory drug delivery devices based on nebulization technology have lower requirements for the patient's breathing cooperation, making them especially suitable for infants, the elderly, or critically ill patients. They can effectively nebulize complex macromolecular drugs such as proteins and nucleic acids, providing a core means of daily treatment for chronic respiratory diseases such as asthma and chronic obstructive pulmonary disease. They are also a key route of drug delivery in the treatment of acute or severe respiratory infections such as respiratory tract infections and pulmonary fibrosis. However, traditional nebulizer-based respiratory drug delivery devices continuously convert liquid medication into aerosols during operation. During a patient's normal respiratory cycle, the airflow during exhalation will expel at least 50% of the drug mist generated by the device back into the outside air. Moreover, some patients, especially children, are prone to crying, which can cause the drug delivery element to fall off. In this case, the nebulizer will continue to work, resulting in a large amount of expensive medication being lost before it is inhaled into the lungs. This not only significantly increases the patient's financial burden but also greatly reduces the actual amount of medication entering the respiratory tract, leading to unstable treatment effects and even requiring extended treatment time to make up for the loss, thereby reducing the overall treatment efficiency. Summary of the Invention
[0003] The purpose of this invention is to provide a respiratory drug delivery device and method based on nebulization technology, which can continuously detect the output of the nebulization device through a set component, and then adaptively adjust the actual output according to the detection results, so as to avoid a large amount of drug loss and waste and improve the overall treatment efficiency.
[0004] To achieve the above objectives, the present invention provides a respiratory drug delivery device and method based on nebulization technology, including a mask body and side buckle frames, two of the side buckle frames being fixedly installed on both sides of the mask body, and also including a guide assembly; The guiding assembly includes a slot plate, a nose cover, a locking platform, locking teeth, an interconnecting component, an adjusting component, and an external component. The slot plate is fixedly installed on the mask body. The locking platforms are fixed on both sides of the nose cover. The bottom of the nose cover has a communicating inner groove. The locking platforms match the locking grooves on the slot plate. The locking teeth are fixedly installed on the slot plate and match the tooth grooves on the locking platforms. The interconnecting component is connected to the mask body and is used to control the corresponding communication relationship between the mask body and the nose cover. The adjusting component is connected to the mask body and is used to adjust the input of the nebulizer. The external component is connected to the output end of an external nebulizer and is used to guide the liquid medicine discharged from the nebulizer.
[0005] The interconnection component includes an interconnection frame, a connecting pipe, and a control component. The interconnection frame is fixedly installed on the mask body. The connecting pipe is connected to the interconnection frame and is fixedly installed on the side of the mask body near the nose cover. The nose cover has a corresponding insertion hole that cooperates with the connecting pipe. The control component is connected to the mask body and is used to regulate the communication relationship between the interconnection frame and the mask body.
[0006] The control component includes a receiving frame, a flow control frame, a sliding cut-off plate, a unidirectional conduction component, and a self-adjusting component. The receiving frame is fixedly installed on the mask body, and the receiving frame is connected to the interconnection frame through the unidirectional conduction component. The flow control frame is fixedly installed on one side of the receiving frame. The sliding cut-off plate is slidably installed on the flow control frame. The self-adjusting component is connected to the receiving frame and is used to drive and adjust the sliding cut-off plate according to the output of the medicine in the receiving frame.
[0007] The external component includes an internally threaded cylinder, a threaded connector, and an access tube. The internally threaded cylinder is fixedly installed on one side of the flow control frame. The threaded connector is threadedly connected to the internally threaded cylinder. The access tube is fixedly installed on one side of the threaded connector and connected to the output end of the external atomizer.
[0008] The control component includes an embedded hole block and a threaded plug. One side of the embedded hole block is connected to the interconnect frame, and the other side of the embedded hole block is connected to the mask body. The threaded plug is threadedly connected to the embedded hole block and passes through the embedded hole block.
[0009] The unidirectional guiding component includes a conical groove guide cylinder and a lightweight plug bead. One side of the conical groove guide cylinder is connected to the interconnection frame, and the other side of the conical groove guide cylinder is connected to the receiving frame. The lightweight plug bead is disposed inside the conical groove guide cylinder.
[0010] The self-adjusting component includes a limiting card holder, a mounting bracket, a sliding block, a sensing module, and a tightening bolt. The limiting card holder is fixedly installed on one side of the receiving rack. The mounting bracket is inserted into one side of the receiving rack and cooperates with the limiting card holder. The sliding block is slidably installed on the side of the mounting bracket near the receiving rack. The sensing module is installed on the side of the sliding block near the receiving rack. The tightening bolt is rotatably connected to the sliding block and threadedly connected to the mounting bracket.
[0011] The self-adjusting component further includes an adapter plate, an adjusting screw, a self-controlled motor, and an electronic control module. The adapter plate engages with the drive slot provided on the sliding section plate and is slidably mounted on the mounting frame. The adjusting screw is threadedly connected to the adapter plate and rotatably mounted on the mounting frame. The output end of the self-controlled motor is connected to the adjusting screw, and the self-controlled motor is fixedly mounted on one side of the mounting frame. The electronic control module is electrically connected to the self-controlled motor and to the sensing module, and is mounted on one side of the mounting frame.
[0012] The guiding assembly further includes a discharge frame, a one-way control frame, a discharge pipe, and an intercepting rotating frame. The discharge frame is fixedly installed on one side of the mask body; the one-way control frame is fixedly installed on one side of the discharge frame; the discharge pipe is fixedly installed at the bottom of the one-way control frame; and the intercepting rotating frame is rotatably installed inside the one-way control frame.
[0013] One method for administering medication via the respiratory tract using nebulization technology, employing the aforementioned nebulization-based respiratory medication delivery device, includes the following steps. Select a nose cover of appropriate size according to the patient's nose size, and install the nose cover on the card slot plate by using the card platform set on the nose cover. When the card platform is inserted and assembled, the card teeth set on the card slot plate limit the card platform to ensure the stability of the nose cover after installation. The mask body is placed over the patient's mouth using straps on the side buckle frame, while ensuring that the nose cover fits the patient's nose accordingly. The atomized medicine output by the atomizer is then guided by an external component, and then introduced into the communicating inner groove of the nose cover or the mask body through the control component and the interconnection component. Patients can use the nose cover and the mask body to introduce atomized medication through the nasal cavity or mouth. During the introduction process, the control component will analyze and judge the introduction of medication based on the concentration of the introduced medication and related data. Based on the analysis and judgment of the corresponding drug infusion situation, the control component will adjust the output atomized drug solution accordingly or directly cut off the continuous output of the atomized drug solution.
[0014] This invention discloses a respiratory drug delivery device and method based on nebulization technology. In actual operation, a nasal sleeve of appropriate size is first selected according to the patient's nose size. The nasal sleeve is then installed on a slotted plate using a locking mechanism on the nasal sleeve. During insertion and assembly, the locking mechanism is limited by locking teeth on the slotted plate to ensure stability after installation. A mask body is then placed over the patient's mouth using straps on the side buckle frame, ensuring a proper fit between the nasal sleeve and the patient's nose. The nebulized medication output from the nebulizer is then guided through an external component and atomized via a control component and an interconnecting component. The medication is introduced into the communicating inner groove of the nasal sleeve or into the main body of the mask. The patient can use the nasal sleeve and the main body of the mask to introduce the nebulized medication through the nasal cavity or mouth. During the introduction process, the control component analyzes and judges the medication introduction based on the concentration of the introduced medication and related data. Based on the analysis and judgment of the medication introduction, the control component will adjust the output of the nebulized medication or directly cut off the continuous output of the nebulized medication. This enables continuous detection of the output of the nebulization device through the provided component, and then adaptive adjustment of the actual output based on the detection results, avoiding a large amount of drug loss and waste, and improving the overall treatment efficiency. Attached Figure Description
[0015] To more clearly illustrate the technical solutions in the embodiments of this application or the prior art, the accompanying drawings used in the description of the embodiments or the prior art will be briefly introduced below.
[0016] Figure 1 This is a schematic diagram of the overall structure of the respiratory drug delivery device based on nebulization technology of the present invention.
[0017] Figure 2 This is a schematic diagram of the installation structure of the discharge rack of the present invention.
[0018] Figure 3 This is a schematic diagram of the interconnection frame and the tapered guide tube of the present invention after being cut open.
[0019] Figure 4 This is the invention Figure 3 Enlarged view of point A.
[0020] Figure 5 This is a top view of the respiratory drug delivery device based on nebulization technology of the present invention.
[0021] Figure 6 This is a schematic diagram of the top section of the card holder of the present invention.
[0022] Figure 7This is a schematic diagram of the nasal cover structure cut open from the side.
[0023] Figure 8 This is a schematic diagram of the structure of the discharge rack and unidirectional control rack of the present invention, cut open from the side.
[0024] Figure 9 This is a schematic diagram of the structure of the interconnection frame of the present invention, cut open from the upper side.
[0025] Figure 10 This is the invention Figure 9 Enlarged view of point B.
[0026] Figure 11 This is a flowchart of the respiratory tract drug delivery method based on nebulization technology of the present invention.
[0027] In the diagram: 101-Mask body, 102-Side buckle frame, 103-Card slot plate, 104-Nose cover, 105-Card platform, 106-Card teeth, 201-Interconnection frame, 202-Connecting pipe, 301-Receiving rack, 302-Flow control frame, 303-Sliding section plate, 401-Internal threaded cylinder, 402-Threaded connector, 403-Access pipe, 501-Embedded hole block, 502-Threaded plug, 601-Conical groove guide cylinder, 602-Lightweight plug bead, 701-Limiting card frame, 702-Card mounting frame, 703-Sliding block, 704-Sensing module, 705-Tightening bolt, 706-Adaptor card plate, 707-Adjusting screw, 708-Self-controlled motor, 709-Electrical control module, 801-Discharge frame, 802-One-way adjustment frame, 803-Discharge pipe, 804-Interception rotating frame; Detailed Implementation
[0028] Embodiments of the present invention are described in detail below, examples of which are illustrated in the accompanying drawings, wherein the same or similar reference numerals denote the same or similar elements or elements having the same or similar functions throughout. The embodiments described below with reference to the accompanying drawings are exemplary and intended to explain the present invention, and should not be construed as limiting the present invention.
[0029] In the description of this invention, it should be understood that "a plurality of" means two or more, unless otherwise explicitly specified.
[0030] Please see Figures 1 to 10This invention provides a respiratory drug delivery device and method based on nebulization technology: It includes a mask body 101, a side buckle frame 102, and a guide assembly. The guide assembly includes a slot plate 103, a nose cover 104, a locking platform 105, locking teeth 106, an interconnecting component, a regulating component, and an external component. The interconnecting component includes an interconnecting frame 201, a connecting pipe 202, and a control component. The regulating component includes a receiving frame 301, a flow control frame 302, a sliding section 303, a unidirectional guiding component, and a self-adjusting component. The external component includes an internally threaded cylinder 401, a threaded connector 402, and an access tube 403. The control component includes an embedded hole block 501 and a threaded plug 502. The unidirectional guiding component includes a conical groove guide cylinder 601 and a lightweight plug bead 602. The self-adjusting component includes a limiting frame 701, a locking frame 702, a sliding block 703, and a sensing module 7. 04 and tightening bolt 705, the self-adjusting component also includes an adapter plate 706, an adjusting screw 707, a self-controlled motor 708 and an electronic control module 709. The aforementioned solution solves the problem that traditional respiratory drug delivery devices based on nebulization technology continuously convert liquid medication into aerosol during operation. However, during a patient's normal respiratory cycle, the airflow during the exhalation phase will expel at least 50% of the drug mist generated by the device back into the outside air. Moreover, some patients, especially children, are prone to crying, which can cause the drug delivery element to fall off. In this case, the nebulizer will continue to work, resulting in a large amount of expensive medication being lost before it is inhaled into the lungs. This not only significantly increases the patient's economic burden but also greatly reduces the actual amount of medication entering the respiratory tract, leading to unstable treatment effects and even requiring extended treatment time to make up for the loss, thereby reducing the overall treatment efficiency.
[0031] Furthermore, the two side buckle brackets 102 are fixedly installed on both sides of the mask body 101, the slot plate 103 is fixedly installed on the mask body 101, the nose cover 104 is fixedly provided with the slot platform 105 on both sides, the bottom of the nose cover 104 is provided with a communicating inner groove, the slot platform 105 matches the slot provided on the slot plate 103, the slot plate 103 is fixedly installed with the slot tooth 106, the slot tooth 106 matches the tooth groove provided on the slot platform 105, the interconnecting component is connected to the mask body 101, and is used to control the corresponding communication relationship between the mask body 101 and the nose cover 104, the regulating component is connected to the mask body 101, and is used to regulate the input of the nebulizer, and the external component is connected to the output end of the external nebulizer, and is used to guide the liquid medicine exported by the nebulizer.
[0032] Specifically, the two side buckle frames 102 are provided with corresponding elastic band mounting holes, so that the mask body 101 can be placed on the corresponding position of the patient's face by installing elastic bands. A corresponding slot plate 103 is provided at the nose bridge of the mask body 101. The slot of the slot plate 103 is adapted to the slot platform 105 on both sides of the nose cover 104. Moreover, the slot plate 103 is also provided with corresponding slot teeth 106 that cooperate with the slots of the slot platform 105 to limit the position of the slot platform 105 after it is attached. The actual nose bridge coverage range of the nose cover 104 can be designed in multiple sizes. Combined with the above-mentioned quick-release structure, it can be better suited for patients with different physical conditions.
[0033] The card slot plate 103, the nasal sleeve 104, and the card platform 105 can all be made of soft rubber material, so that the nasal sleeve 104 can fit better with the patient's nose when it is put on. The bottom of the nasal sleeve 104 is provided with a communicating inner groove, so that the nebulized medicine can be guided through the communicating inner groove, and finally the nebulized medicine can be directly introduced into the patient's nasal cavity. Since the nasal mucosa is rich in blood vessels, the drug is absorbed quickly and can bypass the oropharynx, reducing side effects. Therefore, according to the actual situation, choosing to use nasal targeted drug delivery can greatly improve the treatment effect.
[0034] In actual operation, firstly, a nose cover 104 of appropriate size is selected according to the patient's nose size, and then the nose cover 104 is installed on the slot plate 103 by the locking platform 105 set on the nose cover 104. During the insertion and assembly, the locking platform 105 is limited by the locking teeth 106 set on the slot plate 103 to ensure the stability of the nose cover 104 after installation. The mask body 101 is put on the patient's mouth by the straps set on the side buckle 102, while ensuring that the nose cover 104 can fit the patient's nose accordingly. Then, the nebulized medicine output by the nebulizer is guided by the external component, and then the mist is atomized by the control component and the interconnection component. The nebulized medication is introduced into the communicating inner groove of the nasal sleeve 104 or into the mask body 101. The patient can use the nasal sleeve 104 and the mask body 101 to introduce the nebulized medication through the nasal cavity or mouth. During the introduction process, the control component analyzes and judges the medication introduction based on the concentration of the introduced medication and related data. Based on the analysis and judgment of the medication introduction, the control component will adjust the output of the nebulized medication or directly cut off the continuous output of the nebulized medication. This enables continuous detection of the output of the nebulization device through the provided component, and then adaptive adjustment of the actual output based on the detection results, avoiding a large amount of drug loss and waste, and improving the overall treatment efficiency.
[0035] Furthermore, the interconnect frame 201 is fixedly installed on the mask body 101; the connecting pipe 202 is connected to the interconnect frame 201 and is fixedly installed on the side of the mask body 101 near the nose cover 104, the nose cover 104 is provided with a corresponding insertion hole that cooperates with the connecting pipe 202; the guide control component is connected to the mask body 101 and is used to adjust the communication relationship between the interconnect frame 201 and the mask body 101.
[0036] Furthermore, one side of the embedding hole block 501 is connected to the interconnect frame 201, and the other side of the embedding hole block 501 is connected to the mask body 101; the threaded plug 502 is threadedly connected to the embedding hole block 501 and passes through the embedding hole block 501.
[0037] In this embodiment, the interconnect frame 201 is connected to the connecting pipe 202 installed on the mask body 101. The number of connecting pipes 202 can be determined according to the actual situation. In this solution, there are three connecting pipes 202. Therefore, there are also three insertion holes for the nose cover 104. The three insertion holes of the nose cover 104 are connected to the connecting inner groove. When the nose cover 104 is inserted and fitted through the card plate 105, the three insertion holes of the nose cover 104 will also be inserted and fitted with the three connecting pipes 202 so that the nose cover 104 can be connected to the interconnect frame 201 through the connecting pipes 202.
[0038] The mask body 101 is connected to the interconnect frame 201 through the embedded hole block 501. The threaded through hole provided by the embedded hole block 501 is adapted to the threaded plug 502. When the patient needs nasal targeted drug delivery, the threaded plug 502 will be installed on the embedded hole block 501, thereby blocking the threaded through hole provided by the embedded hole block 501. At this time, the nebulized drug solution introduced into the interconnect frame 201 can only enter the communicating inner groove of the nasal sleeve 104 through the communicating pipe 202, and then the subsequent nasal drug delivery is completed through the nasal sleeve 104. If the patient has no special needs, that is, the drug can be continuously delivered through the mouth and nose, the operator can unscrew the threaded plug 502 when putting on the mask body 101, so that the mask body 101 can maintain communication with the interconnect frame 201 through the threaded through hole provided by the embedded hole block 501, thereby completing the subsequent simultaneous oral and nasal drug delivery.
[0039] Furthermore, the receiving frame 301 is fixedly installed on the mask body 101, and the receiving frame 301 is connected to the interconnection frame 201 through the unidirectional conduction component; the flow control frame 302 is fixedly installed on one side of the receiving frame 301; the sliding cut-off plate 303 is slidably installed on the flow control frame 302; the self-adjusting component is connected to the receiving frame 301 and is used to drive and adjust the sliding cut-off plate 303 according to the output of the medicine in the receiving frame 301.
[0040] Furthermore, one side of the conical groove guide tube 601 is connected to the interconnect frame 201, and the other side of the conical groove guide tube 601 is connected to the receiving frame 301; the lightweight plug bead 602 is disposed inside the conical groove guide tube 601.
[0041] In this embodiment, the receiving rack 301 is connected to the interconnecting rack 201 via the provided conical groove guide tube 601. The number of conical groove guide tubes 601 and lightweight plug beads 602 installed can be determined according to actual conditions. In this solution, a total of three sets of conical groove guide tubes 601 and lightweight plug beads 602 are provided. The lightweight plug beads 602 match the bottom conical groove provided inside the conical groove guide tube 601. When the atomized medicine is continuously introduced, the lightweight plug beads 602 will be pushed out of the conical groove at the bottom of the conical groove guide tube 601 by the atomized medicine. At this time, the atomized medicine can be introduced into the interconnecting rack 201 through the slot at the top of the conical groove guide tube 601. Inside the frame 201, when the patient exhales, the lightweight bead 602 is pushed into the conical groove at the bottom of the conical guide tube 601 by the airflow generated by exhalation. This prevents the exhaled gas from entering the receiving frame 301 from the conical guide tube 601, thus achieving one-way outflow and preventing the patient's exhaled gas from flowing back into the receiving frame 301 and subsequent drug delivery tubing. The lightweight bead 602 has a certain mass, but its overall mass is relatively light, so that the weight of the lightweight bead 602 can ensure that the conical guide tube 601 is quickly blocked during exhalation. At the same time, it can also prevent the lightweight bead 602 from being too heavy and causing the nebulized liquid to not be able to be delivered normally.
[0042] It should be noted that if the patient uses nasal targeted drug delivery, that is, the atomized drug is absorbed through the nasal cavity and then exhaled through the mouth, the mask body 101 will also disconnect from the interconnect frame 201 through the embedded hole block 501 and the threaded plug 502. In this case, the drug will be continuously delivered, and the air exhaled by the patient will not affect the normal introduction of the drug in the interconnect frame 201. Therefore, the conical groove guide tube 601 and the lightweight plug bead 602 are mainly for the case of drug delivery through both the mouth and nose, to avoid backflow of exhaled air and thus avoid affecting the drug delivery pipeline.
[0043] The flow control frame 302 is disposed at the atomized medicine inlet end of the housing frame 301. The flow control frame 302 is equipped with a sliding section 303 that can slide. The sliding section 303 can control the atomized medicine inlet of the flow control frame 302.
[0044] Furthermore, the limiting card holder 701 is fixedly installed on one side of the receiving rack 301; the card mounting bracket 702 is inserted into one side of the receiving rack 301 and cooperates with the limiting card holder 701; the sliding block 703 is slidably installed on the side of the card mounting bracket 702 near the receiving rack 301; the sensing module 704 is installed on the side of the sliding block 703 near the receiving rack 301; the tightening bolt 705 is rotatably connected to the sliding block 703 and threadedly connected to the card mounting bracket 702.
[0045] Furthermore, the adapter plate 706 engages with the drive slot provided on the sliding section plate 303 and is slidably mounted on the mounting frame 702; the adjusting screw 707 is threadedly connected to the adapter plate 706 and rotatably mounted on the mounting frame 702; the output end of the self-controlled motor 708 is connected to the adjusting screw 707, and the self-controlled motor 708 is fixedly mounted on one side of the mounting frame 702; the electronic control module 709 is electrically connected to the self-controlled motor 708 and to the sensing module 704, and is mounted on one side of the mounting frame 702.
[0046] In this embodiment, the limiting card holder 701 and the side of the receiving rack 301 form an assembly groove structure that cooperates with the card mounting frame 702, so that the card mounting frame 702 can be quickly assembled by sliding down. The side of the receiving rack 301 is provided with a snap-in side opening for cooperating with the sliding block 703. The sensing module 704 is provided on the side of the sliding block 703. The sensing module 704 is mainly used to continuously detect the concentration of the atomized drug solution inside the receiving rack 301. The sensing module 704 integrates a corresponding concentration detection sensor. Currently, a micro electrochemical sensor can be used, which mainly utilizes the oxidation-reduction reaction of drug molecules on a specific electrode surface to generate current. By measuring the magnitude of this current, the concentration of the drug can be determined.
[0047] During actual installation, the mounting bracket 702 is first slid down for installation. Then, by tightening the tightening bolt 705, since the end of the tightening bolt 705 is rotatably connected to the mounting bracket 702, the tightening bolt 705 can engage with the threaded hole of the mounting bracket 702, thereby driving the sliding block 703 to continuously push the sensing module 704 into the receiving rack 301, so that the concentration of the medicine solution in the receiving rack 301 can be continuously detected through the sensing module 704.
[0048] The mounting bracket 702 is also provided with a corresponding adapter plate 706. The adapter plate 706 cooperates with the corresponding drive slot of the sliding section plate 303. When the mounting bracket 702 slides down for installation, the adapter plate 706 can engage with the sliding section plate 303. The adapter plate 706 is driven by the adjusting screw 707, which is driven by the self-controlled motor 708. The self-controlled motor 708 is controlled by the electronic control module 709, which integrates an independent power supply and a corresponding control system.
[0049] The control system integrated in the electronic control module 709 can control the self-controlled motor 708 based on the concentration sensing data from the sensing module 704. During normal administration of the nebulized medication, the concentration of the nebulized medication in the receiving frame 301 will change significantly in a short period of time due to the patient's inhalation of the nebulized medication. At this time, the sliding cut-off plate 303 will open the inlet of the flow control frame 302 under the action of the adapter plate 706. When the patient does not absorb the medication normally, the concentration of the nebulized medication in the receiving frame 301 will increase continuously, remain unchanged, or slowly decrease due to the continuous feeding of the nebulized medication and the inability to absorb it quickly and normally. At this time, the adapter plate 706 will drive the sliding cut-off plate 303 to block the inlet of the flow control frame 302 under the action of the control screw 707 and the self-controlled motor 708, so as to prevent the continuous dispersion of the nebulized medication.
[0050] Furthermore, the internally threaded cylinder 401 is fixedly installed on one side of the flow control frame 302; the threaded connector 402 is threadedly connected to the internally threaded cylinder 401; the inlet pipe 403 is fixedly installed on one side of the threaded connector 402 and connected to the output end of the external atomizer.
[0051] In this embodiment, the inlet of the flow control frame 302 is provided with the internally threaded cylinder 401, and the access tube 403 is used to cooperate with the internally threaded cylinder 401 through the threaded connector 402, and then the nebulized drug is continuously introduced through the access tube 403.
[0052] Preferably, the guide assembly provided by the present invention further includes a discharge frame 801, a one-way control frame 802, a discharge pipe 803, and an interception turner 804.
[0053] Furthermore, the discharge rack 801 is fixedly installed on one side of the mask body 101; the one-way control rack 802 is fixedly installed on one side of the discharge rack 801; the discharge pipe 803 is fixedly installed at the bottom of the one-way control rack 802; and the interception rotating rack 804 is rotatably installed inside the one-way control rack 802.
[0054] In this embodiment, the discharge frame 801 is fixedly installed on the mask body 101. A one-way control frame 802 is provided between the discharge frame 801 and the discharge pipe 803. An interception frame 804 is rotatably installed inside the one-way control frame 802. The interception frame 804 is adapted to the inclined guide groove provided by the one-way control frame 802. A corresponding counterweight is provided at the bottom of the interception frame 804. Both the interception frame 804 and the counterweight are made of lightweight materials. By setting the counterweight, the center of gravity of the interception frame 804 can be lowered so that the interception frame 804 can block the inclined opening that connects the one-way control frame 802 and the discharge frame 801 under normal conditions.
[0055] The discharge frame 801, together with the one-way control frame 802 and the discharge pipe 803, can realize the directional exhaust of the mask body 101. A corresponding purification structure can be set at the port of the exhaust pipe to avoid the patient's exhaled gas from polluting the external environment.
[0056] The intercepting rotating frame 804, installed within the one-way control frame 802, is primarily used for one-way gas exit. During normal exhalation, the intercepting rotating frame 804 rotates laterally due to the airflow, allowing gas from the exhaust frame 801 to be introduced into the one-way control frame 802 and then exited through the exhaust tube 803. When the patient inhales or does not exhale, the intercepting rotating frame 804, guided by its own weight and the corresponding reverse airflow, blocks the oblique opening connecting the one-way control frame 802 and the exhaust frame 801, thereby achieving one-way gas exit.
[0057] Please see Figure 11A respiratory drug delivery method based on nebulization technology, using the aforementioned nebulization-based respiratory drug delivery device, includes the following steps. S1: Select a nose cover 104 of appropriate size according to the patient's nose size, and install the nose cover 104 on the card slot plate 103 by using the card platform 105 set on the nose cover 104. When the card platform 105 is inserted and assembled, the card teeth 106 set on the card slot plate 103 limit the card platform 105 to ensure the stability of the nose cover 104 after installation. S2: The mask body 101 is placed over the patient's mouth by the straps set on the side buckle frame 102, while ensuring that the nose cover 104 can fit in accordance with the patient's nose. S3: The atomized medicine output by the atomizer is then guided by the external component, and then introduced into the communicating inner groove of the nose cover 104 or the mask body 101 through the control component and the interconnection component. S4: The patient can use the nose cover 104 and the mask body 101 to introduce the atomized medicine through the nasal cavity or mouth. During the introduction process, the control component will analyze and judge the introduction of medicine based on the concentration of the introduced medicine and related data. S5: Based on the analysis and judgment of the corresponding drug infusion situation, the control component will adjust the output atomized drug solution accordingly or directly cut off the continuous output of the atomized drug solution.
[0058] The above-disclosed embodiments are merely one or more preferred embodiments of this application and should not be construed as limiting the scope of this application. Those skilled in the art can understand that all or part of the processes for implementing the above embodiments and equivalent changes made in accordance with the claims of this application still fall within the scope of this application.
Claims
1. A respiratory drug delivery device based on nebulization technology, comprising a mask body and side fasteners, wherein two side fasteners are fixedly installed on both sides of the mask body, characterized in that, It also includes conductive components; The guiding assembly includes a slot plate, a nose cover, a locking platform, locking teeth, an interconnecting component, an adjusting component, and an external component. The slot plate is fixedly installed on the mask body. The locking platforms are fixed on both sides of the nose cover. The bottom of the nose cover has a communicating inner groove. The locking platforms match the locking grooves on the slot plate. The locking teeth are fixedly installed on the slot plate and match the tooth grooves on the locking platforms. The interconnecting component is connected to the mask body and is used to control the corresponding communication relationship between the mask body and the nose cover. The adjusting component is connected to the mask body and is used to adjust the input of the nebulizer. The external component is connected to the output end of an external nebulizer and is used to guide the liquid medicine discharged from the nebulizer.
2. The respiratory drug delivery device based on nebulization technology as described in claim 1, characterized in that, The interconnection component includes an interconnection frame, a connecting pipe, and a control component. The interconnection frame is fixedly installed on the mask body. The connecting pipe is connected to the interconnection frame and is fixedly installed on the side of the mask body near the nose cover. The nose cover has a corresponding insertion hole that cooperates with the connecting pipe. The control component is connected to the mask body and is used to regulate the communication relationship between the interconnection frame and the mask body.
3. The respiratory drug delivery device based on nebulization technology as described in claim 1, characterized in that, The control component includes a receiving frame, a flow control frame, a sliding cut-off plate, a unidirectional conduction component, and a self-adjusting component. The receiving frame is fixedly installed on the mask body, and the receiving frame is connected to the interconnection frame through the unidirectional conduction component. The flow control frame is fixedly installed on one side of the receiving frame. The sliding cut-off plate is slidably installed on the flow control frame. The self-adjusting component is connected to the receiving frame and is used to drive and adjust the sliding cut-off plate according to the output of the medicine in the receiving frame.
4. The respiratory drug delivery device based on nebulization technology as described in claim 3, characterized in that, The external component includes an internally threaded cylinder, a threaded connector, and an access tube. The internally threaded cylinder is fixedly installed on one side of the flow control frame. The threaded connector is threadedly connected to the internally threaded cylinder. The access tube is fixedly installed on one side of the threaded connector and connected to the output end of the external atomizer.
5. The respiratory drug delivery device based on nebulization technology as described in claim 2, characterized in that, The control component includes an embedded hole block and a threaded plug. One side of the embedded hole block is connected to the interconnect frame, and the other side of the embedded hole block is connected to the mask body. The threaded plug is threadedly connected to the embedded hole block and passes through the embedded hole block.
6. The respiratory drug delivery device based on nebulization technology as described in claim 3, characterized in that, The unidirectional guiding component includes a conical groove guide cylinder and a lightweight plug bead. One side of the conical groove guide cylinder is connected to the interconnection frame, and the other side of the conical groove guide cylinder is connected to the receiving frame. The lightweight plug bead is disposed inside the conical groove guide cylinder.
7. The respiratory drug delivery device based on nebulization technology as described in claim 3, characterized in that, The self-adjusting component includes a limiting card holder, a mounting bracket, a sliding block, a sensing module, and a tightening bolt. The limiting card holder is fixedly installed on one side of the receiving rack. The mounting bracket is inserted into one side of the receiving rack and cooperates with the limiting card holder. The sliding block is slidably installed on the side of the mounting bracket near the receiving rack. The sensing module is installed on the side of the sliding block near the receiving rack. The tightening bolt is rotatably connected to the sliding block and threadedly connected to the mounting bracket.
8. The respiratory drug delivery device based on nebulization technology as described in claim 7, characterized in that, The self-adjusting component further includes an adapter plate, an adjusting screw, a self-controlled motor, and an electronic control module. The adapter plate engages with the drive slot provided on the sliding section plate and is slidably mounted on the mounting frame. The adjusting screw is threadedly connected to the adapter plate and rotatably mounted on the mounting frame. The output end of the self-controlled motor is connected to the adjusting screw, and the self-controlled motor is fixedly mounted on one side of the mounting frame. The electronic control module is electrically connected to the self-controlled motor and to the sensing module, and is mounted on one side of the mounting frame.
9. The respiratory drug delivery device based on nebulization technology as described in claim 1, characterized in that, The guiding assembly also includes a discharge frame, a one-way control frame, a discharge pipe, and an intercepting rotating frame. The discharge frame is fixedly installed on one side of the mask body; the one-way control frame is fixedly installed on one side of the discharge frame; the discharge pipe is fixedly installed at the bottom of the one-way control frame; and the intercepting rotating frame is rotatably installed inside the one-way control frame.
10. A respiratory drug delivery method based on nebulization technology, using the respiratory drug delivery device based on nebulization technology as described in claim 4, characterized in that, Includes the following steps, Select a nose cover of appropriate size according to the patient's nose size, and install the nose cover on the card slot plate by using the card platform set on the nose cover. When the card platform is inserted and assembled, the card teeth set on the card slot plate limit the card platform to ensure the stability of the nose cover after installation. The mask body is placed over the patient's mouth using straps on the side buckle frame, while ensuring that the nose cover fits the patient's nose accordingly. The atomized medicine output by the atomizer is then guided by an external component, and then introduced into the communicating inner groove of the nose cover or the mask body through the control component and the interconnection component. Patients can use the nose cover and the mask body to introduce atomized medication through the nasal cavity or mouth. During the introduction process, the control component will analyze and judge the introduction of medication based on the concentration of the introduced medication and related data. Based on the analysis and judgment of the corresponding drug infusion situation, the control component will adjust the output atomized drug solution accordingly or directly cut off the continuous output of the atomized drug solution.