Multi-channel independent switching liquid dosing device without cross contamination

Abstract

The application is suitable for the technical field of chemical reaction equipment, and provides a multi-channel independent switching liquid dosing device without cross contamination, which comprises a tank body, an obturator plate is arranged at the upper end of the tank body, a through hole is formed in the obturator plate, the through hole is located above the port of one dosing channel, the obturator plate is used for plugging other dosing channels, a plurality of vertical rods are fixedly connected to the obturator plate, a mixing mechanism is arranged in the tank body, the mixing mechanism is used for shielding the inner cavity of the tank body in a normal state, an adjusting mechanism is arranged at the bottom of the obturator plate, the adjusting mechanism is used for switching the working state of the mixing mechanism, and the mixing mechanism is used for mixing the liquid in the tank body and reducing the temperature of the liquid at the same time. The scheme provides an innovative heat dissipation path. When the movable piece rotates with the main shaft, the movable piece plays a role of a fan, forcibly stirs the air above the liquid surface, and accelerates heat dissipation. This can stably control the temperature of the mixed liquid in a low temperature range, and significantly improves the mixing safety and product quality of heat-sensitive chemicals such as certain biological preparations and volatile solvents.

Description

Technical Field

[0001] This invention belongs to the technical field of chemical reaction equipment, and particularly relates to a multi-channel, independently switchable liquid dosing device without cross-contamination. Background Technology

[0002] In the cutting-edge synthesis fields of fine chemicals, biomedicine, and specialty new materials, precise control of the reaction process directly determines the purity and yield of the final product. Current industrial production generally relies on various reaction vessels and supporting liquid dosing devices, with typical structures including tanks, mechanical stirring systems, thermostatic jackets, and top or side feed inlets.

[0003] However, as synthesis processes become increasingly complex, especially when dealing with heat-sensitive, highly active, or highly volatile chemicals (such as monoclonal antibody drug intermediates, nanomaterial precursors, low-temperature organolithium reagents, etc.), traditional dosing devices have revealed significant structural defects.

[0004] Specifically, traditional equipment often employs a fixed top cover design, resulting in a relatively sealed "dead zone" at the top of the tank. During vigorous exothermic reactions or prolonged stirring, the heat released by the reaction not only heats the liquid phase but also causes a rapid increase in the temperature of the upper gas phase space through conduction and convection. Due to the low thermal conductivity of gases, heat is difficult to dissipate, leading to a significant axial temperature gradient inside the tank.

[0005] The high-temperature gas phase directly acts on the gas-liquid interface, causing "localized superheating" of the liquid near the liquid surface. This non-uniform temperature field easily triggers accelerated vaporization of volatile organic solvents (such as tetrahydrofuran and dichloromethane) on the liquid surface. Excessive solvent evaporation not only changes the solute concentration in the liquid phase and disrupts the stoichiometric ratio, but also leads to solute supersaturation at the liquid surface.

[0006] In oxygen-containing environments or under specific catalytic conditions, the active ingredients on the liquid surface are highly susceptible to oxidative polymerization or rapid crystallization, forming a dense "surface crust." This crust not only hinders heat transfer but also detaches with stirring, forming irregular large impurities that severely affect product quality. Furthermore, existing single-channel or multi-channel dosing devices often leave pipeline residues when switching between different reagents, making true independent switching difficult and increasing the risk of cross-contamination.

[0007] To solve the above problems, it is necessary to design a multi-channel, independently switchable liquid dosing device that prevents cross-contamination. Summary of the Invention

[0008] This invention provides a multi-channel, independently switchable, cross-contamination-free liquid dosing device to solve the problem that poor heat dissipation in traditional chemical dosing devices leads to heat accumulation inside the tank, causing local overheating and surface crusting, which affects the quality of heat-sensitive agents.

[0009] The present invention is implemented as follows: a multi-channel independently switchable liquid dosing device without cross-contamination includes a tank body, a bearing seat installed inside the tank body, an annular ring rotatably installed inside the tank body via the bearing seat, a plurality of dosing channels arranged in a circumferential array fixedly installed inside the annular ring, and an annular seat sleeved and fixedly installed on the upper end of the tank body, the annular seat having a plurality of limiting holes arranged in a circumferential array.

[0010] The upper end of the tank is provided with a sealing plate, and the sealing plate has a through-hole located above the port of one of the dosing channels. The sealing plate is used to block the ports of other dosing channels. Multiple vertical rods are fixedly connected to the sealing plate, and the vertical rods are respectively inserted into the limiting holes. The tank is provided with a mixing mechanism, which is normally used to shield the inner cavity of the tank. The bottom of the sealing plate is provided with an adjustment mechanism, which is used to switch the working state of the mixing mechanism, so that the mixing mechanism can reduce the liquid temperature while mixing the liquid inside the tank.

[0011] Preferably, multiple support columns are fixedly installed on the outside of the tank, and the lower end of the tank is funnel-shaped.

[0012] Preferably, a drain pipe is connected to and fixedly installed at the bottom of the tank, and a valve is installed on the drain pipe.

[0013] Preferably, a gear ring is fitted and fixedly connected to the annular ring, a stepper motor is fixedly mounted on the annular seat, and a drive wheel is fixedly mounted on the output shaft end of the stepper motor, the drive wheel meshing with the gear ring.

[0014] Preferably, the mixing mechanism includes a vertical shaft rotatably mounted inside the tank, on which multiple blades arranged in a circumferential array are fixedly mounted, and a servo motor is fixedly mounted outside the tank, with the output shaft of the servo motor fixedly connected to the vertical shaft.

[0015] Preferably, the mixing mechanism further includes multiple baffles fixedly connected to the inside of the tank, the multiple baffles being arranged in a circumferential array, a groove being fixedly installed at the upper end of the vertical shaft, and multiple horizontal shafts arranged in a circumferential array being rotatably installed on the groove, with movable plates fixedly installed at the outer ends of each horizontal shaft, the movable plates being located above the baffles, the multiple horizontal movable plates cooperating with the multiple baffles to seal the upper port of the tank, friction wheels being fixedly installed at the inner ends of each horizontal shaft, and a first magnet being fixedly connected to each friction wheel, with a second magnet provided on the opposite side of each first magnet, the second magnet being fixedly connected to the groove, and when the movable plates are in a horizontal state, the first magnet and the second magnet are opposite to each other and there is an attraction between them.

[0016] Preferably, the adjustment mechanism includes an extension rod rotatably mounted on the bottom of the sealing plate, the bottom of the extension rod being fixedly mounted with a spline, the spline being inserted into the groove and connected to the spline of the groove.

[0017] Preferably, a plurality of drive bars arranged in a circumferential array are fixedly installed at the bottom of the extension rod. The surface of the drive bars is provided with anti-slip texture. The drive bars are in contact with the friction wheel and the two are transmitted through friction.

[0018] Preferably, the tank body has multiple copper pipes extending into the inner cavity of the tank body, and the copper pipes are provided with cooling medium channels for the flow of cooling medium.

[0019] Preferably, an elastic sealing gasket is fixedly attached to the bottom of the sealing plate, and the position of the elastic sealing gasket corresponds one-to-one with the upper port of the multiple dosing channels.

[0020] Compared with related technologies, the multi-channel independently switching, cross-contamination-free liquid dosing device provided by the present invention has the following advantages: 1. Addressing the common problems of "localized overheating" and "surface crusting" in chemical mixing, this solution offers an innovative heat dissipation path. As the movable plate rotates with the spindle, it acts as a fan, forcibly agitating the air above the liquid surface and accelerating heat dissipation. This stabilizes the temperature of the mixture within a low-temperature range, significantly improving the mixing safety and product quality of heat-sensitive chemicals such as certain biological agents and volatile solvents.

[0021] 2. By designing movable plates that play different roles under different operating conditions, the plates function as a sealing cap when not in use, using magnetism to keep the tank opening horizontal and prevent debris from falling in and chemicals from splashing out. During operation, they transform into a stirring component and a cooling fan. This reusable design simplifies the mechanical structure and reduces equipment costs.

[0022] 3. By using the installation action of the sealing plate as a trigger signal, the extension rod and friction wheel work together to automatically switch from "static sealing" to "open stirring". No additional electric or pneumatic devices are needed to control the opening and closing of the tank opening, realizing the mechanical automation logic of "open when filling, seal when unpacking", which is simple to operate and responds quickly.

[0023] 4. This device uses a ring array of independent dosing channels with a zoned blocking design and precise channel switching driven by a stepper motor. Only one dosing channel is opened at a time for the corresponding agent to be added. The upper ports of the remaining closed channels are isolated by blocking plates to avoid contact paths between different agents and to prevent cross-contamination during the dosing process from the root.

[0024] 5. The sealing plate can be quickly installed and removed through the limiting holes of the vertical rod and the annular seat. When the device is stopped, the upper port of the tank can be exposed by removing the sealing plate and other structural components, which makes it easier for the staff to clean the inside of the tank. Attached Figure Description

[0025] Figure 1 This is a schematic diagram of the structure of the present invention; Figure 2 This is a partial structural schematic diagram of the present invention; Figure 3 This is an exploded view of the present invention; Figure 4 This is an exploded view of the extension rod, spline, and drive bar in this invention; Figure 5 This is an exploded view of the bearing housing, annular ring, and dosing channel in this invention; Figure 6 This is a cross-sectional view of the tank body in this invention; Figure 7 This is an enlarged schematic diagram of a portion of the structure of the blades and movable plates in this invention; Figure 8 This is an enlarged cross-sectional view of a portion of the structure of the tank in this invention; Figure 9 For the present invention Figure 8 Enlarged structural diagram at point A in the middle.

[0026] In the diagram: 1. Tank body; 2. Bearing seat; 3. Annular ring; 4. Dosing channel; 5. Annular seat; 6. Limiting hole; 7. Sealing plate; 8. Through-hole; 9. Vertical rod; 10. Support column; 11. Drain pipe; 12. Valve; 13. Gear ring; 14. Stepper motor; 15. Drive wheel; 16. Vertical shaft; 17. Blade; 18. Servo motor; 19. Baffle; 20. Tank body; 21. Horizontal shaft; 22. Movable plate; 23. Friction wheel; 24. First magnet; 25. Second magnet; 26. Extension rod; 27. Spline; 28. Drive bar. Detailed Implementation

[0027] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this application belongs; the terminology used herein in the specification of the application is for the purpose of describing particular embodiments only and is not intended to be limiting of the application; the terms "comprising" and "having," and any variations thereof, in the specification, claims, and foregoing drawings of this application are intended to cover non-exclusive inclusion. The terms "first," "second," etc., in the specification, claims, or foregoing drawings of this application are used to distinguish different objects, not to describe a particular order.

[0028] In this document, the term "embodiment" means that a particular feature, structure, or characteristic described in connection with an embodiment may be included in at least one embodiment of this application. The appearance of this phrase in various places throughout the specification does not necessarily refer to the same embodiment, nor is it a separate or alternative embodiment mutually exclusive with other embodiments. It will be explicitly and implicitly understood by those skilled in the art that the embodiments described herein can be combined with other embodiments.

[0029] A preferred embodiment of the multi-channel independently switching, cross-contamination-free liquid dosing device provided by the present invention is, for example... Figures 1 to 9 As shown: A multi-channel, independently switchable, cross-contamination-free liquid dosing device includes a tank 1, a bearing seat 2 installed inside the tank 1, an annular ring 3 rotatably installed inside the tank 1 via the bearing seat 2, a plurality of dosing channels 4 arranged in a circular array fixedly installed inside the annular ring 3, and an annular seat 5 fitted and fixedly installed on the upper end of the tank 1, with a plurality of limiting holes 6 arranged in a circular array on the annular seat 5.

[0030] The upper end of the tank body 1 is provided with a sealing plate 7, and the sealing plate 7 has a through hole 8. The through hole 8 is located above the port of one of the dosing channels 4. The sealing plate 7 is used to block the ports of other dosing channels 4. Multiple vertical rods 9 are fixedly connected to the sealing plate 7. The vertical rods 9 are inserted into the limiting holes 6 respectively. The tank body 1 is provided with a mixing mechanism. Under normal conditions, the mixing mechanism is used to cover the inner cavity of the tank body 1. The bottom of the sealing plate 7 is provided with an adjustment mechanism. The adjustment mechanism is used to switch the working state of the mixing mechanism, so that the mixing mechanism can reduce the liquid temperature while mixing the liquid inside the tank body 1.

[0031] Multiple support columns 10 are fixedly installed on the outside of the tank body 1, and the lower end of the tank body 1 is funnel-shaped. A drain pipe 11 is connected to and fixedly installed at the bottom of the tank body 1, and a valve 12 is installed on the drain pipe 11.

[0032] A gear ring 13 is fitted and fixedly connected to the outer ring 3. A stepper motor 14 is fixedly installed on the ring seat 5. A drive wheel 15 is fixedly installed on the output shaft end of the stepper motor 14. The drive wheel 15 meshes with the gear ring 13.

[0033] External materials are added into the device through the inlet 8. Cross-contamination is prevented by independent channel switching and partition sealing. When the dosing channel 4 is switched independently, the stepper motor 14 drives the drive wheel 15 to rotate. Through the meshing transmission with the gear ring 13, the ring ring 3 is rotated as a whole. Different dosing channels 4 can be rotated sequentially to the inlet 8 of the sealing plate 7 to achieve independent switching of multiple channels. Only one dosing channel 4 is opened at a time for the addition of the corresponding agent.

[0034] The upper ports of the remaining unopened dosing channels 4 will be completely sealed by the sealing plate 7 to prevent different agents from coming into contact or mixing during the dosing process, thus avoiding cross-contamination at the source.

[0035] Under normal conditions, the mixing mechanism will shield and seal the upper part of the inner cavity of tank 1 to prevent the agent from splashing out during the dosing process, and at the same time prevent external impurities from entering the tank and contaminating the agent. When it is necessary to treat the agent in the tank, the adjusting mechanism can switch the working state of the mixing mechanism. During the dosing and mixing process, the mixing mechanism will start to stir and mix the liquid inside tank 1. At the same time, the adjusting mechanism will switch the working state of the mixing mechanism. The mixing mechanism will cool the liquid simultaneously during mixing to meet the process requirements for liquid temperature.

[0036] This device uses a ring array of independent dosing channels 4 with a partitioned blocking design and precise channel switching driven by a stepper motor 14. Only one dosing channel 4 is opened at a time for the corresponding agent to be added. The upper ports of the remaining closed channels are isolated by the blocking plate 7 to avoid contact paths between different agents and to prevent cross-contamination during the dosing process from the root.

[0037] Meanwhile, the sealing plate 7 can be quickly disassembled and assembled through the vertical rod 9 and the limiting hole 6 of the annular seat 5. When the device is stopped, the upper port of the tank 1 can be exposed by removing the sealing plate 7 and other structural components, which makes it easier for staff to clean the inside of the tank 1.

[0038] In a further preferred embodiment of the present invention: The mixing mechanism includes a vertical shaft 16 rotatably installed inside the tank 1, with multiple blades 17 arranged in a circular array fixedly installed on the vertical shaft 16, and a servo motor 18 fixedly installed outside the tank 1, with the output shaft of the servo motor 18 fixedly connected to the vertical shaft 16.

[0039] The mixing mechanism also includes multiple baffles 19 fixedly connected to the inner side of the tank 1. The baffles 19 are arranged in a circumferential array. A trough 20 is fixedly installed at the upper end of the vertical shaft 16. Multiple horizontal shafts 21 arranged in a circumferential array are rotatably installed on the trough 20. Movable plates 22 are fixedly installed at the outer ends of the horizontal shafts 21. The movable plates 22 are located above the baffles 19. The multiple horizontal movable plates 22 cooperate with the multiple baffles 19 to block the upper port of the tank 1. Friction wheels 23 are fixedly installed at the inner ends of the horizontal shafts 21. A first magnet 24 is fixedly connected to each friction wheel 23. A second magnet 25 is provided on the opposite side of the first magnet 24. The second magnet 25 is fixedly connected to the trough 20. When the movable plates 22 are in a horizontal state, the first magnet 24 and the second magnet 25 are opposite each other and there is an attraction between them, so that the horizontal state of the movable plates 22 remains stable.

[0040] The adjustment mechanism includes an extension rod 26 that is rotatably mounted on the bottom of the sealing plate 7. A spline 27 is fixedly mounted on the bottom of the extension rod 26. The spline 27 is inserted into the groove 20 and connected to the spline of the groove 20.

[0041] Multiple drive bars 28 arranged in a circular array are fixedly installed at the bottom of the extension rod 26. The surface of the drive bars 28 is provided with anti-slip texture. The drive bars 28 contact the friction wheel 23 respectively and the two are transmitted through friction.

[0042] Multiple copper pipes extend through the tank body 1 into its inner cavity. Cooling medium channels are provided inside the copper pipes. These channels are used to circulate the cooling medium and, in conjunction with the mixing mechanism, improve the cooling efficiency of the liquid inside the tank.

[0043] An elastic sealing gasket is fixedly attached to the bottom of the sealing plate 7, and the position of the elastic sealing gasket corresponds one-to-one with the upper port of the multiple dosing channels 4. When the sealing plate 7 blocks the port of the dosing channel 4, the elastic sealing gasket is squeezed and deformed to achieve port sealing and prevent the agent from evaporating or leaking.

[0044] In this embodiment, based on Embodiment 1, the mixing mechanism, adjusting mechanism, and sealing structure are refined, representing a more specific optimization scheme. The working principle is as follows: In the non-working state, structural components such as the annular seat 5 are removed from the device, exposing the upper port of the tank 1. The movable piece 22 remains in a horizontal state. At this time, the attraction between the first magnet 24 and the second magnet 25 maintains the horizontal posture of the movable piece 22. The multiple horizontal movable pieces 22, together with the baffle 19 inside the tank 1, jointly seal the upper port of the tank 1, which can not only prevent the medicine from splashing out during the dosing process, but also prevent external impurities from entering the tank.

[0045] When mixing is performed, the sealing plate 7 is installed on the device, and the vertical rods 9 are inserted into the limiting holes 6 respectively. During the installation process of the sealing plate 7 into the device, the extension rod 26 and multiple drive bars 28 below the sealing plate 7 are inserted into the tank 20. The drive bars 28 drive the friction wheel 23 to rotate through friction, which in turn drives the horizontal shaft 21 to rotate, causing the movable plate 22 to rotate 90 degrees and release the seal on the upper port of the tank 1. At the same time, the spline 27 at the bottom of the extension rod 26 is inserted into the tank 20 and splined. When the vertical shaft 16 and the tank 20 rotate, the tank 20 can be driven to rotate synchronously. The servo motor 18 drives the vertical shaft 16 to rotate, which drives the blades 17 to stir the liquid in the tank 1, so as to achieve uniform mixing of the agent.

[0046] During the mixing process, the vertical shaft 16 drives the tank 20 and multiple movable plates 22 on its outer side to rotate synchronously. The rotation of these movable plates 22 accelerates the airflow above the liquid surface, simulating a fan action to quickly remove heat generated during mixing and stabilize the temperature of the mixture within a low-temperature range. The movable plates 22 not only serve as a sealing structure but also as an auxiliary heat dissipation structure. During mixing, they forcibly agitate the air above the liquid surface, solving the common problems of "surface crusting" or "localized overheating" in chemical mixing, and stabilizing the temperature of the mixture within a low-temperature range. This is particularly suitable for the addition of heat-sensitive chemicals.

[0047] With the continuous flow of cooling medium in the copper pipes, the liquid flow can be stirred by the blades 17 to improve the heat exchange efficiency between the liquid and the cooling medium in the tank, further accelerating the cooling speed of the liquid in the tank 1, realizing the simultaneous mixing and cooling, and improving the overall processing efficiency.

[0048] To address the common problems of "localized overheating" and "surface crusting" in chemical mixing, this solution offers an innovative heat dissipation path. As the movable plate 22 rotates with the spindle, it acts as a fan, forcibly agitating the air above the liquid surface and accelerating heat dissipation. This effectively keeps the mixture temperature stably controlled within a low-temperature range, significantly improving the mixing safety and product quality of heat-sensitive chemicals such as certain biological agents and volatile solvents.

[0049] By designing the movable piece 22 to perform different functions under different operating conditions, it acts as a sealing cap structure in the non-operating state, using magnetic force to keep the tank opening horizontal and prevent debris from falling in and chemicals from splashing out; in the operating state, it transforms into a stirring component and a cooling fan. This reusable design simplifies the mechanical structure and reduces equipment costs.

[0050] By using the installation action of the sealing plate 7 as a trigger signal, the extension rod 26 and the friction wheel 23 work together to automatically switch from "static sealing" to "open stirring". No additional electric or pneumatic devices are needed to control the opening and closing of the tank opening, realizing the mechanical automation logic of "open when filling, seal when unpacking", which is simple to operate and responds quickly.

[0051] The above embodiments are only used to illustrate the technical solutions of the present invention, and are not intended to limit the scope of protection of the invention. Obviously, the described embodiments are only some embodiments of the present invention, not all embodiments. Based on these embodiments, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention. Although the present invention has been described in detail with reference to the above embodiments, those skilled in the art can still combine, add, delete, or otherwise adjust the features of the various embodiments of the present invention according to the circumstances without conflict or creative effort, thereby obtaining different technical solutions that do not fundamentally depart from the concept of the present invention. These technical solutions also fall within the scope of protection of the present invention.

Claims

1. A multi-channel, independently switchable, cross-contamination-free liquid dosing device, characterized in that, Includes a tank body (1), a bearing seat (2) is installed inside the tank body (1), an annular ring (3) is rotatably installed inside the tank body (1) via the bearing seat (2), a plurality of dosing channels (4) arranged in a circular array are fixedly installed inside the annular ring (3), and an annular seat (5) is sleeved and fixedly installed on the upper end of the tank body (1), and a plurality of limiting holes (6) arranged in a circular array are opened on the annular seat (5); The upper end of the tank (1) is provided with a sealing plate (7), and the sealing plate (7) is provided with a through hole (8). The through hole (8) is located above the port of one of the dosing channels (4). The sealing plate (7) is used to block the ports of other dosing channels (4). Multiple vertical rods (9) are fixedly connected to the sealing plate (7). The vertical rods (9) are respectively inserted into the limiting holes (6). The tank (1) is provided with a mixing mechanism. The mixing mechanism is normally used to cover the inner cavity of the tank (1). The bottom of the sealing plate (7) is provided with an adjustment mechanism. The adjustment mechanism is used to switch the working state of the mixing mechanism so that the mixing mechanism reduces the liquid temperature while mixing the liquid inside the tank (1).

2. The multi-channel independently switching, cross-contamination-free liquid dosing device as described in claim 1, characterized in that, Multiple support columns (10) are fixedly installed on the outside of the tank (1), and the lower end of the tank (1) is funnel-shaped.

3. The multi-channel independently switching, cross-contamination-free liquid dosing device as described in claim 2, characterized in that, The bottom of the tank (1) is connected to and fixedly installed with a drain pipe (11), and a valve (12) is installed on the drain pipe (11).

4. The multi-channel independently switching, cross-contamination-free liquid dosing device as described in claim 1, characterized in that, A gear ring (13) is fitted over and fixedly connected to the annular ring (3). A stepper motor (14) is fixedly installed on the annular seat (5). A drive wheel (15) is fixedly installed at the output shaft end of the stepper motor (14). The drive wheel (15) meshes with the gear ring (13).

5. The multi-channel independently switching, cross-contamination-free liquid dosing device as described in claim 1, characterized in that, The mixing mechanism includes a vertical shaft (16) rotatably installed inside the tank (1), on which multiple blades (17) arranged in a circular array are fixedly installed, and a servo motor (18) is fixedly installed outside the tank (1), with the output shaft of the servo motor (18) fixedly connected to the vertical shaft (16).

6. The multi-channel independently switching, cross-contamination-free liquid dosing device as described in claim 5, characterized in that, The mixing mechanism also includes multiple baffles (19) fixedly connected to the inner side of the tank (1). The multiple baffles (19) are arranged in a circular array. A groove (20) is fixedly installed at the upper end of the vertical shaft (16). Multiple horizontal shafts (21) arranged in a circular array are rotatably installed on the groove (20). Movable plates (22) are fixedly installed at the outer ends of each horizontal shaft (21). The movable plates (22) are located above the baffles (19). The multiple horizontal movable plates (22) cooperate with each other. Multiple baffles (19) block the upper port of the tank (1). Friction wheels (23) are fixedly installed on the inner end of the horizontal shaft (21). A first magnet (24) is fixedly connected to each friction wheel (23). A second magnet (25) is provided on the opposite side of the first magnet (24). The second magnet (25) is fixedly connected to the tank (20). When the movable piece (22) is in a horizontal state, the first magnet (24) and the second magnet (25) are opposite each other and there is an attraction between them.

7. The multi-channel independently switching, cross-contamination-free liquid dosing device as described in claim 6, characterized in that, The adjustment mechanism includes an extension rod (26) rotatably mounted on the bottom of the sealing plate (7), and a spline (27) is fixedly mounted on the bottom of the extension rod (26). The spline (27) is inserted into the groove (20) and connected to the spline of the groove (20).

8. The multi-channel independently switching, cross-contamination-free liquid dosing device as described in claim 7, characterized in that, The bottom of the extension rod (26) is fixedly equipped with a plurality of drive bars (28) arranged in a circular array. The surface of the drive bars (28) is provided with anti-slip texture. The drive bars (28) are in contact with the friction wheel (23) respectively and the two are transmitted through friction.

9. The multi-channel independently switching, cross-contamination-free liquid dosing device as described in claim 1, characterized in that, The tank (1) has multiple copper pipes extending into the inner cavity of the tank (1), and the copper pipes are provided with cooling medium channels for circulating cooling medium.

10. The multi-channel independently switching, cross-contamination-free liquid dosing device as described in claim 1, characterized in that, An elastic sealing gasket is fixedly pasted to the bottom of the sealing plate (7), and the position of the elastic sealing gasket corresponds one-to-one with the upper port of the multiple drug dosing channels (4).

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