Polymer-containing composition with improved uv-blocking enhancing effect, and cosmetic composition comprising the same

Abstract

The present invention relates to a composition for enhancing the effect of ultraviolet blocking and a method for preparing the same, the composition containing a polymer and a cosmetic composition. More particularly, by using a polymer as an additive in a cosmetic composition, the feeling of stickiness upon use can be improved, skin permeation can be prevented, and a high SPF (sun protection factor) can be achieved even with a low content of an ultraviolet blocking agent, and in vivo SPF can be enhanced.

Description

Technical Field

[0001] This disclosure relates to compositions having a synergistic effect of enhanced UV blocking, comprising polymers. More specifically, the present invention relates to a composition having an enhanced UV blocking effect that improves stickiness during application, prevents skin penetration, achieves a high sun protection factor (SPF) even with low UV blocking agent content, and increases the SPF in vivo by using polymers as additives in cosmetic compositions, as well as cosmetic compositions containing the above composition. Background Technology

[0002] Ultraviolet (UV) blockers can be broadly categorized into inorganic and organic UV blockers. Each type of UV blocker has mixing limits set by the Food and Drug Administration (FDA). Due to these mixing limits, inorganic UV blockers can cause a white cloud on the skin and are difficult to apply due to their thick formulation. Furthermore, it is known that absorption of inorganic UV blockers through the skin can increase the risk of cancer or dementia. Organic UV blockers are also absorbed through the skin, and if absorbed at levels exceeding safety standards, they may increase the risk of side effects such as cancer or birth defects.

[0003] Thus, when UV-blocking agents are absorbed into the dermis of the skin, they can cause skin cancer as a side effect. To address this issue, if the UV-blocking agent is encapsulated in a material that enhances SPF, less UV-blocking agent can be used, and absorption into the skin can be inhibited. Furthermore, existing sunscreens, which use organic UV-blocking agents, contain 30% organic UV-blocking agents by weight, accounting for 30% of the total weight of the sunscreen. Therefore, due to the sticky nature derived from the characteristics of organic UV-blocking agents, they can cause discomfort during application.

[0004] Furthermore, recently, there has been a problem of false SPF manipulation in sunscreen products on the market. These products share a common characteristic: they use organic UV-blocking agents, and among the widely used organic UV-blocking agents are UV-A blockers such as phenyl benzoyl diethylaminobenzoate (Uvinul A+), UV-B blockers such as ethylhexyl triazine (Uvinul T 150), and UV-A blockers such as diethylhexyloxyphenol methoxyphenyl triazine (Tinosorb S). By using these ingredients, it is claimed that they contain two or three UV-blocking agents.

[0005] It is generally known that it is difficult to achieve an SPF 50+ or ​​PA++++ effect using only two or three ingredients in the manufacture of sunscreen, and it is problematic to cause irritation regardless of the EWG rating if each ingredient is added at its maximum concentration. Furthermore, since SPF values ​​are affected by UV-B blocking, the value increases when a large amount of UV-B blocker is added. Therefore, it is common practice to add 5 to 7% by weight of organic UV blocker ingredients and a large amount of inorganic UV blocker related to coverage to increase the SPF value. Additionally, while SPF can be increased by using UV-A blockers, this requires a large amount, so most products use UV-B, and most products combine two or three organic UV blocker ingredients with an inorganic UV blocker added simultaneously.

[0006] Therefore, there is a need to develop a UV blocker that has the effects of SPF 50+ and PA++++ without using inorganic UV blockers and minimizes the content of organic UV blockers by reducing their content to less than 5% by weight, as well as an additive that can be used with existing UV blockers.

[0007] [Existing Technical Documents]

[0008] [Patent Literature]

[0009] Korean Patent Publication No. 10-2011-0137157A (December 22, 2011) Summary of the Invention

[0010] Based on research findings on the aforementioned shortcomings of the prior art, the inventors of this invention discovered that although its UV blocking agent content is lower than that of existing products, it has a synergistic effect that maximizes the UV blocking efficacy, improves the stickiness during use, inhibits the absorption of organic UV blocking agent components into the skin, and reduces environmental pollution because it decomposes naturally upon disposal.

[0011] Therefore, the purpose of this disclosure is to provide an ultraviolet blocking efficacy enhancer composition having these functions.

[0012] According to one embodiment of this disclosure, a UV blocking efficacy enhancer composition is provided, the composition comprising a polymer, wherein the polymer contained in the composition has a D 50 (Volume) is 0.1-10μm.

[0013] Furthermore, according to one embodiment of this disclosure, the polymer is characterized in that it is a biodegradable polymer.

[0014] Furthermore, according to one embodiment of this disclosure, the polymer is characterized by having at least one NH group and a carbonyl functional group.

[0015] Furthermore, according to one embodiment of this disclosure, the polymer is characterized in that it is selected from at least one of polyhydroxyalkanoate (PHA), polymethyl methacrylate (PMMA), poly-L-lactic acid (PLLA), and polyethyleneimine (PEI).

[0016] According to one embodiment of this disclosure, this disclosure provides a cosmetic composition comprising a polymer; and an oil; wherein the polymer contained in the composition has a D 50 (Volume) is 0.1-10μm.

[0017] Furthermore, according to one embodiment of this disclosure, a cosmetic composition is provided, characterized in that the polymer encapsulates an ultraviolet blocking agent component.

[0018] Furthermore, according to one embodiment of this disclosure, the polymer is characterized in that the content of the composition relative to the total weight of the cosmetic composition is greater than 0 and less than or equal to 10% by weight.

[0019] Furthermore, according to one embodiment of this disclosure, the cosmetic composition also contains other organic UV blocking agents besides the polymer, and said organic UV blocking agent is characterized in that it is selected from one or more of the following: ethylhexyl methoxycinnamate (OMC), bis(ethylhexyloxyphenol) methoxyphenyl triazine (TS), polysiloxane-15, isoamyl p-methoxycinnamate, phenyl diethylaminohydroxybenzoyl hexanoate, ethylhexyl triazine ketone, butyl methoxydibenzoylmethane, ethylhexyl salicylate, cinnamon ethylhexanoate, salicylolactone, ethylhexyl triazine ketone, and octocrylene.

[0020] Furthermore, according to one embodiment of this disclosure, the cosmetic composition is characterized in that it is used for UV blocking.

[0021] Furthermore, according to one embodiment of this disclosure, the composition is characterized in that it comprises a formulation selected from: solutions, ointments, topical ointments, lotions, fragrances, foaming agents, acne creams, nourishing acne creams, moisturizing lotions, softening acne creams, dressings, fluids, cosmetic bases, soaps, detergents, bath preparations, sunscreens, sun oils, suspensions, emulsifiers, pastes, gels, lotions, powders, detergents containing surfactants, oils, base makeup, foundations, lotion base makeup, wax base makeup, patches, and sprays.

[0022] The UV blocking efficacy enhancer compositions and cosmetic compositions containing these compositions of the present invention have a synergistic effect, maximizing UV blocking efficacy even when containing fewer UV-blocking ingredients than existing products, and improving the user experience by containing fewer UV-blocking ingredients with a sticky feel. Furthermore, they have an enhancing effect by maximizing UV blocking efficacy by inhibiting the absorption of organic UV blocking agents into the skin, and they also have the advantage of reducing environmental pollution when discarded. Attached Figure Description

[0023] Figure 1 The graph shows the results of in vitro analysis of UV spectral data, indicating that when a dispersion (including PHA) according to one embodiment of the present disclosure is added, the UV-A and B regions broaden overall, and thus the SPF / PA increases. Detailed Implementation

[0024] The present invention will now be described in more detail.

[0025] The terms and words used in this specification should not be construed as being limited to ordinary or dictionary terms, and should be interpreted in accordance with the meaning and concept consistent with the technical spirit of this disclosure, based on the principle that the inventor is able to define the concepts of terms that best describe his invention.

[0026] The terminology used herein is for describing particular embodiments only and is not intended to limit the invention. Unless the context clearly indicates otherwise, the singular forms “1(a)”, “an”, and “the” include plural references. It should be understood that the terms “comprise” or “have” as used in this disclosure mean the presence of a feature, number, step, operation, component, part, or combination thereof described in the specification, but do not preclude the possibility of the presence or addition of one or more other features, numbers, steps, operations, components, parts, or combinations thereof.

[0027] First, this disclosure provides an ultraviolet blocking efficacy enhancer composition comprising a polymer, wherein the polymer contained in the composition has a D 50 (Volume) is 0.1-10μm.

[0028] The inventors have discovered that if polymers are used to inhibit the absorption of UV blocking agents into the skin, they not only have a synergistic effect that maximizes UV blocking efficacy, but also minimize environmental pollution because they decompose naturally upon disposal.

[0029] The UV blocking efficacy enhancement composition of the present invention comprises a polymer, wherein the polymer may be, but is not limited to, a biodegradable polymer.

[0030] The polymer contained in the UV blocking efficacy enhancer composition of the present invention may be at least one selected from the following substances: polyhydroxyalkanoate (PHA), polymethyl methacrylate (PMMA), poly-L-lactic acid (PLLA), and polyethyleneimine (PEI). When these polymers are used with UV blocking agent ingredients, if the absorption of UV blocking agent ingredients by the skin is inhibited, not only is there a synergistic effect that maximizes UV blocking efficacy, but also environmental pollution is minimized because they decompose naturally upon disposal.

[0031] Furthermore, the polymer contained in the UV blocking efficacy enhancement composition of the present invention may have at least one NH group and a carbonyl functional group. When a polymer having such functional groups is used with a UV blocking agent component, this can inhibit the absorption of the UV blocking agent component into the skin.

[0032] Furthermore, the polymer contained in the UV blocking efficacy enhancer composition according to this disclosure can have a D0.1-10 μm. 50 (Volume). Here, D 50 (Volume) refers to the particle size at which the cumulative particle size distribution in a polymer powder reaches 50% (by volume). When the polymer's D 50 When the volume is within the above range, it acts as an enhancer when used with UV blocking agents, maximizing the UV blocking effect and inhibiting the absorption of UV blocking agents into the skin.

[0033] Specifically, the D of the polymer contained in the composition 50 The (volume) can be greater than 0.1μm, greater than 0.3μm, greater than 0.5μm, greater than 1.0μm, greater than 2.0μm, and can be less than 10μm, less than 8μm, less than 6μm, less than 5μm, less than 4μm, less than 3μm, or less than 1.5μm.

[0034] Next, this disclosure provides a cosmetic composition comprising the aforementioned UV blocking efficacy enhancer composition.

[0035] The cosmetic compositions disclosed herein comprise a polymer; an oil; characterized in that the polymer has a D 50 (Volume) is 0.1-10μm.

[0036] The polymer contained in the cosmetic composition disclosed herein may encapsulate ultraviolet blocking agent components, but is not limited thereto.

[0037] The polymer contained in the cosmetic composition disclosed herein may contain an amount greater than 0 and less than or equal to 10% by weight relative to the total weight of the cosmetic composition, and preferably may contain an amount of 0.001% or more by weight, 0.01% or more by weight, 0.1% or more by weight, 1.0% or more by weight, or 2.0% or more by weight, and may contain an amount of less than 8% by weight, less than 6% by weight, less than 5% by weight, less than 4% by weight, or less than 3% by weight.

[0038] When the polymer content is higher than the above range, a feeling of pressure is felt on the skin.

[0039] The cosmetic compositions disclosed herein may also contain other organic ultraviolet (UV) blocking agents besides polymers. The organic UV blocking agents contained in the cosmetic compositions of the present invention may account for 3-10% by weight of the total weight of the cosmetic composition. The cosmetic compositions of the present invention have an enhancing effect; even with a small content of organic UV blocking agents, the UV blocking efficiency can be maximized by containing the aforementioned polymers.

[0040] When the content of organic UV blocker is less than 3% by weight, there is a problem of insufficient UV blocking effect, and when the content of organic UV blocker is more than 10% by weight, there is a problem of poor user experience (stickiness).

[0041] Specifically, relative to the total weight of the cosmetic composition, the content of the organic ultraviolet blocker can be 3.0% by weight or more, 3.5% by weight or more, 4.0% by weight or more, 4.5% by weight or more, and can be less than 10.0% by weight, less than 8.0% by weight, less than 6.0% by weight or less than 4.5% by weight.

[0042] Specifically, the organic ultraviolet blocking agent may be selected from at least one of the following: ethylhexyl methoxycinnamate (OMC), diethylhexyloxyphenol methoxyphenyl triazine (TS), polysiloxane-15, p-methoxycinnamate isoamyl ester, diethylaminohydroxybenzoyl benzoate hexyl ethylhexyl triazine ketone, butyl methoxydibenzoylmethane, ethylhexyl salicylate, ethylhexyl cinnamate, hydroxybenzoate, ethylhexyl triazine ketone, and diacetone glycerol.

[0043] The cosmetic compositions disclosed herein include UV blocking efficacy enhancer compositions, wherein if diethylhexyloxyphenol methoxyphenyl triazine (TS) is used as an organic UV blocker, it has a synergistic effect of more than 5 times or more than 10 times on UV blocking compared to the case where it is not used.

[0044] Furthermore, the cosmetic composition of the present invention includes a UV blocking efficacy enhancer composition, and in this case, if ethylhexyl methoxycinnamate (OMC) is used as an organic UV blocker, it has a synergistic effect of 1.5 times, 2 times, 5 times, or 10 times or more on UV blocking compared to not using it.

[0045] The specific embodiments of the polymer are the same as those of the polymer contained in the above-described UV blocking efficacy enhancement composition.

[0046] In addition, this polymer can be used as an additive in existing UV blockers.

[0047] Existing UV blockers can be any commercially available UV blocker.

[0048] The cosmetic composition disclosed herein can be used as an additive to all commercially available ultraviolet (UV) blockers. When used as an additive, an increase in UV spectrum peak width and SPF / PA value can be confirmed by Experimental Example 4 below. Furthermore, even when less than 1% of the present invention is used as an additive, the effects of the present invention, i.e., the enhancing effect, are produced.

[0049] The cosmetic composition disclosed herein may contain an inorganic ultraviolet blocking agent, wherein the content of the inorganic ultraviolet blocking agent is 1-10% by weight relative to the total amount of the cosmetic composition.

[0050] When the content of inorganic ultraviolet blocking agent is less than 1% by weight, there is a problem of insufficient physical UV blocking effect. When the content of inorganic ultraviolet blocking agent is higher than 10% by weight, there is a problem of white cloudiness on the skin.

[0051] Specifically, relative to the total weight of the cosmetic composition, the inorganic ultraviolet blocking agent may be present in an amount of 1.0% or more by weight, 2.0% or more by weight, 3.0% or more by weight, or 4.0% or more by weight, and may be present in an amount of less than 10.0% by weight, less than 8.0% by weight, less than 6.0% by weight, or less than 4.0% by weight.

[0052] Specifically, the inorganic ultraviolet blocking agent may be at least one selected from zinc oxide, titanium dioxide, and cerium oxide.

[0053] The oil contained in the cosmetic composition disclosed herein can be used in cosmetic compositions, such as MCT oil, without particular limitation.

[0054] The cosmetic composition of the present invention comprises a formulation selected from the group consisting of solutions, ointments, topical creams, creams, serums, foaming agents, lotions, nourishing lotions, softening lotions, moisturizing lotions, dressings, fluids, primers, soaps, cleansers, bath preparations, sunscreens, sun oils, suspensions, emulsions, pastes, gels, lotions, powders, surfactant-containing cleansers, oils, foundations, powder foundations, liquid foundations, wax foundations, patches, and sprays.

[0055] The method for preparing the cosmetic composition of the present invention can be used without particular limitation, as long as it is a device capable of applying shear stress, and specifically one or more devices selected from homogenizers, high-pressure homogenizers, silica-filled homogenizers, rotor-stator homogenizers, piston homogenizers and tubular homogenizers can be used.

[0056] Specifically, the polymer disclosed herein can be introduced into the device together with an emulsifier and then mixed.

[0057] As emulsifiers, polyoxyethylene sorbitan (Tween), polyoxyethylene-polyoxypropylene copolymer (poloxamer), sorbitol ester (Span), polyoxyethylene ether (Brij), and glyceryl stearate citrate can be used, and emulsifiers such as Tween are preferred.

[0058] In addition, mixing can be carried out at a speed of 5,000 to 10,000 RPM for 3 to 10 minutes.

[0059] Then, the mixture is mixed 1 to 5 times using a high-pressure homogenizer (HPH) at a pressure of 1000-2000 bar.

[0060] After adding distilled water again, mix for 5 to 15 minutes at a speed of 2000 to 5000 RPM, and then repeat the process using a high-pressure homogenizer in the same manner as above.

[0061] Subsequently, a speed-varying concentrator can be used to remove solvents such as chloroform to prepare the final dispersion, which is a UV blocking efficacy enhancer composition.

[0062] If necessary, an organic UV blocker such as TS or OMC can be added in advance during the preparation of the synergist composition.

[0063] Subsequently, various ingredients used in the cosmetic composition (such as MCT oil, phytosemide, lactic acid, 1,2-hexanediol, etc.) and various organic or inorganic UV blocking agents discussed above can be mixed with the dispersion to prepare the cosmetic composition.

[0064] The invention will now be described in more detail with reference to preferred embodiments. However, the scope of protection of this disclosure is not limited to these embodiments.

[0065] Example

[0066] 1. Chemical substances used

[0067] 1) Preparation of dispersion

[0068] Chloroform; Glyceryl stearate citrate (GSC); UV filter materials, such as bis(ethylhexyloxyphenol) methoxyphenyl triazine (TS, TINOSORB S); ethylhexyl methoxycinnamate (OMC); polyhydroxyalkanoates (PHA); 1,2-hexanediol (product name: Activonol-6).

[0069] 2) Preparation of cosmetic compositions

[0070] Caprylic / capric triglyceride (MCT oil), phytane sphingosine, lactic acid, titanium dioxide (e.g., TiO2 dispersion (aqueous, 30%), a product commercially available from Agrabatti), 1,2-hexanediol (Activonol-6).

[0071] The device used

[0072] 1) Preparation of dispersion

[0073] The equipment included a mixer, a high-pressure homogenizer (PandaPLUS 2000, from GEA Niro Soavi), a rotary evaporator, a dryer (oven), and a particle size analyzer (MasterSizer3000, from Malvern).

[0074] 2) Preparation of cosmetic compositions

[0075] Homogenizer, high-pressure homogenizer (PandaPLUS 2000, from GEA Niro Soavi).

[0076] 3) Sun Protection Factor (SPF) Analysis

[0077] In vitro SPF measurement (SPF-290AS_Solar Light company, owned by Korea Ceramic Technology Research Institute)

[0078] In vivo SPF measurement (External analysis institutions: Korean Skin Research Association, Gyeonggi Province, South Korea; Skinmed, Daejeon, South Korea)

[0079] 1. Preparation of dispersion

[0080] Example 1: Preparation of a polyhydroxyalkanoate (PHA) dispersion

[0081] Add 2.8g of glyceryl stearate citrate (GSC, EVONIK's Dermofeel) to a beaker. TM Add 14g of GSCSG powder and 14g of polyhydroxyalkanoate (PHA, a raw material from CJ-bio). Then add chloroform to bring the total weight to 400g and run the homogenizer at 7,000 RPM for 5 minutes.

[0082] The solution thus prepared is treated with a high-pressure homogenizer (HPH) and the process is repeated three times at a pressure of 1300 bar to prepare the final solution.

[0083] Then add 700g of distilled water to the beaker and run the homogenizer at 3000RPM. Slowly add 300g of the previously prepared solution and disperse the mixture by running it at 5000RPM for 10 minutes. Then perform five treatments using HPH at a pressure of 1300 bar.

[0084] Subsequently, chloroform was completely removed using a rotary evaporator at 60°C, and some distilled water was further removed using a rate-varying condenser to prepare the final dispersion.

[0085] The dry solids content of the prepared dispersion (calculated by weight measurement after drying at 80°C for more than 12 hours) was determined to be 21% by weight, and the particle size distribution was determined to be D using a Malvern Master Sizer 3000 instrument. 50 (Volume) 0.6μm.

[0086] Example 2. Preparation of a dispersion of PHA containing an organic UV blocker.

[0087] Add 2.92g of glyceryl stearate citrate (GSC, EVONIK's Dermofeel) to a beaker. TM GSCSG powder and 14.60g of polyhydroxyalkanoate (PHA) powder.

[0088] Then chloroform was added to bring the total weight to 400g, and 5.26g of bis(ethylhexyloxyphenol) methoxyphenyl triazine (TS, TINOSORB S) powder and 12.26g of ethylhexyl methoxycinnamate (OMC) solution were added. The mixture was then run in a homogenizer at 7000 RPM for 5 minutes.

[0089] The solution prepared in this way is subjected to HPH, and this process is repeated three times at a pressure of 1300 bar to prepare the final solution.

[0090] Then add 700g of distilled water to the beaker and run the homogenizer at 3000 RPM, and slowly add 300g of the previously prepared solution. Then disperse the mixture by running it at 5000 RPM for 10 minutes, and then perform 5 treatments at 1300 bar using HPH.

[0091] Then, chloroform was completely removed using a rotary evaporator at 60°C, and some distilled water was further removed to prepare the final dispersion.

[0092] Analysis confirmed that the dry solids content of the prepared dispersion was 51% by weight, and the particle size distribution was D. 50 (Volume) 0.7μm.

[0093] Example 3: Preparation of a dispersion of polymethyl methacrylate (PMMA).

[0094] The dispersion was prepared using the same method as in Dispersion Preparation Example 1, except that 14 g of polymethyl methacrylate (PMMA, molecular weight 350k, product from Aldrich) was used instead of polyhydroxyalkanoate in Dispersion Preparation Example 1.

[0095] Analysis confirmed that the dry solids content of the prepared dispersion was 18% by weight, and the particle size distribution was D. 50 (Volume) 0.6μm.

[0096] Example 4: Preparation of a dispersion of poly-L-lactic acid (PLLA).

[0097] The dispersion was prepared using the same method as in Dispersion Preparation Example 1, except that 14 g of poly-L-lactic acid (PLLA, molecular weight 100k, product from Aldrich) was used instead of polyhydroxyalkanoate in Dispersion Preparation Example 1.

[0098] Analysis confirmed that the dry solids content of the prepared dispersion was 18% by weight, and the particle size distribution was D. 50 (Volume) 1.2μm.

[0099] Example 5: Preparation of a polystyrene dispersion.

[0100] The dispersion was prepared using the same method as in Dispersion Preparation Example 1, except that 14 g of polystyrene (PS, molecular weight 350k, product from Aldrich) was used instead of polyhydroxyalkanoate in Dispersion Preparation Example 1.

[0101] Analysis confirmed that the dry solids content of the prepared dispersion was 18% by weight, and the particle size distribution was D. 50 (Volume) 0.6μm.

[0102] Unlike the polymers of the present invention, polystyrene has a structure that does not contain NH groups and carbonyl groups, and is therefore used to compare the effects of the present invention.

[0103] Example 6. Preparation of a dispersion of PHA containing an organic UV blocker.

[0104] The dispersion was prepared under the same conditions as in Dispersion Preparation Example 2, except that in Dispersion Preparation Example 2, ethylhexyl methoxycinnamate (OMC) was not used, and 17.52 g of ethylhexyloxyphenol methoxyphenyl triazine (TS, TINOSORB S) powder was used instead of OMC.

[0105] Analysis confirmed that the dry solids content of the prepared dispersion was 38% by weight, and the particle size distribution was D. 50 (Volume) 0.7μm.

[0106] 2. Preparation of cosmetic compositions

[0107] Example 1

[0108] A cosmetic composition was prepared by mixing 28.6 wt% of the dispersion prepared in Dispersion Preparation Example 1, 3.3 wt% of titanium dioxide (TiO2, TiO2 dispersion (water-soluble, 30%), a product from Agarbatti), 44.0 wt% of caprylic / capric triglyceride (MCT Oil), 2.0 wt% of phytosphingosine (PhSG, a product from Phytosphingosine Solus Biotech), 4.5 wt% of 1 mol lactic acid, 2.0 wt% of 1,2-hexanediol (Activonol-6), 1.8 wt% of bis(ethylhexyloxyphenol) methoxyphenyl triazine (TS, TINOSORB S), 4.2 wt% of ethylhexyl methoxycinnamate (OMC), and the balance of distilled water.

[0109] Example 2: Preparation of cosmetic composition

[0110] A cosmetic composition was prepared by mixing 23.5 wt% of the dispersion prepared in Dispersion Preparation Example 2, 3.3 wt% of titanium dioxide (TiO2, TiO2 dispersion (soluble in water, 30%), from Agarbatti (manufactured by SINA BTCo. Ltd)), 44.0 wt% of caprylic / capric triglyceride (MCT oil), 2.0 wt% of phytane sphingosine, 4.5 wt% of 1 mol lactic acid, 2.0 wt% of 1,2-hexanediol (Activonol-6), and the balance of distilled water.

[0111] Example 3: Preparation of cosmetic composition

[0112] The cosmetic composition was prepared using the same method as in Example 2, except that 35.3% by weight of the dispersion was used to prepare the dispersion prepared in Example 2, and 5.0% by weight of titanium dioxide was used.

[0113] Example 4: Preparation of cosmetic composition

[0114] The cosmetic composition was prepared using the same method as in Example 1, except that 0.9 wt% of bis(ethylhexyloxyphenol)methoxyphenyltriazine (TS, TINOSORB S) and 2.1 wt% of ethylhexyl methoxycinnamate (OMC) were used.

[0115] Example 5: Preparation of cosmetic composition

[0116] The cosmetic composition was prepared using the same method as in Example 4, except that a 33.3% by weight dispersion prepared in Example 3 was used.

[0117] Example 6. Preparation of cosmetic composition

[0118] The cosmetic composition was prepared using the same method as in Example 4, except that a 33.3% by weight dispersion prepared in Example 4 was used.

[0119] Example 7. Preparation of cosmetic composition

[0120] The cosmetic composition was prepared using the same method as in Example 4, except that a 33.3% by weight dispersion prepared in Example 5 was used.

[0121] Example 8. Preparation of cosmetic composition

[0122] The cosmetic composition was prepared in the same manner as in Example 1, except that the 28.6% by weight dispersion prepared in Example 1 was prepared using a dispersion, and 3.0% by weight of bis(ethylhexyloxyphenol) methoxyphenyltriazine (TS, TINOSORB S) was used instead of bis(ethylhexyloxyphenol) methoxyphenyltriazine (TS, TINOSORB S) and ethylhexyl methoxycinnamate (OMC).

[0123] Example 9. Preparation of cosmetic composition

[0124] The cosmetic composition was prepared using the same method as in Example 8, except that 3.0% by weight of ethylhexyl methoxycinnamate (OMC) was used instead of diethylhexyloxyphenol methoxyphenyl triazine (TS, TINOSORB S).

[0125] Example 10. Preparation of cosmetic composition

[0126] The cosmetic was prepared using the same method as in Example 8, except that 3.0 wt% of methylenebis-benzotriazolyltetramethylbutylphenol (TM) was used instead of bisethylhexyloxyphenol methoxyphenyltriazine (TS, TINOSORBS).

[0127] Example 11. Preparation of cosmetic composition

[0128] The cosmetic was prepared using the same method as in Example 8, except that 3.0% by weight of isoamyl p-methoxycinnamate (IMC) was used instead of bis(ethylhexyloxyphenol)methoxyphenyltriazine (TS, TINOSORB S).

[0129] Example 12. Preparation of cosmetic composition

[0130] The cosmetic was prepared using the same method as in Example 8, except that 3.0% by weight of humosaside (Parsol HMS) was used instead of bis(ethylhexyloxyphenol) methoxyphenyl triazine (TS, TINOSORB S).

[0131] Example 13 Preparation of cosmetic composition

[0132] A cosmetic composition was prepared by replacing water with a dispersion prepared in Example 1, which was prepared by adding 2.0% by weight of a dispersion to a commercially available product, Celenin the young UV Moisture Milk.

[0133] Example 14. Preparation of cosmetic composition

[0134] A cosmetic composition was prepared by adding 11.4% by weight of dispersion to commercially available Celenin the youngUV Moisture Milk in place of water and bis(ethylhexyloxyphenol)methoxyphenyltriazine (TS, TINOSORB S).

[0135] Comparative Example 1: Preparation of a cosmetic composition

[0136] The cosmetic was prepared using the same method as in Example 1, except that the dispersion prepared in Dispersion Preparation Example 1 was not used.

[0137] Comparative Example 2. Preparation of a cosmetic composition

[0138] The cosmetic was prepared using the same method as Comparative Example 1, except that 0.9 wt% of bis(ethylhexyloxyphenol)methoxyphenyltriazine (TS, TINOSORB S) and 2.1 wt% of ethylhexyl methoxycinnamate (OMC) were used.

[0139] Comparative Example 3. Preparation of Cosmetic Compositions

[0140] The cosmetic was prepared using the same method as in Example 8, except that a dispersion was not used in Example 8.

[0141] Comparative Example 4. Preparation of Cosmetic Compositions

[0142] The cosmetic was prepared using the same method as in Example 9, except that a dispersion was not used in Example 9.

[0143] Comparative Example 5: Preparation of Cosmetic Compositions

[0144] The cosmetic was prepared using the same method as in Example 10, except that a dispersion was not used in Example 10.

[0145] Comparative Example 6. Preparation of Cosmetic Compositions

[0146] The cosmetic was prepared using the same method as in Example 11, except that a dispersion was not used in Example 11.

[0147] Comparative Example 7. Preparation of a cosmetic composition

[0148] The cosmetic was prepared using the same method as in Example 12, except that a dispersion was not used in Example 12.

[0149] Comparative Example 8: Preparation of a cosmetic composition

[0150] Use the product Celenin the young UV Moisture Milk.

[0151] Experimental Example

[0152] Experimental Example 1. Measurement of SPF and SPF / PA in vitro and in vivo (Comparative Example 1, Examples 1 to 3)

[0153] In vitro SPF measurement methods

[0154] The cosmetic formulation was applied to each of five polymethyl methacrylate (PMMA) plates at a concentration of 1.3 mg / cm². 2 Nine points were measured on each board; measurements were performed using equipment owned by the Korea Ceramic Technology Research Institute, specifically an SPF-290AS manufactured by Solar Light Corporation.

[0155] In vivo SPF / PA measurement methods

[0156] The test was conducted by an external testing organization (Korea Institute of Dermatological Sciences, Seoul, Korea / Skinmed Clinical Trial Center Co., Ltd., Daejeon, Korea) according to the standard method for measuring sun protection factor (ISO 24444:2019 / ISO 24442:2011), and the results are shown in Table 1.

[0157] Table 1:

[0158] As shown in Table 1, the results confirmed that SPF was significantly increased in vitro in Examples 1 to 3 compared to Comparative Example 1, which did not contain PHA.

[0159] When comparing Comparative Example 1 with Example 1, it was confirmed that the SPF increased slightly while the PA increased significantly. Furthermore, when comparing Comparative Example 1 with Example 2, it was confirmed that both SPF and PA increased significantly in Example 3 when UV-blocking ingredients such as TS or OMC were encapsulated into the PHA. This can be attributed to the fact that efficiency is improved when organic UV-blocking ingredients are encapsulated into the PHA and are not absorbed by the skin.

[0160] Furthermore, as shown in Example 3, SPF 50+ / PA++++ can be achieved even with small amounts of inorganic and organic UV blockers, thus confirming that the effect of enhancing the in vivo sun protection factor is significant when the dispersion presented in this disclosure is included.

[0161] Experimental Example 2. Determination of SPF and SPF / PA in vitro and in vivo (Comparative Example 2, Examples 4 to 7)

[0162] In vitro SPF measurement methods

[0163] The cosmetic formulation was applied to each of five polymethyl methacrylate (PMMA) plates at a concentration of 1.3 mg / cm². 2 Nine points were measured on each board; the measurements were performed using equipment owned by the Korea Ceramic Technology Research Institute, specifically the Solar Light SPF-290AS.

[0164] Table 2

[0165] As shown in Table 2, the in vitro SPF was significantly increased in Example 4 compared to Comparative Example 2, which did not contain PHA. Furthermore, the SPF was also significantly increased in Examples 4 and 5, which contained PMMA and PLLA instead of PHA, compared to Comparative Example 2.

[0166] However, in Example 7, where PS without NH- or carbonyl functional groups was used instead of PHA, no increase in in vitro SPF was observed compared to Comparative Example 2. This suggests that the resin additive used should contain functional groups to significantly improve the in vivo sun protection factor. The molecular structures of the resin additives used in this experiment are shown in Table 3 below.

[0167] Table 3:

[0168] Experimental Example 3. Comparison of the sun protection factor enhancement effect of PHA dispersions

[0169] In vitro SPF measurement methods

[0170] The cosmetic formulation was applied to each of five polymethyl methacrylate (PMMA) plates at a concentration of 1.3 mg / cm². 2 Nine points were measured on each board; measurements were performed using equipment owned by the Korea Ceramic Technology Research Institute, specifically a Solar Light SPF-290AS.

[0171] Table 4:

[0172] Table 5:

[0173] As shown in Tables 4 and 5, when comparing the changes in SPF with and without the addition of PHA dispersion (sample, example), it can be seen that the effect of enhancing the in vivo sun protection factor depends on the type of organic UV blocker, and Example 8, which contains TS organic UV blocker, shows the most significant effect.

[0174] Furthermore, although the sun protection factor values ​​were improved in Example 10 containing TM organic UV blocker and Example 12 containing Parsol HMS organic UV blocker, the effect could not be considered significant because the SPF values ​​were low.

[0175] Therefore, when studying the sun protection factor enhancement effect of PHA dispersion, it was found that the order of effect was TS>>OMC>IMC>TM=Parsol HMS.

[0176] Experimental Example 4: Comparison of SPF values ​​measured using the compositions disclosed herein as additives in existing commercial UV blockers.

[0177] In vitro SPF measurement method

[0178] The cosmetic formulation was applied to each of five polymethyl methacrylate (PMMA) plates at a concentration of 1.3 mg / cm². 2 Nine points were measured on each board; measurements were performed using equipment owned by the Korea Ceramic Technology Research Institute, specifically the Solar Light SPF-290AS.

[0179] Table 6:

[0180] As shown in Table 6, the results confirm that the dispersion of this disclosure significantly increases both in vitro SPF and in vivo SPF / PA when added to commercially available CELENINTHE YOUNG UV moisturizing emulsion containing various organic UV blockers.

[0181] Furthermore, when the product was changed to a powder containing TS (an organic UV-blocking ingredient contained in the commercial product CELENIN THE YOUNG UV Moisturizing Lotion) encapsulated within PHA, the UV blocking efficiency was further improved as the SPF value increased significantly to 55, as described in Experimental Example 1.

[0182] Furthermore, since SPF / PA is increased by adding only a small amount of the dispersion presented in this invention (dispersion preparation example 1) to commercial products, it is expected that it can be widely used as a UV blocking synergist when used as an additive in other sunscreen product groups.

Claims

1. A composition for enhancing ultraviolet blocking efficacy, comprising a polymer, wherein the polymer contained in the composition has a D 50 (Volume) ranges from 0.1 to 10 μm.

2. The UV blocking efficacy enhancer composition as described in claim 1, wherein, The polymer is a biodegradable polymer.

3. The UV blocking efficacy enhancer composition as described in claim 1, wherein, The polymer has at least one functional group selected from NH group and carbonyl group.

4. The UV blocking efficacy enhancer composition as described in claim 1, wherein, The polymer is at least one selected from the group consisting of: polyhydroxyalkanoate (PHA), polymethyl methacrylate (PMMA), poly-L-lactic acid (PLLA), and polyethyleneimine (PEI).

5. A cosmetic composition comprising a polymer; and an oil, wherein, The polymer's D 50 (Volume) ranges from 0.1 to 10 μm.

6. The cosmetic composition of claim 5, wherein, The polymer encapsulates the ultraviolet blocking agent component.

7. The cosmetic composition of claim 5, wherein, The content of the polymer relative to the total weight of the cosmetic composition is greater than 0 and less than or equal to 10% by weight.

8. The cosmetic composition of claim 5, wherein, The polymer is a biodegradable polymer.

9. The cosmetic composition of claim 5, wherein, The polymer has at least one functional group selected from NH group and carbonyl group.

10. The cosmetic composition of claim 5, wherein, The polymer is at least one selected from the group consisting of: polyhydroxyalkanoate (PHA), polymethyl methacrylate (PMMA), poly-L-lactic acid (PLLA), and polyethyleneimine (PEI).

11. The cosmetic composition of claim 5, wherein, The cosmetic composition further comprises other organic UV blockers besides the polymer, and the organic UV blockers are at least one selected from the group consisting of: ethylhexyl methoxycinnamate (OMC), bis(ethylhexyloxyphenol) methoxyphenyl triazine (TS), polysiloxane-15, isoamyl p-methoxycinnamate, hexyl diethylaminohydroxybenzoylbenzoate, ethylhexyl triazine ketone, butyl methoxydibenzoylmethane, ethylhexyl salicylate, ethylhexyl cinnamate, humosalilate, ethylhexyl triazine ketone, and octocrylene.

12. The cosmetic composition of claim 5, wherein, The cosmetic composition is used for ultraviolet (UV) blocking.

13. The cosmetic composition of claim 5, wherein, The composition comprises a formulation selected from the group consisting of solutions, ointments, topical creams, lotions, serums, foams, lotions, nourishing lotions, softening lotions, moisturizing lotions, dressings, fluids, primers, soaps, cleansers, bath preparations, sunscreens, sun oils, suspensions, emulsions, pastes, gels, lotions, powders, surfactant-containing cleansers, oils, foundations, powder foundations, liquid foundations, wax foundations, patches, and sprays.

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