A bio-based low-foam high-efficiency composite disinfecting and cleaning powder and a preparation method thereof

Abstract

This invention discloses a bio-based, low-foaming, high-efficiency composite disinfectant cleaning powder and its preparation method, belonging to the technical field of disinfectant cleaning product preparation. The composite disinfectant cleaning powder comprises the following raw materials in parts by weight: 15-19 parts by weight of surfactant-coating enzyme, 1-2 parts by weight of fabric softener, 1-5 parts by weight of plant-derived antibacterial ingredient, and 2-3 parts by weight of alkaline additive. This invention obtains a composite disinfectant cleaning powder with good detergency and bactericidal effects by dry mixing the surfactant-coating enzyme, fabric softener, plant-derived antibacterial ingredient, and alkaline additive, with low foam production and no skin irritation.

Description

Technical Field

[0001] This invention belongs to the field of disinfection and cleaning product preparation technology, specifically relating to a bio-based low-foaming, high-efficiency composite disinfection and cleaning powder and its preparation method. Background Technology

[0002] The cleaning industry covers almost all sectors, including home appliances and furniture, clothing, industrial instruments, high-speed trains and automobiles, petrochemicals, mining and metallurgy, semiconductors and electronics, biomedicine, and lasers. Therefore, cleaning agents have enormous market potential. For routine cleaning and fabric washing, current cleaning agents mainly include liquid water-based cleaners and solid cleaning powders. Water-based cleaners work by utilizing water, a solvent with good solubility, and then using surfactants to alter surface tension, emulsifying and penetrating organic dirt to reduce its adhesion to surfaces, thus achieving a washing effect. While water-based cleaners are widely used, their cleaning effectiveness is generally limited. This is mainly because the cleaning effect of water-based cleaners is highly dependent on water quality. Tap water is mostly hard water, containing a high amount of calcium and magnesium ions, which combine with the anionic surfactants in water-based cleaners to form precipitates, thus weakening the cleaning ability. Using soft water requires pretreatment with filtration equipment, which is costly. Solid powder cleaning products are the mainstream form of cleaning agents used in hotel and hotel laundry rooms. The products have many advantages when made into powder: (1) The production process is simple and the products can be easily prepared by dry mixing; (2) Powdered products have better water quality adaptability and can be washed well under hard water conditions; (3) There is no need to consider the solubility between components, and more raw materials that are beneficial to washing can be added; (4) For ingredients with activity requirements (such as biological enzymes), powdered cleaning agents have better stability in storage because they avoid contact with liquids. Due to the nature of stains on fabrics in environments such as hotels and restaurants, using only one type of detergent for each wash is often insufficient. A combination of several detergents is typically required to complete the washing process. This typically includes five products: strong laundry detergent (containing high levels of strong alkalis such as sodium hydroxide, which can harm the skin upon contact), emulsion, bleaching powder (which bleaches and disinfects but is also harmful to the skin and environment), neutralizing powder (containing fluorescent whitening and brightening agents, which are also harmful to the environment), and starching powder. If necessary, alkaline additives and water softeners may also be added. Furthermore, the timing of adding different products, the operating temperature, and the washing time all vary, making the process not only time-consuming and labor-intensive but also posing certain risks to cleaning personnel. Therefore, while solid powder detergents are less demanding in terms of water quality compared to liquid detergents, being usable in both soft and hard water, their composition and usage significantly complicate their practical application.

[0003] Therefore, developing a solid powder cleaning product that has good stain removal, sterilization, environmental friendliness, and does not harm human skin has important application value. Summary of the Invention

[0004] To address the shortcomings of existing technologies, this invention provides a composite disinfectant cleaning powder with excellent detergency and antibacterial effects by dry-mixing surfactant-coating enzymes, fabric softeners, plant-derived antibacterial ingredients, and alkaline additives. This powder is non-irritating to the skin, thus solving the technical problems mentioned in the background art. Specifically, the technical solution of this invention includes the following:

[0005] One objective of this invention is to provide a bio-based, low-foaming, high-efficiency composite disinfectant and cleaning powder, wherein the composite disinfectant and cleaning powder comprises the following raw materials in parts by weight:

[0006] 15-19 parts by weight of surfactant coating enzyme, 1-2 parts by weight of fabric softener, 1-5 parts by weight of plant-derived antibacterial ingredient, and 2-3 parts by weight of alkaline additive.

[0007] Furthermore, the method for preparing the surfactant-coated enzyme includes the following steps:

[0008] Surfactant, deionized water and sodium periodate were mixed in a weight ratio of 1:20~30:1~1.5 and protected from light. The mixture was then reacted at 25℃~30℃ for 40min~60min to obtain an oxidized surfactant.

[0009] An oxidizing surfactant, a linker, and anhydrous ethanol are mixed in a weight ratio of 7-8:1-2:100-150 and reacted at 25℃-30℃ for 24-30 hours to obtain a Gemini surfactant.

[0010] Gemini surfactant, crosslinking agent, polyhydroxybenzene ring compound and anhydrous acetone are mixed in a weight ratio of 1:0.1~0.2:0.5~0.9:20~25 and the pH is adjusted to 9~9.5. Then the mixture is reacted at 25℃~30℃ for 1h~2h to obtain modified Gemini surfactant.

[0011] Modified Gemini surfactant, biological enzyme, and deionized water were mixed and stirred in a weight ratio of 2~3:1~1.5:25~30 to obtain a coated enzyme dispersion;

[0012] The surfactant-coated enzyme was obtained by spray drying the coated enzyme dispersion.

[0013] Furthermore, the surfactant includes tea saponin, which is a nonionic surfactant and needs to have a multi-hydroxyl vicinal diol structure for subsequent construction of a high-temperature resistant protection system. Compared with anionic and cationic surfactants, it can avoid precipitation reactions with metal salt ions in water and avoid affecting the activity of biological enzymes.

[0014] Furthermore, the linker includes ethylenediamine, and the carbon chain of the linker cannot be too long, otherwise the long hydrophobic carbon chain may increase the hydrophobicity of the surfactant and cause it to lose its cleaning effect.

[0015] Furthermore, the crosslinking agent includes divinyl sulfone.

[0016] Furthermore, the polyhydroxybenzene ring compound includes quercetin.

[0017] Furthermore, the bio-enzyme is composed of alkaline protease, lipase and cellulase in a weight ratio of 1:1:1.

[0018] Furthermore, the mixing conditions include a temperature of 5℃~6℃, a stirring speed of 100r / min, and a stirring time of 20h~24h.

[0019] Furthermore, the spray drying conditions include an inlet air temperature of 110℃~120℃, a feed rate of 8mL / min~9mL / min, and an outlet air temperature of 55℃~60℃.

[0020] Furthermore, the fabric softener includes fabric softener RL-118 or fabric softener RL-128, the plant-derived antibacterial ingredient includes honeysuckle extract or rosemary extract, and the alkaline adjuvant is composed of sodium carbonate and sodium metasilicate in a weight ratio of 1:1. This plant-derived antibacterial ingredient is readily available commercially. If other plant-derived antibacterial ingredients that are not easily obtained are added, they can be prepared by extraction methods such as water extraction or alcohol extraction.

[0021] A second objective of this invention is to provide a method for preparing a bio-based low-foaming, high-efficiency composite disinfectant cleaning powder, the preparation method comprising the following steps:

[0022] The composite disinfectant and cleaning powder is obtained by dry mixing 15-19 parts by weight of surfactant coating enzyme, 1-2 parts by weight of fabric softener, 1-5 parts by weight of plant-derived antibacterial ingredient and 2-3 parts by weight of alkaline additive at a speed of 200 r / min-300 r / min for 10 min-15 min.

[0023] Compared with the prior art, the beneficial effects of the present invention are as follows:

[0024] This invention uses anionic surfactants with good cleaning and degradation properties, bioenzymes, fabric softeners, plant-derived antibacterial components, and alkaline additives in a dry mixture, aiming to achieve cleaning and sterilization through the synergistic effect of the components. However, in practical applications, the results have been found to be poor. Therefore, this invention replaces the anionic surfactant with a biodegradable and metal salt-resistant nonionic surfactant. It then first oxidizes the nonionic surfactant to generate functional aldehyde groups, thus obtaining an oxidized surfactant. The role of the aldehyde group is to enable the subsequent coating of the bioenzyme to form a powdered surfactant-coated enzyme. The cross-linking of the aldehyde group with the amino group creates a high-temperature-resistant Schiff base structure. The synergistic effect of the coating structure and the Schiff base structure protects the bioenzyme from the effects of high temperatures on its activity during drying. Furthermore, the Schiff base structure can be hydrolyzed to release the bioenzyme. Next, a Gemini surfactant is prepared by cross-linking the linker ethylenediamine with the aldehyde-containing oxidized surfactant. The construction of the Gemini surfactant helps reduce surface tension, further lowering the critical micelle concentration, thereby improving the surface activity of the surfactant and enhancing the cleaning effect. However, in actual cleaning, it was found that Gemini surfactants also generated more foam. If the foam is not rinsed off, it can cause objects to harden, cause itching when in contact with skin, and easily lead to off-flavors. High foam levels also result in wasted water, electricity, and time, leading to high costs. Therefore, a modified Gemini surfactant was obtained by using a crosslinking agent, divinyl sulfone, to attach a compound with a polyhydroxybenzene ring to the hydroxyl group of the Gemini surfactant. The polyhydroxybenzene ring compound inserts its large-volume benzene ring structure into the Gemini surfactant, disrupting the tightly packed structure of the Gemini surfactant in water, thereby effectively reducing foam. Furthermore, the benzene ring can improve the stability of the coating structure through π-π stacking, making it less prone to disintegration in high-temperature environments. In addition, the polyhydroxybenzene ring compound can form hydrogen bonds with plant-derived antibacterial components through its carboxyl and hydroxyl groups, which helps to weaken the hydrogen bond formation between the plant-derived antibacterial components and the coating structure constructed by the Gemini surfactant, thus improving the stability of the coating structure and enhancing the encapsulation stability of biological enzymes. By modifying the hydrogen bonding between Gemini surfactant and bio-enzyme, the bio-enzyme is coated and then dried at high temperature to obtain a powdered surfactant-coated enzyme. The bio-enzyme helps to enhance the cleaning effect of the modified Gemini surfactant. Finally, the surfactant-coated enzyme, fabric softener, plant-derived antibacterial ingredients, and alkaline additives are dry-mixed to obtain a composite disinfectant cleaning powder. This composite disinfectant cleaning powder has good detergency and bactericidal effects, and low foaming, so that no additional rinsing is required after the cleaning process, reducing water consumption and cleaning time, and is non-irritating to the skin. Detailed Implementation

[0025] The technical solution of the present invention will be clearly and completely described below through embodiments. Obviously, the described embodiments are only a part of the embodiments of the present invention, and not all of them. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.

[0026] Unless otherwise stated, all raw materials and reagents used in this invention are commercially available or can be prepared by known methods.

[0027] Preparation Example 1

[0028] The preparation process of surfactant-coated enzymes is as follows:

[0029] 10 parts by weight of tea saponin and 200 parts by weight of deionized water were weighed and mixed until dissolved and evenly dispersed. Then, 10 parts by weight of sodium periodate were added and the mixture was placed in a water bath at 25°C and protected from light. The mixture was then stirred at 200 rpm for 40 min. After the reaction was completed, 20 parts by weight of ethylene glycol were added for quenching. The mixture was then poured into a dialysis bag with a molecular weight cutoff of 500 Da and dialyzed with deionized water for 2 days. The retained solution in the bag was then evaporated by rotary evaporation to obtain the oxidizing surfactant. 1 part by weight of ethylenediamine and 100 parts by weight of anhydrous ethanol were weighed and mixed until evenly dissolved. Then, 7 parts by weight of the oxidizing surfactant were added and transferred to a water bath at 25°C. The stirring speed was adjusted to 150 rpm and the reaction was continued for 24 h. After the reaction was completed, the solution was poured into a dialysis bag with a molecular weight cutoff of 500 Da and treated with deionized water for 1 day. Then, the retained solution in the bag was evaporated by rotary evaporation to obtain Gemini surfactant. 1 part by weight of Gemini surfactant, 0.1 part by weight of divinyl sulfone, 0.5 part by weight of quercetin and 20 parts by weight of anhydrous acetone were weighed and mixed and dispersed by ultrasonic power of 300W for 15 min to make the mixture uniform. Then, the pH was adjusted to 9 with ammonia water and then transferred to a water bath at 25°C and stirred at 200 r / min for 1 h. After the reaction was complete, 30 parts by weight of deionized water were added and stirred for 10 minutes. The mixture was then allowed to stand for 30 minutes to allow complete separation, and the aqueous phase was collected. The entire aqueous phase was poured into a dialysis bag with a molecular weight cutoff of 1000 Da. The bag was treated with deionized water for 2 days. The retained solution was then removed by rotary evaporation to obtain the Gemini surfactant. Two parts by weight of the modified Gemini surfactant and one part by weight of a bioenzyme (composed of one part by weight of an alkaline protease with an enzyme activity of 200 U / mg and one part by weight of an enzyme with an enzyme activity of 100 U / mg) were weighed. (A mixture of mg lipase and 1 part by weight of cellulose with an enzyme activity of 20 U / mg) and 30 parts by weight of deionized water were mixed and placed in a low-temperature stirrer at 6°C and stirred at 100 r / min for 20 h to obtain a coated enzyme dispersion. The inlet air temperature of the spray dryer was first raised to 110°C and the outlet air temperature reached 55°C by an electric heating system. The coated enzyme dispersion was then fed into the spray dryer at a feed rate of 8 mL / min for spray drying. The powder was then collected, sealed and stored to obtain the surfactant-coated enzyme.

[0030] Preparation Example 2

[0031] The preparation process of surfactant-coated enzymes is as follows:

[0032] 10 parts by weight of tea saponin and 200 parts by weight of deionized water were weighed and mixed until dissolved and evenly dispersed. Then, 12 parts by weight of sodium periodate were added and the mixture was placed in a water bath at 25°C and protected from light. The mixture was then stirred at 200 rpm for 45 min. After the reaction was completed, 24 parts by weight of ethylene glycol were added for quenching. The mixture was then poured into a dialysis bag with a molecular weight cutoff of 500 Da and dialyzed with deionized water for 2 days. The retained solution in the bag was then evaporated by rotary evaporation to obtain the oxidized surfactant. 1 part by weight of ethylenediamine and 100 parts by weight of anhydrous ethanol were weighed and mixed until evenly dissolved. Then, 7.5 parts by weight of the oxidized surfactant were added and the mixture was transferred to a water bath at 25°C. The stirring speed was adjusted to 150 rpm and the reaction was continued for 26 h. After the reaction was completed, the solution was poured into a dialysis bag with a molecular weight cutoff of 500 Da and treated with deionized water for 1 day. Then, the retained solution in the bag was evaporated by rotary evaporation to obtain Gemini surfactant. 1 part by weight of Gemini surfactant, 0.15 parts by weight of divinyl sulfone, 0.6 parts by weight of quercetin and 20 parts by weight of anhydrous acetone were weighed and mixed and dispersed by ultrasonic power of 300W for 15 min to make the mixture uniform. Then, the pH was adjusted to 9 with ammonia water and then transferred to a water bath at 25°C and stirred at 200 r / min for 1.5 h. After the reaction was complete, 30 parts by weight of deionized water were added and stirred for 10 minutes. The mixture was then allowed to stand for 30 minutes to allow complete separation, and the aqueous phase was collected. The entire aqueous phase was poured into a dialysis bag with a molecular weight cutoff of 1000 Da. The bag was treated with deionized water for 2 days. The retained solution was then removed by rotary evaporation to obtain the Gemini surfactant. Two parts by weight of the modified Gemini surfactant and 1.2 parts by weight of the bioenzyme (composed of 1 part by weight of alkaline protease with an enzyme activity of 200 U / mg and 1 part by weight of enzyme with an enzyme activity of 100 U / mg) were weighed. The mixture of 1 mg / mg lipase and 1 part by weight of cellulose with an enzyme activity of 20 U / mg, and 28 parts by weight of deionized water were placed in a low-temperature stirrer at 6°C and stirred at 100 r / min for 21 h to obtain a coated enzyme dispersion. The inlet air temperature of the spray dryer was first raised to 110°C and the outlet air temperature reached 55°C through an electric heating system. The coated enzyme dispersion was then fed into the spray dryer at a feed rate of 8 mL / min for spray drying. The powder was then collected, sealed and stored to obtain the surfactant-coated enzyme.

[0033] Preparation Example 3

[0034] The preparation process of surfactant-coated enzymes is as follows:

[0035] 10 parts by weight of tea saponin and 250 parts by weight of deionized water were weighed and mixed until dissolved and evenly dispersed. Then, 12 parts by weight of sodium periodate were added and the mixture was placed in a water bath at 25°C and protected from light. The mixture was then stirred at 200 rpm for 50 min. After the reaction was completed, 24 parts by weight of ethylene glycol were added for quenching. The mixture was then poured into a dialysis bag with a molecular weight cutoff of 500 Da and dialyzed with deionized water for 2 days. The retained solution in the bag was then evaporated by rotary evaporation to obtain the oxidized surfactant. 1.5 parts by weight of ethylenediamine and 120 parts by weight of anhydrous ethanol were weighed and mixed until evenly dissolved. Then, 7.5 parts by weight of the oxidized surfactant were added and the mixture was transferred to a water bath at 30°C. The stirring speed was adjusted to 150 rpm and the reaction was continued for 26 h. After the reaction was completed, the solution was poured into a dialysis bag with a molecular weight cutoff of 500 Da and treated with deionized water for 1 day. Then, the retained solution in the bag was evaporated by rotary evaporation to obtain Gemini surfactant. 1 part by weight of Gemini surfactant, 0.15 parts by weight of divinyl sulfone, 0.7 parts by weight of quercetin and 22 parts by weight of anhydrous acetone were weighed and mixed. The mixture was then dispersed by ultrasonic power of 300W for 15 minutes to make it uniform. The pH was then adjusted to 9.5 with ammonia water and then transferred to a water bath at 30°C. The mixture was stirred at 200 r / min for 1.5 hours. After the reaction was complete, 30 parts by weight of deionized water were added and stirred for 10 minutes. The mixture was then allowed to stand for 30 minutes to allow complete separation, and the aqueous phase was collected. The entire aqueous phase was poured into a dialysis bag with a molecular weight cutoff of 1000 Da. The bag was treated with deionized water for 2 days. The retained solution was then removed by rotary evaporation to obtain the Gemini surfactant. 2.5 parts by weight of the modified Gemini surfactant and 1.2 parts by weight of the bioenzyme (composed of 1 part by weight of alkaline protease with an enzyme activity of 200 U / mg and 1 part by weight of enzyme with an enzyme activity of 100...) were weighed. The mixture of lipase (1 part by weight with an enzyme activity of 20 U / mg) and cellulose (1 part by weight) with 26 parts by weight of deionized water was placed in a low-temperature stirrer at 5°C and stirred at 100 r / min for 22 h to obtain a coated enzyme dispersion. The inlet air temperature of the spray dryer was first raised to 115°C and the outlet air temperature reached 60°C by an electric heating system. The coated enzyme dispersion was then fed into the spray dryer at a feed rate of 9 mL / min for spray drying. The powder was then collected, sealed and stored to obtain the surfactant-coated enzyme.

[0036] Preparation Example 4

[0037] The preparation process of surfactant-coated enzymes is as follows:

[0038] 10 parts by weight of tea saponin and 300 parts by weight of deionized water were weighed and mixed until dissolved and evenly dispersed. Then, 14 parts by weight of sodium periodate were added and the mixture was placed in a water bath at 30°C and protected from light. The mixture was then stirred at 200 rpm for 55 min. After the reaction was completed, 28 parts by weight of ethylene glycol were added for quenching. The mixture was then poured into a dialysis bag with a molecular weight cutoff of 500 Da and dialyzed with deionized water for 2 days. The retained solution in the bag was then evaporated by rotary evaporation to obtain the oxidizing surfactant. 1.5 parts by weight of ethylenediamine and 120 parts by weight of anhydrous ethanol were weighed and mixed until evenly dissolved. Then, 8 parts by weight of the oxidizing surfactant were added and the mixture was transferred to a water bath at 30°C. The stirring speed was adjusted to 150 rpm and the reaction was continued for 28 h. After the reaction was completed, the solution was poured into a dialysis bag with a molecular weight cutoff of 500 Da and treated with deionized water for 1 day. Then, the retained solution in the bag was evaporated by rotary evaporation to obtain Gemini surfactant. 1 part by weight of Gemini surfactant, 0.2 parts by weight of divinyl sulfone, 0.8 parts by weight of quercetin and 24 parts by weight of anhydrous acetone were weighed and mixed and dispersed by ultrasonic power of 300W for 15 minutes to make the mixture uniform. Then, the pH was adjusted to 9.5 with ammonia water and then transferred to a water bath at 30°C and stirred at 200 r / min for 2 hours. After the reaction was complete, 30 parts by weight of deionized water were added and stirred for 10 minutes. The mixture was then allowed to stand for 30 minutes to allow complete separation, and the aqueous phase was collected. The entire aqueous phase was poured into a dialysis bag with a molecular weight cutoff of 1000 Da. The bag was treated with deionized water for 2 days. The retained solution was then removed by rotary evaporation to obtain the Gemini surfactant. 2.5 parts by weight of the modified Gemini surfactant and 1.4 parts by weight of the bioenzyme (composed of 1 part by weight of alkaline protease with an enzyme activity of 200 U / mg and 1 part by weight of enzyme activity of 100...) were weighed. The mixture of lipase (1 part by weight with an enzyme activity of 20 U / mg) and cellulose (1 part by weight) with 26 parts by weight of deionized water was placed in a low-temperature stirrer at 5°C and stirred at 100 r / min for 23 h to obtain a coated enzyme dispersion. The inlet air temperature of the spray dryer was first raised to 115°C and the outlet air temperature reached 60°C through an electric heating system. The coated enzyme dispersion was then fed into the spray dryer at a feed rate of 9 mL / min for spray drying. The powder was then collected, sealed and stored to obtain the surfactant-coated enzyme.

[0039] Preparation Example 5

[0040] The preparation process of surfactant-coated enzymes is as follows:

[0041] 10 parts by weight of tea saponin and 300 parts by weight of deionized water were weighed and mixed until dissolved and evenly dispersed. Then, 15 parts by weight of sodium periodate were added and the mixture was placed in a water bath at 30°C and protected from light. The mixture was then stirred at 200 rpm for 60 min. After the reaction was completed, 30 parts by weight of ethylene glycol were added for quenching. The mixture was then poured into a dialysis bag with a molecular weight cutoff of 500 Da and dialyzed with deionized water for 2 days. The retained solution in the bag was then evaporated by rotary evaporation to obtain the oxidizing surfactant. 2 parts by weight of ethylenediamine and 150 parts by weight of anhydrous ethanol were weighed and mixed until evenly dissolved. Then, 8 parts by weight of the oxidizing surfactant were added and transferred to a water bath at 30°C. The stirring speed was adjusted to 150 rpm and the reaction was continued for 30 h. After the reaction was completed, the solution was poured into a dialysis bag with a molecular weight cutoff of 500 Da and treated with deionized water for 1 day. Then, the retained solution in the bag was evaporated by rotary evaporation to obtain Gemini surfactant. 1 part by weight of Gemini surfactant, 0.2 parts by weight of divinyl sulfone, 0.9 parts by weight of quercetin and 25 parts by weight of anhydrous acetone were weighed and mixed and dispersed by ultrasonic power of 300W for 15 min to make the mixture uniform. Then, the pH was adjusted to 9.5 with ammonia water and then transferred to a water bath at 30℃ and stirred at 200 r / min for 2 h. After the reaction was complete, 30 parts by weight of deionized water were added and stirred for 10 minutes. The mixture was then allowed to stand for 30 minutes to allow complete separation, and the aqueous phase was collected. The entire aqueous phase was poured into a dialysis bag with a molecular weight cutoff of 1000 Da. The bag was treated with deionized water for 2 days. The retained solution was then removed by rotary evaporation to obtain the Gemini surfactant. 3 parts by weight of the modified Gemini surfactant and 1.5 parts by weight of the bioenzyme (composed of 1 part by weight of alkaline protease with an enzyme activity of 200 U / mg and 1 part by weight of enzyme with an enzyme activity of 100 U / mg) were weighed. The mixture of 1 mg / mg lipase and 1 part by weight of cellulose with an enzyme activity of 20 U / mg, and 25 parts by weight of deionized water were placed in a low-temperature stirrer at 5°C and stirred at 100 r / min for 24 h to obtain a coated enzyme dispersion. The inlet air temperature of the spray dryer was first raised to 120°C and the outlet air temperature reached 60°C through an electric heating system. The coated enzyme dispersion was then fed into the spray dryer at a feed rate of 9 mL / min for spray drying. The powder was then collected, sealed and stored to obtain the surfactant-coated enzyme.

[0042] Preparation Example 6

[0043] The preparation process of surfactant-coated enzymes is as follows:

[0044] In Preparation Example 5, the tea saponin was replaced with the nonionic surfactant alkyl glycoside APG0810. The rest of the preparation process was the same as in Preparation Example 5. It was found that the wall adhesion phenomenon was very serious when spray drying was performed, and it was impossible to prepare it into powder form. Therefore, it was impossible to dry mix it with the fabric softener and plant-derived antibacterial ingredients. This may be because although alkyl glycosides are nonionic surfactants, they are in liquid or paste form under normal conditions. Without encapsulation pretreatment, direct high-temperature drying cannot form solid powder particles.

[0045] Preparation Example 7

[0046] The preparation process of surfactant-coated enzymes is as follows:

[0047] Three parts by weight of tea saponin, 1.5 parts by weight of biological enzyme (composed of 1 part by weight of alkaline protease with an enzyme activity of 200 U / mg, 1 part by weight of lipase with an enzyme activity of 100 U / mg, and 1 part by weight of cellulose with an enzyme activity of 20 U / mg) and 25 parts by weight of deionized water were weighed and mixed. The mixture was placed in a low-temperature stirrer at 5°C and stirred at 100 r / min for 24 h to obtain a coated enzyme dispersion. The inlet air temperature of the spray dryer was first raised to 120°C and the outlet air temperature reached 60°C through an electric heating system. The coated enzyme dispersion was then fed into the spray dryer at a feed rate of 9 mL / min for spray drying. The powder was then collected, sealed, and stored to obtain the surfactant-coated enzyme.

[0048] Preparation Example 8

[0049] The preparation process of surfactant-coated enzymes is as follows:

[0050] In Preparation Example 5, ethylenediamine was replaced with 1,6-hexanediamine, and the rest of the preparation process remained the same as in Preparation Example 5.

[0051] Preparation Example 9

[0052] The preparation process of surfactant-coated enzymes is as follows:

[0053] Weigh 10 parts by weight of tea saponin and 300 parts by weight of deionized water, mix and stir to dissolve and disperse evenly, then add 18 parts by weight of sodium periodate and place in a water bath at 30°C to protect it from light, then stir at 200 r / min for 90 min. The rest of the preparation process is the same as in Preparation Example 5.

[0054] Preparation Example 10

[0055] The preparation process of surfactant-coated enzymes is as follows:

[0056] In Preparation Example 5, quercetin was replaced with chlorogenic acid, and the rest of the preparation process remained the same as in Preparation Example 5.

[0057] Preparation Example 11

[0058] The preparation process of surfactant-coated enzymes is as follows:

[0059] In Preparation Example 5, the amount of modified Gemini surfactant was increased to 6 parts by weight and the amount of bio-enzyme was increased to 3 parts by weight. The rest of the preparation process was the same as in Preparation Example 5. It was found that during spray drying, the wall adhesion phenomenon was high and the nozzle clogging phenomenon occurred, resulting in preparation failure. This may be because the high solid content in this system may lead to high viscosity, incomplete evaporation of water and easy sticking together, which in turn affects the drying process.

[0060] Preparation Example 12

[0061] The preparation process of surfactant-coated enzymes is as follows:

[0062] The inlet air temperature in Preparation Example 5 was increased to 140°C, while the rest of the preparation process remained the same as in Preparation Example 5.

[0063] Preparation Example 13

[0064] The preparation process of surfactant-coated enzymes is as follows:

[0065] Weigh 3 parts by weight of the Gemini surfactant obtained in Preparation Example 5, 1.5 parts by weight of the bio-enzyme (composed of 1 part by weight of alkaline protease with an enzyme activity of 200 U / mg, 1 part by weight of lipase with an enzyme activity of 100 U / mg and 1 part by weight of cellulose with an enzyme activity of 20 U / mg), and 25 parts by weight of deionized water. Mix the mixture and place it in a low-temperature stirrer at 5°C. Stir at 100 r / min for 24 h to obtain a coated enzyme dispersion. First, raise the inlet air temperature of the spray dryer to 120°C and the outlet air temperature to 60°C through an electric heating system. Then, feed the coated enzyme dispersion into the spray dryer at a feed rate of 9 mL / min for spray drying. Finally, collect the powder, seal and store it to obtain the surfactant-coated enzyme.

[0066] Example 1

[0067] A method for preparing a bio-based low-foaming, high-efficiency composite disinfectant cleaning powder, specifically including the following steps:

[0068] 15 parts by weight of the surfactant coating enzyme obtained in Preparation Example 1, 1 part by weight of softening powder RL-118, 1 part by weight of honeysuckle extract and 2 parts by weight of alkaline auxiliary agent (composed of 1 part by weight of sodium carbonate and 1 part by weight of sodium metasilicate) were placed in a vacuum drying oven at 40°C for 12 hours to ensure the system was as dry as possible. Then they were put into a mixer and dry mixed at 200 r / min for 15 minutes to obtain a composite disinfection and cleaning powder.

[0069] Example 2

[0070] A method for preparing a bio-based low-foaming, high-efficiency composite disinfectant cleaning powder, specifically including the following steps:

[0071] 16 parts by weight of the surfactant coating enzyme obtained in Preparation Example 2, 1.5 parts by weight of the softening powder RL-118, 2 parts by weight of honeysuckle extract and 2 parts by weight of alkaline auxiliary agent (composed of 1 part by weight of sodium carbonate and 1 part by weight of sodium metasilicate) were placed in a vacuum drying oven at 40°C for 12 hours to ensure the system was as dry as possible. Then they were placed together in a mixer and dry mixed at 200 r / min for 14 minutes to obtain a composite disinfection and cleaning powder.

[0072] Example 3

[0073] A method for preparing a bio-based low-foaming, high-efficiency composite disinfectant cleaning powder, specifically including the following steps:

[0074] 17 parts by weight of the surfactant coating enzyme obtained in Preparation Example 3, 1.5 parts by weight of the softening powder RL-118, 3 parts by weight of honeysuckle extract and 2.5 parts by weight of alkaline auxiliary agent (composed of 1 part by weight of sodium carbonate and 1 part by weight of sodium metasilicate) were placed in a vacuum drying oven at 40°C for 12 hours to ensure the system was as dry as possible. Then they were put into a mixer and dry mixed at 200 r / min for 13 minutes to obtain a composite disinfection and cleaning powder.

[0075] Example 4

[0076] A method for preparing a bio-based low-foaming, high-efficiency composite disinfectant cleaning powder, specifically including the following steps:

[0077] 18 parts by weight of the surfactant coating enzyme obtained in Preparation Example 4, 2 parts by weight of softening powder RL-128, 4 parts by weight of rosemary extract and 2.5 parts by weight of alkaline auxiliary agent (composed of 1 part by weight of sodium carbonate and 1 part by weight of sodium metasilicate) were placed in a vacuum drying oven at 40°C for 12 hours to ensure the system was as dry as possible. Then they were put into a mixer and dry mixed at 300 r / min for 12 minutes to obtain a composite disinfection and cleaning powder.

[0078] Example 5

[0079] A method for preparing a bio-based low-foaming, high-efficiency composite disinfectant cleaning powder, specifically including the following steps:

[0080] 19 parts by weight of the surfactant coating enzyme obtained in Preparation Example 5, 2 parts by weight of softening powder RL-128, 5 parts by weight of rosemary extract and 3 parts by weight of alkaline auxiliary agent (composed of 1 part by weight of sodium carbonate and 1 part by weight of sodium metasilicate) were placed in a vacuum drying oven at 40°C for 12 hours to ensure the system was as dry as possible. Then they were put into a mixer and dry mixed at 300 r / min for 15 minutes to obtain a composite disinfection and cleaning powder.

[0081] Comparative Example 1

[0082] A method for preparing a bio-based low-foaming, high-efficiency composite disinfectant cleaning powder, specifically including the following steps:

[0083] 19 parts by weight of the surfactant coating enzyme obtained in Preparation Example 7, 2 parts by weight of softening powder RL-128, 5 parts by weight of rosemary extract and 3 parts by weight of alkaline auxiliary agent (composed of 1 part by weight of sodium carbonate and 1 part by weight of sodium metasilicate) were placed in a vacuum drying oven at 40°C for 12 hours to ensure the system was as dry as possible. Then they were placed together in a mixer and dry mixed at 300 r / min for 15 minutes to obtain a composite disinfection and cleaning powder.

[0084] Comparative Example 2

[0085] A method for preparing a bio-based low-foaming, high-efficiency composite disinfectant cleaning powder, specifically including the following steps:

[0086] 19 parts by weight of the surfactant coating enzyme obtained in Preparation Example 8, 2 parts by weight of softening powder RL-128, 5 parts by weight of rosemary extract and 3 parts by weight of alkaline auxiliary agent (composed of 1 part by weight of sodium carbonate and 1 part by weight of sodium metasilicate) were placed in a vacuum drying oven at 40°C for 12 hours to ensure the system was as dry as possible. Then they were put into a mixer and dry mixed at 300 r / min for 15 minutes to obtain a composite disinfection and cleaning powder.

[0087] Comparative Example 3

[0088] A method for preparing a bio-based low-foaming, high-efficiency composite disinfectant cleaning powder, specifically including the following steps:

[0089] 19 parts by weight of the surfactant coating enzyme obtained in Preparation Example 9, 2 parts by weight of softening powder RL-128, 5 parts by weight of rosemary extract and 3 parts by weight of alkaline auxiliary agent (composed of 1 part by weight of sodium carbonate and 1 part by weight of sodium metasilicate) were placed in a vacuum drying oven at 40°C for 12 hours to ensure the system was as dry as possible. Then they were placed together in a mixer and dry mixed at 300 r / min for 15 minutes to obtain a composite disinfection and cleaning powder.

[0090] Comparative Example 4

[0091] A method for preparing a bio-based low-foaming, high-efficiency composite disinfectant cleaning powder, specifically including the following steps:

[0092] 19 parts by weight of the surfactant coating enzyme obtained in Preparation Example 10, 2 parts by weight of the softening powder RL-128, 5 parts by weight of rosemary extract and 3 parts by weight of alkaline auxiliary agent (composed of 1 part by weight of sodium carbonate and 1 part by weight of sodium metasilicate) were placed in a vacuum drying oven at 40°C for 12 hours to ensure the system was as dry as possible. Then they were put into a mixer and dry mixed at 300 r / min for 15 minutes to obtain a composite disinfection and cleaning powder.

[0093] Comparative Example 5

[0094] A method for preparing a bio-based low-foaming, high-efficiency composite disinfectant cleaning powder, specifically including the following steps:

[0095] 19 parts by weight of the surfactant coating enzyme obtained in Preparation Example 12, 2 parts by weight of softening powder RL-128, 5 parts by weight of rosemary extract and 3 parts by weight of alkaline auxiliary agent (composed of 1 part by weight of sodium carbonate and 1 part by weight of sodium metasilicate) were placed in a vacuum drying oven at 40°C for 12 hours to ensure the system was as dry as possible. Then they were placed together in a mixer and dry mixed at 300 r / min for 15 minutes to obtain a composite disinfection and cleaning powder.

[0096] Comparative Example 6

[0097] A method for preparing a bio-based low-foaming, high-efficiency composite disinfectant cleaning powder, specifically including the following steps:

[0098] 19 parts by weight of the surfactant coating enzyme obtained in Preparation Example 13, 2 parts by weight of the softening powder RL-128, 5 parts by weight of rosemary extract and 3 parts by weight of alkaline auxiliary agent (composed of 1 part by weight of sodium carbonate and 1 part by weight of sodium metasilicate) were placed in a vacuum drying oven at 40°C for 12 hours to ensure the system was as dry as possible. Then they were placed together in a mixer and dry mixed at 300 r / min for 15 minutes to obtain a composite disinfection and cleaning powder.

[0099] Comparative Example 7

[0100] A method for preparing a bio-based low-foaming, high-efficiency composite disinfectant cleaning powder, specifically including the following steps:

[0101] 9.5 parts by weight of nonionic surfactant MES-86, 9.5 parts by weight of bio-enzyme (composed of 1 part by weight of alkaline protease with an enzyme activity of 200 U / mg, 1 part by weight of lipase with an enzyme activity of 100 U / mg and 1 part by weight of cellulose with an enzyme activity of 20 U / mg), 2 parts by weight of softening powder RL-128, 5 parts by weight of rosemary extract and 3 parts by weight of alkaline auxiliary agent (composed of 1 part by weight of sodium carbonate and 1 part by weight of sodium metasilicate) were placed in a vacuum drying oven at 40°C for 12 hours to ensure the system was as dry as possible. Then they were put into a mixer and dry-mixed at 300 r / min for 15 minutes to obtain a composite disinfection and cleaning powder.

[0102] Comparative Example 8

[0103] A method for preparing a bio-based low-foaming, high-efficiency composite disinfectant cleaning powder, specifically including the following steps:

[0104] 19 parts by weight of the surfactant coating enzyme obtained in Preparation Example 5, 4 parts by weight of softening powder RL-128, 5 parts by weight of rosemary extract and 3 parts by weight of alkaline auxiliary agent (composed of 1 part by weight of sodium carbonate and 1 part by weight of sodium metasilicate) were placed in a vacuum drying oven at 40°C for 12 hours to ensure the system was as dry as possible. Then they were put into a mixer and dry mixed at 300 r / min for 15 minutes to obtain a composite disinfection and cleaning powder.

[0105] The composite disinfectant cleaning powder obtained in Examples 1-5 and Comparative Examples 1-8 was mixed with tap water at a weight ratio of 1:100 to obtain a mixture. Then, a total volume of 500 mL of the mixture was poured into a 1 L graduated cylinder, sealed with plastic film, and then shaken back and forth for 5 minutes. After standing, the mixture was observed and the foam was recorded by reading the scale line. The results are shown in Table 1 below.

[0106] Table 1 Foaming situation

[0107]

[0108] Mix 1L soybean oil, 10 eggs, 1L red wine, 1L milk, 1L grape juice, and 1kg tomato sauce to form a mixed oil stain. Then, soak 5 adult white T-shirts in the mixed oil stain for 5 minutes. After soaking, remove them and put them in a washing machine. Set the washing time to 30 minutes and the number of rinses to 2. Add 10g of the compound disinfectant cleaning powder obtained in Examples 1-5 and Comparative Examples 1-8 per kilogram of clothing weight. Then, start the washing program in the non-heating mode. After the washing is finished, take out the clothes and observe whether there are any residual stains. If there are any residues, the cleaning has failed. Add water and rub the washed clothes. If foam appears, rinse again with the rinsing program until there is no foam after adding water and rubbing. Record the number of extra rinses. The cleaning effect is shown in Table 2. Set the above non-heating mode to 60℃ hot water mode, and keep the rest unchanged. The cleaning effect is shown in Table 3. In the table, " / " indicates that there are residual stains and no rinsing is performed.

[0109] Table 2 Cleaning effect with room temperature water

[0110]

[0111] Table 3 Cleaning effect of 60℃ hot water

[0112]

[0113] The composite disinfectant cleaning powder obtained in Examples 1-5 and Comparative Examples 1-8 was mixed with tap water at a weight ratio of 1:20 to obtain a mixture. Then, a white T-shirt was placed in the mixture and rubbed by hand for 20 minutes. After rubbing, the hands were rinsed with tap water. The condition of the hands, such as dryness, itching, tightness, and small red spots, was recorded. The results are shown in Table 4 below.

[0114] Table 4 Skin Sensitivity

[0115]

[0116] Antibacterial test:

[0117] Take 5g of the composite disinfectant cleaning powder obtained in Examples 1-5 and Comparative Examples 1-8, respectively, and mix it with 5g of peptone, 3g of beef extract powder, 5g of sodium chloride, and 15g of agar. Add water and heat to mix evenly. Adjust the pH to 7.0, then bring the volume to 1L. After sterilization, pour the mixture into plates to obtain the culture medium. OD 600 Escherichia coli, Staphylococcus aureus, and Candida albicans bacterial suspensions at 0.7 were inoculated onto the surface of the culture medium and then placed in an incubator at 37°C for 24 hours. The presence of colonies was observed, and the results are shown in Table 5 below.

[0118] Table 5 Antibacterial properties

[0119]

[0120] The following conclusions can be drawn from Tables 1-5 above:

[0121] (1) As can be seen from Examples 1 to 5, the composite disinfectant cleaning powder prepared by the present invention has good decontamination and sterilization effects, and low foaming amount, so that no additional rinsing is required after the cleaning process, reducing water consumption and cleaning time, and is non-irritating to the skin.

[0122] (2) Comparative Example 1 shows that the prepared composite disinfectant cleaning powder has poor cleaning effect, high foam content, and long rinsing time. This may be because the biological enzyme is encapsulated by hydrogen bonding between tea saponin and biological enzyme. Although a coating structure can be formed, it cannot be protected against high temperature, resulting in loss of activity of biological enzyme and poor cleaning effect. Furthermore, the foam content is not reduced by directly using unmodified tea saponin, which is not conducive to cleaning and water saving.

[0123] (3) Comparative Example 2 shows that the cleaning effect of the prepared composite disinfection and cleaning powder is poor. On the one hand, this may be because 1,6-hexanediamine has a longer carbon chain than ethylenediamine, which may lead to higher overall hydrophobicity and lower hydrophilicity after tea saponin modification due to the increase of hydrophobic carbon chain. On the other hand, the increase in hydrophobicity may lead to a poorer coating effect on hydrophilic biological enzymes, which may result in less coating of biological enzymes, thus hindering the cleaning effect in water.

[0124] (4) Comparative Example 3 shows that the cleaning effect of the prepared composite disinfectant cleaning powder is poor. This may be because, although tea saponin needs to rely on sodium periodate to oxidize and break down to produce aldehyde groups in this system, the amount of sodium periodate used and the oxidation time have an important impact on the structure of tea saponin. Excessive use and prolonged oxidation treatment may cause the structure of tea saponin to be over-oxidized and destroyed, which may lead to the loss of its own surface activity and thus the loss of cleaning effect. Relying solely on biological enzymes will result in poor effect.

[0125] (5) Comparative Example 4 shows that the prepared composite disinfectant cleaning powder has poor cleaning effect, poor foam reduction, and long rinsing time. This may be because chlorogenic acid lacks one benzene ring in its structure compared to quercetin. The rigid structure of the benzene ring can not only destroy the tightly packed structure of the surfactant in water, thereby reducing the foam, but also help improve the high temperature stability of the coating structure. The lack of benzene ring may make its coating structure unstable in the high temperature environment, which is not conducive to the stability of the biological enzyme coating and ultimately affects the cleaning effect.

[0126] (6) Comparative Example 5 shows that the cleaning effect of the prepared composite disinfection and cleaning powder is poor. This may be because although increasing the air inlet temperature helps to shorten the drying time and improve efficiency, in this system, there may be fewer vicinal diols that can form Schiff base structures in tea saponins, resulting in fewer Schiff base structures. Therefore, although the drying time can be shortened and the drying efficiency can be improved at higher air inlet temperatures, the high-temperature protection constructed in this system may not be able to withstand higher temperatures, thus damaging the activity of biological enzymes and weakening the cleaning effect.

[0127] (7) Comparative Example 6 shows that the prepared composite disinfectant cleaning powder has a high amount of foam, requires more rinsing times, and takes a longer time to clean. This may be because although the Gemini surfactant constructed by linker ethylenediamine has a lower surface tension, which improves the cleaning effect, the low surface tension can easily increase the amount of foam and the stability of the foam, which in turn leads to more foam during the cleaning process, which can easily increase the amount of water used to rinse the foam and make the cleaning time-consuming.

[0128] (8) Comparative Example 7 shows that the prepared composite disinfectant cleaning powder has a poor cleaning effect, high foam content, many rinsing times, and a longer cleaning cycle. This may be because when used directly, on the one hand, the metal salts in the water are easy to combine with the anionic surfactant, thus weakening the surfactant's effect. On the other hand, the softener used is a cationic softener with good softening effect, which may easily combine with the biological enzymes by electrostatic attraction, causing the biological enzymes to lose their activity. Although increasing the water temperature helps to clean stains, the higher water temperature will reduce the activity of the enzymes, thus reducing the effect of the biological enzymes. In addition, the high foam content leads to a large amount of water used for cleaning.

[0129] (9) Comparative Example 8 shows that the cleaning effect of the prepared composite disinfectant cleaning powder is poor. This may be because although the cationic softener RL-128 has excellent softening effect, the cationic softener has a strong penetration binding effect. In this system, the surfactant coating enzyme structure may be destroyed by penetration swelling due to excessive use, which is not conducive to improving the cleaning effect.

[0130] The embodiments described above provide a detailed explanation of the technical solutions and beneficial effects of the present invention. It should be understood that the above descriptions are merely specific embodiments of the present invention and are not intended to limit the present invention. Various changes and modifications can be made to the present invention without departing from its spirit and scope, and all such changes and modifications fall within the scope of the present invention as claimed.

Claims

1. A bio-based low-foaming, high-efficiency composite disinfectant and cleaning powder, characterized in that, The composite disinfectant and cleaning powder comprises the following raw materials in parts by weight: 15-19 parts by weight of surfactant coating enzyme, 1-2 parts by weight of fabric softener, 1-5 parts by weight of plant-derived antibacterial ingredient, and 2-3 parts by weight of alkaline additive.

2. The bio-based low-foaming, high-efficiency composite disinfectant and cleaning powder according to claim 1, characterized in that, The method for preparing the surfactant-coated enzyme includes the following steps: Surfactant, deionized water and sodium periodate were mixed in a weight ratio of 1:20~30:1~1.5 and protected from light. The mixture was then reacted at 25℃~30℃ for 40min~60min to obtain an oxidized surfactant. An oxidizing surfactant, a linker, and anhydrous ethanol are mixed in a weight ratio of 7-8:1-2:100-150 and reacted at 25℃-30℃ for 24-30 hours to obtain a Gemini surfactant. Gemini surfactant, crosslinking agent, polyhydroxybenzene ring compound and anhydrous acetone are mixed in a weight ratio of 1:0.1~0.2:0.5~0.9:20~25 and the pH is adjusted to 9~9.

5. Then the mixture is reacted at 25℃~30℃ for 1h~2h to obtain modified Gemini surfactant. A coated enzyme dispersion was obtained by mixing and stirring modified Gemini surfactant, biological enzyme and deionized water in a weight ratio of 2~3:1~1.5:25~30. The surfactant-coated enzyme was obtained by spray drying the coated enzyme dispersion.

3. The bio-based low-foaming, high-efficiency composite disinfectant and cleaning powder according to claim 2, characterized in that, The surfactant includes tea saponin.

4. The bio-based low-foaming, high-efficiency composite disinfectant and cleaning powder according to claim 2, characterized in that, The linker group includes ethylenediamine.

5. The bio-based low-foaming, high-efficiency composite disinfectant and cleaning powder according to claim 2, characterized in that, The crosslinking agent includes divinyl sulfone.

6. The bio-based low-foaming high-efficiency composite disinfectant and cleaning powder according to claim 2, characterized in that, The polyhydroxybenzene ring compound includes quercetin.

7. The bio-based low-foaming, high-efficiency composite disinfectant and cleaning powder according to claim 2, characterized in that, The bio-enzyme is composed of alkaline protease, lipase and cellulase in a weight ratio of 1:1:

1.

8. The bio-based low-foaming, high-efficiency composite disinfectant and cleaning powder according to claim 1, characterized in that, The fabric softener includes fabric softener RL-118 or fabric softener RL-128, the plant-derived antibacterial ingredient includes honeysuckle extract or rosemary extract, and the alkaline adjuvant is composed of sodium carbonate and sodium metasilicate in a weight ratio of 1:

1.

9. A method for preparing a bio-based low-foaming, high-efficiency composite disinfectant cleaning powder as described in any one of claims 1 to 8, characterized in that, The preparation method includes the following steps: The composite disinfectant and cleaning powder is obtained by dry mixing 15-19 parts by weight of surfactant coating enzyme, 1-2 parts by weight of fabric softener, 1-5 parts by weight of plant-derived antibacterial ingredient and 2-3 parts by weight of alkaline additive at a speed of 200 r / min-300 r / min for 10 min-15 min.

Images