Phyllanthus emblica extract, preparation method and application thereof

The amla extract prepared by solvent extraction and membrane filtration technology has solved the problem that the active ingredients of amla cannot effectively inhibit related enzymes in the existing technology, and has achieved a significant inhibitory effect, which has important pharmacological application potential.

CN122321023APending Publication Date: 2026-07-03GUANGZHOU HOSPITAL OF TRADITIONAL CHINESE MEDICINE
View PDF 0 Cites 0 Cited by

Patent Information

Application Number
CN202610617265.9
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2026-05-07
Publication Date
2026-07-03

AI Technical Summary

Technical Problem

In the existing technology, the extraction methods of active ingredients from Phyllanthus emblica have failed to effectively inhibit the activity of coronavirus main protease, transmembrane serine protease 2 and neuraminidase, which limits its application in the treatment of related diseases.

Method used

Using solvent extraction combined with membrane filtration technology, an extract of Phyllanthus emblica with a molecular weight of less than 1000D was prepared. High-purity Phyllanthus emblica extract was obtained through multi-stage membrane filtration and concentration, which was used to inhibit the activity of coronavirus main protease, transmembrane serine protease 2 and neuraminidase.

Benefits of technology

The prepared Phyllanthus emblica extract was significantly superior to that prepared by traditional methods, exhibiting stronger inhibitory effects on coronavirus main protease, transmembrane serine protease 2, and neuraminidase. It also showed good water solubility and significantly enhanced pharmacological activity, surpassing Corilagin reference standard.

✦ Generated by Eureka AI based on patent content.

Smart Images

  • Figure SMS_1
    Figure SMS_1
  • Figure SMS_2
    Figure SMS_2
  • Figure SMS_3
    Figure SMS_3
Patent Text Reader

Abstract

This invention discloses an extract of Phyllanthus emblica, its preparation method, and its application, relating to the field of traditional Chinese medicine technology. The preparation method of the Phyllanthus emblica extract includes the following steps: S1. Extracting Phyllanthus emblica with a solvent to obtain an extract; S2. Centrifuging the extract, collecting the supernatant, then filtering it through a membrane to obtain a filtrate with a molecular weight below 1000D, concentrating it, and drying it to obtain the Phyllanthus emblica extract. This invention uses membrane separation technology to prepare an Phyllanthus emblica extract that inhibits coronavirus main protease (Mpro / 3Clpro), transmembrane serine protease 2 (Tmprss2), and neuraminidase (NA).
Need to check novelty before this filing date? Find Prior Art