Preparation method of super-hydrophilic and antibacterial medical silica gel tube

By preparing a superhydrophilic antibacterial silicone tube, the problem of antibacterial properties of silicone catheters in a bacterial environment was solved, achieving a high safety and low cost antibacterial effect with an inhibition rate of up to 99.9%.

CN122321231APending Publication Date: 2026-07-03SUZHOU GANGYANG TECH CO LTD
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Patent Information

Application Number
CN202610435507.2
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2026-04-03
Publication Date
2026-07-03

AI Technical Summary

Technical Problem

In the existing technology, silicone catheters lack effective antibacterial properties in a sterile environment, which may lead to complications in patients. Furthermore, existing antibacterial agents have low heat resistance, are volatile, have poor safety, and have a short antibacterial time.

Method used

A superhydrophilic antibacterial silicone tube was prepared by treating it with a surface-active treatment solution and a mixed solution of composite antibacterial materials, then coating it with a nano-silver-loaded titanium dioxide-chitosan composite antibacterial material, and finally forming a polyacrylamide coating under ultraviolet light irradiation.

Benefits of technology

It achieves high safety and low cost in antibacterial silicone tubes. The antibacterial material coating is firm and not easy to fall off, with significant antibacterial effect and a bacteriostatic rate of up to 99.9%.

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Abstract

This invention discloses a method for preparing superhydrophilic antibacterial medical silicone tubing. The method involves preparing a silicone tubing surface-active treatment solution, immersing the formed silicone tubing in the solution heated to 45-55°C for 20-30 seconds, removing it, and allowing it to air dry. A composite antibacterial material mixture solution is then prepared. The surface-modified silicone tubing is immersed in the heated composite antibacterial material mixture solution for coating, then removed and air-dried. The treated silicone tubing is placed in a vulcanization chamber, and the silicone tubing with a pre-embedded initiator is immersed in an aqueous solution containing acrylamide and a water-soluble photoinitiator to obtain a silicone tubing with a polyacrylamide coating. This results in a superhydrophilic antibacterial silicone tubing with high safety and low cost. The composite antibacterial material is easy to prepare and does not easily oxidize or discolor. This preparation method ensures that the antibacterial material is firmly coated on the surface of the silicone tubing and does not easily fall off, resulting in low consumption of antibacterial material and low production cost.
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