Chitosan nanometer preparation loaded with extract of helianthemum songaricum and preparation method and application thereof
By loading Artemisia argyi petroleum ether extract onto chitosan nanocarriers, nanoparticles with a particle size of 150-350 nm and a Zeta potential of +35 mV were prepared. This solved the problems of poor stability and slow efficacy of Artemisia argyi extract in the control of Sclerotinia sclerotinia in rapeseed, and achieved a highly efficient, stable, and green control effect.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- SHAANXI HYBRID RAPE RES CENT
- Filing Date
- 2026-05-21
- Publication Date
- 2026-07-17
AI Technical Summary
Existing plant-derived pesticides have drawbacks in controlling sclerotinia stem rot in rapeseed, including poor stability, slow efficacy, and short duration of action. In particular, there is a lack of dedicated formulation solutions that can systematically address these issues when using the active ingredients of Artemisia annua extract.
Chitosan nanocarriers were used to load petroleum ether extract of Artemisia annua and nanoparticles were prepared by ion crosslinking. The nanoparticles had a size of 150-350 nm and a zeta potential of +35 mV, exhibiting high encapsulation efficiency and sustained-release properties. The preparation method included emulsification and ion gelation reactions.
It has achieved efficient and stable control of sclerotinia stem rot in rapeseed, with a potted plant control efficacy of 75.23%. In field trials, it is superior to the chemical control drug carbendazim, and it still has positive control efficacy, especially in the case of drug resistance, which meets the requirements of sustainable agriculture and green food production.
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