Microneedle patch and preparation method and application thereof
By introducing a mesoporous outer layer and a soluble inner layer structure into the microneedle patch, combined with sustained-release microcapsules, the problem of the inability of existing microneedles to release drugs is solved, achieving long-term slow release of drugs, which is suitable for the treatment of chronic diseases.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- HUNAN AGRI UNIV ANIMAL PHARMA
- Filing Date
- 2026-05-12
- Publication Date
- 2026-07-17
AI Technical Summary
Existing solid microneedles, hollow microneedles, coated microneedles, and soluble microneedles cannot achieve sustained drug release. In particular, soluble microneedles separate rapidly after being inserted into the skin, resulting in rapid drug delivery in a short period of time, which cannot meet the treatment needs of long-term medication or treatment with large fluctuations in drug concentration.
The microneedle patch design employs a mesoporous outer layer and a soluble inner layer structure. The mesoporous outer layer serves as the support structure for the microneedles and the drug release channel, while the inner layer contains sustained-release microcapsules. The slow release of the drug is restricted through the channels of the mesoporous outer layer, thereby achieving long-acting drug delivery.
It achieves slow drug release, making it suitable for long-term medication or treatment of chronic diseases with large fluctuations in drug concentration, thus improving drug efficiency and effectiveness.
Smart Images
Figure CN122398710A_ABST