Use of a mc4r antagonist for the prevention or treatment of cachexia, anorexia or anorexia nervosa
The drug prepared by MC4R antagonist compound 1 solves the problem of insufficient types of existing drugs, and achieves effective treatment and prevention of cachexia and anorexia, significantly improves symptoms caused by chemotherapy, increases appetite and weight, and reduces muscle and bone loss.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- CHANGCHUN GENESCIENCE PHARM CO LTD
- Filing Date
- 2026-05-14
- Publication Date
- 2026-07-17
AI Technical Summary
There are few existing drugs for treating or preventing MC4R-related symptoms, diseases, or conditions, and there is a lack of effective MC4R antagonists for the prevention and treatment of cachexia and anorexia.
Provide MC4R antagonist compound 1 and its pharmaceutically acceptable salt for the preparation of medicines for the treatment or prevention of diseases or symptoms, including oral formulations such as tablets and capsules, with the addition of pharmaceutical excipients, for the treatment or prevention of cachexia, anorexia, etc., by adjusting the proportion of the compound in the medicine and the frequency of administration to achieve therapeutic effects.
It significantly improves chemotherapy-induced weight loss and anorexia symptoms, increases appetite, reduces muscle atrophy and osteoporosis, provides dose-dependent weight gain and improved food intake, and has a good safety profile.
Smart Images
Figure CN122398800A_ABST