Use of ginseng oligosaccharide and composition thereof in preparation of products for preventing, delaying or treating vascular depression

By using Morinda officinalis oligosaccharides and their combinations to regulate neurotransmitters and promote synaptic remodeling, the limitations of existing drugs for treating vascular depression and their significant side effects have been addressed, achieving a safe and effective neuroprotective effect.

CN122398823APending Publication Date: 2026-07-17BEIJING TONGRENTANG CO LTD
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
BEIJING TONGRENTANG CO LTD
Filing Date
2026-03-11
Publication Date
2026-07-17

AI Technical Summary

Technical Problem

Existing medications for treating vascular depression have limited efficacy, significant side effects, high costs, and inconvenience of use. Current physical and psychological treatments cannot fundamentally address the depressive symptoms caused by cerebrovascular lesions and neuronal damage.

Method used

Morinda officinalis oligosaccharides and their combinations are used as novel neuroprotective drugs. Through multi-target mechanisms such as regulating neurotransmitters, protecting mitochondria, inhibiting inflammation, and promoting synaptic remodeling, they are prepared into suitable dosage forms such as oral preparations, injections, and transdermal patches for administration.

Benefits of technology

It significantly improves symptoms of vascular depression, lowers blood pressure, reduces pathological damage to brain tissue, restores neurotransmitter levels, has few side effects, improves patient compliance, and provides continuous and effective treatment.

✦ Generated by Eureka AI based on patent content.

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Abstract

本发明提供巴戟天寡糖及其组合物在制备预防、延缓或治疗血管性抑郁的产品中的应用,涉及医药技术领域。巴戟天寡糖及其组合物在制备预防、延缓或治疗血管性抑郁的产品中的应用,具有多靶点作用、安全性高、成本较低、使用方便等潜在优势,通过动物实验发现巴戟天寡糖对血管性抑郁大鼠具有显著的治疗作用,能改善抑郁样行为,降低血压,减轻脑组织病理损伤,并通过恢复神经递质水平,且副作用小。又进一步开展细胞实验明确了巴戟天寡糖能够促进神经元突触重塑,提高BDNF‑TrkB‑CREB信号通路活性,增强其神经保护效果,为神经元损伤的治疗提供了新的思路,为血管性抑郁的治疗提供新的选择。
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