Use of hippocampus multi-whip pill in preparation of medicine for preventing and treating Alzheimer disease

Hippocampus pills significantly reduce acetylcholinesterase activity by improving motor and cognitive function in AD models. Clinical trials have shown that the effects are similar to those of conventional drugs, providing a new strategy for the treatment of Alzheimer's disease.

CN122398860APending Publication Date: 2026-07-17SHENYANG KANGDA PHARM GRP CO LTD OF SHENYANG
View PDF 0 Cites 0 Cited by

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
SHENYANG KANGDA PHARM GRP CO LTD OF SHENYANG
Filing Date
2026-05-15
Publication Date
2026-07-17

AI Technical Summary

Technical Problem

There is a lack of effective drugs for the prevention and treatment of Alzheimer's disease in the current technology, and existing treatments have failed to effectively control the progression of the disease. Traditional Chinese medicine has unique advantages in this field, and the application of Hippocampus Multi-Bian Pill is a new treatment strategy.

Method used

The application of Hippocampus Multi-Whip Pill in the preparation of drugs for the prevention and treatment of Alzheimer's disease has shown significant improvement in motor ability and cognitive function through experiments on zebrafish and female AD model mice. Clinical trials have shown similar effects to conventional drugs.

Benefits of technology

Hippocampus multi-whip pills significantly improve motor speed and cognitive function in AD models, and reduce acetylcholinesterase activity. Clinical trials have shown certain therapeutic effects, providing a new approach to the treatment of Alzheimer's disease.

✦ Generated by Eureka AI based on patent content.

Smart Images

  • Figure FT_1
    Figure FT_1
  • Figure SMS_1
    Figure SMS_1
  • Figure SMS_2
    Figure SMS_2
Patent Text Reader

Abstract

本发明属于药物新用途技术领域,提供了海马多鞭丸在制备防治阿尔茨海默病药物中的应用。在AD模型斑马鱼的防治功效评价试验中,海马多鞭丸能够明显提高光‑暗刺激条件下的AD模型斑马鱼运动速度。在AD模型雌鼠的防治功效评价试验中,海马多鞭丸在旷场实验中表现出显著缩短中央格的停留时间,以及显著增加站立次数和总行走距离;在Morris水迷宫实验表现出显著缩短逃逸潜伏期,延长雌鼠游泳路程,及提高雌鼠游泳速度;海马多鞭丸能显著降低乙酰胆碱酯酶活性。临床实验也显示出海马多鞭丸对AD患者具有治疗效果。因此,海马多鞭丸具有制备防治阿尔茨海默病药物的应用前景,可为临床上阿尔茨海默病的治疗提供一种新的思路和策略。
Need to check novelty before this filing date? Find Prior Art