Wireless magnetically controlled capsule device for the digestive tract, uses and control method thereof

By designing a wireless magnetically controlled capsule device, the targeted release and activation of photosensitive therapeutic agents at gastrointestinal lesions were achieved, solving the optical penetration and operational challenges of photodynamic therapy in gastrointestinal treatment, and improving treatment efficacy and safety.

CN122399255APending Publication Date: 2026-07-17THE HONG KONG UNIV OF SCI & TECH +1
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
THE HONG KONG UNIV OF SCI & TECH
Filing Date
2026-04-24
Publication Date
2026-07-17

AI Technical Summary

Technical Problem

Existing photodynamic therapy for gastrointestinal treatment suffers from insufficient optical penetration depth, cumbersome operation, and difficulty in reaching curved areas, resulting in poor treatment effects. Furthermore, micron and nanoscale robots have poor stability in acidic and enzymatic environments, making it difficult to achieve precise drug delivery and activation.

Method used

A wireless magnetically controlled capsule device is designed, comprising a drug release component and a light source component. The magnetic control technology enables the directional movement of the capsule in the gastrointestinal tract and the precise activation of the photosensitive therapeutic agent. By utilizing the synergistic effect of the controlled-release layer and the light source component, the directional release and activation of the therapeutic agent at the lesion site is ensured, reducing damage to normal tissues.

Benefits of technology

It improves the targeting and therapeutic effect of photodynamic therapy, enhances the precision and safety of gastrointestinal disease treatment, reduces the risk of damage to normal tissues, and provides a more targeted and safer treatment method.

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Abstract

本发明公开了一种用于消化道的无线磁控胶囊装置、用途及其控制方法,用于消化道的无线磁控胶囊装置包括胶囊本体、驱动组件和光源组件,所述胶囊本体设置有光敏治疗剂;所述驱动组件设置在所述胶囊本体内;所述光源组件设置在所述胶囊本体内,所述光源组件与所述驱动组件连接,所述驱动组件可驱动所述光源组件发出预设光谱范围的光线,以激活所述光敏治疗剂。本发明能够实现药物递送与光激活在时间与空间上的协同,确保光敏治疗剂在病灶部位被定向释放并精确触发,减少光敏治疗剂在非病灶区域被激活而损伤正常胃肠道组织,提高光敏治疗剂在胃肠道光动力灭活中的靶向性与治疗效果,增强光动力治疗的临床应用效果。
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