Electrochemiluminescence immuno-sensor and application thereof in detection of t-2 toxin
By using an urchin-shaped ternary alloy PdCuNi-modified electrode and an electrochemiluminescence immunosensor made of Zr-MOF material, combined with potassium persulfate as a co-reactant, the problems of insufficient sensitivity and difficulty in on-site detection in existing detection methods have been solved, achieving high-sensitivity, rapid and low-cost detection of T-2 toxin.
Patent Information
- Application Number
- CN202610663910.0
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2026-05-14
- Publication Date
- 2026-07-17
AI Technical Summary
Existing methods for detecting T-2 toxin suffer from insufficient sensitivity, susceptibility to matrix interference, and difficulty in achieving rapid on-site detection. In particular, high-performance liquid chromatography (HPLC) is costly and complex to operate, while immunological methods are susceptible to cross-reactivity.
An electrochemiluminescent immunosensor was constructed using a sea urchin-shaped ternary alloy PdCuNi modified electrode and Zr-MOF as the electrochemiluminescent material, combined with potassium persulfate as a co-reactant. Quantitative detection was achieved by binding the electrochemiluminescent probe with the T-2 toxin monoclonal antibody.
It achieves highly sensitive detection of T-2 toxin with low detection limit, fast response speed, simple operation, low cost and easy miniaturization, and its sensitivity is more than 1,000 times higher than that of traditional methods.
Smart Images
Figure CN122409791A_ABST