A time-domain diffuse optical tomography reconstruction method and system

By employing a partitioning strategy and a quasi-Newton method to optimize the model in time-domain diffuse optical tomography, the optical parameters of shallow and deep tissues are reconstructed using logarithmic integral intensity and mean time of flight, respectively. This solves the problems of reconstruction instability and high computational complexity caused by single feature data, and achieves efficient and reliable optical parameter reconstruction.

CN122415799APending Publication Date: 2026-07-17HUAZHONG UNIV OF SCI & TECH
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Patent Information

Application Number
CN202610866432.3
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2026-06-16
Publication Date
2026-07-17

AI Technical Summary

Technical Problem

When using integral transform data for optical reconstruction, time-domain diffuse optical tomography often uses a single feature data type, resulting in poor reliability and stability of the reconstruction, high computational complexity, and difficulty in simultaneously improving spatial computational accuracy and deep spatial sensitivity.

Method used

A partitioning strategy based on spatial sensitivity distribution and depth information is adopted. The optical parameters of shallow and deep tissues are reconstructed by using logarithmic integral intensity and mean flight time, respectively. The quasi-Newton method is combined with the optimization model, and the adjoint method is used to reduce computational complexity and memory usage.

Benefits of technology

It significantly improves the accuracy and stability of optical parameter reconstruction, reduces computational overhead, enhances the reliability and efficiency of reconstruction results, and alleviates the ill-conditioned problem.

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Abstract

本申请属于近红外光谱学和生物医学工程领域,具体公开了一种时域扩散光断层成像重建方法及系统。方法为:构建三维几何模型,使用时域扩散方程描述光在生物组织中的传输过程;采用有限元方法求解该方程并获取三维几何模型表面的时间点扩散函数;根据时间点扩散函数提取特征数据,分别绘制特征数据的空间灵敏度分布图;基于空间灵敏度分布图以及节点深度,选取空间灵敏度高的特征数据作为重建依据;建立逆向问题优化模型,利用相应特征数据,依次完成浅层节点、深层节点的光学参数重建。本申请提升了光学重构的稳定性与可靠性。
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