A fluorouracil decolorization reaction device

Abstract

The utility model relates to a fluorouracil decolorization reaction device, including a reactor and a support platform. A storage tank, a feeding assembly and a buffer box are arranged on the top of the support platform. The feeding assembly includes a feeding tank, a feeding pipe, a support frame, a weight sensor and a vibration motor. A weight sensor is arranged between the bottom of the support frame and the top of the support platform. A feeding tank is arranged on the support frame. A vibration motor is arranged on the top of the feeding tank. A feeding pipe is arranged at the bottom of the feeding tank. A feeding head is arranged at the top of the reactor. The lower end of the feeding pipe extends into the feeding head. A discharge port A is arranged at the bottom of the side of the storage tank for penetrating downward into the feeding tank. A discharge port B is arranged at the bottom of the side of the feeding tank for penetrating downward into the buffer box. A condenser is arranged at the top of the support platform. The lower end inlet of the condenser is connected to a gas pipeline connected to the top of the reactor. An air inlet head is arranged at the bottom of the reactor. A heater is arranged in the reactor. The utility model has the advantages of accurate activated carbon delivery, removal of air retained inside the device, and good product yield.

Description

Technical Field

[0001] The utility model relates to the technical field of chemical production equipment, in particular to a fluorouracil decolorization reaction device. Background Art

[0002] Fluorouracil acts as an anti-metabolite. After being converted into effective fluorouracil deoxynucleotides in cells, it interferes with DNA synthesis by inhibiting thymine nucleotide synthetase. It is often used to treat a variety of tumor diseases.

[0003] The existing fluorouracil decolorization reaction device lacks a precise dosing device for activated carbon. Improper dosing of activated carbon will affect the reaction, and the air retained inside the reaction device will cause fluorouracil to participate in unexpected erroneous reactions, reducing the yield of the final product. It is necessary to remove the air in the reaction device before the decolorization reaction. Utility Model Content

[0004] The utility model aims to provide a fluorouracil decolorization reaction device, which has the advantages of accurate activated carbon addition, capable of removing air retained inside the device and having a good product yield.

[0005] The technical solution of the utility model is as follows:

[0006] A fluorouracil decolorization reaction device comprises a reactor and a support platform, wherein the reactor is below the support platform, and a storage tank, a feeding assembly and a buffer box are arranged on the top of the support platform, and the feeding assembly comprises a feeding tank, a feeding pipe, a support frame, a weight sensor and a vibration motor, and a weight sensor is arranged between the bottom of the support frame and the top of the support platform, a feeding tank is arranged on the support frame, a vibration motor is arranged on the top of the feeding tank, a feeding pipe is arranged at the bottom of the feeding tank, a feeding head is arranged on the top of the reactor, and the lower end of the feeding pipe extends into the feeding head, and the feeding pipe is provided with an electromagnetic valve A at the connection with the feeding tank, and the feeding head is provided with an electromagnetic valve B, and the storage tank is provided with a feeding head. A discharge port A is provided at the bottom of the side of the material tank, a feed port A is provided on the feeding tank for the discharge port A to penetrate downward, and the feed port A does not contact the discharge port A, a discharge port B is provided at the bottom of the side of the feeding tank, a feed port B is provided on the buffer box for the discharge port B to penetrate downward, and the feed port B does not contact the discharge port B, a solenoid valve C is respectively provided on the discharge port A and the discharge port B, a condenser is provided on the top of the support platform, the lower inlet of the condenser is connected to a gas pipeline connected to the top of the reactor, an air inlet head is provided at the bottom of the reactor, and a solenoid valve D is respectively provided on the air inlet head and the upper outlet of the condenser, and a heater is provided in the reactor.

[0007] Preferably, the bottom shape of the storage tank is a slope that slopes downward toward the discharge port A.

[0008] Preferably, a mounting groove is provided on the support platform, and the buffer box is placed in the mounting groove.

[0009] Preferably, a temperature sensor and an air pressure sensor are provided on the top of the reactor, and a display meter is provided on the top of the support platform, and the display meter is connected to the corresponding temperature sensor and air pressure sensor through data lines.

[0010] Preferably, a feed pipe is provided at the top of the reactor, and a discharge pipe is provided at the bottom of the reactor, and a solenoid valve E is provided on each of the feed pipe and the discharge pipe.

[0011] The utility model has the following beneficial technical effects:

[0012] 1. Accurate feeding of activated carbon into the reactor is achieved by using a storage tank, a feeding assembly and a buffer box together; the weight of the activated carbon in the feeding tank is determined by the difference between the initial data value and the current data value of the weight sensor. When feeding, open the solenoid valve C on the discharge port A, and the activated carbon in the storage tank enters the feeding tank. If the activated carbon entering the feeding tank is excessive, open the solenoid valve C on the discharge port B to discharge the excess activated carbon into the buffer box. When the weight of the activated carbon in the feeding tank reaches the required value, open the solenoid valve A, solenoid valve B and the vibration motor, and the activated carbon in the feeding tank enters the reactor through the feeding pipe and the feed head.

[0013] 2. Through the combination of the air inlet head, the gas pipeline and the condenser, the reaction environment inside the reactor is protected by inert gas, and the heated and vaporized materials are helped to condense and return to the reactor, thereby improving the material yield. Before the reaction, the solenoid valve D on the air inlet head and the upper outlet of the condenser is opened, and inert gas is injected into the reactor from the air inlet head. The inert gas squeezes the air inside the reactor from the upper outlet of the condenser into the outside air, so that the inside of the reactor is filled with inert gas to achieve inert gas protection. During the reaction, the inert gas in the reactor expands due to heat, forming a pressure difference with the outside world. When it is necessary to avoid high pressure problems in the reactor, the upper outlet of the condenser is opened, and the excess inert gas flows out. The vaporized material rising with the outflowing gas is cooled and liquefied at the condenser and returned to the reactor, thereby reducing the probability of material loss. BRIEF DESCRIPTION OF THE DRAWINGS

[0014] The technical solution of the utility model will be further described below in conjunction with the accompanying drawings.

[0015] Attached Figure 1 It is the front view of the utility model.

[0016] Attached Figure 2 It is a cross-sectional view from the main perspective of the utility model.

[0017] Attached Figure 3 for Figure 2A magnified view of part A.

[0018] Attached Figure 4 It is a cross-sectional view from the left side of the utility model.

[0019] Attached Figure 5 It is a top view of the utility model.

[0020] In the figure: 1-reactor, 2-support platform, 3-storage tank, 4-feeding assembly, 5-buffer box, 6-feeding tank, 7-feeding pipe, 8-support frame, 9-weight sensor, 10-feeding head, 11-solenoid valve A, 12-solenoid valve B, 13-discharge port A, 14-feeding port A, 15-discharge port B, 16-feeding port B, 17-solenoid valve C, 18-condenser, 19-gas pipeline, 20-gas inlet head, 21-solenoid valve D, 22-heater, 23-installation slot, 24-temperature sensor, 25-air pressure sensor, 26-display meter, 27-data line, 28-feeding pipe, 29-discharge pipe, 30-solenoid valve E, 31-vibration motor. DETAILED DESCRIPTION

[0021] The present invention will be further described in detail below in conjunction with the accompanying drawings and specific embodiments.

[0022] Example:

[0023] like Figures 1 to 5 As shown, this embodiment provides a fluorouracil decolorization reaction device, including a reactor 1 and a support platform 2, the reactor 1 is below the support platform 2, and a storage tank 3, a feeding assembly 4 and a buffer box 5 are arranged on the top of the support platform 2, the feeding assembly 4 includes a feeding tank 6, a feeding pipe 7, a support frame 8, a weight sensor 9 and a vibration motor 31, a weight sensor 9 is arranged between the bottom of the support frame 8 and the top of the support platform 2, a feeding tank 6 is arranged on the support frame 8, a vibration motor 31 is arranged on the top of the feeding tank 6, a feeding pipe 7 is arranged at the bottom of the feeding tank 6, a feeding head 10 is arranged on the top of the reactor 1, and the lower end of the feeding pipe 7 extends into the feeding head 10, and the feeding pipe 7 is provided with an electromagnetic valve A11 at the connection with the feeding tank 6, and the feeding head 10 is provided with an electromagnetic valve B12, and the storage tank 6 is provided with a feeding head 10. A discharge port A13 is provided at the bottom of the side of the tank 3, a feed port A14 is provided on the feeding tank 6 for the discharge port A13 to penetrate downward, and the feed port A14 does not contact the discharge port A13, a discharge port B15 is provided at the bottom of the side of the feeding tank 6, a feed port B16 is provided on the buffer box 5 for the discharge port B15 to penetrate downward, and the feed port B16 does not contact the discharge port B15, a solenoid valve C17 is respectively provided on the discharge port A13 and the discharge port B15, a condenser 18 is provided on the top of the support platform 2, and the lower inlet of the condenser 18 is connected to the gas pipeline 19 connected to the top of the reactor 1, an air inlet head 20 is provided at the bottom of the reactor 1, and the upper outlet of the air inlet head 20 and the condenser 18 are respectively provided with a solenoid valve D21, and a heater 22 is provided in the reactor 1.

[0024] By using the storage tank 3, the feeding assembly 4 and the buffer box 5 in combination, the activated carbon in the reactor 1 can be accurately fed. The weight of the activated carbon in the feeding tank 6 is determined by the difference between the initial data value and the current data value of the weight sensor 9. When feeding, the solenoid valve C17 on the discharge port A13 is opened, and the activated carbon in the storage tank 3 enters the feeding tank 6. If the activated carbon entering the feeding tank 6 is excessive, the solenoid valve C17 on the discharge port B15 is opened to discharge the excess activated carbon into the buffer box 5. When the weight of the activated carbon in the feeding tank 6 reaches the required value, the solenoid valve A11, the solenoid valve B12 and the vibration motor 31 are opened, and the activated carbon in the feeding tank 6 enters the reactor 1 through the feeding pipe 7 and the feed head 10. By using the air inlet head 20, the gas pipeline 19 and the condenser 18 in combination, the reaction environment inside the reactor 1 is protected by inert gas, and the heated and vaporized materials are helped to condense and return to the reactor 1, thereby improving the material yield. Before the reaction, the air inlet head 20 and the solenoid valve D21 on the upper outlet of the condenser 18 are opened, and inert gas is injected into the reactor 1 from the air inlet head 20. The inert gas squeezes the air inside the reactor 1 from the upper outlet of the condenser 18 into the outside air, so that the inside of the reactor 1 is filled with inert gas, thereby realizing inert gas protection. When the reaction is carried out, the inert gas in the reactor 1 expands due to the heat, and forms a pressure difference with the outside. When it is necessary to avoid high pressure problems in the reactor 1, the upper outlet of the condenser 18 is opened, and the excess inert gas flows out. The vaporized materials rising with the outflowing gas are cooled and liquefied at the condenser 18 and returned to the reactor 1, thereby reducing the probability of material loss.

[0025] Furthermore, the bottom of the storage tank 3 is shaped as an inclined surface that slopes downward toward the discharge port A13, so that the activated carbon in the storage tank 3 can slide down along the bottom of the storage tank 3 toward the discharge port A13, so that the activated carbon can enter the feeding tank 6 more smoothly.

[0026] Furthermore, a mounting groove 23 is provided on the support table 2, and the buffer box 5 is placed in the mounting groove 23. The buffer box 5 is placed in the mounting groove 23, firstly, to prevent the buffer box 5 from sliding out of the correct position when in use, and secondly, when pouring the activated carbon accumulated in the buffer box 5 back into the storage tank 3, it is more convenient to take out the buffer box 5 from the mounting groove 23.

[0027] Furthermore, a temperature sensor 24 and an air pressure sensor 25 are provided on the top of the reactor 1, and a display meter 26 is provided on the top of the support platform 2. The display meter 26 is connected to the corresponding temperature sensor 24 and air pressure sensor 25 through a data line 27. The staff can read the data of the corresponding temperature sensor 24 and air pressure sensor 25 through the display meter 26, and can conveniently understand the temperature and air pressure conditions in the reactor 1.

[0028] Furthermore, a feed pipe 28 is provided at the top of the reactor 1, and a discharge pipe 29 is provided at the bottom of the reactor 1. Solenoid valves E30 are provided on the feed pipe 28 and the discharge pipe 29. Liquid materials are added into the reactor 1 through the feed pipe 28, and the mixture containing the product is discharged from the discharge pipe 29 after the reaction is completed.

[0029] The working principle and use process of this utility model:

[0030] Before the reaction, open the solenoid valve D21 on the upper outlet of the air inlet head 20 and the condenser 18, inject inert gas into the reactor 1 from the air inlet head 20 to form an inert gas protection inside the reactor 1, prepare the correct weight of activated carbon in the feeding tank 6, then close the solenoid valve D21 of the air inlet head 20 and open the feeding pipe 28, pour a sufficient amount of a mixture of crude fluorouracil and a corresponding solvent into the reactor 1, start the heater 22 to promote the reaction, the condenser 18 condenses the vaporized material and flows it back to the reactor 1, open the solenoid valve A11 on the feeding pipe 7, the solenoid valve B12 on the feeding head 10 and start the vibration motor 31, let the activated carbon enter the reactor 1, then close the solenoid valve A11, the solenoid valve B12 and the vibration motor 31, the reaction in the reactor 1 continues until the reaction is completed, open the solenoid valve E30 on the discharge pipe 29, and discharge the mixture with the product from the discharge pipe 29.

[0031] The above are only specific application examples of the utility model, and do not constitute any limitation on the protection scope of the utility model. Any technical solution formed by equivalent transformation or equivalent replacement falls within the protection scope of the utility model.

Claims

1. A fluorouracil decolorization reaction device, characterized in that: It includes a reactor and a support platform, wherein the reactor is below the support platform, and a storage tank, a feeding assembly and a buffer box are arranged on the top of the support platform, and the feeding assembly includes a feeding tank, a feeding pipe, a support frame, a weight sensor and a vibration motor, and a weight sensor is arranged between the bottom of the support frame and the top of the support platform, a feeding tank is arranged on the support frame, a vibration motor is arranged on the top of the feeding tank, a feeding pipe is arranged at the bottom of the feeding tank, a feeding head is arranged on the top of the reactor, and the lower end of the feeding pipe extends into the feeding head, and the feeding pipe is provided with an electromagnetic valve A at the connection with the feeding tank, and the feeding head is provided with an electromagnetic valve B, and the bottom of the side of the storage tank A discharge port A is provided, and a feed port A is provided on the feeding tank for the discharge port A to penetrate downward, and the feed port A does not contact the discharge port A. A discharge port B is provided on the bottom of the side of the feeding tank, and a feed port B is provided on the buffer box for the discharge port B to penetrate downward, and the feed port B does not contact the discharge port B. A solenoid valve C is respectively provided on the discharge port A and the discharge port B, a condenser is provided on the top of the support platform, and the lower inlet of the condenser is connected to a gas pipeline connected to the top of the reactor, an air inlet head is provided at the bottom of the reactor, and the air inlet head and the upper outlet of the condenser are respectively provided with a solenoid valve D, and a heater is provided in the reactor.

2. A fluorouracil decolorization reaction device according to claim 1, characterized in that: The bottom of the storage tank is in the shape of an inclined surface that slopes downward toward the discharge port A.

3. A fluorouracil decolorization reaction device according to claim 1, characterized in that: The support platform is provided with a mounting groove, and the buffer box is placed in the mounting groove.

4. A fluorouracil decolorization reaction device according to claim 1, characterized in that: A temperature sensor and an air pressure sensor are arranged on the top of the reactor, and a display meter is arranged on the top of the support platform. The display meter is connected to the corresponding temperature sensor and air pressure sensor through data lines.

5. A fluorouracil decolorization reaction device according to claim 1, characterized in that: A feed pipe is provided on the top of the reactor, and a discharge pipe is provided on the bottom of the reactor. A solenoid valve E is provided on each of the feed pipe and the discharge pipe.

Images