Ophthalmic sustained-release medicine injector

Abstract

The utility model provides an ophthalmic sustained-release medicine injector, which comprises a shell, an ejection button, a needle tube and a pushing mechanism, and is characterized in that the shell forms a handle part of the injector; the ejection button is partially exposed out of the shell and can trigger the pushing mechanism to longitudinally move in the shell, the needle tube is fixed to the head end of the handle part, and slow-release medicine can be contained in the needle tube; when the injector is in a pre-ejection state, the pushing mechanism is stopped at the ejection button; in the ejection state, an operator triggers the ejection button so that the pushing mechanism can longitudinally move in the shell, the bonding force between the sustained-release medicine and the needle tube is overcome, and the sustained-release medicine in the needle tube is smoothly ejected out and delivered into the eye. The injection device is simple in overall structure and convenient to use, the sustained-release medicine implantation process is fast, and the learning curve of an operator is short.

Description

Technical Field

[0001] The present application relates to the technical field of medical devices, and in particular to an ophthalmic sustained-release drug injector. Background Art

[0002] Currently, medication is the most common treatment for ophthalmic diseases. Typically, medications are administered in the form of eye drops, which are applied to the ocular surface. However, compliance with these medications is poor, and the vast majority of eye drops are excreted with tears, resulting in low drug utilization and poor therapeutic efficacy.

[0003] Therefore, with the development of technology, sustained-release drugs have been implanted into the desired part of the eye through delivery devices, such as the anterior chamber, posterior chamber, intraretinal, subretinal, and choroidal spaces. Due to the long-term effect of sustained-release drugs, sustained-release drugs are continuously released after being implanted in the ocular tissue, thereby reducing the frequency of frequent medication for patients. Patients do not need to frequently use eye drops or ointments, thereby improving the convenience of treatment and patient compliance.

[0004] Injectors used to deliver sustained-release drugs into the eye (the drugs referred to here are granular drugs, not liquid drugs) generally adopt slow push injection or catapult delivery. However, the structure and function of existing ophthalmic sustained-release drug injectors still need to be optimized and improved to meet the needs of precise implantation of microparticle sustained-release drugs for intraocular use. Utility Model Content

[0005] In order to solve the above technical problems, the present application provides an ophthalmic sustained-release drug injector, comprising a shell, which forms a handle portion of the injector; an ejection button, wherein the ejection button is partially exposed from the shell, and comprises a pressing portion and a guide portion, and the guide portion has a longitudinal guide channel; a needle tube, wherein the needle tube is fixed to the head end of the handle portion, and the needle tube can accommodate the sustained-release drug; a pushing mechanism, which is arranged in the shell, and comprises: a push rod, an elastic member and a push wire, one end of the push wire is connected to the push rod, and the elastic member acts on the push rod; when the injector is in a pre-ejection state, the push rod stops at the ejection button, and in the ejection state, pressing the pressing portion causes the ejection button to move into the shell, and under the elastic force of the elastic member, the push rod enters the guide channel and drives the push wire to move to eject the sustained-release drug from the needle tube.

[0006] In some embodiments of the present application, a stop portion is provided inside the shell, and the stop portion has a first guide hole; the pressing portion is exposed on the surface of the shell; the guide portion is connected to the pressing portion and is located inside the shell, and one end of the guide portion is adjacent to the stop portion; the guide portion has a second guide hole and a through groove connected to the second guide hole in its longitudinal direction, and the second guide hole and the through groove form the guide channel.

[0007] In some embodiments of the present application, the push rod includes in the axial direction: a first stepped shaft, one end of the first stepped shaft is inserted into the first guide hole; a stop element, one end of the stop element is connected to the other end of the first stepped shaft and can be stopped at the stop portion; a second stepped shaft, one end of the second stepped shaft is connected to the other end of the stop element, and the elastic member acts on the other end of the second stepped shaft.

[0008] In some embodiments of the present application, the pushing mechanism also includes a sliding rod, and the shell also has a fixed part, one end of the sliding rod is fixed to the fixed part, and the other end of the second stepped shaft is provided with a sliding cavity along the axial direction, and the other end of the sliding rod is inserted into the sliding cavity; the elastic part is sleeved on the sliding rod, one end of the elastic part is against the second stepped shaft, and the other end is against the fixed part.

[0009] In some embodiments of the present application, there is at least one limit block in the shell, so that when the ejection button is displaced into the shell, the guide part stops at the limit block; preferably, the ophthalmic sustained-release drug injector also includes a limit pin, which passes through the shell, and when the ophthalmic sustained-release drug injector is in a non-ejection state, the limit pin limits the displacement of the guide part.

[0010] In some embodiments of the present application, the two side surfaces of the guide portion have a first groove; the guide portion also has a first deformable arm arranged in the first groove, the shape of the first deformable arm is adapted to the first groove, a first protrusion is provided on the outer side of the first deformable arm, and a second protrusion is provided on the inner wall of the shell, and the first protrusion can be engaged with the second protrusion.

[0011] In some embodiments of the present application, a reset groove is provided on the shell; the pushing mechanism also includes a reset rod, the fixed end of the reset rod is connected to the push rod, and the free end passes through the reset groove, and the reset rod can move along the reset groove; preferably, a reset hole is provided on the shell at a position corresponding to the bottom of the guide part; or, a reset member with elastic restoring force is also provided between the bottom of the guide part and the limit block.

[0012] In some embodiments of the present application, the head end of the shell has a head end opening; the ophthalmic sustained-release drug injector also includes a head end portion, and the head end portion includes a snap-fit portion and a conical extension portion in the longitudinal direction, and the snap-fit portion is provided with a first snap-fit groove along the outer circumference, and the first snap-fit groove is adapted to the head end opening so that the head end opening of the shell can be snapped into the first snap-fit groove; the conical extension portion extends in a direction away from the snap-fit portion and the cross-sectional size gradually decreases.

[0013] In some embodiments of the present application, engaging holes are provided on two opposite sides of the engaging portion, and a fixing block combined with the engaging holes is provided on the inner wall of the shell.

[0014] In some embodiments of the present application, the ophthalmic sustained-release drug injector further includes a needle sleeve, which is inserted into and fixed in a fixed cavity axially arranged in the conical extension portion, and the proximal end of the needle tube is fixedly connected to the needle sleeve.

[0015] In some embodiments of the present application, the ophthalmic sustained-release drug injector also includes a protective cap, which is pluggable and connected to the head end portion, and the protective cap includes a first covering portion, and second grooves are provided on opposite sides of the first covering portion. The first covering portion also has a second deformable arm provided in the second groove, and the shape of the second deformable arm is adapted to the second groove. A third protrusion is provided on the inner side of the second deformable arm, and the clamping portion is also provided with a second clamping groove along the outer circumference, and the third protrusion can be clamped into the second clamping groove; a second covering portion, the second covering portion extends along the direction of the first covering portion away from the head end portion, and the surface of the second covering portion is provided with an anti-slip protrusion.

[0016] In some embodiments of the present application, a working hole is provided in a radial direction near the distal end of the needle tube; the ophthalmic sustained-release drug injector further comprises a limit plug for being inserted into the working hole to limit the sustained-release drug from falling out of the distal end of the needle tube in an un-ejected state after loading; in the ejection state, the limit plug is removed, and the working hole is used to discharge the air in the needle tube; preferably, the shell comprises a first shell and a second shell that are detachably connected.

[0017] The beneficial effects of the present application are as follows: The present invention provides an ophthalmic sustained-release drug injector, comprising a housing, an ejection button, a needle, and a pushing mechanism, wherein the housing forms the handle portion of the injector; the ejection button is partially exposed from the housing and can trigger the pushing mechanism to move longitudinally within the housing; the needle is fixed to the head end of the handle portion, and the needle can accommodate a sustained-release drug; when the injector is in a pre-ejection state, the pushing mechanism stops at the ejection button; in the ejection state, the operator triggers the ejection button to enable the pushing mechanism to move longitudinally within the housing, overcoming the adhesive force between the sustained-release drug and the needle, smoothly ejecting the sustained-release drug cartridge in the needle and delivering it into the eye. The injector of the present invention has a simple overall structure, is easy to use, and the sustained-release drug implantation process is fast, with a short operator learning curve. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] In order to more clearly illustrate the technical solutions in the embodiments of the application, the following briefly introduces the drawings required for describing the embodiments. Obviously, the drawings described below are only some embodiments of the application. Those skilled in the art can also derive other drawings based on these drawings without inventive work, among which:

[0019] Figure 1A This is a three-dimensional view of an embodiment of the ophthalmic sustained-release drug injection device of the present invention;

[0020] Figure 1B This is a schematic diagram of the internal structure of an embodiment of the ophthalmic sustained-release drug injection device of the present invention;

[0021] Figure 1C This is a schematic diagram of the internal structure of an embodiment of the ophthalmic sustained-release drug injection device of the present invention;

[0022] Figure 1D This is a three-dimensional view of the ejection button of an embodiment of the ophthalmic sustained-release drug injection device of the present invention;

[0023] Figure 1E This is a three-dimensional view of the head end portion of an embodiment of the ophthalmic sustained-release drug injection device of the present invention;

[0024] Figure 1F This is a schematic diagram of a needle tube and a stopper in one embodiment of the ophthalmic sustained-release drug injector of the present invention;

[0025] Figure 1G This is a partial cross-sectional view of an embodiment of the utility model of an ophthalmic sustained-release drug injection device;

[0026] Figure 1H This is a cross-sectional view of an embodiment of the ophthalmic sustained-release drug injection device of the present invention;

[0027] Figure 1IThis is an assembly view of the protective cap of an embodiment of the ophthalmic sustained-release drug injection device of the present invention;

[0028] Figure 1J This is a three-dimensional view of a protective cap in one embodiment of the ophthalmic sustained-release drug injection device of the present invention;

[0029] Figure 1K This is a schematic diagram of the first shell and the second shell in one embodiment of the ophthalmic sustained-release drug injection device of the present invention;

[0030] Figure 2A This is a schematic diagram of the internal structure of another embodiment of the ophthalmic sustained-release drug injection device of the present invention;

[0031] Figure 2B It is a bottom view of another embodiment of the ophthalmic sustained-release drug injection device of the present invention. DETAILED DESCRIPTION

[0032] The following will be combined with the drawings in the embodiments of this application to clearly and completely describe the technical solutions in the embodiments of this application. Obviously, the embodiments described are only part of the embodiments of this application, not all of the embodiments. Based on the embodiments in this application, all other alternative implementations obtained by ordinary technicians in this field without making creative efforts are within the scope of protection of this application.

[0033] like Figures 1A to 2B As shown, the present application provides an ophthalmic sustained-release drug injector 100, which can deliver the sustained-release drug 300 to the required parts in the eye, such as the anterior chamber, posterior chamber, and intraretinal, subretinal, and choroidal spaces. The sustained-release drug 300 is continuously released in the ocular tissue, reducing the frequency of frequent drug administration. Due to the long-lasting effect of the sustained-release drug 300, the patient does not need to frequently use eye drops or apply ointments, thereby improving the convenience of treatment and patient compliance.

[0034] It should be understood that the sustained-release drug 300 in the present application is solid rather than liquid, and is generally in the form of a round or irregular sheet, rod, stick or other shape, which can be accommodated in the needle tube 30 of the ophthalmic sustained-release drug injector 100 for delivery into the eye.

[0035] like Figures 1A to 1KAs shown, as an embodiment of an ophthalmic sustained-release drug injector 100, the ophthalmic sustained-release drug injector 100 includes a shell 10, an ejection button 20, a needle tube 30 and a pushing mechanism 40; wherein, the shell 10 forms the handle portion of the injector to facilitate the operator's grip; the ejection button 20 is partially exposed from the shell 10, and the operator can trigger the ejection button 20 by pressing it to enable the pushing mechanism 40 to move longitudinally within the shell 10, overcome the adhesion force between the sustained-release drug 300 and the needle tube 30, and smoothly eject the sustained-release drug 300 in the needle tube 30 and deliver it to the eye.

[0036] Combine Figure 1A 、 Figure 1B as well as Figure 1K In this embodiment, the shell 10 has a lateral opening 19, which is located at the top of the shell 10. The ejection button 20 is exposed from the shell 10 through the lateral opening 19. The portion of the ejection button 20 exposed from the shell 10 can be a surface or a part of the ejection button 20, so that the operator can easily trigger the ejection button 20.

[0037] like Figure 1D As shown, the ejection button 20 includes a pressing portion 21 and a guide portion 22, wherein the pressing portion 21 is exposed on the surface of the shell 10, and the surface of the pressing portion 21 is provided with a groove for increasing friction, thereby increasing the surface friction of the pressing portion 21, making it convenient for the operator to press and preventing slippage.

[0038] The guide portion 22 is connected to the pressing portion 21 and is located inside the housing 10. Figure 1C The housing 10 is provided with a stopper 11, one end of the guide portion 22 is adjacent to the stopper 11, and the stopper 11 has a first guide hole 111; the guide portion 22 has a guide channel 221 in its length direction (i.e., longitudinal direction), and the guide channel 221 includes a second guide hole 222 and a through groove 223 connected to the second guide hole 222, and the two together form the guide channel 221. Figure 1B and Figure 1C As shown, when the ejection button 20 is not triggered, the first guide hole 111 and the second guide hole 222 in the shell 10 are misaligned up and down, and the pushing mechanism 40 is stopped at the guide portion 22 and cannot move longitudinally in the shell 10 through the guide channel 221; after the ejection button 20 is triggered, the first guide hole 111 and the second guide hole 222 in the shell 10 are coaxial, and the pushing mechanism 40 can move longitudinally in the shell 10 through the guide channel 221, thereby ejecting the sustained-release drug 300 from the needle tube 30.

[0039] like Figure 1BAs shown, in this embodiment, there is at least one limit block 13 in the shell 10. The limit block 13 is arranged on the side of the inner wall of the shell 10 opposite to the ejection button 20, so that when the ejection button 20 is displaced into the shell 10 (its displacement direction is perpendicular to the longitudinal direction), the guide portion 22 in the ejection button 20 stops at the limit block 13, thereby limiting further displacement of the ejection button 20.

[0040] For example Figure 1D As shown, in some embodiments, in order to make the ejection button 20 have a comfortable pressing feel, the ejection button 20 is a hollow structure as a whole, and the second guide hole 222 and the through groove 223 are connected to the internal cavity of the ejection button. At this time, a first slot 224 and a first deformable arm 225 are provided on both sides of the guide portion 22. The first slot 224 is connected to the internal cavity of the guide portion 22, and the first deformable arm 225 is provided in the first slot 224. The shape of the first deformable arm 225 is adapted to the first slot 224. The outer side of the first deformable arm 225 is provided with a first protrusion 226 protruding outward. Accordingly, as shown in FIG. Figure 1H and 1K As shown, a second protrusion 14 is provided at a corresponding position on the inner wall of the shell 10; when the ejection button 20 is not triggered, the first protrusion 226 is engaged with the second protrusion 14, that is, the second protrusion 14 will hinder the ejection button 20 from moving into the shell 10; when the ejection button 20 is triggered, it moves toward the shell 10, and the first protrusion 226 is squeezed by the second protrusion 14 so that the first deformation arm 225 is deformed toward the guide portion 22. At this time, the first protrusion 226 releases the restriction of the second protrusion 14 and follows the displacement of the guide portion 22.

[0041] Furthermore, in order to make the first deformable arm 225 more easily deformable and avoid excessive force causing the ejection button 20 to move, the first deformable arm 225 is also provided with a pressure reducing hole 227. The pressure reducing hole 227 is close to the connection between the first deformable arm 225 and the first slot 224, reducing the combined length of the first deformable arm 225 and the first slot 224, making the first deformable arm 225 more easily deformable, thereby reducing the force required for the operator to trigger the ejection button 20.

[0042] like Figure 1B 、 Figure 1C as well as Figure 1KAs shown, the ophthalmic sustained-release drug injector 100 further includes a limit pin 50, which passes through the shell 10. The shell 10 is provided with a pin hole 104 for the limit pin 50 to pass through. When the ophthalmic sustained-release drug injector 100 is in the ejection state, the limit pin 50 is located at the bottom of the guide portion 22 and can limit the displacement of the guide portion 22; that is, the limit pin 50 is provided to prevent the ophthalmic sustained-release drug injector 100 from being accidentally triggered. When in use, the ejection button 20 can be triggered only after the limit pin 50 is pulled out, thereby enhancing the safety of the ophthalmic sustained-release drug injector 100 during transportation or use.

[0043] In this embodiment, the pushing mechanism 40 is arranged in the shell 10, and the pushing mechanism 40 includes a push rod 41, an elastic member 42 and a push wire 43. One end of the push wire 43 is connected to the push rod 41, and the elastic member 42 acts on the push rod 41; when the injector is in the pre-ejection state, the push rod 41 stops at the ejection button 20. In the ejection state, pressing the pressing portion 21 causes the ejection button 20 to move into the shell 10. Under the elastic force of the elastic member 42, the push rod 41 enters the guide channel 221 and drives the push wire 43 to move along the axial direction of the needle tube to eject the sustained-release drug 300 from the needle tube 30.

[0044] like Figure 1C As shown, the push rod 41 includes a first stepped shaft 411, a stop element 412 and a second stepped shaft 413 in the axial direction, wherein one end of the first stepped shaft 411 is inserted into the first guide hole 111; one end of the stop element 412 is connected to the other end of the first stepped shaft 411, and its cross-sectional dimension is larger than the cross-sectional dimension of the first guide hole 111, and can be stopped at the first guide hole 111 of the stop part 11; one end of the second stepped shaft 413 is connected to the other end of the stop element 412, and the elastic member 42 acts on the other end of the second stepped shaft 413. When the pusher is in the pre-ejection state, the elastic member 42 is in a compressed state, and the first stepped shaft 411 stops at the guide portion 22 of the ejection button 20; in the ejection state, the elastic member 42 releases the elastic force, acting on the second stepped shaft 413 to make the first stepped shaft 411 enter the second guide hole 222, thereby pushing the push wire 43 to move axially along the needle tube 30 and push the sustained-release drug 300. When the stopping element 412 stops at the first guide hole 111, the first stepped shaft 411 stops moving, the sustained-release drug 300 pops out of the needle tube 30, and the pusher completes the ejection.

[0045] In order to improve the stability of the longitudinal movement of the first stepped shaft 411, the pushing mechanism 40 also includes a sliding rod 44. The housing 10 has a fixed portion 12, one end of the sliding rod 44 is fixed to the fixed portion 12, and the other end of the second stepped shaft 413 is provided with an axial sliding cavity 4131 along the axial direction. The other end of the sliding rod 44 is inserted into the axial sliding cavity 4131. The sliding rod 44 can provide a guide for the second stepped shaft 413 to prevent the second stepped shaft 413 from generating radial displacement during movement; the elastic member 42 is sleeved on the sliding rod 44, one end of the elastic member 42 is against the second stepped shaft 413, and the other end is against the fixed portion 12. When the injector is in the pre-ejection state, the second stepped shaft 413 squeezes the elastic member 42, so that the elastic member 42 is compressed to provide thrust to the second stepped shaft 413 in the ejection state.

[0046] like Figure 1C As shown, preferably, there are multiple fixing parts 12, each of which has a fixing hole 121. One end of the sliding rod 44 passes through the fixing holes 121 of the multiple fixing parts 12 and is fixedly connected to the multiple fixing parts 12, thereby enhancing the end stability of the sliding rod 44. The elastic member 42 is located between the second stepped shaft 413 and the fixing part 12 adjacent to the second stepped shaft 413.

[0047] In some other embodiments, in order to enhance the protection of the push wire 43 and prevent the push wire 43 from bending during movement, the pushing mechanism 40 also includes a push wire sleeve (not shown), the inner diameter of the push wire sleeve is slightly larger than the outer diameter of the push wire 43, to ensure that the push wire can move smoothly in the push wire sleeve, the push wire sleeve is fixedly connected to the first stepped shaft 411, and the other end extends in the axial direction of the push wire 43, or one end of the push sleeve is slidably connected to the first stepped shaft 411, and the other end is fixed in the head end 60 of the injector 100.

[0048] In some other embodiments, the pushing mechanism 40 does not have the slide bar 44, and the elastic member 42 is disposed between the second stepped shaft 413 and the fixed portion 12. One end of the elastic member 42 is fixedly connected to the second stepped shaft 413, and the other end of the elastic member 42 is connected to the fixed portion 12. After being compressed, the elastic member 42 provides elastic force to the second stepped shaft 413.

[0049] In this embodiment, the head end of the housing 10 has a head end opening 18, and the ophthalmic sustained-release drug injector 100 further includes a head end portion 60 fixed to the head end opening 18. Figure 1E As shown, the head portion 60 includes a snap-fit portion 61 and a tapered extension 62 in the longitudinal direction. The snap-fit portion 61 is provided with a first snap-fit groove 611 along its outer circumference. The first snap-fit groove 611 mates with the head opening 18, allowing the head opening 18 of the housing 10 to snap into the first snap-fit groove 611. In other embodiments, the head portion 60 is integrally formed with the housing 10, reducing the number of parts in the injector, lowering assembly difficulty, and reducing processing requirements.

[0050] Furthermore, in this embodiment, two opposite sides of the engaging portion 61 are provided with engaging holes 613, such as Figure 1K As shown, the inner wall of the shell 10 is provided with a fixing block 15 combined with the snap-fit hole 613. When the head end 60 is installed, the fixing block 15 in the shell 10 can be inserted into the snap-fit hole 613 to further strengthen the fixed connection between the shell 10 and the head end 60 and prevent the head end 60 from detaching from the shell 10.

[0051] The tapered extension portion 62 has a conical cylindrical structure, extending in a direction away from the engaging portion 61 and gradually decreasing in cross-sectional size. The tapered extension portion 62 is axially provided with a fixed cavity. The ophthalmic sustained-release drug injector 100 further includes a needle sleeve 90, which is inserted into and fixed in the fixed cavity. The proximal end of the needle tube 30 is fixedly connected to the needle sleeve 90, and the distal end of the needle tube 30 extends in a direction away from the housing 10. The needle tube 30 can accommodate a sustained-release drug 300.

[0052] like Figure 1I and Figure 1J As shown, in order to enhance the protection of the needle tube 30, the ophthalmic sustained-release drug injector 100 further includes a protective cap 70, which is pluggable and connected to the head end portion 60. The protective cap 70 includes a first covering portion 71 and a second covering portion 72 in the longitudinal direction, wherein the first covering portion 71 is provided with a second slot 711 on opposite sides thereof. The first covering portion 71 further includes a second deformable arm 712 disposed in the second slot 711. The shape of the second deformable arm 712 is adapted to the second slot 711. The inner side of the second deformable arm 712 (i.e., the inner wall of the protective cap 70) is provided with a third protrusion 713. Figure 1E In the embodiment, the engaging portion 61 is further provided with a second engaging groove 612 along the outer circumference thereof, and the third protrusion 713 can be engaged in the second engaging groove 612 .

[0053] When the protective cap 70 is inserted and connected with the head end portion 60 along the longitudinal direction, the front end of the locking portion 61 squeezes the third protrusion 713 to deform the second deformation arm 712, causing the second deformation arm 712 to expand outward, and the protective cap 70 can further move longitudinally toward the shell 10, and finally the third protrusion 713 is engaged with the second locking groove 612, completing the insertion connection with the head end portion 60; similarly, when the injector is in use, the second deformation arm 712 is deformed when the protective cap 70 is pulled out of the head end portion 60, and the protective cap 70 is easily separated from the head end portion 60.

[0054] The second covering portion 72 extends along the direction of the first covering portion 71 away from the head end portion 60 to adapt to the length of the needle tube 30. The surface of the second covering portion 72 is provided with an anti-slip protrusion 721 to enhance the surface friction of the second covering portion 72 and facilitate the operator to insert and remove the protective cap 70.

[0055] like Figure 1Fand Figure 1G As shown, in this embodiment, a working hole 31 is provided in the radial direction at a position near the distal end of the needle tube 30; the ophthalmic sustained-release drug injector 100 further includes a limit plug 80 for being inserted into the working hole 31 to limit the sustained-release drug 300 from falling out of the distal end of the needle tube 30 after loading and not ejected, that is, before the ophthalmic sustained-release drug injector 100 is used, the sustained-release drug 300 is loaded in the needle tube 30, and the limit plug 80 can serve as a stopper for the sustained-release drug 300 to prevent the sustained-release drug 300 from falling out of the distal end of the needle tube 30; when the ophthalmic sustained-release drug injector 100 is in the ejection state, the limit plug 80 needs to be removed, and the sustained-release drug 300 can be ejected from the needle tube 30 under the push of the push wire 43, and during the ejection process of the sustained-release drug 300, the working hole 31 can discharge the air in the needle tube 30, thereby reducing the air from entering the eye during the implantation process.

[0056] like Figure 1K As shown, in this embodiment, the shell 10 includes a first shell 16 and a second shell 17 that are detachably connected; positioning columns 102 are provided on the inner walls of the first shell 16 and the second shell 17, one of the positioning columns 102 is provided with a positioning groove, and the other positioning column 102 is provided with a positioning protrusion, which can be inserted and fixed in the positioning groove to achieve the connection between the first shell 16 and the second shell 17; anti-slip grooves 105 are also provided on the outer walls of the first shell 16 and the second shell 17, and the anti-slip grooves 105 are adjacent to the ejection button 20 to enhance the friction of the operator holding the handle.

[0057] In addition, the shell 10 in this embodiment is divided into a first shell 16 and a second shell 17 located on the left and right sides along the vertical direction. The stop portion 11, the first guide hole 111, the limit block 13, the head end opening 18 and the side opening 19 in this embodiment are all divided into two symmetrical parts.

[0058] As can be seen, the ophthalmic sustained-release drug pusher 100 in this embodiment adopts a one-button structure, which enables the push mechanism 40 to move longitudinally within the housing 10, and overcomes the adhesion between the sustained-release drug 300 and the needle tube 30 by axially moving the push wire 43 in the needle tube 30, thereby smoothly ejecting the sustained-release drug 300 in the needle tube 30 and delivering it into the eye; the overall structure of the pusher is simple, easy to use, the sustained-release drug 300 is implanted quickly, and the operator has a short learning curve; and the distal end of the needle tube 30 has a working hole 31, which cooperates with the limit plug 80 to place the sustained-release drug 300 in the needle tube 30. During the ejection process of the sustained-release drug 300, the working hole 31 can expel the air in the needle tube 30, reducing the amount of air entering the eye during the implantation process. The ophthalmic sustained-release drug pusher 100 in this embodiment is a disposable medical device, that is, the ophthalmic sustained-release drug pusher 100 is no longer used after ejecting the sustained-release drug 300, which can avoid cross infection and reduce the workload of cleaning and disinfection.

[0059] But in another embodiment of the present application, Figure 2A and Figure 2B As shown, different from the above Figures 1A to 1K In the illustrated embodiment, the housing 10 is provided with a reset slot 101, and the pushing mechanism 40 further includes a reset lever 45. The fixed end of the reset lever 45 is connected to the push rod 41, and the free end extends through the reset slot 101, allowing the reset lever 45 to move along the reset slot 101. A reset hole 103 is provided in the housing 10 at a position corresponding to the bottom of the guide portion 22. In this embodiment, after the pusher completes a single ejection, the reset lever 45 can push the push rod 41 back to its initial position. A pin can then be inserted through the reset slot 103 to abut the guide portion 22, causing the guide portion 22 to return to its initial position and exposing the pressing portion 21 from the housing 10. This allows the pusher to be used multiple times, making it particularly suitable for proofing or testing scenarios.

[0060] Furthermore, in some other embodiments, a reset member with elastic restoring force is provided between the bottom of the guide portion 22 and the limit block 13. After the ejector completes an ejection, the push rod 41 can be pushed back to the initial position through the reset rod 45, and the ejection button 20 automatically returns to its original position under the elastic force of the reset member, thereby meeting the requirements of repeated use.

[0061] Finally, it should be noted that if the embodiments of the present application involve directional indications (such as up, down, left, right, front, back...), such directional indications are only used to explain the relative position relationship, movement status, etc. between the various components under a certain specific posture (as shown in the accompanying drawings). If the specific posture changes, the directional indication will also change accordingly.

[0062] In addition, if there are descriptions involving "first", "second", etc. in the embodiments of the present application, the descriptions of "first", "second", etc. are only for descriptive purposes and cannot be understood as indicating or implying their relative importance or implicitly indicating the number of the indicated technical features. Therefore, the features defined as "first" and "second" may explicitly or implicitly include at least one of such features. In addition, the technical solutions between the various embodiments can be combined with each other, but they must be based on the fact that they can be implemented by ordinary technicians in this field. When the combination of technical solutions is contradictory or cannot be implemented, it should be deemed that such a combination of technical solutions does not exist and is not within the scope of protection required by this application.

[0063] The above is only an implementation method of the present application and does not limit the patent scope of the present application. Any equivalent structure or equivalent process transformation made using the contents of the description and drawings of this application, or directly or indirectly applied in other related technical fields, are also included in the patent protection scope of the present application.

Claims

1. An ophthalmic sustained-release drug injection device, characterized in that: include: a housing forming a handle portion of the injector; An ejection button, the ejection button portion being exposed outside the housing and comprising a pressing portion and a guide portion, the guide portion having a longitudinal guide channel; a needle tube, the needle tube being fixed to the head end of the handle portion, and the sustained-release drug being accommodated in the needle tube; A pushing mechanism is provided in the housing and comprises: a push rod, an elastic member and a push wire, wherein one end of the push wire is connected to the push rod, and the elastic member acts on the push rod; When the injector is in a pre-ejection state, the push rod stops at the ejection button. In the ejection state, pressing the pressing portion causes the ejection button to move into the shell. Under the elastic force of the elastic member, the push rod enters the guide channel and drives the push wire to move to eject the sustained-release drug from the needle tube.

2. The ophthalmic sustained-release drug injector according to claim 1, characterized in that: A stopper is provided inside the housing, and the stopper has a first guide hole; The pressing portion is exposed on the surface of the shell; the guide portion is connected to the pressing portion and is located inside the shell, and one end of the guide portion is adjacent to the stop portion; the guide portion has a second guide hole and a through groove connected to the second guide hole in its longitudinal direction, and the second guide hole and the through groove form the guide channel.

3. The ophthalmic sustained-release drug injector according to claim 2, characterized in that: The push rod includes, in the axial direction: a first stepped shaft, one end of which is inserted into the first guide hole; a stopper element, one end of which is connected to the other end of the first stepped shaft and is capable of being stopped by the stopper portion; A second stepped shaft, one end of the second stepped shaft is connected to the other end of the stop element, and the elastic member acts on the other end of the second stepped shaft.

4. The ophthalmic sustained-release drug injector according to claim 3, characterized in that: The pushing mechanism also includes a sliding rod, and the shell also has a fixed part. One end of the sliding rod is fixed to the fixed part, and the other end of the second stepped shaft is provided with a sliding cavity along the axial direction, and the other end of the sliding rod is inserted into the sliding cavity; the elastic member is sleeved on the sliding rod, and one end of the elastic member is against the second stepped shaft, and the other end is against the fixed part.

5. The ophthalmic sustained-release drug injector according to claim 2, characterized in that: At least one limit block is provided in the shell, so that when the ejection button moves into the shell, the guide portion stops at the limit block.

6. The ophthalmic sustained-release drug injector according to claim 1, characterized in that: The ophthalmic sustained-release drug injector further includes a limiting pin, which passes through the housing. When the ophthalmic sustained-release drug injector is in a non-ejection state, the limiting pin limits the displacement of the guide portion.

7. The ophthalmic sustained-release drug injector according to claim 5, characterized in that: The two side surfaces of the guide portion have a first groove; the guide portion also has a first deformable arm arranged in the first groove, the shape of the first deformable arm is adapted to the first groove, a first protrusion is provided on the outer side of the first deformable arm, and a second protrusion is provided on the inner wall of the shell, and the first protrusion can be engaged with the second protrusion.

8. The ophthalmic sustained-release drug injector according to claim 6, characterized in that: The housing is provided with a reset chute; the pushing mechanism further comprises a reset rod, the fixed end of the reset rod is connected to the push rod, the free end passes through the reset chute, and the reset rod can move along the reset chute.

9. The ophthalmic sustained-release drug injector according to claim 5, characterized in that: A reset hole is provided on the housing at a position corresponding to the bottom of the guide portion; or a reset member with elastic restoring force is provided between the bottom of the guide portion and the limit block.

10. The ophthalmic sustained-release drug injector according to claim 1, characterized in that: The head end of the shell has a head end opening; The ophthalmic sustained-release drug injector also includes a head end portion, which includes a snap-fit portion and a tapered extension portion in the longitudinal direction. The snap-fit portion is provided with a first slot along the outer circumference, and the first slot is adapted to the head end opening so that the head end opening of the shell can be snapped into the first slot; the tapered extension portion extends in a direction away from the snap-fit portion and its cross-sectional size gradually decreases.

11. The ophthalmic sustained-release drug injector according to claim 10, characterized in that: The two opposite sides of the clamping portion are provided with clamping holes, and the inner wall of the shell is provided with a fixing block combined with the clamping holes.

12. The ophthalmic sustained-release drug injector according to claim 10, characterized in that: The ophthalmic sustained-release drug injector further comprises a needle sleeve, which is inserted into and fixed in a fixed cavity axially arranged in the conical extension portion, and the proximal end of the needle tube is fixedly connected to the needle sleeve.

13. The ophthalmic sustained-release drug injector according to claim 10, characterized in that: The ophthalmic sustained-release drug injector further includes a protective cap, which is pluggably connected to the head end, and the protective cap includes: a first covering portion, wherein second slots are provided on opposite sides of the first covering portion, the first covering portion further comprising a second deformable arm disposed in the second slot, the shape of the second deformable arm being adapted to the second slot, a third protrusion being provided on the inner side of the second deformable arm, the engaging portion further comprising a second slot along the outer circumference thereof, the third protrusion being engageable with the second slot; The second covering portion extends in a direction away from the head end portion along the first covering portion, and a surface of the second covering portion is provided with anti-slip protrusions.

14. The ophthalmic sustained-release drug injector according to any one of claims 1 to 13, characterized in that: The needle tube is provided with a working hole in the radial direction near the distal end thereof; The ophthalmic sustained-release drug injector also includes a limit plug for inserting into the working hole to limit the sustained-release drug from falling out of the distal end of the needle tube in the un-ejected state after loading. In the ejection state, the limit plug is removed and the working hole is used to discharge the air in the needle tube.

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