Anesthesia box for experimental animals

By introducing an automated airtight component structure and sliding auxiliary mechanism into the anesthesia box, the complex problem of gas access in the existing anesthesia box is solved, the anesthesia efficiency and sealing are improved, and the fixing accuracy of animals is ensured through fixed piles and positioning lines, reducing operational errors in radiation therapy.

CN223275546UActive Publication Date: 2025-08-29XIN HUA HOSPITAL AFFILIATED TO SHANGHAI JIAO TONG UNIV SCHOOL OF MEDICINE
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Patent Information

Application Number
CN202422176614.7
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-09-05
Publication Date
2025-08-29
Estimated Expiration
2034-09-05

AI Technical Summary

Technical Problem

The existing anesthesia box has complex gas access and termination operations in radiation therapy, which affects the efficiency of anesthesia and increases the error of manual radiotherapy.

Method used

An anesthesia box is designed, adopting the structure of the first and second airtight parts, and automatically opening the connecting channel through hardware or fluid top opening, combining sliding auxiliary mechanisms and locking parts to ensure the sealing effect, and fixing piles and positioning lines are provided in the box to assist in the fixing and positioning of the animal.

Benefits of technology

The gas access process is simplified, the anesthesia efficiency is improved, the manual operation time is reduced, the sealing of the connection channel and the fixing accuracy of the animals is ensured, and the risk of operational errors in radiation therapy is reduced.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model relates to the technical field of animal anesthesia, in particular to an anesthesia box which comprises a box body, a connector arranged on the box body and a connecting pipeline, and the connecting pipeline can be inserted into the connector to form a connecting channel. A first airtight piece and a second airtight piece are arranged in the connecting channel; the first airtight piece can be jacked open when the connecting pipeline is inserted into the connector, the second airtight piece can be jacked open by fluid from the connecting pipeline, and the connecting channel is unblocked. The first airtight piece and the second airtight piece are jacked open by hardware or fluid respectively, so that the connecting channel is opened and unobstructed, opening of the airtight pieces and unobstructed connecting channel are completed in the process that the connecting pipeline is connected into the connector, manual adjustment or calibration is omitted, and anesthesia efficiency is improved.
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Description

Technical Field

[0001] This patent relates to the field of animal anesthesia technology, and in particular to an anesthesia box for experimental animals suitable for radiotherapy. Background Art

[0002] Radiotherapy, a medical procedure that uses high-energy radiation to treat malignant tumors, plays a crucial role in cancer treatment. According to statistics, approximately 70% of cancer patients require radiotherapy during their treatment, and approximately 40% of cancers can be cured with radiotherapy. Animal experiments play a crucial role in the research and clinical application of radiotherapy. These experiments help explore the principles of radiotherapy, such as observing its cell-killing effects and understanding how it disrupts the DNA structure of tumor cells.

[0003] Currently, animal anesthesia techniques are widely used in radiotherapy research. The main anesthesia methods include injectable anesthesia and gas anesthesia. Gas anesthesia has become the most popular and mainstream anesthesia method due to its safety and easy control of depth. To meet clinical and research needs, a variety of commercial gas chambers have emerged on the market and are widely used in medical research.

[0004] However, in actual radiotherapy, the gas connection and termination operations of the anesthesia box in the prior art are complicated, which affects the anesthesia efficiency and increases the manual operation errors of radiotherapy. Utility Model Content

[0005] In order to solve or at least partially solve the above technical problems, this patent provides an anesthesia box, which is characterized by comprising:

[0006] The box and the interface provided on the box, and

[0007] A connecting pipe, which can be plugged into the interface to form a connecting channel;

[0008] A first airtight member and a second airtight member are provided in the connecting passage;

[0009] The first air-sealing member can be pushed open when the connecting pipe is plugged into the interface, and the second air-sealing member can be pushed open by the fluid from the connecting pipe to make the connecting channel unobstructed.

[0010] Optionally, in the anesthesia box as described above,

[0011] The first airtight member is disposed in the connecting pipe, and the interface pushes the first airtight member open, so that the fluid can enter the interface and push the second airtight member open; or

[0012] The first airtight member is arranged on the interface. After the connecting pipe pushes the first airtight member open, the fluid pushes the second airtight member open and enters the interface.

[0013] Optionally, in the anesthesia box as described above,

[0014] The second airtight member comprises:

[0015] An airtight ring, arranged on the inner wall of the connecting channel;

[0016] At least three flexible valves are arranged on the airtight ring. In a natural state, the at least three flexible valves are closed and form a seal for the connecting channel together with the airtight ring.

[0017] Optionally, in the aforementioned anesthesia box, the number of the flexible valves of the second airtight member is 4-8.

[0018] Optionally, in the anesthesia box as described above, the structure of the first airtight member is consistent with the structure of the second airtight member.

[0019] Optionally, in the anesthesia box as described above, the first airtight member comprises:

[0020] The disposable film is arranged on the inner wall of the connecting pipe. The interface punctures the disposable film so that the fluid can enter the interface and push the second airtight component open.

[0021] Optionally, the anesthesia box as described above further comprises:

[0022] Loading plate, comprising:

[0023] Bottom plate, used for placing the box;

[0024] The side plate is provided with a through hole at a position corresponding to the interface, and the through hole is used to pass the connecting pipe.

[0025] Optionally, in the anesthesia box as described above, the carrying plate further comprises:

[0026] The sliding auxiliary mechanism is provided on the bearing plate so that when the box body is placed on the bottom plate, it can move in the direction close to the side plate to connect the interface with the connecting pipe;

[0027] The sliding auxiliary mechanism is a slope arranged on the side of the bottom plate away from the side plate, and / or the sliding auxiliary mechanism is a slide rail arranged on the bottom plate along a direction close to or away from the side plate.

[0028] Optionally, in the anesthesia box as described above, a first locking member is provided on the side panel, and the box body further comprises:

[0029] A box cover and a second locking member provided on the box cover;

[0030] The first locking member and the second locking member cooperate with each other to lock the box cover in a closed state.

[0031] Optionally, in the anesthesia box as described above, the carrying plate further comprises:

[0032] Positioning slots are arranged in pairs on both sides of the bottom plate;

[0033] The positioning slot can limit the direction in which the box approaches the side panel so that the interface moves toward the connecting channel;

[0034] The positioning slot is a clamping plate, and the contact surface between the clamping plate and the box body is parallel to the axis of the connecting channel.

[0035] Optionally, in the anesthesia box as described above, a plurality of fixing piles are provided in the box body, and the fixing piles are used to fix the experimental animals;

[0036] Positioning lines are marked inside the box to assist in positioning the experimental animals.

[0037] Compared with the existing technology, this patent has the following technical effects:

[0038] During the process of connecting the pipe access interface, the first airtight member and the second airtight member are pushed open by hardware or fluid to open and unobstructed the connection channel. During the process of connecting the pipe access interface, the airtight member is opened and the connection channel is unobstructed, eliminating the need for manual adjustment or calibration. In addition, the connection method is simple, efficient and convenient, shortening the process links and saving time for the entire anesthesia process, thereby improving anesthesia efficiency. In addition, the double seal of the first airtight member and the second airtight member can ensure a good sealing effect for the connection channel. In addition, the sliding auxiliary mechanism on the supporting plate provides a stable and accurate access path for the docking of the interface on the box body and the connection channel, which can assist in completing the docking. The locking members on the box body and the box cover cooperate with each other to keep the box cover closed under anesthesia, thereby preventing gas leakage caused by operational errors during the radiotherapy process. BRIEF DESCRIPTION OF THE DRAWINGS

[0039] To more clearly illustrate the embodiments of this patent, the following briefly introduces the relevant drawings. It is understood that the drawings described below are only used to illustrate some embodiments of this patent, and those skilled in the art can also obtain many other technical features and connection relationships not mentioned herein based on these drawings.

[0040] Figure 1 It is a three-dimensional schematic diagram of an anesthesia box according to an embodiment of the present patent;

[0041] Figure 2 It is a cross-sectional schematic diagram of an anesthesia box according to an embodiment of the present patent;

[0042] Figure 3This is a three-dimensional schematic diagram of an anesthesia box from another angle according to an embodiment of the present invention;

[0043] Figure 4 This is a three-dimensional schematic diagram of the connection channel of an anesthesia box in the embodiment of the present patent;

[0044] Figure 5 This is a three-dimensional schematic diagram of a box placed in a radiotherapy device according to an embodiment of this patent.

[0045] Description of reference numerals:

[0046] A. Anesthesia box; B. Radiotherapy equipment;

[0047] 1. Box body; 11. Interface; 12. Box cover; 121. Second locking member;

[0048] 2. Connect the pipes;

[0049] 3. First airtight part;

[0050] 4. Second airtight member; 41. Airtight ring; 42. Flexible valve;

[0051] 5. Carrying plate; 51. Bottom plate; 52. Side plate; 521. First locking member; 53. Sliding auxiliary mechanism; 531. Slope; 54. Positioning slot;

[0052] 6. Fixed piles;

[0053] 7. Interlocking buckle;

[0054] 8. Air outlet. DETAILED DESCRIPTION

[0055] The following is a detailed description of this patent in conjunction with the accompanying drawings.

[0056] Implementation Method 1

[0057] The anesthesia box in the prior art generally requires manual access and sealing of the anesthesia gas pipeline to the anesthesia box, which is complicated and time-consuming. Figure 1 and Figure 2 Shown, including:

[0058] The box body 1 and the interface 11 provided on the box body 1, and

[0059] The connecting pipe 2 can be plugged into the interface 11 to form a connecting channel;

[0060] A first airtight member 3 and a second airtight member 4 are provided in the connecting passage;

[0061] The first airtight member 3 can be pushed open when the connecting pipe 2 is plugged into the interface 11 , and the second airtight member 4 can be pushed open by the fluid from the connecting pipe 2 to make the connecting channel unobstructed.

[0062] The housing 1 is provided with an interface 11, and the connecting pipe 2 can be plugged into the interface 11 of the housing 1 to form a connecting channel, and the fluid can enter the housing 1 through the connecting channel. A first airtight part 3 and a second airtight part 4 are provided in the connecting channel, and the first airtight part 3 and the second airtight part 4 can seal the fluid in the connecting channel. For example, the first airtight part 3 can be provided in the interface 11, and the second airtight part 4 can be provided in the connecting pipe 2. Then, the process of the fluid flowing into the anesthesia box A is as follows: when the connecting pipe 2 is connected to the interface 11, the first airtight part 3 in the interface 11 can first be pushed open during the process of inserting the connecting pipe 2 into the interface 11, and then, the second airtight part 4 can be pushed open by the fluid in the pipe after the first airtight part 3 is pushed open, and the fluid then enters the interior of the anesthesia box A through the second airtight part 4 and the first airtight part 3 in the connecting channel.

[0063] In the prior art, the inlet and outlet of the box body 1 and the sealing buckle are mostly made of metal, which will seriously affect the energy of the radiation during radiotherapy and thus affect the treatment effect. The anesthesia box A provided by this patent can be made of polymer materials as a whole, which can avoid this problem.

[0064] Compared with the prior art, the above-mentioned anesthesia box A has the following technical effects:

[0065] 1. During the process of connecting the connecting pipe 2 to the interface 11, the first airtight member 3 and the second airtight member 4 are pushed open by hardware or fluid to open and unblock the connection channel. The opening of the airtight member and the unblocking of the connection channel are completed during the process of connecting the connecting pipe 2 to the interface 11, eliminating the need for manual adjustment or calibration. In addition, the connection method is simple, efficient and convenient, shortening the process links and saving time during the entire anesthesia process, thereby improving anesthesia efficiency.

[0066] 2. The double sealing of the first airtight member 3 and the second airtight member 4 can ensure a good sealing effect of the connecting channel.

[0067] See also Figure 1 and Figure 2 As shown, in an optional embodiment, an air outlet 8 can be provided on the other side of the box body 1 opposite to the interface 11, and the air outlet 8 can connect the interior of the box body 1 with the external waste gas recovery device to prevent the anesthetic gas from leaking indoors.

[0068] Further, see Figure 1 and Figure 2 As shown, in anesthesia box A,

[0069] The first airtight member 3 is disposed in the connecting pipe 2, and the interface 11 pushes the first airtight member 3 open, so that the fluid can enter the interface 11 and push the second airtight member 4 open; or

[0070] The first airtight member 3 is disposed on the interface 11 . After the connecting pipe 2 pushes the first airtight member 3 open, the fluid pushes the second airtight member 4 open and enters the interface 11 .

[0071] According to the different locations of the first airtight member 3 and the second airtight member 4 , the way in which the connecting pipe 2 is connected to the interface 11 also changes accordingly.

[0072] Specifically, the first scenario is as follows: the first airtight member 3 is disposed within the connecting pipe 2, and the second airtight member 4 is disposed within the interface 11. Since the first airtight member 3 is pushed open when the connecting pipe 2 is plugged into the interface 11, and the first airtight member 3 is disposed within the connecting pipe 2, the radius of the connecting pipe 2 in this scenario is slightly larger than the radius of the interface 11. The process of docking the connecting pipe 2 with the interface 11 is the process of the interface 11 entering the interior of the connecting pipe 2. Furthermore, the interface 11 extends outward from the outer wall of the housing 1, and the length of the interface 11 extending from the outer wall of the housing 1 is set to be longer than the depth of the first airtight member 3 from the opening of the connecting pipe 2, enabling the interface 11 to push open the first airtight member 3 while extending into the connecting pipe 2.

[0073] Therefore, in the first scenario described above, the process by which the fluid enters the interior of the housing 1 is as follows: the interface 11 extends into the connecting pipe 2. As the interface 11 extends deeper, the opening of the interface 11 contacts and pushes open the first airtight member 3 in the connecting pipe 2, allowing the fluid to pass through the first airtight member 3 and enter the passage between the first airtight member 3 and the second airtight member 4, where it contacts the second airtight member 4. When the pressure from the fluid continues to increase to a critical value greater than the sealing pressure of the second airtight member 4, the fluid pushes open the second airtight member 4 and enters the housing 1. With this configuration of the anesthesia housing A, the first airtight member 3 and the second airtight member 4 can form a sealed cavity for the fluid, resulting in a good sealing effect.

[0074] In addition, in an optional embodiment, the second airtight part 4 can be set at a position close to the inner side of the box body 1. Compared with setting the second airtight part 4 at a position far away from the box body 1, the contact between the second airtight part 4 and the outside world can be minimized, thereby reducing the external contamination of the second airtight part 4.

[0075] The second scenario is: the first airtight member 3 is installed on the interface 11, and the second airtight member 4 is installed in the connecting pipe 2. In this case, the radius of the interface 11 is slightly larger than the radius of the connecting pipe 2, allowing the connecting pipe 2 to enter the interior of the interface 11 and push open the first airtight member 3. Fluid begins to flow into the connecting pipe 2 and exerts pressure on the second airtight member 4. When the pressure from the fluid exceeds the critical sealing pressure of the second airtight member 4, the fluid pushes open the second airtight member 4 and enters the interior of the housing 1.

[0076] In addition, in an optional embodiment, the length of the connecting pipe 2 can be set so that it can enter the interior of the box 1 after forming a connecting channel with the interface 11. On the premise of ensuring the sealing effect, the fluid can enter the box 1 without contacting the interface 11, thereby reducing pollution, being clean and environmentally friendly.

[0077] For example, the fluid may be an anesthetic gas, which is fed into the box 1 through the connecting channel; or,

[0078] The fluid may also be a liquid anesthetic drug, which passes through the connecting channel in liquid form and evaporates in the box 1 to anesthetize the animal.

[0079] Implementation Method 2

[0080] This embodiment also discloses an anesthesia box A. This embodiment further improves the first embodiment in that the first airtight member 3 and the second airtight member 4 can be configured as a structure in which a flexible valve 42 cooperates with an airtight ring 41 to achieve sealing between the interface 11 and the connecting channel in both docking and undocking states, eliminating the need for manual sealing during docking. Figure 1 and Figure 2 As shown, the second airtight member 4 of the anesthesia box A further includes:

[0081] An airtight ring 41 is provided on the inner wall of the connecting channel;

[0082] At least three flexible valves 42 are provided on the airtight ring 41 . In a natural state, the at least three flexible valves 42 are closed and together with the airtight ring 41 form a seal for the connecting channel.

[0083] The second airtight member 4 can be composed of an airtight ring 41 and flexible valves 42 disposed on the airtight ring 41. Specifically, at least three flexible valves 42 can be of the same size and can be combined in the same plane to form a circular sector-shaped piece structure. The flexible sector-shaped piece is pushed open under the pressure of the fluid, and its tip is bent in the direction of fluid flow, allowing the fluid to pass through the second airtight member 4.

[0084] In some embodiments, the second airtight member 4 may be configured as a one-way opening flexible valve 42 to prevent fluid from being sucked back after the fluid supply is stopped.

[0085] Optionally, the number of the flexible valves 42 of the second airtight member 4 of the anesthesia box A is 4-8.

[0086] The number of flexible valves 42 of the second airtight part 4 of the anesthesia box A is 4-8. The more flexible valves 42 there are, the closer the distance between the vertices of the fan-shaped flexible valves 42 will be after the flexible valves 42 of the second airtight part 4 are pushed open by the pipe or interface 11, and the gap between the two flexible valves 42 will also be reduced accordingly, thereby improving the sealing performance.

[0087] Optionally, the first airtight member 3 of the anesthesia box A comprises:

[0088] A disposable film (not shown) is provided on the inner wall of the connecting pipe 2 . The interface 11 pierces the disposable film so that the fluid can enter the interface 11 and push the second airtight member 4 open.

[0089] The first airtight member 3 may include a disposable film that is disposed on the inner wall of the connecting pipe 2 and can be punctured. When the connecting pipe 2 is connected to the interface 11, the interface 11 punctures the disposable film inside the connecting pipe 2, and the fluid directly enters the housing 1 after pushing open the second airtight member 4.

[0090] In particular, in some instances, when the connecting pipe 2 is disposable, providing a disposable film on its inner wall has a cost advantage over providing other more complex airtight structures, and the disposable film has better airtightness when it is not punctured.

[0091] Implementation Method 3

[0092] This embodiment also discloses an anesthesia box A. This embodiment further improves the first and second embodiments in that a supporting plate 5 is added to support the box body 1, and the connecting channel is provided on the side plate 52 of the supporting plate 5. When the box body 1 is close to the side plate 52, the interface 11 can be connected to the connecting channel. Figures 1 to 4 As shown, the anesthesia box A also includes:

[0093] The carrier plate 5 includes:

[0094] Bottom plate 51, used for placing box 1;

[0095] The side plate 52 has a through hole at a position corresponding to the interface 11 , and the through hole is used to pass the connecting pipe 2 .

[0096] The side panels 52 can be vertically mounted on the bottom panel 51. The side panels 52 are provided with through-holes for providing connection passages. The position of the through-holes on the side panels 52 corresponds to the interface 11 on the box body 1. Specifically, when the box body 1 is placed on the bottom panel 51, the height of the interface 11 on the box body 1 is the same as the through-hole. When the box body 1 is connected to the connection passage, the axis of the interface 11 and the axis of the connection passage are aligned, allowing the interface 11 to be smoothly plugged into the connection passage as the box body 1 approaches the side panels 52. The bottom panel 51 is used to support the box body 1. With the addition of positioning components, it can also limit the direction of movement of the box body 1 on the floor, allowing the interface 11 of the box body 1 to smoothly dock with the connection passage.

[0097] The supporting plate 5 set as above can limit the movement direction of the box body 1, so that when the box body 1 approaches the side panel 52, the interface 11 can be smoothly plugged into the connecting channel at one time. Compared with the existing technology, it saves the process of manual docking of the anesthesia pipeline and improves the anesthesia efficiency.

[0098] Alternatively, see Figures 2 to 4 As shown, the carrying plate 5 further includes:

[0099] The sliding auxiliary mechanism 53 is provided on the carrying plate 5 so that when the box body 1 is placed on the bottom plate 51, it can move in the direction close to the side plate 52 to connect the interface 11 with the connecting pipe 2;

[0100] The sliding auxiliary mechanism 53 is a slope 531 provided on the side of the bottom plate 51 away from the side plate 52 , and / or the sliding auxiliary mechanism 53 is a slide rail (not shown) provided on the bottom plate 51 along a direction close to or away from the side plate 52 .

[0101] The sliding auxiliary mechanism 53 provided on the supporting plate 5 can limit the movement direction of the box body 1 on the bottom plate 51, or guide the movement of the box body 1, so that the interface 11 on the box body 1 can be accurately docked with the connecting channel in the process of approaching the side plate 52.

[0102] In some embodiments, the sliding assist mechanism 53 is a ramp 531 disposed on the bottom plate 51 on a side away from the side plate 52, with the slope of the ramp 531 facing the side plate 52. When the box 1 is in contact with the bottom plate 51, its bottom can rest on the ramp 531. As the box 1 approaches the side plate 52, the bottom edge of the box 1 contacts the ramp 531 and slides along the ramp 531. As the bottom edge of the box 1 slides down the ramp 531 until it reaches the bottom of the slope and directly contacts the bottom plate 51, the interface 11 of the box 1 and the connecting channel simultaneously complete the mutual insertion action. The provision of the ramp 531 not only enables one side of the box 1 to directly connect with each other as it slides down the ramp 531, but also makes the process of pushing the box 1 toward the side plate 52 more labor-saving.

[0103] In other embodiments, the slide assist mechanism 53 may be a slide rail provided on the carrier plate 5, and a corresponding pulley or slide groove may be provided on the bottom of the box body 1. The direction of the slide rail may be perpendicular to the surface of the side panel 52. When the box body 1 is placed on the carrier plate 5, the pulley or slide groove at the bottom contacts the slide rail. As the box body 1 is pushed along the slide rail to the side panel 52, the interface 11 and the connecting channel can be aligned and connected to each other.

[0104] In addition, the above-mentioned slope 531 and slide rail can be set simultaneously on the bottom plate 51. In the process of approaching the side plate 52, the slide groove or pulley at the bottom of the box body 1 is connected to the slide rail and gradually approaches the side plate 52, and the bottom plate 51 of the box body 1 contacts the top of the slope 531 until the bottom edge of the box body 1 contacts the slope 531 and begins to slide down the slope 531. At the same time, the interface 11 on the box body 1 is connected to the connecting channel on the side plate 52. In this embodiment, the provision of the slope 531 can generate resistance to the reverse sliding of the box body 1, preventing the box body 1 from sliding off the load-bearing plate 5, and the provision of the slide rail can limit the sliding direction of the box body 1, so that the interface 11 and the connecting channel can be accurately connected.

[0105] Alternatively, see Figure 3 As shown, a first locking member 521 is provided on the side panel 52 of the anesthesia box A, and the box body 1 further includes:

[0106] A box cover 12 and a second locking member 121 provided on the box cover 12;

[0107] The first locking member 521 and the second locking member 121 cooperate with each other to lock the box cover 12 to maintain the box cover 12 in a closed state.

[0108] A first locking piece 521 is provided on the side panel 52, and a second locking piece 121 is provided on the box cover 12 of the box body 1. The first locking piece 521 and the second locking piece 121 are located at the same height, and the first locking piece 521 is located on the movement trajectory of the second locking piece 121, so that in the process of the box body 1 approaching the side panel 52, the second locking piece 121 can smoothly contact and cooperate with the first locking piece 521.

[0109] Implementation Method 4

[0110] The inventors of this application discovered that before radiotherapy begins, experimental animals need to be anesthetized and fixed in a specific position. However, existing boxes lack animal fixation devices, making it impossible to accurately fix target areas such as the neck or abdomen, which require supine exposure, thus affecting treatment effectiveness. Precision radiotherapy requires accurate positioning for each treatment. However, existing boxes lack internal positioning lines as a positioning reference, resulting in poor repeatability of each positioning.

[0111] In view of this, the present embodiment also discloses an anesthesia box A. This embodiment further improves the third embodiment in that a fixing stake 6 and a positioning line are provided. The animal can be fixed to the fixing stake 6 by a rope, and when the animal is positioned in the box 1, the positioning line can be used to assist in positioning, so that the animal can maintain the correct position for radiotherapy after receiving anesthesia. Specifically, see Figure 1 As shown, a plurality of fixing piles 6 are provided in the box 1, and the fixing piles 6 are used to fix the experimental animals;

[0112] The box 1 is marked with positioning lines, which are used to assist in positioning the experimental animals.

[0113] A fixing stake 6 can be provided inside the box 1 to secure the animal in place with a rope. This allows the animal to maintain a specific position for radiotherapy and minimize movement during treatment. A positioning line can assist in placing the animal in the correct position to ensure it is aligned with the radiotherapy center's irradiation.

[0114] In some embodiments, different numbers of positioning stakes 6 can be provided depending on the specific situation. For example, when a larger animal needs to be tied up, six positioning stakes 6 can be arranged around the inner wall of the box, leaving enough space between the six positioning stakes 6 to tie up the animal. When a smaller animal needs to be tied up, only three to four positioning stakes 6 need to be provided on the bottom surface of the box 1, and the animal can be tied to the bottom surface of the box 1 with ropes.

[0115] In an optional embodiment, the positioning lines can be cross-shaped, i.e., two perpendicular intersecting lines on the bottom of the housing 1. Each line can be graduated to the nearest millimeter, with increments from the intersection point toward the end of the line. The cross-shaped line can be positioned at the center of the bottom of the housing 1. When positioning and securing the animal, the animal can be placed and recorded at the appropriate scale position based on its positional requirements and anatomy, ensuring that the animal is centered in the radiation during treatment and maintaining good repeatability.

[0116] In a further embodiment, Figure 5As shown, after the experimental animal enters the anesthesia state, the box 1 is removed from the supporting plate 5, so that the box 1 is separated from the connecting channel, and the anesthetic gas no longer enters the box 1. At this time, the box cover 12 can be quickly opened to correctly position the animal so that the irradiation site is exposed and maintained. After the animal is fixed, the box is reinserted into the supporting plate, the gas channel is connected, and the anesthetic gas enters the box 1 to maintain low-dose anesthesia for the experimental animal. The experimental animal in the maintained anesthesia state is placed on the radiotherapy bed, and the lesions of the experimental animal are correctly radiotherapyed according to the positioning line and the position of the treatment laser light. After completing the irradiation of a single animal, the experimental animal in the other box is moved into the irradiation range by controlling the horizontal movement of the treatment bed to continue the treatment until the treatment of multiple animals is completed. In order to reduce the influence of the material of the box 1 on the energy of the radiation, the use of metal materials can be avoided.

[0117] Finally, it should be noted that those skilled in the art will appreciate that, in order to facilitate a better understanding of this patent, the embodiments of this patent set forth numerous technical details. However, even without these technical details and the various variations and modifications based on the aforementioned embodiments, the technical solutions claimed in the various claims of this patent can be substantially achieved. Therefore, in actual practice, various changes in form and detail may be made to the aforementioned embodiments without departing from the spirit and scope of this patent.

Claims

1. An anesthesia box for experimental animals, used in radiotherapy, characterized in that: include: The box and the interface provided on the box, and A connecting pipe, which can be plugged into the interface to form a connecting channel; A first airtight member and a second airtight member are provided in the connecting passage; The first air-sealing member can be pushed open when the connecting pipe is plugged into the interface, and the second air-sealing member can be pushed open by the fluid from the connecting pipe to make the connecting channel unobstructed.

2. The anesthesia box according to claim 1, characterized in that The first airtight member is disposed in the connecting pipe, and the interface pushes the first airtight member open, so that the fluid can enter the interface and push the second airtight member open; or The first airtight member is arranged on the interface. After the connecting pipe pushes the first airtight member open, the fluid pushes the second airtight member open and enters the interface.

3. The anesthesia box according to claim 1, characterized in that: The second airtight member comprises: An airtight ring, arranged on the inner wall of the connecting channel; At least three flexible valves are arranged on the airtight ring. In a natural state, at least three flexible valves are closed and form a seal for the connecting channel together with the airtight ring.

4. The anesthesia box according to claim 3, characterized in that The number of the flexible valves of the second airtight member is 4-8.

5. The anesthesia box according to claim 3, characterized in that: The structure of the first airtight member is consistent with that of the second airtight member.

6. The anesthesia box according to claim 3, characterized in that: The first airtight member comprises: A disposable film is arranged on the inner wall of the connecting pipe. The interface punctures the disposable film so that the fluid can enter the interface and push the second airtight component open.

7. The anesthesia box according to any one of claims 1 to 6, characterized in that: The anesthesia box also includes: Loading plate, comprising: A bottom plate, used for placing the box; A side plate is provided with a through hole at a position corresponding to the interface, and the through hole is used to pass the connecting pipe.

8. The anesthesia box according to claim 7, characterized in that: The carrying plate further comprises: a sliding auxiliary mechanism, provided on the carrying plate, so that when the box is placed on the bottom plate, it can move in a direction close to the side plate to dock the interface with the connecting pipe; The sliding auxiliary mechanism is a slope provided on a side of the bottom plate away from the side plate, and / or the sliding auxiliary mechanism is a slide rail provided on the bottom plate in a direction close to or away from the side plate.

9. The anesthesia box according to claim 7, characterized in that: The side panel is provided with a first locking member, and the box body further comprises: A box cover and a second locking member provided on the box cover; The first locking member and the second locking member cooperate with each other to lock the box cover in a closed state.

10. The anesthesia box according to claim 1, characterized in that: Several fixing piles are provided in the box body, and the fixing piles are used to fix the experimental animals; Positioning lines are marked inside the box to assist in positioning the experimental animals.