Quantitative lung atomization device
By designing a lung quantitative atomization device and using a water bath device or a diffusion dryer to adjust the temperature and humidity of atomized drugs, the problem of mixed drug delivery experiments was solved, and the mixed drug delivery effect of multiple drugs in the lungs was achieved, which improved the controllability and accuracy of the treatment effect.
Patent Information
- Application Number
- CN202422691464.3
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-11-05
- Publication Date
- 2025-09-02
- Estimated Expiration
- 2034-11-05
AI Technical Summary
The prior art is difficult to achieve experimental research on the mixed administration of a variety of atomized drugs under different temperature and humidity conditions, which affects the therapeutic effect.
A lung quantitative atomization device is designed, including a ventilator, an expiratory joint, an inspiratory joint and multiple atomization channels. The temperature and humidity of the drug are adjusted through a water bath device or a diffusion dryer to achieve a mixed delivery experiment of a variety of atomized drugs in the lungs.
The mixed administration effect of a variety of atomized drugs under different temperature and humidity conditions has been achieved, and the controllability and accuracy of the treatment effect have been improved.
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Figure CN223287270U_ABST
Abstract
Description
Technical Field
[0001] The present application relates to the field of atomization devices, and in particular to a pulmonary quantitative atomization device. Background Art
[0002] Respiratory diseases are common and frequently occurring diseases that seriously endanger human health and impose a heavy burden on society and the national economy.
[0003] Aerosol inhalation therapy is an important treatment for respiratory diseases and is widely used both domestically and internationally due to its clinical advantages. Aerosol inhalation is a direct drug delivery method targeting the respiratory tract and lungs. It offers advantages such as rapid onset of action, high local drug concentrations, low dosage, ease of use, and minimal systemic adverse reactions. It has become a key treatment for respiratory diseases.
[0004] During the research and development phase, the effects of nebulized drugs need to be verified through animal respiratory administration. Sometimes, multiple nebulized drugs need to be mixed and used. Different nebulized drugs may achieve the best therapeutic effect under different temperature conditions. Multiple nebulized drugs acting simultaneously in the lungs may have a better therapeutic effect. Therefore, it is also necessary to study the effects of mixed administration of multiple drugs.
[0005] Therefore, a device is needed to conduct mixed drug administration experiments of multiple aerosolized drugs. Utility Model Content
[0006] In view of the above problems, the present application provides a pulmonary quantitative atomization device that can conduct mixed administration experiments of multiple atomized drugs.
[0007] The present application provides a lung quantitative atomization device that adopts the following technical solutions:
[0008] A pulmonary quantitative atomization device, comprising:
[0009] Optionally, it includes a ventilator, an exhalation connector, an inhalation connector and multiple atomization channels, wherein one end of the exhalation connector is connected to the exhalation port of the ventilator, and the other end is connected to one end of the multiple atomization channels; one end of the inhalation connector is connected to the inhalation port of the ventilator, and the other end is connected to the other end of the multiple atomization channels;
[0010] The ports at one end of the multiple atomization channels close to the exhalation connector are used to connect to the nebulizer, and the ports at one end of the multiple atomization channels close to the inhalation connector are all connected to a lung cannula.
[0011] Optionally, the atomization channel includes an exhalation channel and an inhalation channel, and a water bath device may be provided between the exhalation channel and the inhalation channel, and the water bath device is used to perform water bath heating on the aerosol.
[0012] Optionally, the water bath device includes a water bath bottle and a water bath cup arranged in the water bath bottle, and the exhalation channel is connected to the lower end of the water bath bottle, and the inhalation channel is connected to the upper end of the water bath bottle.
[0013] Optionally, the water bath device can be replaced with a diffusion dryer for adjusting humidity.
[0014] Optionally, a plurality of the pulmonary cannulas are arranged in parallel at one end away from the nebulization channel.
[0015] In summary, the present application includes the following beneficial technical effects: a pulmonary quantitative nebulization device that simultaneously conducts mixed administration experiments of multiple nebulized drugs under different physical conditions, realizing the study of the effects of direct nebulized mixed administration of multiple nebulized drugs in the lungs; by setting a water bath device or a diffusion dryer between the nebulization channels, the study of the effects of mixed administration of multiple nebulized drugs under different temperature or humidity conditions is realized. BRIEF DESCRIPTION OF THE DRAWINGS
[0016] Figure 1 It is a schematic diagram of the overall structure of an embodiment of the present application.
[0017] Explanation of the accompanying symbols: 1. ventilator; 2. exhalation connector; 3. inhalation connector; 4. atomization channel; 41. exhalation channel; 42. inhalation channel; 43. water bath device; 5. nebulizer; 6. lung intubation. DETAILED DESCRIPTION
[0018] To make the objectives, technical solutions, and advantages of the present invention more clear, the technical solutions of the present invention will be clearly and completely described below in conjunction with the accompanying drawings of the embodiments of the present invention. Obviously, the described embodiment is only one embodiment of the present invention, not all embodiments. Based on the described embodiment of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.
[0019] Unless otherwise defined, technical or scientific terms used in the present invention shall have the same meaning as commonly understood by one of ordinary skill in the art to which the present invention belongs.
[0020] This embodiment provides a lung quantitative atomization device.
[0021] Reference Figure 1 A pulmonary quantitative nebulization device includes a ventilator 1, an exhalation connector 2, an inhalation connector 3 and multiple nebulization channels 4.
[0022] Each atomization channel 4 includes an exhalation channel 41, an inhalation channel 42, and a water bath device 43 disposed between the exhalation channel 41 and the inhalation channel 42. The water bath device 43 includes a water bath bottle and a water bath cup disposed within the water bath bottle. The exhalation channel 41 is connected to the lower end of the water bath bottle, and the inhalation channel 42 is connected to the upper end of the water bath bottle, so as to heat the aerosol formed by the atomized drug flowing from the exhalation channel 41 through the inhalation channel 42 in the water bath.
[0023] The expiratory connector 2 is connected to multiple expiratory channels 41, the inspiratory connector 3 is connected to multiple inspiratory channels 42, and the expiratory connector 2 is connected to the expiratory end of the ventilator 1, and the inspiratory connector 3 is connected to the inspiratory end of the ventilator 1. The animals are in an anesthetized state during the experiment. This setting can be used to simulate the breathing movements of the experimental animals during the experiment, thereby assisting in delivering the atomized drugs to the lungs of the experimental animals.
[0024] The ends of the multiple exhalation channels 41 away from the water bath are connected to a nebulizer 5, such as a nebulizer needle, etc. The ends of the multiple inhalation channels 42 away from the water bath are connected to a pulmonary cannula 6, and the ends of the multiple pulmonary cannula 6 away from the inhalation channels 42 are arranged in parallel so as to be inserted into the lungs of the experimental animals.
[0025] When conducting an experiment, the lung cannula 6 is first inserted into the lungs of the experimental animal in a coma, and then the nebulizer 5 is used to supply medicine. With the assistance of the ventilator 1, the atomized medicine heated in the water bath device 43 is delivered to the lungs of the experimental animal and mixed in the lungs, thereby achieving mixed administration of multiple atomized medicines. The effect of mixed administration of multiple atomized medicines at a certain temperature can be judged by the reaction of the experimental animal.
[0026] During actual use, the water bath device 43 can also be replaced by other related regulating devices that can adjust the drug administration environment, such as a diffusion dryer for adjusting the humidity, which is used to conduct experiments on the mixed administration effects of multiple atomized drugs under different humidity conditions; according to experimental needs, multiple regulating devices can also be connected in series to study the mixed administration effects of multiple atomized drugs under multiple drug administration environments.
[0027] The above are all preferred embodiments of the present application, and are not intended to limit the scope of protection of the present application. Therefore, any equivalent changes made based on the structure, shape, and principle of the present application should be included in the scope of protection of the present application.
Claims
1. A pulmonary quantitative atomization device, characterized in that: The invention comprises a ventilator (1), an exhalation connector (2), an inhalation connector (3) and a plurality of atomizing channels (4), wherein one end of the exhalation connector (2) is connected to the exhalation port of the ventilator (1), and the other end is communicated with one end of the plurality of atomizing channels (4); one end of the inhalation connector (3) is connected to the inhalation port of the ventilator (1), and the other end is communicated with the other end of the plurality of atomizing channels (4); The ports of one end of the multiple atomization channels (4) close to the exhalation connector (2) are used to connect to the nebulizer (5), and the ports of one end of the multiple atomization channels (4) close to the inhalation connector (3) are all connected to a lung cannula (6).
2. A lung metered dose atomization device according to claim 1, characterized in that: The atomization channel (4) includes an exhalation channel (41) and an inhalation channel (42). A water bath device (43) can be provided between the exhalation channel (41) and the inhalation channel (42). The water bath device (43) is used to heat the aerosol in a water bath.
3. A lung metered dose atomization device according to claim 2, characterized in that: The water bath device (43) includes a water bath bottle and a water bath cup arranged in the water bath bottle, and the exhalation channel (41) is connected to the lower end of the water bath bottle, and the inhalation channel (42) is connected to the upper end of the water bath bottle.
4. A lung metered dose atomization device according to claim 2, characterized in that: The water bath device (43) can be replaced by a diffusion dryer for adjusting humidity.
5. The pulmonary metered dose atomization device according to claim 1, characterized in that: The plurality of pulmonary cannulas (6) are arranged in parallel at one end away from the atomization channel (4).