Conical drug eluting balloon dilatation catheter

Abstract

The utility model discloses a conical drug eluting balloon dilatation catheter, and relates to the technical field of medical instruments. In order to solve the problems that in the prior art, a balloon cannot be completely attached to the inner wall of a blood vessel and medicine runs off, the conical medicine eluting balloon dilatation catheter is mainly structurally characterized in that the balloon is in a three-section conical shape, and the conicity of the three-section conical shape changes in sequence to be matched with the diameter change of the blood vessel; and a gauze layer is coated outside the balloon and is used for carrying medicines. During use, the corresponding use sections of the three conical saccules can be selected according to the position of a lesion blood vessel, the thickness change of the blood vessel and the area of a lesion part. After the balloon is inserted into a blood vessel, blood in the blood vessel circulates so as to continuously wash the surface of the balloon, the gauze layer is coated on the surface of the balloon, and the medicine is attached to the gauze layer, so that the loss of the medicine amount can be reduced, and the treatment effect is improved. The conical drug eluting balloon dilatation catheter is simple in structure and high in applicability.

Description

TECHNICAL FIELD

[0001] The utility model relates to medical instrument technical field, more particularly, a kind of tapered drug eluting balloon dilatation catheter. BACKGROUND

[0002] Atherosclerosis is the most common pathological change form of human vascular aging, its characteristic is that artery wall thickening hard, lose elasticity and lumen shrink, mainly involving large and medium-sized arteries, lower extremity arteries, cerebral arteries and coronary arteries and systemic arteries. With the continuous progress of atherosclerosis, when involving vascular lumen stenosis is greater than 75%, corresponding organ ischemia symptoms will appear. In order to effectively relieve stenosis and improve ischemia symptoms, currently, drug eluting balloon dilatation catheter is used to physically dilate stenosis lesion and adhere the drug carried on the surface of balloon to the inner wall of blood vessel to relieve arterial lumen stenosis and prevent restenosis caused by intimal hyperplasia after arterial dilation.

[0003] Balloon dilatation catheter is a soft catheter with inflatable balloon at head end, the main structure of current balloon dilatation catheter includes balloon, catheter and double-lumen catheter seat three parts (as the utility model is to improve the balloon part of existing balloon dilatation catheter, other components are the same as existing balloon dilatation catheter, so not marked in the figure), which is commonly used to dilate stenotic arterial lumen in human body under image guidance. In the case of not inflation, drug eluting balloon catheter will enter the diseased blood vessel, when the balloon is sent to the diseased blood vessel, the balloon can be quickly filled with the catheter, so that the drug coating on the surface of the balloon is tightly attached to the inner wall of the blood vessel lesion area, and after successful treatment, the balloon can be retracted to withdraw the balloon catheter to the outside of the body.

[0004] The current drug eluting balloon dilatation catheter finds two deficiencies: 1. When using balloon dilatation catheter, the balloon needs to be sent to the blood vessel lesion, and when the balloon is inserted into the blood vessel, the blood in the blood vessel will flow and continuously wash the drug coating on the surface of the balloon, when the coating balloon reaches the diseased blood vessel, the drug amount on the balloon will be lost in large quantities, resulting in decreased treatment effect. 2. The dilatation balloon is a cylindrical dilatation balloon with the same diameter of two end lumens, but in actual interventional surgery treatment, it is found that some blood vessels of human body are tapered (blood vessel gradually thins from proximal end to distal end, and there is a difference in diameter of two ends), if conventional balloon is selected, it may cause insufficient expansion or arterial rupture and perforation at proximal end or distal end of blood vessel, which makes interventional doctors helpless when selecting suitable drug eluting balloon for tapered blood vessel stenosis, and cannot select the most suitable drug eluting balloon dilatation catheter for treatment.

[0005] The patent with publication number CN203609738U discloses a tapered balloon dilatation catheter, the balloon of which is tapered, the proximal end balloon diameter of which is larger than the distal end balloon diameter, preferably the proximal end balloon diameter of the tapered balloon is 0.5mm larger than the distal end balloon diameter, and the dilatation balloon surface is provided with a polymer carrying an anti-proliferation drug. The tapered balloon dilatation catheter can better solve the stenosis of the tapered blood vessel.

[0006] The tapered balloon of the utility model is fixed taper, and cannot be simultaneously adapted to large taper blood vessels and small taper blood vessels, and the application range is narrow. SUMMARY

[0007] In view of the above problems, the technical idea adopted by the utility model to solve the technical problems is:

[0008] A three-section tapered balloon with multiple tapers is designed to adapt to the thickness change of different blood vessels under different conditions, and a gauze layer for carrying drugs is coated outside the balloon to reduce the loss of drug amount before reaching the diseased blood vessel.

[0009] The specific scheme is as follows:

[0010] A tapered drug-eluting balloon dilatation catheter comprises a balloon and a catheter, the catheter penetrates through the balloon and extends to the outside of the balloon, the balloon is three-section tapered, the tapers of the three-section tapered balloon change in turn to adapt to the diameter change of the blood vessel, and the balloon is coated with a gauze layer for carrying drugs.

[0011] Further, the three-section tapered balloon comprises a first arc section, a second arc section and a third arc section connected in turn from the proximal end to the distal end.

[0012] Preferably, the first arc section and the second arc section form a middle taper, and the middle taper is 10-20 degrees.

[0013] Preferably, the second arc section and the third arc section form a small taper, and the small taper is 0-10 degrees.

[0014] Preferably, the first arc section and the third arc section form a large taper, and the large taper is 20-30 degrees.

[0015] By adopting the above technical scheme, the utility model has the following technical effects:

[0016] The utility model provides a kind of tapered drug eluting balloon dilatation catheter, including balloon and catheter, catheter is through balloon, and extend to balloon outside, balloon is three taper, the taper of three taper changes in turn to adapt the diameter variation of blood vessel;Balloon is covered with gauze layer, for carrying drug.In use, the use section of corresponding three taper balloon can be selected according to the location of pathological blood vessel, the thickness variation of the blood vessel and the area of pathological place.When balloon is inserted into blood vessel, blood in blood vessel will flow and thus constantly washes the surface of balloon, the gauze layer covered on the surface of balloon, drug is attached on gauze layer, can reduce the loss of drug amount, to improve treatment effect.The utility model discloses a kind of tapered drug eluting balloon dilatation catheter structure simple, strong applicability, can effectively improve use effect. BRIEF DESCRIPTION OF DRAWINGS

[0017] In order to more clearly illustrate the technical solutions of the embodiments of the present application, the drawings used in the embodiments will be briefly introduced as follows.

[0018] Figure 1 is a structure schematic view of a tapered drug eluting balloon dilatation catheter provided by the embodiments of the present application;

[0019] Figure 2 is a perspective view of a tapered drug eluting balloon dilatation catheter provided by the embodiments of the present application;

[0020] Figure 3 is an exploded schematic view of a tapered drug eluting balloon dilatation catheter provided by the embodiments of the present application;

[0021] Figure 4 is a structure schematic view of three taper balloon provided by the embodiments of the present application;

[0022] Figure 5 is a middle taper use schematic view of a tapered drug eluting balloon dilatation catheter provided by the embodiments of the present application;

[0023] Figure 6 is a small taper use schematic view of a tapered drug eluting balloon dilatation catheter provided by the embodiments of the present application;

[0024] Figure 7 is a large taper use schematic view of a tapered drug eluting balloon dilatation catheter provided by the embodiments of the present application;

[0025] Figure 8 is a sectional view of three taper balloon and gauze layer provided by the embodiments of the present application;

[0026] Figure 9 is a real object view of existing balloon dilatation catheter;

[0027] Icon: balloon 1; first arc segment 11; second arc segment 12; third arc segment 13; gauze layer 14; catheter 2; double-lumen catheter seat 3. DETAILED DESCRIPTION

[0028] To make the objectives, technical solutions, and advantages of the embodiments of the present application clearer, the following will briefly describe the technical solutions in the embodiments of the present application with reference to the accompanying drawings. Figures 1-8 The embodiments described are only some of the embodiments of the present application, rather than all the embodiments.

[0029] It should be noted that similar reference numerals and letters in the following drawings denote similar items, and thus, once an item is defined in one drawing, it need not be further defined and explained in subsequent drawings.

[0030] In the description of the present application, it should be noted that the terms "center", "upper", "lower", "vertical", "horizontal", "inner", "outer", and the like indicate the orientation or positional relationship shown in the drawings, or the orientation or positional relationship in which the product of the present application is usually placed, and are merely for the convenience of describing the present application and simplifying the description, and thus cannot be understood as indicating or implying that the device or element referred to must have a particular orientation, be constructed and operated in a particular orientation, and thus cannot be understood as limiting the present application.

[0031] In the description of the present application, it should also be noted that, unless otherwise explicitly specified and limited, the terms "arrange", "mount", "connect", and "connect" should be understood broadly.

[0032] EMBODIMENT

[0033] The inventors have found that, at present, the vascular interventional treatment for peripheral arterial ischemic diseases mostly uses a drug-eluting balloon dilatation catheter to physically dilate the lumen, and at the same time, the drug on the surface of the balloon dilatation catheter is attached to the inner wall of the blood vessel to avoid the proliferation of arterial intimal cells causing post-treatment arterial restenosis. However, since the human body artery gradually thins out after being emitted from the heart, the diameter of the arterial lumen also gradually thins out from thick to thin. After being expanded by the currently used drug-eluting balloon dilatation catheter, the diameters of the distal end and the proximal end of the balloon are the same, which does not conform to the characteristics of the gradual thinning of the human body artery. The traditional drug-eluting balloon dilatation catheter cannot completely attach to the inner wall of the blood vessel, and cannot achieve satisfactory treatment effect, and also causes drug waste. When the balloon is inserted into the blood vessel, the blood flow in the blood vessel will continuously flush the drug coating on the surface of the balloon. When the coated balloon reaches the diseased blood vessel, the amount of drug on the balloon has actually been largely lost, resulting in a decrease in treatment effect. Therefore, the present application provides a tapered drug-eluting balloon dilatation catheter which can adapt to the change of the blood vessel and reduce drug loss.

[0034] In the embodiments of the present application, please refer toFigure 1 、 Figure 2 and Figure 3 , Figure 1 is a structural schematic diagram of a tapered drug-eluting balloon dilatation catheter provided by an embodiment of the present application; Figure 2 is a perspective view of a tapered drug-eluting balloon dilatation catheter provided by an embodiment of the present application; Figure 3 is an exploded schematic diagram of a tapered drug-eluting balloon dilatation catheter provided by an embodiment of the present application. The tapered drug-eluting balloon dilatation catheter comprises a balloon 1, a catheter 2, and a double-lumen catheter hub 3. One end of the catheter 2 is connected with the balloon 1, and the other end is connected with the double-lumen catheter hub 3. The catheter penetrates through the balloon and extends to the outside of the balloon. The balloon dilatation catheter is a common prior art. The present application improves the balloon part of the existing balloon dilatation catheter. The other components and their connection modes are the same as those of the existing balloon dilatation catheter, which can be realized by those skilled in the art, and will not be described here.

[0035] It is worth noting that the balloon is three-section tapered, and the taper of the three-section tapered balloon changes in turn to adapt to the change in the diameter of the blood vessel. The balloon is coated with a gauze layer 14 for carrying drugs. In use, the use section of the three-section tapered balloon 1 can be selected according to the location of the diseased blood vessel, the change in the thickness of the blood vessel, and the area of the diseased part. When the balloon is inserted into the blood vessel, the blood in the blood vessel will flow through and continuously flush the surface of the balloon. The gauze layer 14 coated on the surface of the balloon and the drugs attached to the gauze layer 14 can reduce the loss of drug amount and improve the treatment effect.

[0036] In the embodiments of the present application, please refer to Figure 4 , Figure 4 is a structural schematic diagram of a three-section tapered balloon provided by an embodiment of the present application. The shape of the balloon is improved in the present application. The three-section tapered balloon 1 is a hollow whole, which comprises a first arc section 11, a second arc section 12, and a third arc section 13 connected in turn from the proximal end to the distal end. The diameter of the proximal end is greater than that of the distal end.

[0037] It should be noted that the calculation formula of the taper is: taper = (large diameter - small diameter) / height. The first arc section 11 and the second arc section 12 form a medium taper, and the medium taper is 10-20 degrees. The second arc section 12 and the third arc section 13 form a small taper, and the small taper is 0-10 degrees. The first arc section 11 and the third arc section 13 form a large taper, and the large taper is 20-30 degrees.

[0038] The difference between the small diameter of the second arc segment 12 and the large diameter of the third arc segment 13 divided by the sum of the second arc segment 12 and the third arc segment 13 is the minimum taper value; the difference between the small diameter of the first arc segment 11 and the large diameter of the third arc segment 13 divided by the length of the entire balloon is the maximum taper value; and the difference between the small diameter of the first arc segment 11 and the large diameter of the second arc segment 12 divided by the sum of the first arc segment 11 and the second arc segment 12 is the intermediate taper value.

[0039] In the embodiments of the present application, please refer to Figure 5 , Figure 6 and Figure 7 , Figure 5 is a middle taper use schematic diagram of a tapered drug-eluting balloon dilatation catheter provided by the embodiments of the present application; Figure 6 is a small taper use schematic diagram of a tapered drug-eluting balloon dilatation catheter provided by the embodiments of the present application; Figure 7 is a large taper use schematic diagram of a tapered drug-eluting balloon dilatation catheter provided by the embodiments of the present application. When the thickness of the diseased blood vessel changes greatly or the diseased area is large, a large taper can be used; when the thickness of the diseased blood vessel changes little or the diseased area is small, a small taper can be used; when the diseased blood vessel is at a bifurcation position, a middle taper can be used.

[0040] In the embodiments of the present application, please refer to Figure 8 , Figure 8 is a cross-sectional view of a three-segment tapered balloon and a gauze layer provided by the embodiments of the present application. The outer surface of the balloon is bonded and covered with a gauze layer 14 for carrying drugs. The gauze layer 14 is a grid structure similar to a screen window, made of nylon material, and drugs such as paclitaxel that control cell proliferation are coated on the gauze layer 14 to increase the friction between the drugs and the three-segment tapered balloon 1. The drugs attached to the gauze layer 14 can reduce the loss of drug amount and improve the treatment effect.

[0041] Application case

[0042] The interventional physician transmits the three-segment tapered balloon 1 to the diseased site through the arterial blood vessel (femoral artery or carotid artery), selects different use segments according to the actual situation of the patient's blood vessel, accurately positions, and performs balloon dilatation. Under the action of pressure, the three-segment tapered balloon 1 extrudes the atherosclerotic plaque to the blood vessel wall, and the drugs on the gauze layer 14 adhere to the blood vessel wall, thereby relieving and treating local luminal stenosis and improving blood flow.

[0043] The above only describes the preferred embodiments of the present application and is not intended to limit the present application. Those skilled in the art can make various modifications and changes to the present application. Any modification, equivalent replacement, improvement, etc. made within the spirit and principles of the present application shall be included in the protection scope of the present application.

Claims

1. A tapered drug-eluting balloon dilation catheter, comprising a balloon (1) and a catheter (2) which penetrates through the balloon (1) and extends outside the balloon (1), characterized in that, the balloon (1) is three-section tapered, and the taper of the three-section tapered balloon changes in turn to adapt to the change of the diameter of the blood vessel; the balloon (1) is coated with a wire mesh layer (14) for carrying drugs.

2. The tapered drug eluting balloon dilation catheter of claim 1, wherein, The three-section tapered balloon (1) comprises a first arc section (11), a second arc section (12) and a third arc section (13) connected in turn from the proximal end to the distal end.

3. The tapered drug eluting balloon dilation catheter of claim 2, wherein, The first arc section (11) and the second arc section (12) form a medium taper, and the medium taper is 10-20 degrees.

4. The tapered drug eluting balloon dilation catheter of claim 2, wherein, The second arc section (12) and the third arc section (13) form a small taper, and the small taper is 0-10 degrees.

5. The tapered drug eluting balloon dilation catheter of claim 2, wherein, The first arc section (11) and the third arc section (13) form a large taper, and the large taper is 20-30 degrees.

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