Sampling swab capable of eluting nucleic acid

Abstract

The utility model relates to a sampling swab capable of eluting nucleic acid, which comprises a sampling head and a sampling handle, the sampling head comprises a porous outer wall and a hollow interior, the sampling handle is provided with a hollow pipeline, one end of the hollow pipeline is directly communicated with the hollow interior, the other end of the hollow pipeline is provided with a sealing film, and liquid is sealed in the hollow pipeline. The sampling swab and the eluent are integrated, the hollow parts of the sampling swab and the eluent are directly communicated, and the structure is simple; after sampling, the liquid sealed in the sampling swab can be used for eluting the sample only by puncturing the sealing film on the sampling swab, so that the sampling swab is simple to operate and can be applied to sampling of an oral cavity or a nasal cavity.

Description

TECHNICAL FIELD

[0001] The utility model relates to a sampling swab capable of eluting nucleic acid, belonging to the technical field of in vitro detection. BACKGROUND

[0002] The sampling swab is mainly suitable for collecting and transporting samples before inspection and analysis. Commonly seen sampling swabs such as nasal swabs and throat swabs are used to collect secretion samples from the nose or throat. The swab is similar to a cotton swab, and the head thereof is provided with an adsorptive material to facilitate sample adhesion. The swab with the adhered sample is transferred to a test tube that can be sealed and sterile to be used for subsequent sample extraction and detection. Usually, a liquid medium is added dropwise into the test tube to elute the sample, and at the same time, the detection of the sample is prevented from being affected by changes in the sample before detection. Since the swab and the liquid medium are stored and used separately, it is inconvenient to operate in practice and is easily contaminated by the outside world.

[0003] Document CN209360742U discloses a sampling device including a liquid storage column and a sampling rod arranged in an up-down manner. After collecting the sample, the liquid in the liquid storage column flows down along the outside of the sampling rod by piercing the liquid storage column, and flushes the sample. Document CN116429474A discloses a microstructure sampling device including a piston and a cylinder body that can move relative to each other. The end of the cylinder body away from the piston is a sampling head, and the piston stores a buffer solution. After collecting the sample, the piston and the cylinder body are moved relative to each other to pierce the membrane of the piston. The buffer solution in the piston enters the communication hole of the cylinder body along the communication hole, and flows out from the transverse hole before reaching the sampling head, thereby flushing the sample on the sampling head from the outside. In the above documents, the liquid mainly flows through the sampling head from the outside, and the sample elution is not complete, and the structure of the sampling device is relatively complex.

[0004] Document CN217244510U discloses a cotton swab for swab sample collection. The cotton swab body is composed of a cotton swab head, a cotton swab rod, and a cotton swab handle in sequence. The inside of the cotton swab rod forms a liquid containing cavity, and the liquid is stored in the containing cavity. The inside of the cotton swab handle forms a sharp. By moving the cotton swab handle towards the sealing film, the sharp pierces the sealing film, and the liquid in the containing cavity flows to the cotton swab head, thereby wetting the cotton swab head. In the above document, the liquid is mainly used to wet the sampling head, rather than to elute the sample.

[0005] Therefore, there is still a need to develop a sampling swab that integrates sample collection and elution in one, with a simple structure and convenient use. UTILITY MODEL CONTENT

[0006] The utility model provides a sampling swab that integrates sample collection and elution in one, with a simple structure and convenient use, which can be applied to oral or nasal sampling, comprising:

[0007] The sampling head and the sampling handle, the sampling head comprises a porous outer wall and a hollow interior, the sampling handle has a hollow pipe, one end of the hollow pipe is directly communicated with the hollow interior of the sampling head, the other end of the hollow pipe is provided with a sealing film, and a liquid is sealed in the hollow pipe.

[0008] Preferably, the porous outer wall has a thickness of 0.8-1mm, and the hole channel of the hole of the porous outer wall gradually increases from inside to outside, so that the liquid forms large droplets when leaving the hole, and it is easier to take away the sample on the sampling head.

[0009] Preferably, the arrangement of the holes on the porous outer wall is that the farther from the one end of the sampling handle, the denser, because the one end of the sampling head far from the sampling handle contacts the sampling part first during sampling, so that more samples are generally attached, and more liquid is preferably used to wash the end of the sampling head during elution.

[0010] Preferably, the material of the sampling head can be selected from polyamide, polyurethane, acetate fiber and polyester fiber.

[0011] Preferably, the sampling head is in an overall elliptical shape, the length is 10-12mm, and the width of the widest part is 5-6mm.

[0012] Preferably, the outer diameter of the sampling handle is 3-5mm, the inner diameter is 1.5-3mm, the length is 80-120mm, and the length of the liquid is 60-80mm.

[0013] Preferably, the sealing film can be punctured.

[0014] Preferably, the liquid is a diluent.

[0015] The liquid in the sampling swab is tightly adsorbed in the hollow pipe due to the action of air pressure, when the sealing film is punctured, air enters the cavity, the original air pressure changes, the sample diluent in the pipe is discharged from the sampling head pores below the pipe, and the sample collected outside the sampling head is washed out or dissolved.

[0016] The utility model discloses the beneficial effects of:

[0017] The sampling head and the eluent are integrated, and the hollow parts of the two are directly communicated, so that the structure is simple.

[0018] After sampling, only the sealing film on the sampling swab is punctured, the liquid sealed in the sampling swab can be used to elute the sample, and the operation is simple. BRIEF DESCRIPTION OF DRAWINGS

[0019] Figure 1 The structure diagram of the embodiment of the utility model.

[0020] Figure 2 The use state diagram of the embodiment of the utility model.

[0021] In the drawing, 101 is a sampling head, 1011 is a porous outer wall, 1012 is a hole, 1013 is a hollow interior, 102 is a sampling handle, 103 is a sealing film, 104 is a liquid, and A is a pressing head. DETAILED DESCRIPTION

[0022] The technical scheme of the utility model will be further explained according to specific embodiments. The protection scope of the utility model is not limited to the following embodiments, and these examples are listed only for exemplary purposes and do not limit the utility model in any way.

[0023] The utility model will be further explained in detail through embodiments.

[0024] Reference Figure 1 The sampling swab of the utility model comprises a sampling head 101 and a sampling handle 102, the sampling head 101 comprises a porous outer wall 1011 and a hollow interior 1013, the sampling handle 102 has a hollow pipeline, one end of the hollow pipeline is directly communicated with the hollow interior of the sampling head, the other end of the hollow pipeline has a sealing film 103, and the hollow pipeline is sealed with a liquid 104 for elution, which can be a sample diluent, used for eluting a sample.

[0025] The porous outer wall 1011 has a certain thickness, and the thickness is 0.8-1mm. The hole channel of the hole of the porous outer wall gradually increases from inside to outside, the inner diameter of the innermost part of the hole channel is 0.15mm, so that the sample is not easy to pass through the hole and enter the hollow interior of the sampling head; the inner diameter of the outermost part of the hole channel is 0.2mm, and a part of the sample can be intercepted. The arrangement of the holes 1012 on the porous outer wall is denser (not shown in the figure) away from the end of the sampling handle, because the end of the sampling head away from the sampling handle contacts the sampling part first during sampling, so more samples are generally attached, and more liquid should be used for the end of the sampling head during elution. The sampling head is in the shape of an ellipse as a whole, the length is 12mm, and the width of the widest part is 6mm. The material of the sampling head 101 is polyamide, which has low water absorption, so that the sample is easy to be washed down. The outer diameter of the sampling handle is 4mm, the inner diameter is 2mm, and the length of the liquid is 70mm. The material of the sampling handle is PP.

[0026] During use, the sample is first collected by the sampling head 101, and then the sealing film 103 on the sampling handle is poked by the pressing head A, at this time, the elution liquid in the sampling handle flows downward due to the action of gravity, as shown in Figure 2 Finally, the sample collected outside the sampling head is washed out or dissolved.

Claims

1. A sample swab elutable of nucleic acid, comprising a sampling head and a sampling handle, characterized in that, The sampling head comprises a porous outer wall and a hollow interior, the sampling handle has a hollow pipe, one end of the hollow pipe is directly communicated with the hollow interior, the other end of the hollow pipe is provided with a sealing film, and the hollow pipe is sealed with a liquid.

2. The sampling swab of claim 1, wherein, The porous outer wall has a certain thickness, and the hole channel of the hole of the porous outer wall gradually increases from inside to outside.

3. The sampling swab of claim 2, wherein, The inner diameter of the innermost part of the hole channel is 0.1-0.2mm, and the inner diameter of the outermost part is 0.15-0.25mm.

4. The sampling swab of claim 1, wherein, The arrangement of the holes on the porous outer wall is denser away from the end of the sampling handle.

5. The sampling swab of claim 1, wherein, The material of the sampling head can be selected from polyamide, polyurethane, acetate fiber and polyester fiber.

6. The sampling swab of claim 1, wherein, The sampling head is in an overall elliptical shape, the length is 10-12mm, and the width at the widest part is 5-6mm.

7. The sampling swab of claim 1, wherein, The outer diameter of the sampling handle is 3-5mm, the inner diameter is 1.5-3mm, and the length is 80-120mm, and the length of the liquid is 60-80mm.

8. The sampling swab of claim 1, wherein, The sealing film can be punctured.

9. The sampling swab of claim 1, wherein, The liquid is a sample diluent.

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