Device for nursing experimental animal after respiratory tract experiment
By combining an inclined insulated nursing table with an auxiliary breathing device, the problems of airway obstruction and unstable body temperature in animals under anesthesia are solved, improving the safety of laboratory animals and the reliability of experimental data. It is suitable for laboratory animals of different sizes.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- GUANGDONG YUEWEI EDIBLE FUNGI TECH
- Filing Date
- 2025-03-17
- Publication Date
- 2026-05-05
AI Technical Summary
In biomedical research, insufficient care for animals under anesthesia after the experiment can lead to risks such as airway obstruction and hypothermia, affecting the reliability of experimental results and animal health.
A device is provided that includes an inclined heated nursing table, a support component, and an auxiliary breathing component. By using an adjustable inclined heated nursing table and an auxiliary breathing component, combined with an electrothermal heating component, the device ensures unobstructed breathing and stable body temperature for laboratory animals during anesthesia recovery.
It improves the survival rate and health status of laboratory animals, reduces the risk of airway obstruction, ensures the quality and stability of experimental data, is applicable to laboratory animals of different sizes, and is simple and efficient to operate.
Smart Images
Figure CN224193602U_ABST
Abstract
Description
Technical Field
[0001] This utility model relates to the field of biomedical experimental equipment, specifically to a device for caring for experimental animals after respiratory experiments. Background Technology
[0002] In biomedical research, endotracheal intubation experiments in mice and rats are a crucial method for studying lung diseases and drug efficacy. However, there are significant shortcomings in the post-experiment care of animals under anesthesia. Traditional practices simply place animals on ordinary lab tables to await awakening, lacking care equipment designed specifically for their unique physiological state. This increases the risks of airway obstruction and hypothermia, affecting the reliability of experimental results. With rising research standards, there is an urgent need for a specialized device to comprehensively care for anesthetized mice and rats, ensuring their safety and health, and improving the quality and stability of experimental data. Utility Model Content
[0003] To address the aforementioned technical problems, this utility model aims to provide a device for caring for laboratory animals after respiratory experiments, thereby ensuring the safety and health of the animals and improving the quality and stability of experimental data.
[0004] To achieve the above objectives, this utility model provides:
[0005] A device for caring for laboratory animals after respiratory experiments, comprising an inclined insulated nursing table, a support assembly, and an auxiliary breathing assembly;
[0006] The inclined heat-insulating nursing table includes a tabletop and an electric heating heat-insulating component, wherein the electric heating heat-insulating component is disposed on the tabletop;
[0007] The support component abuts against the inclined insulated nursing table to support the inclined insulated nursing table, and the support component can adjust the support angle to change the tilt angle of the inclined insulated nursing table.
[0008] The respiratory support assembly is located on the inclined insulated nursing table and is used to assist the breathing of experimental animals.
[0009] In a preferred embodiment, the support assembly consists of a base plate and a support rod. The upper end of the support rod abuts against the back of the tabletop. Multiple positioning holes are symmetrically distributed on opposite sides of the base plate. The lower end of the support rod is adapted to the positioning holes, and the lower end of the support rod can be connected to any one of the positioning holes.
[0010] As a preferred embodiment, the side of the tabletop closest to the base plate is hinged to the base plate.
[0011] In a preferred embodiment, the breathing aid consists of fixing pins and elastic cords. The fixing pins are located on opposite sides of the table surface and are used to fix the two ends of the elastic cords to the table surface.
[0012] As a preferred embodiment, the position and height of the fixing pin can be adjusted.
[0013] As a preferred embodiment, the electric heating insulation component is an electric heating insulation board, and the electric heating insulation board is equipped with a water circulation insulation system.
[0014] As a preferred embodiment, the water circulation insulation system consists of water circulation pipes disposed inside the electric heating insulation board, and the water circulation pipes are connected to a temperature-controlled water tank outside the electric heating insulation board.
[0015] As a preferred embodiment, the top of the work surface is equipped with an information recording board for researchers to record experimental information.
[0016] As a preferred embodiment, the platform is at least partially hollow at the position corresponding to the head of the experimental animal.
[0017] As a preferred embodiment, the inclination angle of the inclined insulated nursing table is 5-70°.
[0018] Compared with the prior art, the present invention has the following advantages:
[0019] 1. Improved respiratory care: By combining the inclined design of the inclined heated nursing table with the elastic ropes of the auxiliary breathing components, experimental animals can breathe naturally with their mouths open under gravity, which effectively solves the problem of respiratory distress that may occur in anesthetized animals after experiments, reduces the risk of airway obstruction, and improves the survival rate and health status of animals.
[0020] 2. Precise body temperature maintenance: The electric heating plate is equipped with a water circulation insulation system, which can precisely control the temperature of the nursing table and avoid adverse effects caused by body temperature fluctuations during the recovery of experimental animals from anesthesia. This provides a stable recovery environment for the animals and helps their physiological functions to recover normally.
[0021] 3. Wide applicability: The adjustable design of the respiratory support component makes the device suitable for mice and rats of different sizes, enhancing the versatility and flexibility of the equipment and meeting the needs of various biomedical experiments.
[0022] 4. Simple and efficient operation: The entire device has a simple structure and is easy to operate. Experimenters can quickly get started, reducing tedious steps in the care process, improving work efficiency, and ensuring effective care for experimental animals. Attached Figure Description
[0023] Figure 1 This is a schematic diagram of the device of this utility model for caring for experimental animals after respiratory experiments.
[0024] The attached figures are labeled as follows:
[0025] 1-Support rod; 2-Base plate; 3-Tabletop; 4-Electric heating and insulation components;
[0026] 5-Positioning socket; 6-Elastic cord; 7-Fixing nail; 8-Information recording board. Detailed Implementation
[0027] The embodiments of this utility model will be described in detail below. However, those skilled in the art should understand that the following embodiments are only for illustrating this utility model and should not be considered as limiting the scope of this utility model. Unless otherwise specified in the embodiments, conventional conditions or conditions recommended by the manufacturer shall apply. Reagents or instruments whose manufacturers are not specified are all conventional products that can be purchased commercially.
[0028] In the field of biomedical research, endotracheal intubation experiments in mice and rats are an important tool for many respiratory-related studies and the construction of disease models, playing a crucial role in areas such as studying the pathological mechanisms of lung diseases and evaluating drug efficacy. However, there are currently significant deficiencies in the care of mice and rats under anesthesia after these experiments.
[0029] In traditional experiments, after intubation, animals are typically simply placed on a standard lab table to await recovery, lacking specialized care equipment to address their unique physiological state and potential complications. During endotracheal intubation, the respiratory tract of mice and rats undergoes invasive manipulation, potentially affecting their respiratory function to varying degrees, leading to risks such as increased airway secretions, airway spasm, or local tissue damage. If proper care is not provided during the anesthesia recovery period, airway obstruction can easily occur, resulting in hypoxia or even death, severely impacting the reliability and validity of experimental results.
[0030] Furthermore, under anesthesia, laboratory animals are in a relatively vulnerable state regarding their thermoregulation and circulatory systems. Ordinary environments cannot effectively maintain stable body temperatures, easily leading to hypothermia, which affects their metabolism and physiological recovery, prolongs awakening time, and may cause a series of subsequent health problems, interfering with the accurate interpretation of experimental results. Simultaneously, the lack of proper fixation and adjustment devices for animal posture can exacerbate respiratory distress or cause compression injuries to other parts of the body due to improper positioning.
[0031] With the increasing demands for experimental precision and animal welfare in biomedical research, there is an urgent need for a specialized device that can comprehensively and effectively care for anesthetized animals after tracheal intubation experiments in mice and rats, in order to ensure the safety and health of experimental animals and improve the quality and stability of experimental data.
[0032] Therefore, as Figure 1 As shown, this utility model proposes a device for caring for laboratory animals after respiratory experiments, including an inclined insulated nursing table, a support component, and an auxiliary breathing component. The inclined insulated nursing table is responsible for supporting the laboratory animal and keeping it warm. The inclined insulated nursing table includes a table surface 3 and an electric heating component 4, which is disposed on the table surface 3. The support component abuts against the inclined insulated nursing table to support it, and the support component can adjust the support angle to change the tilt angle of the inclined insulated nursing table. The auxiliary breathing component is disposed on the inclined insulated nursing table to assist the laboratory animal's breathing and maintain its respiratory patency.
[0033] This invention provides a device for caring for laboratory animals after respiratory experiments. By combining an inclined, insulated nursing table and an auxiliary respiratory component, it achieves effective support, insulation, and respiratory management for the animals. The adjustable tilt angle of the nursing table and the auxiliary respiratory component support smooth breathing, ensuring the animals maintain a suitable position during anesthesia recovery and promoting unobstructed breathing. Simultaneously, a precisely temperature-controlled electrothermal insulation component maintains stable body temperature, thereby improving animal survival rates and health status, and ensuring the quality and stability of experimental data. This device is simple in structure, easy to operate, and applicable to mice and rats of different sizes, meeting the high standards required for biomedical experiments.
[0034] In one embodiment, the support assembly consists of a base plate 2 and a support rod 1. The upper end of the support rod 1 abuts against the back of the table surface 3. A plurality of positioning holes 5 are symmetrically distributed on opposite sides of the base plate 2. The lower end of the support rod 1 is adapted to the positioning holes 5, and the lower end of the support rod 1 can be connected to any one of the positioning holes 5.
[0035] In the above embodiments, by placing the support rod 1 in any of the positioning holes 5 (i.e., positioning holes 5 at different positions), the tilt angle of the inclined warming nursing table can be adjusted to ensure that experimental animals of different sizes can be in a suitable position. This is beneficial for the experimental animals to breathe smoothly and also facilitates observation and operation by the experimental personnel.
[0036] In another embodiment, the upper end of the support rod 1 can also be hinged to the back of the table surface 3. In this way, in addition to providing abutment support to the table surface 3, the support rod 1 can also be rotated to easily insert the lower end of the support rod 1 into any positioning hole 5, thereby facilitating the adjustment of the tilt angle of the inclined heat preservation nursing table.
[0037] In one embodiment, the platform 3 is hinged to the base plate 2 on the side closest to it. Adjusting the tilt angle of the nursing table is easy by simply rotating the platform 3 relative to the base plate 2. This hinged connection, combined with the symmetrically distributed positioning holes 5 on both sides of the base plate 2 and the lower end of the support rod 1, allows researchers to place the support rod 1 into different positioning holes 5 as needed, thereby adjusting the tilt of the inclined warming nursing table. This design ensures that experimental animals of different sizes can be positioned optimally, promoting smooth breathing and facilitating observation and manipulation by researchers. Furthermore, a suitable tilt angle can utilize gravity to help maintain the openness of the animal's airway, reducing the risk of airway obstruction.
[0038] In one embodiment, the assisted breathing assembly consists of fixing pins 7 and elastic cords 6. The fixing pins 7 are located on opposite sides of the table surface 3, and are used to fix both ends of the elastic cords 6 to the table surface 3. When the experimenter fixes the experimental animal, different sets of elastic cords 6 (i.e., different types of elastic cords 6, which may be of different thicknesses, etc.) can be selected according to the size of the animal to fix it. After gently lifting the elastic cords, the head of the experimental animal is positioned above the electric heating and insulation component 4, and its upper teeth are hooked onto the elastic cords 6. Utilizing the tilt angle of the inclined heating and insulation table and the animal's own weight, the animal's mouth naturally opens, which helps maintain its airway patency and promotes breathing.
[0039] In the above embodiments, the fixation nail 7 and the elastic rope 6 are important components of the respiratory support assembly, which can ensure that the experimental animals can maintain an appropriate body position during anesthesia recovery, thereby maintaining the patency of the airway.
[0040] In one embodiment, the position and height of the fixation pin 7 are adjustable to accommodate experimental animals of different sizes, providing optimal support and fixation. For example, the fixation pin 7 can be designed to be installed or moved at different locations on the table 3, allowing adjustment of the starting point of the elastic cord according to the size of the experimental animal, ensuring appropriate fixation for mice and rats of different sizes. Alternatively, the height of the fixation pin 7 can be adjusted to allow vertical movement to accommodate differences in head height between mice and rats of different sizes, ensuring that when the upper teeth of the mouse or rat are hooked onto the elastic cord, its mouth can open naturally, maintaining a clear airway.
[0041] In the above embodiments, by adjusting the position and height of the fixation pin 7, the nursing device can be applied to laboratory animals of different sizes, from mice to rats, improving the device's versatility and flexibility. Furthermore, the precise adjustment of the elastic cord's position and tension allows mice and rats to maintain the most suitable position during anesthesia recovery, utilizing gravity to help their mouths open naturally, promoting unobstructed breathing and reducing the risk of airway obstruction. Appropriate adjustments to the fixation position also prevent excessive stretching of oral tissues or unnecessary pressure, contributing to improved animal comfort and reducing the risk of injury due to improper fixation. Simultaneously, the easily adjustable design allows researchers to quickly and accurately fix the animals, reducing preparation time and improving experimental efficiency.
[0042] In one embodiment, the electric heating insulation component 4 is an electric heating insulation board, which is equipped with a water circulation insulation system. After being powered on, the electric heating insulation board can ensure that the temperature of the front area of the table surface 3 (i.e., the area in contact with the experimental animal) is suitable and uniform, effectively maintaining the body temperature of the experimental animal under anesthesia and preventing physiological dysfunction due to hypothermia.
[0043] In the above embodiments, because experimental animals' thermoregulation ability decreases under anesthesia, they are prone to hypothermia. This not only affects their metabolism and physiological function recovery but may also prolong awakening time and cause a series of health problems, thereby interfering with the accuracy of experimental results. When the electric heating plate is powered on, it can provide uniform and stable heat to the experimental animals, thus effectively preventing physiological dysfunction caused by hypothermia.
[0044] In one embodiment, the water circulation and heating system comprises water circulation pipes disposed inside the electric heating insulation plate, and the water circulation pipes are connected to a temperature-controlled water tank outside the electric heating insulation plate. By configuring the water circulation and heating system and connecting the internal water circulation pipes of the system to the external temperature-controlled water tank, precise control of the temperature of the nursing table can be achieved, further ensuring the comfort and safety of experimental animals during anesthesia recovery, and improving the quality and stability of experimental data.
[0045] In the above embodiments, the water circulation insulation system, connected to an external temperature-controlled water tank, enables precise control of the treatment table temperature. Specifically, the electric heating insulation panel contains water circulation pipes that allow water flow and regulate temperature through heating or cooling. The temperature-controlled water tank maintains the water temperature at a set value and is equipped with heating elements and / or cooling devices, as well as temperature sensors to monitor the water temperature. The control system within the water tank automatically adjusts the heating or cooling functions based on data from the built-in or external temperature sensors to maintain a constant water temperature. This ensures a stable water temperature flowing through the pipes inside the electric heating insulation panel, resulting in a uniform and adjustable surface temperature of the panel. Researchers can set target temperatures for the temperature-controlled water tank (e.g., 37°C for mice and 38°C for rats in this embodiment) to achieve precise responses to different experimental needs.
[0046] In one embodiment, the top of the work surface 3 is equipped with an information recording board 8, which can be used by researchers to record experimental information. The information recording board 8 can be a smooth whiteboard, on which researchers can use whiteboard markers to number different experimental animals, record their status, and other important information. By recording the status of each experimental animal on the whiteboard, researchers can more easily track the health status and recovery progress of each animal, helping to improve management efficiency during the experiment. Furthermore, since whiteboard marker ink can be easily wiped clean with an eraser or a damp wipe, researchers can update the records promptly based on changes in the animal's status, maintaining the accuracy and timeliness of the information. Moreover, the recording function on the smooth whiteboard is particularly important when handling multiple experimental animals simultaneously, as it helps researchers better organize workflows and ensures that each animal receives appropriate attention and care.
[0047] In one embodiment, the platform 3 is at least partially hollow at the position corresponding to the head of the experimental animal, to facilitate operation by the experimenter, especially to provide convenience when fixing the head of the experimental animal.
[0048] In the above embodiments, when the tabletop 3 is used in conjunction with the elastic cord 6, the experimenter can easily lift the head of the experimental animal from the hollow part on the back of the tabletop 3 and hook its upper teeth onto the elastic cord. This design makes the animal fixation process simpler and faster, reducing unnecessary interference and stress on the animal. The hollow structure also provides the experimenter with more operating space and angle selection, which is beneficial for adjusting the head position without moving or with minimal movement of the animal's body, helping to maintain the animal's comfortable and stable position on the care table. In addition, this design also takes into account allowing the experimenter to observe the animal's condition from different angles, especially the condition of key areas such as the oral cavity and nasal cavity, making it easier to detect and deal with potential problems in a timely manner, such as whether the airway is clear.
[0049] In one embodiment, the inclined heated nursing table has an inclination angle of 5-70° to ensure that experimental animals of different sizes (mice and rats) are in the most suitable position, promoting smooth breathing and facilitating observation and operation by researchers. An appropriate inclination angle utilizes gravity to help the experimental animals' mouths open naturally, helping to maintain airway patency and reducing the risk of airway obstruction due to anesthesia. Different experimental animals vary greatly in size, from mice to rats, and their requirements for the optimal inclination angle also differ. A range of 5-70° can meet the needs of these different sizes of mice and rats, ensuring that each animal receives the most suitable support. For smaller mice, a gentler angle is needed to maintain smooth breathing in their natural posture and avoid discomfort or damage caused by excessive stretching of oral tissues. Therefore, for mice, a lower inclination angle can be selected, such as close to 5-15°, to ensure comfort while effectively supporting breathing. In contrast, larger rats may require a slightly larger inclination angle to help keep their airways open, as their greater body weight means a flatter angle may not be sufficient to prevent airway compression. Therefore, for rats, a tilt angle between 15-70° is more suitable to better utilize gravity to assist mouth breathing and reduce the risk of airway obstruction.
[0050] Example 1
[0051] Post-tracheal intubation care in mice
[0052] The experimental steps are as follows:
[0053] 1. Preparation:
[0054] A healthy mouse weighing approximately 20g was selected, and tracheal intubation was performed according to standard experimental procedures.
[0055] Prepare the anesthesia animal care device after the rat and mouse tracheal intubation experiment of this utility model, connect the water circulation and heat preservation system to the temperature control water tank, set the temperature to 37℃, ensure that the water in the water circulation pipe flows normally, so that the inclined heat preservation care table reaches the preset temperature.
[0056] 2. Nursing procedures:
[0057] After anesthetizing, the mice are gently placed on an inclined, warming care table, allowing their bodies to lie naturally along the incline.
[0058] Select the appropriate fixing pins and the appropriate type of elastic cord. Gently lift the elastic cord so that the mouse's head is above the electric heating plate. Lift the mouse's head from the hollow part of the back of the table and hook its upper teeth onto the elastic cord. Adjust the position of the support rod so that the inclined surface of the nursing table is at a suitable tilt angle, ensuring that the mouse is in a suitable position and its mouth is open to a suitable degree, so as not to overstretch the oral tissue and to ensure that the airway is unobstructed.
[0059] 3. Observation and Recording:
[0060] During the care process, the researchers observed the mice's respiratory rate, heart rate, and oral and nasal secretions every 5 minutes and recorded the findings in detail on a whiteboard.
[0061] After 30 minutes of care, the mouse's breathing gradually stabilized, with the respiratory rate decreasing from approximately 120 breaths per minute to approximately 80 breaths per minute, and its heartbeat also stabilized. There was no obvious obstruction of secretions in the mouse's mouth and nasal cavity, and its physical condition was good.
[0062] 4. Result Evaluation:
[0063] After one hour of continuous care, the mice successfully awoke and moved freely, without exhibiting any adverse reactions due to airway obstruction or hypothermia. This indicates that the nursing device can effectively meet the nursing needs of mice after tracheal intubation experiments and ensure their healthy recovery.
[0064] Example 2
[0065] Nursing care after rat tracheal intubation experiment
[0066] 1. Preparation:
[0067] An adult rat weighing approximately 200g was selected to perform a tracheal intubation experiment.
[0068] Check the water circulation and heating system of the nursing device, set the temperature to 38℃, and ensure that the temperature of the nursing table is suitable.
[0069] 2. Nursing procedures:
[0070] The rat was placed on an inclined, heated nursing table, and its position was adjusted.
[0071] Because the rats are relatively large, a thicker elastic rope was used to hook the rat's upper teeth onto the rope. The support rod was adjusted to a suitable position according to the rat's size to help the rat breathe through its mouth.
[0072] 3. Observation and Recording:
[0073] The rats' physiological indicators, including respiration, heart rate, and body temperature, were observed every 10 minutes.
[0074] During the nursing process, it was found that the rats' breathing was initially rapid, with a respiratory rate of about 60 times per minute. After 20 minutes of nursing, the respiratory rate gradually decreased to about 40 times per minute, and the heart rate also stabilized from about 200 beats per minute to about 160 beats per minute.
[0075] 4. Result Evaluation:
[0076] After 1.5 hours of care, the rats awoke, their limbs moved strongly, and they were able to eat and drink normally. Throughout the care process, the rats did not experience airway obstruction or abnormal body temperature, fully verifying the applicability and effectiveness of the care device for rats and mice of different sizes.
[0077] The above description is only a preferred embodiment of the present utility model, but the protection scope of the present utility model is not limited thereto. Any equivalent substitutions or changes made by those skilled in the art within the technical scope disclosed in the present utility model, based on the technical solution and concept of the present utility model, should be covered within the protection scope of the present utility model.
Claims
1. A device for caring for laboratory animals after respiratory experiments, characterized in that, Includes inclined heated nursing table, support components and assisted breathing components; The inclined heat preservation nursing table includes a tabletop (3) and an electric heating heat preservation component (4), which is disposed on the tabletop (3); The support component abuts against the inclined insulated nursing table to support the inclined insulated nursing table, and the support component can adjust the support angle to change the tilt angle of the inclined insulated nursing table. The respiratory support assembly is located on the inclined insulated nursing table and is used to assist the breathing of experimental animals.
2. The device for caring for laboratory animals after respiratory experiments according to claim 1, characterized in that, The support assembly consists of a base plate (2) and a support rod (1). The upper end of the support rod (1) abuts against the back of the table surface (3). Multiple positioning holes (5) are symmetrically distributed on opposite sides of the base plate (2). The lower end of the support rod (1) is adapted to the positioning hole (5), and the lower end of the support rod (1) can be connected to any one of the positioning holes (5).
3. The device for caring for laboratory animals after respiratory experiments according to claim 2, characterized in that, The side of the tabletop (3) closest to the base plate (2) is hinged to the base plate (2).
4. The apparatus for caring for laboratory animals after respiratory experiments according to claim 1, 2, or 3, characterized in that, The assisted breathing assembly consists of a fixing pin (7) and an elastic cord (6). The fixing pin (7) is located on opposite sides of the table surface (3), and the fixing pin (7) is used to fix the two ends of the elastic cord (6) to the table surface (3).
5. The device for caring for laboratory animals after respiratory experiments according to claim 4, characterized in that, The position and height of the fixing pin (7) can be adjusted.
6. The apparatus for caring for laboratory animals after respiratory experiments according to claim 1, 2, or 3, characterized in that, The electric heating insulation component (4) is an electric heating insulation board, and the electric heating insulation board is equipped with a water circulation insulation system.
7. The apparatus for caring for laboratory animals after respiratory experiments according to claim 6, characterized in that, The water circulation insulation system consists of water circulation pipes installed inside the electric heating insulation board, and the water circulation pipes are connected to a temperature-controlled water tank outside the electric heating insulation board.
8. The apparatus for caring for laboratory animals after respiratory experiments according to claim 1, 2, or 3, characterized in that, The top of the tabletop (3) is provided with an information recording board (8) for experimental personnel to record experimental information.
9. The apparatus for caring for laboratory animals after respiratory experiments according to claim 1, 2, or 3, characterized in that, The platform (3) is at least partially hollow at the position corresponding to the head of the experimental animal.
10. The apparatus for caring for laboratory animals after respiratory experiments according to claim 1, 2, or 3, characterized in that, The inclination angle of the inclined insulated nursing table is 5-70°.