Multi-stage membrane separation type tilpotide purification device

By employing a multi-stage membrane separation structure and dynamic filtration technology, the problem of filter cake formation in the telpoide purification device was solved, achieving a highly efficient filtration effect.

CN224207776UActive Publication Date: 2026-05-08SHANGHAI YUYUN PHARMACEUTICAL EQUIPMENT CO LTD
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
SHANGHAI YUYUN PHARMACEUTICAL EQUIPMENT CO LTD
Filing Date
2025-06-04
Publication Date
2026-05-08

AI Technical Summary

Technical Problem

Existing telpoide purification devices are prone to forming a filter cake layer during the filtration process, which leads to increased filtration resistance and decreased filtration efficiency.

Method used

It adopts a multi-stage membrane separation structure, and drives the coarse filter membrane and the fine filter membrane to rotate synchronously through the drive component to achieve dynamic filtration, avoid impurities from accumulating on the membrane surface, and intercept impurities in stages by combining coarse filtration and fine filtration.

Benefits of technology

It effectively reduces filtration resistance, increases liquid flow rate, improves overall filtration efficiency, and ensures a smooth and efficient filtration process.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model relates to the technical field of purification devices, in particular to a multi-stage membrane separation type tiall peptide purification device. According to the technical scheme, the device comprises a barrel, and the outer wall of the barrel is communicated with a discharging pipe used for discharging materials; a first purification assembly used for coarse filtration of the tirpotide is arranged in the cylinder, and the outer wall of the first purification assembly is sleeved with a second purification assembly used for fine filtration of the tirpotide; the driving assembly is fixedly mounted on the outer wall of the cylinder and is used for driving the first purification assembly and the second purification assembly to rotate. According to the utility model, the coarse filtering membrane and the fine filtering membrane can rotate synchronously, the dynamic filtering effect is realized, impurities are prevented from staying and accumulating on the surfaces of the membranes for a long time to form a filter cake layer, the filtering resistance is effectively reduced, the speed of liquid passing through the filtering membranes is improved, and the overall filtering efficiency is further improved.
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Description

Technical Field

[0001] This utility model relates to the field of purification device technology, and in particular to a multi-stage membrane separation type telpoide purification device. Background Technology

[0002] In the pharmaceutical field, telpolide is a drug with significant clinical value. Its purification process plays a crucial role in the drug's quality and efficacy. Effective purification removes impurities, improves the purity and activity of telpolide, and ensures the drug's safety and efficacy. Existing telpolide purification devices use fixed multi-layer filter membranes for filtration. While these can filter impurities from telpolide, they also cause impurities to accumulate on the membrane surfaces as they pass through, forming a filter cake layer that hinders material flow. As filtration time increases, the filter cake layer thickens, significantly increasing filtration resistance and drastically reducing the liquid's flow rate through the membrane, resulting in a decrease in overall filtration efficiency. Therefore, this invention proposes a multi-stage membrane separation telpolide purification device. Utility Model Content

[0003] The purpose of this invention is to address the problems existing in the background technology by proposing a multi-stage membrane separation type telpoide purification device.

[0004] The technical solution of this utility model is as follows: a multi-stage membrane separation type telpoide purification device, comprising: a cylinder, wherein a discharge pipe for material discharge is connected to the outer wall of the cylinder; a first purification component for coarse filtration of telpoide is disposed inside the cylinder, and a second purification component for fine filtration of telpoide is sleeved on the outer wall of the first purification component; and a drive component fixedly installed on the outer wall of the cylinder for driving the first purification component and the second purification component to rotate.

[0005] Optionally, the first purification component includes a first fixing plate and a second fixing plate disposed inside the cylinder. A plurality of first fixing rods are fixedly disposed between the first fixing plate and the second fixing plate. A coarse filter membrane is sleeved between the first fixing rods. The two ends of the coarse filter membrane are respectively sealed and connected to the first fixing plate and the second fixing plate. A first connecting cylinder is disposed in communication with one side of the first fixing plate. The first connecting cylinder passes through the cylinder and extends to the outside, where a first transmission wheel is fixedly sleeved. A sleeve block is fixedly disposed on one side of the second fixing plate.

[0006] Optionally, the second purification component includes a third baffle and a fourth baffle disposed inside the cylinder. The third baffle is sleeved with the first connecting cylinder, and the fourth baffle is sleeved with the connecting block. A plurality of second fixing rods are fixedly disposed between the third baffle and the fourth baffle. A fine filter membrane is sleeved between the second fixing rods. The two ends of the fine filter membrane are respectively sealed to the third baffle and the fourth baffle. A second connecting cylinder is fixedly disposed on one side of the fourth baffle. One end of the second connecting cylinder passes through the cylinder and extends to the outside, where a second transmission wheel is fixedly sleeved.

[0007] Optionally, the drive assembly includes a bidirectional motor fixedly installed on the outer wall of the cylinder. The output end of the bidirectional motor is fixedly connected to a transmission rod, and one end of the transmission rod is fixedly connected to a third transmission wheel. A transmission belt is provided between the third transmission wheel and the first and second transmission wheels respectively.

[0008] Optionally, a feed pipe is sleeved inside the first connecting cylinder. One end of the feed pipe extends into the interior of the first purification component, and the other end of the feed pipe is connected to a feed hopper. A fixing collar is fixedly sleeved on the outer wall of the feed pipe, and multiple support rods are fixedly connected to the outer wall of the fixing collar. One end of each support rod is fixedly connected to the cylinder body.

[0009] Optionally, a bracket is fixedly connected to the outer wall of the cylinder.

[0010] Optionally, a door is hinged to the outer wall of the cylinder.

[0011] Optionally, a rotating plug is threaded through one side of the second fixing plate and the fourth baffle.

[0012] In summary, this application includes at least one of the following beneficial technical effects:

[0013] This invention uses a bidirectional motor, transmission rod, third transmission wheel and transmission belt structure in the drive assembly to drive the first transmission wheel of the first purification assembly and the second transmission wheel of the second purification assembly to rotate, so that the coarse filtration membrane and the fine filtration membrane rotate synchronously, to achieve dynamic filtration effect, avoid impurities from staying and accumulating on the membrane surface for a long time to form a filter cake layer, effectively reduce filtration resistance, increase the speed of liquid passing through the filtration membrane, and thus improve the overall filtration efficiency.

[0014] Furthermore, this utility model utilizes a multi-stage separation structure with the first purification component and the second purification component interlocked. It first performs preliminary filtration through a coarse filtration membrane, and then further purifies the material through a fine filtration membrane. This intercepts impurities of different particle sizes in stages, reducing the amount of impurities retained by a single-stage filtration membrane, slowing down the formation rate of the filter cake layer, optimizing the material flow path, and ensuring a smooth and efficient filtration process. Attached Figure Description

[0015] Figure 1This is a schematic diagram of a multi-stage membrane separation type telpoide purification device;

[0016] Figure 2 for Figure 1 A partial diagram of the split structure;

[0017] Figure 3 for Figure 2 Schematic diagram of the internal cross-sectional structure of the middle cylinder;

[0018] Figure 4 for Figure 2 A schematic diagram showing the disassembled structure of the first and second purification components;

[0019] Figure 5 for Figure 4 This illustrates another structural intention from a different perspective.

[0020] Figure label:

[0021] 1. Cylinder body; 2. Discharge pipe;

[0022] 3. First purification component; 31. First fixing plate; 32. Second fixing plate; 33. First fixing rod; 34. Coarse filter membrane; 35. First connecting cylinder; 36. First transmission wheel; 37. Sleeve block;

[0023] 4. Second purification component; 41. Third baffle; 42. Fourth baffle; 43. Second fixing rod; 44. Fine filter membrane; 45. Second connecting cylinder; 46. Second transmission wheel;

[0024] 5. Drive assembly; 51. Bidirectional motor; 52. Transmission rod; 53. Third transmission wheel; 54. Transmission belt;

[0025] 6. Feed pipe; 7. Feed hopper; 8. Fixing collar; 9. Support rod; 10. Bracket; 11. Gate; 12. Rotary plug. Detailed Implementation

[0026] The technical solution of this utility model will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are some embodiments of this utility model, but not all embodiments.

[0027] The components of the present invention embodiments described and shown in the accompanying drawings can typically be arranged and designed in a variety of different configurations. Therefore, the following detailed description of the embodiments of the present invention provided in the drawings is not intended to limit the scope of the claimed invention, but merely to illustrate selected embodiments of the invention.

[0028] Based on the embodiments of this utility model, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of this utility model.

[0029] In the description of this utility model, it should be noted that the terms "center," "upper," "lower," "left," "right," "vertical," "horizontal," "inner," and "outer," etc., indicating the orientation or positional relationship, are based on the orientation or positional relationship shown in the accompanying drawings and are only for the convenience of describing this utility model and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation, and therefore should not be construed as a limitation of this utility model. Furthermore, the terms "first," "second," and "third" are used for descriptive purposes only and should not be construed as indicating or implying relative importance.

[0030] In the description of this utility model, it should be noted that, unless otherwise explicitly specified and limited, the terms "installation," "connection," and "joining" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral connection; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; and they can refer to the internal connection of two components. Those skilled in the art can understand the specific meaning of the above terms in this utility model based on the specific circumstances.

[0031] Example

[0032] like Figure 1 and Figure 2 As shown, the multi-stage membrane separation type telpoide purification device proposed in this utility model includes: a cylinder 1, a support 10 fixedly connected to the outer wall of the cylinder 1 to provide stable support for the cylinder 1, a cylinder door 11 hinged to the outer wall of the cylinder 1, and a sealing ring provided at the connection between the cylinder 1 and the cylinder door 11 to ensure the sealing of the cylinder 1 and prevent the internal liquid from flowing out, while facilitating the cleaning of the first purification component 3 and the second purification component 4. A discharge pipe 2 for material discharge is connected to the outer wall of the cylinder 1 to facilitate the discharge of the material filtered by the cylinder 1.

[0033] like Figure 1 Figure 3 , Figure 4 and Figure 5As shown, the interior of the cylindrical body 1 is equipped with a first purification component 3 for coarse filtration of telpoide. The first purification component 3 includes a first fixing plate 31 and a second fixing plate 32 disposed inside the cylindrical body 1, and the first fixing plate 31 and the second fixing plate 32 are symmetrically arranged. A plurality of first fixing rods 33 are fixedly disposed between the first fixing plate 31 and the second fixing plate 32, and the plurality of first fixing rods 33 are arranged in a circumferential array. A coarse filtration membrane 34 is sleeved between the first fixing rods 33, which can form the coarse filtration membrane 34 into a cylindrical shape. The two ends of the coarse filtration membrane 34 are respectively connected to the first fixing plate 31 and the second fixing plate 32. The plate 32 is sealed and connected, and a sealing ring can be used at the joint to prevent liquid from flowing out from both sides of the coarse filter membrane 34. A first connecting cylinder 35 is connected to one side of the first fixing plate 31. The first connecting cylinder 35 passes through the cylinder body 1 and extends to the outside to be fixedly connected to the first transmission wheel 36. A bearing is provided at the penetration point between the first connecting cylinder 35 and the cylinder body 1, which enables the first connecting cylinder 35 to rotate stably and facilitates the transfer of material through the cylinder body 1 to the inside of the coarse filter membrane 34. A sleeve block 37 is fixedly provided on one side of the second fixing plate 32, which can limit the other end of the coarse filter membrane 34 and ensure the stability of rotation.

[0034] Furthermore, a second purification component 4 for fine filtration of telpoide is sleeved on the outer wall of the first purification component 3. The second purification component 4 includes a third baffle 41 and a fourth baffle 42 disposed inside the cylinder 1, and the third baffle 41 and the fourth baffle 42 are symmetrically arranged. The third baffle 41 is fixedly sleeved with the first connecting cylinder 35, and the fourth baffle 42 is fixedly sleeved with the sleeve block 37. A plurality of second fixing rods 43 are fixedly arranged between the third baffle 41 and the fourth baffle 42, and the plurality of second fixing rods 43 are arranged in a circumferential array. A fine filter membrane 44 is sleeved between 43, which enables the fine filter membrane 44 to form a cylindrical shape. The two ends of the fine filter membrane 44 are respectively sealed and connected to the third baffle 41 and the fourth baffle 42, and a sealing ring can be used at the sleeve to prevent liquid from flowing out from both sides of the fine filter membrane 44. A second connecting cylinder 45 is fixedly provided on one side of the fourth baffle 42. One end of the second connecting cylinder 45 passes through the cylinder body 1 and extends to the outside, where a second transmission wheel 46 is fixedly sleeved. A bearing is provided at the sleeve of the second connecting cylinder 45 and the cylinder body 1 to ensure the stability of the rotation of the fine filter membrane 44.

[0035] like Figure 1As shown, a drive assembly 5 for driving the first purification component 3 and the second purification component 4 to rotate is fixedly installed on the outer wall of the cylinder 1. The drive assembly 5 includes a bidirectional motor 51 fixedly installed on the outer wall of the cylinder 1. A transmission rod 52 is fixedly connected to the output end of the bidirectional motor 51, which can drive the transmission rod 52 to rotate simultaneously. A third transmission wheel 53 is fixedly connected to one end of the transmission rod 52, which can drive the third transmission wheel 53 to rotate. A transmission belt 54 is provided between the third transmission wheel 53 and the first transmission wheel 36 and the second transmission wheel 46 respectively, so that the third transmission wheel 53 drives the first transmission wheel 36 and the second transmission wheel 46 to rotate simultaneously through the transmission belt 54.

[0036] Furthermore, a feed pipe 6 is fitted inside the first connecting cylinder 35. One end of the feed pipe 6 extends into the interior of the first purification component 3, facilitating the flow of material into the interior of the coarse filtration membrane 34. The other end of the feed pipe 6 is connected to a feed hopper 7, which facilitates the addition of material into the feed pipe 6. A fixing collar 8 is fixedly fitted onto the outer wall of the feed pipe 6. Multiple support rods 9 are fixedly connected to the outer wall of the fixing collar 8. One end of the support rod 9 is fixedly connected to the cylinder 1, which can stably limit and fix the feed pipe 6 and the feed hopper 7.

[0037] A rotating plug 12 is threaded through one side of the second fixing plate 32 and the fourth baffle 42.

[0038] The working principle of this embodiment is as follows: First, the telpoeptide material to be purified is added into the feed hopper 7. The telpoeptide material enters the feed pipe 6 through the feed hopper 7 and is transported to the first purification component 3 through the feed pipe 6.

[0039] At this time, the bidirectional motor 51 in the drive assembly 5 starts, and the output end of the bidirectional motor 51 drives the transmission rod 52 to rotate, which in turn causes the third transmission wheel 53, which is fixedly connected to one end of the transmission rod 52, to rotate. Under the action of the transmission belt 54, the first transmission wheel 36 of the first purification assembly 3 and the second transmission wheel 46 of the second purification assembly 4 are driven, so that the coarse filtration membrane 34 and the fine filtration membrane 44 rotate synchronously.

[0040] During the rotation process, the telpoeptide material first comes into contact with the coarse filter membrane 34, which performs preliminary filtration, intercepting larger particle sizes of impurities. Because the coarse filter membrane 34 is rotating, impurities are unlikely to remain and accumulate on the membrane surface for a long time, avoiding the rapid formation of a filter cake layer, reducing filtration resistance, and allowing the liquid in the material to pass through the coarse filter membrane 34 relatively smoothly.

[0041] The material after coarse filtration enters the second purification component 4, where a fine filtration membrane 44 further purifies it, intercepting impurities with smaller particle sizes. Similarly, the rotation of the fine filtration membrane 44 effectively prevents impurity accumulation, ensuring high filtration efficiency.

[0042] During cleaning, the cylinder door 11 is opened, and the rotating plug 12 on one side of the second fixed plate 32 and the fourth baffle 42 is rotated open to remove impurities from the coarse filter membrane 34 and the fine filter membrane 44.

[0043] The above specific embodiments are merely optional embodiments of this utility model. Based on the technical solution of this utility model and the relevant teachings of the above embodiments, those skilled in the art can make various alternative improvements and combinations to the above specific embodiments.

Claims

1. A multi-stage membrane separation type telpoide purification device, characterized in that, include: The outer wall of the cylinder (1) is connected to a discharge pipe (2) for material discharge; A first purification component (3) for coarse filtration of telpoeptide is provided inside the cylinder (1), and a second purification component (4) for fine filtration of telpoeptide is attached to the outer wall of the first purification component (3). A drive assembly (5) is fixedly installed on the outer wall of the cylinder (1) to drive the first purification assembly (3) and the second purification assembly (4) to rotate.

2. The multi-stage membrane separation type telpoide purification device according to claim 1, characterized in that, The first purification component (3) includes a first fixing plate (31) and a second fixing plate (32) disposed inside the cylinder (1). A plurality of first fixing rods (33) are fixedly disposed between the first fixing plate (31) and the second fixing plate (32). A coarse filter membrane (34) is sleeved between the first fixing rods (33). The two ends of the coarse filter membrane (34) are respectively sealed and connected to the first fixing plate (31) and the second fixing plate (32). A first connecting cylinder (35) is connected to one side of the first fixing plate (31). The first connecting cylinder (35) penetrates the cylinder (1) and extends to the outside, where a first transmission wheel (36) is fixedly sleeved. A sleeve block (37) is fixedly disposed on one side of the second fixing plate (32).

3. The multi-stage membrane separation type telpoide purification device according to claim 2, characterized in that, The second purification component (4) includes a third baffle (41) and a fourth baffle (42) disposed inside the cylinder (1). The third baffle (41) is sleeved with the first connecting cylinder (35), and the fourth baffle (42) is sleeved with the connecting block (37). A plurality of second fixing rods (43) are fixedly disposed between the third baffle (41) and the fourth baffle (42). A fine filter membrane (44) is sleeved between the second fixing rods (43). The two ends of the fine filter membrane (44) are respectively sealed to the third baffle (41) and the fourth baffle (42). A second connecting cylinder (45) is fixedly disposed on one side of the fourth baffle (42). One end of the second connecting cylinder (45) penetrates the cylinder (1) and extends to the outside, where a second transmission wheel (46) is fixedly sleeved.

4. The multi-stage membrane separation type telpoide purification device according to claim 3, characterized in that, The drive assembly (5) includes a bidirectional motor (51) fixedly installed on the outer wall of the cylinder (1). The output end of the bidirectional motor (51) is fixedly connected to a transmission rod (52). One end of the transmission rod (52) is fixedly connected to a third transmission wheel (53). A transmission belt (54) is provided between the third transmission wheel (53) and the first transmission wheel (36) and the second transmission wheel (46) respectively.

5. The multi-stage membrane separation type telpoide purification device according to claim 3, characterized in that, The first connecting cylinder (35) is fitted with a feed pipe (6), one end of which extends into the interior of the first purification component (3), and the other end of which is connected to a feed hopper (7). A fixing ring (8) is fixedly fitted onto the outer wall of the feed pipe (6), and a plurality of support rods (9) are fixedly connected to the outer wall of the fixing ring (8). One end of the support rod (9) is fixedly connected to the cylinder (1).

6. The multi-stage membrane separation type telpoide purification device according to claim 1, characterized in that, The outer wall of the cylinder (1) is fixedly connected to a bracket (10).

7. The multi-stage membrane separation type telpoide purification device according to claim 1, characterized in that, The outer wall of the cylinder (1) is hinged with a cylinder door (11).

8. The multi-stage membrane separation type telpoide purification device according to claim 3, characterized in that, A rotating plug (12) is threaded through one side of the second fixing plate (32) and the fourth baffle (42).