Stem cell protection device
By introducing an independent liquid nitrogen freezing chamber and a shared retrieval chamber into the stem cell preservation device, combined with an arc-shaped opening and closing plate and a gear transmission system, the problem of sudden temperature changes inside the liquid nitrogen tank was solved, and the stable preservation of stem cells was achieved.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- CHONGQING BOKLONGCHUN BIOPHARMACEUTICAL CO LTD
- Filing Date
- 2025-04-17
- Publication Date
- 2026-05-15
AI Technical Summary
When existing stem cell preservation devices open the liquid nitrogen tank to retrieve cells, hot outside air rushes in rapidly, causing a sudden change in the temperature inside the liquid nitrogen tank, which affects the preservation quality of other stem cells.
A stem cell protection device was designed, comprising an independent liquid nitrogen freezing chamber and a shared retrieval chamber. Through an arc-shaped opening and closing plate and a gear transmission system, stem cells can be quickly retrieved, reducing the impact of temperature fluctuations on other stem cells.
This effectively reduces the impact of temperature fluctuations on stem cells, improves the overall preservation quality, and ensures the preservation stability of irrelevant stem cells.
Smart Images

Figure CN224234556U_ABST
Abstract
Description
Technical Field
[0001] This utility model belongs to the field of stem cell preservation technology, specifically relating to a stem cell protection device. Background Technology
[0002] Stem cell technology has become a breakthrough for mankind to overcome various intractable diseases in this century. Stem cells are not only used in the clinical treatment of various blood system, immune system and nervous system diseases, but are also beginning to be widely used in regenerative medicine, including the clinical treatment of various diseases such as tumors, heart disease, ophthalmological diseases, diabetes, orthopedic surgery, brain and spinal cord injuries.
[0003] As disclosed in Publication No. CN220044704U, this utility model discloses a human blood stem cell cooling and preservation device, including a protective shell, a liquid nitrogen tank, an extraction and storage assembly, and a cell storage box. The liquid nitrogen tank is located inside the protective shell. The extraction and storage assembly includes an extraction frame, a lifting rack, an external gear ring, a lifting bevel gear, and a lifting plate. The cell storage box is located on the extraction frame and inside the liquid nitrogen tank. The liquid nitrogen tank has an opening with a perforation through which the extraction frame passes. The lifting rack is located on the extraction frame. An external gear ring is rotatably mounted on the outside of the liquid nitrogen tank, and a lifting bevel gear is rotatably mounted on the liquid nitrogen tank. An upper bevel gear ring is located on the upper side of the external gear ring, and the upper bevel gear ring meshes with the lifting bevel gear. This utility model belongs to the field of stem cell preservation, specifically a human blood stem cell cooling and preservation device that reduces the contact between workers and the liquid nitrogen tank, improving safety and convenience.
[0004] Analysis revealed that this method exposes the entire interior of the liquid nitrogen tank during operation. When the tank lid is opened to retrieve cells, relatively hot outside air rapidly rushes into the tank. The interior of the liquid nitrogen tank is at a low temperature, typically around -196°C, while the outside temperature is generally between ten and several tens of degrees Celsius. This significant temperature difference causes heat to transfer from the outside into the tank. Since not all stem cells need to be retrieved, this can affect the preservation quality of other stem cells. Therefore, this method needs optimization and improvement to address these issues. Utility Model Content
[0005] To address the problems existing in the background technology, this utility model provides a stem cell protection device; it has an independent liquid nitrogen freezing chamber and a shared access chamber, which can effectively reduce the impact of temperature on stem cells.
[0006] This utility model provides a stem cell protection device, comprising an outer tank, an inner liquid nitrogen tank, and a plurality of refrigerated compartments evenly arranged within the liquid nitrogen tank. A retrieval compartment is provided between the outer tank and the liquid nitrogen tank. A stem cell protection component is provided in each refrigerated compartment of the liquid nitrogen tank. The stem cell protection component includes an opening corresponding to each refrigerated compartment, a groove at the opening, an arc-shaped opening and closing plate slidably connected within the groove, an arc-shaped gear rack fixedly connected to the arc-shaped opening and closing plate, and a gear rotatably connected within the groove. The gear meshes with the arc-shaped gear rack, and a transmission rod is fixedly connected to the gear. The opening extends out of the outer tank body. An L-shaped through hole is provided on the lower side of the opening. An L-shaped rod is slidably connected within the L-shaped through hole. One end of the L-shaped rod is fixedly connected to an arc-shaped opening and closing plate. The other end of the L-shaped rod is fixedly connected to an arc-shaped gear rack. A fixing plate is fixedly installed in the refrigerated compartment corresponding to the opening. A support plate is slidably connected within the fixing plate. A strip-shaped through hole is provided on the fixing plate. A gear rack is rotatably connected in the refrigerated compartment corresponding to the arc-shaped gear rack. A gear rack is fixedly connected to the gear rack. The gear rack meshes with the arc-shaped gear rack. A gear rack is fixedly connected to the support plate through the strip-shaped through hole. The gear rack meshes with the gear rack.
[0007] Furthermore, a cavity is provided between the outer tank and the liquid nitrogen tank.
[0008] Furthermore, the retrieval compartment is equipped with a gate.
[0009] Furthermore, the tray is slidably connected to the strip-shaped through hole.
[0010] Furthermore, a rotating disk is fixedly installed at one end of the transmission rod extending out of the outer tank, and the rotating disk is rotatably connected to the outer tank.
[0011] Furthermore, the number of refrigerated compartments is four.
[0012] The beneficial effects of this utility model are:
[0013] This invention, through structural improvements and optimizations, utilizes a ring-shaped refrigeration chamber and a centrally located retrieval chamber to effectively and quickly retrieve corresponding frozen stem cells. Furthermore, even significant temperature changes during retrieval do not affect unrelated stem cells, thus improving the overall quality of preservation. Attached Figure Description
[0014] Figure 1 This is a schematic diagram of a stem cell protection device according to the present invention.
[0015] Figure 2 This is a cross-sectional view of a stem cell protection device according to the present invention.
[0016] Figure 3 This is a schematic diagram of region A of a stem cell protection device according to the present invention.
[0017] Figure 4 This is a schematic diagram of region B of a stem cell protection device according to the present invention.
[0018] Figure 5 Structural breakdown of the arc-shaped opening and closing plate of the stem cell protection device of this utility model. Figure 1 .
[0019] Figure 6 Structural breakdown of the arc-shaped opening and closing plate of the stem cell protection device of this utility model. Figure 2 .
[0020] As shown in the figure:
[0021] 1. Outer tank, 2. Liquid nitrogen tank, 3. Refrigerated compartment, 4. Retrieval compartment, 5. Opening, 6. Groove, 7. Arc-shaped opening and closing plate, 8. Arc-shaped gear row one, 9. Gear one, 10. Transmission rod, 11. L-shaped through hole, 12. L-shaped rod, 13. Arc-shaped gear row two, 14. Fixing plate, 15. Support plate, 16. Strip-shaped through hole, 17. Gear two, 18. Gear three, 19. Gear row, 20. Cavity, 21. Gate, 22. Rotary disk. Detailed Implementation
[0022] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.
[0023] In the description of this utility model, it should be noted that, unless otherwise explicitly specified and limited, the terms "installed," "equipped with," and "connected," etc., should be interpreted broadly. For example, "connected" can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection or an indirect connection through an intermediate medium; it can be a connection within two components. Those skilled in the art can understand the specific meaning of the above terms in this utility model based on the specific circumstances.
[0024] Please refer to the accompanying diagrams in all instruction manuals:
[0025] A stem cell protection device includes an outer tank 1, a liquid nitrogen tank 2 inside the outer tank 1, and a plurality of refrigerated compartments 3 evenly arranged inside the liquid nitrogen tank 2, the number of refrigerated compartments 3 being 4; a retrieval compartment 4 is provided between the outer tank 1 and the liquid nitrogen tank 2, and stem cell protection components are provided in the liquid nitrogen tank 2 corresponding to the refrigerated compartments 3.
[0026] The stem cell protection component includes an opening 5 corresponding to the refrigerated compartment 3, a groove 6 at the opening 5, an arc-shaped opening and closing plate 7 slidably connected within the groove 6, an arc-shaped gear rack 8 fixedly connected to the arc-shaped opening and closing plate 7, a gear 9 rotatably connected within the groove 6, the gear 9 meshing with the arc-shaped gear rack 8, a transmission rod 10 fixedly connected to the gear 9, one end of the transmission rod 10 extending outside the outer tank 1, an L-shaped through hole 11 on the lower side of the opening 5, an L-shaped rod 12 slidably connected within the L-shaped through hole 11, one end of the L-shaped rod 12 engaging with the arc-shaped opening and closing plate. 7. Fixed connection: The other end of the L-shaped rod 12 is fixedly connected to the arc-shaped toothed rack 13. A fixed plate 14 is fixedly installed in the corresponding opening 5 inside the refrigerated compartment 3. A support plate 15 is slidably connected inside the fixed plate 14. A strip-shaped through hole 16 is provided on the fixed plate 14. A gear 17 is rotatably connected to the arc-shaped toothed rack 13 inside the refrigerated compartment 3. A gear 18 is fixedly connected to the gear 17. The gear 17 and the arc-shaped toothed rack 13 mesh with each other. A toothed rack 19 is fixedly connected to the support plate 15 through the strip-shaped through hole 16. The toothed rack 19 and the gear 18 mesh with each other.
[0027] As described above, when the control transmission rod 10 rotates, it will drive the gear 9 to rotate, which will drive the arc-shaped gear row 8 to move, and drive the arc-shaped opening and closing plate 7 to move into the groove 6. At the same time, the L-shaped rod 12 below the arc-shaped opening and closing plate 7 will drive the arc-shaped gear row 13 to move, which will drive the gear 17 to rotate. The gear 17 will drive the gear 18 to rotate, and the gear 18 will drive the gear row 19 to move. The gear row 19 will drive the tray 15 to move towards the opening 5, and the stem cells stored on the tray 15 can directly enter the retrieval chamber 4.
[0028] As a technical optimization of this utility model, a cavity 20 is provided between the outer tank 1 and the liquid nitrogen tank 2;
[0029] As can be seen from the above description, the cavity 20 can improve the thermal insulation performance of the outer tank 1 and the liquid nitrogen tank 2.
[0030] As a technical optimization of this utility model, the retrieval chamber 4 is provided with a gate 21;
[0031] As can be seen from the above description, the gate 21 can seal the retrieval compartment 4 and reduce energy leakage.
[0032] As a technical optimization of this utility model, the tray 15 is slidably connected to the strip-shaped through hole 16;
[0033] As can be seen from the above description, the sliding connection method makes the movement of the tray 15 more stable.
[0034] As a technical optimization of this utility model, a rotating disk 22 is fixedly installed at one end of the transmission rod 10 extending out of the outer tank 1, and the rotating disk 22 is rotatably connected to the outer tank 1.
[0035] As can be seen from the above description, by controlling the rotating disk 22, the internal structure can be controlled very quickly to achieve the extraction of the corresponding stem cells.
[0036] The working process of this utility model is as follows:
[0037] When the corresponding stem cells need to be retrieved, first rotate the corresponding rotating disk 22. When the transmission rod 10 rotates, it will drive the gear 9 to rotate, which will drive the arc-shaped gear row 8 to move, and drive the arc-shaped opening and closing plate 7 to move into the groove 6. At the same time, the L-shaped rod 12 below the arc-shaped opening and closing plate 7 will drive the arc-shaped gear row 13 to move, which will drive the gear 17 to rotate. The gear 17 will drive the gear 18 to rotate, and the gear 18 will drive the gear row 19 to move. The gear row 19 will drive the tray 15 to move towards the opening 5, and the stem cells stored on the tray 15 can directly enter the retrieval chamber 4. Then, open the valve 21 and take out the stem cells.
[0038] The present invention and its embodiments have been described above. This description is not restrictive, and the specific embodiments shown are only one of the embodiments of the present invention. The actual structure is not limited to this. In short, if a person skilled in the art is inspired by this description and designs a similar structure and embodiment without departing from the inventive spirit of the present invention, such design should fall within the protection scope of the present invention.
Claims
1. A stem cell protection device, comprising an outer canister, characterized in that: The outer tank contains a liquid nitrogen tank, which contains several evenly spaced refrigeration compartments. A retrieval compartment is located between the outer tank and the liquid nitrogen tank. A stem cell protection component is installed in each refrigeration compartment corresponding to the liquid nitrogen tank. The stem cell protection component includes an opening corresponding to each refrigeration compartment, with a groove at the opening. An arc-shaped opening / closing plate is slidably connected within the groove. An arc-shaped gear rack is fixedly connected to the arc-shaped opening / closing plate. A gear is rotatably connected within the groove, meshing with the arc-shaped gear rack. A transmission rod is fixedly connected to the gear, with one end extending out of the outer tank. The lower side of the opening is provided with an L-shaped through hole, and an L-shaped rod is slidably connected in the L-shaped through hole. One end of the L-shaped rod is fixedly connected to an arc-shaped opening and closing plate, and the other end of the L-shaped rod is fixedly connected to an arc-shaped gear rack two. A fixing plate is fixedly installed in the refrigerated compartment corresponding to the opening. A support plate is slidably connected in the fixing plate. A strip-shaped through hole is provided on the fixing plate. A gear two is rotatably connected in the refrigerated compartment corresponding to the arc-shaped gear rack two. A gear three is fixedly connected to the gear two. The gear two and the arc-shaped gear rack two mesh with each other. A gear rack is fixedly connected to the support plate through the strip-shaped through hole. The gear rack and the gear three mesh with each other.
2. The stem cell protection device according to claim 1, characterized in that: A cavity is provided between the outer tank and the liquid nitrogen tank.
3. The stem cell protection device according to claim 1, characterized in that: The retrieval compartment is equipped with a gate.
4. The stem cell protection device according to claim 1, characterized in that: The tray is slidably connected to the strip-shaped through hole.
5. A stem cell protection device according to claim 1, characterized in that: A rotating disk is fixedly installed at one end of the transmission rod that extends out of the outer tank, and the rotating disk is rotatably connected to the outer tank.
6. A stem cell protection device according to claim 1, characterized in that: The number of refrigerated compartments is 4.