Specimen fixing device
By designing a specimen fixation device suitable for Micro-CT scanning, the problem of unstable fixation of ex vivo bone tissue specimens was solved, achieving high-precision and efficient scanning results, and saving scanning time and costs.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- SHANGHAI EAST HOSPITAL EAST HOSPITAL TONGJI UNIV SCHOOL OF MEDICINE
- Filing Date
- 2025-07-21
- Publication Date
- 2026-05-26
AI Technical Summary
In current Micro-CT scans, excised bone tissue specimens are not easily fixed and are prone to displacement, resulting in low scanning accuracy, low efficiency, wasted space, and increased scanning costs.
A specimen fixation device was designed, including a base, a support rod, a connecting arm, and a clamp. The specimen is stably clamped by a combination of fixed clamping plates and movable clamping plates, combined with a slider and fastening bolts. It can accommodate specimens of different diameters and make full use of the scanning space through a detachable structure.
This method achieves stable specimen clamping, avoids displacement and vibration and airflow during scanning, improves scanning accuracy and efficiency, and saves time and costs.
Smart Images

Figure CN224286776U_ABST
Abstract
Description
Technical Field
[0001] This utility model relates to a fixing device, and in particular discloses a specimen fixing device. Background Technology
[0002] The Micro-CT scanner is a CT device with ultra-high spatial resolution, currently widely used in preclinical scientific research. Its largest application is in ex vivo bone microscopic imaging, utilizing the ultra-high spatial resolution of Micro-CT to observe microscopic structures within bones, such as trabeculae. This process mainly includes three steps: projection, reconstruction, and visualization. In the projection stage, a tiny sample passes through the rotating platform of the Micro-CT scanner and is irradiated by an X-ray beam, generating a series of projected images. In the reconstruction stage, these projected images are processed by a computer to form a three-dimensional image. Finally, in the visualization stage, computer software processes and analyzes the three-dimensional image to obtain information such as the sample's morphology, structure, and composition.
[0003] Currently, when using micro-CT to scan ex vivo bone tissue, there is no dedicated support for fixing the specimen. Often, a crude method is used: the ex vivo bone tissue specimen is simply placed on a self-made foam board and then secured with tape before scanning. This technique has many drawbacks: First, during micro-CT scanning, slight vibrations of the bed and airflow within the instrument can cause specimen displacement; even after manual fixation, using tape can still lead to shifting, which is time-consuming, labor-intensive, and inaccurate. Second, it doesn't fully utilize the scanning tube space, wasting space and increasing scanning time, thus increasing scanning costs and reducing research efficiency. Utility Model Content
[0004] The purpose of this invention is to overcome the defects in the existing technology and provide a specimen fixation device for Micro-CT scanning of ex vivo bone tissue specimens, which facilitates the fixation of ex vivo bone tissue specimens, prevents specimen movement, makes full use of the scanning tube space, and improves scanning efficiency.
[0005] This utility model is implemented as follows: A specimen fixing device includes a base, a support rod, a connecting arm, and a clamp. The support rod is vertically fixed to the base, and the support rod is provided with 1-5 layers of fixing frame groups. Each layer of the fixing frame group includes 3-8 connecting arms and clamps corresponding to each connecting arm. The clamp includes a fixed clamp, a movable clamp, a fastening bolt, and a slider. One end of the connecting arm is connected to the support rod, the fixed clamp is fixed to the other end of the connecting arm, the movable clamp is slidably connected to the connecting arm through the slider, and the slider is relatively sliding or relatively fixed to the connecting arm through the fastening bolt.
[0006] The support rod consists of 3 detachable unit rods. Each pair of adjacent unit rods is connected by a plug-in, telescopic, or threaded structure. The top of each unit rod is provided with a connector around its perimeter. The side of the connector is provided with 3-8 mounting surfaces corresponding to the connecting arm. One end of the connecting arm is connected to the mounting surface.
[0007] The mounting plane is provided with a connector, the wall of which is composed of 3-6 elastic legs, with a gap between each pair of adjacent elastic legs; a fastening nut is provided on the outside of the connector wall, and the fastening nut is connected to the elastic legs by threads; one end of the connecting arm is provided with a plug rod that mates with the connector; the plug rod is located inside the connector and is fixed by the fastening nut.
[0008] The fixed clamp and the movable clamp form a specimen holding space; the lateral width of the specimen holding space is 1-20mm; the connecting arm is provided with a scale corresponding to the lateral width of the specimen holding space, and at least one side of the slider is a straight edge corresponding to the scale.
[0009] The inner sidewalls of the fixed clip and the movable clip are respectively provided with anti-slip layers.
[0010] The height of each layer of the fixed frame assembly is 25-40mm.
[0011] The base is provided with a counterweight groove for placing a counterweight block.
[0012] The overall outer diameter of the fixed frame assembly is smaller than the outer diameter of the base.
[0013] The beneficial effects of this utility model are as follows: the fixed clamp and the movable clamp achieve the clamping of the specimen; the movable clamp slides on the connecting arm via the slider, thereby adjusting the size of the clamping space, which is convenient for clamping specimens of different diameters and has better adaptability; the movable clamp is tightened by the fastening bolt, making the clamping more stable and preventing specimen displacement. Correspondingly, during micro-CT scanning, the vibration of the bed and the airflow inside the instrument are avoided, thus preventing specimen displacement. It is also time-saving, labor-saving, and highly accurate.
[0014] Secondly, it can make full use of the space in the scanning tube, avoiding waste of space and reducing scanning time, thereby reducing scanning costs and improving research efficiency, thus achieving the goals of saving scanning time, making full use of space, and scanning accurately. Attached Figure Description
[0015] Figure 1 This is a top view of the structure of this utility model.
[0016] Figure 2 This is a schematic diagram of the insertion tube and fastening nut of this utility model.
[0017] Figure 3 This is a schematic diagram of the connection structure of the base, support rod, connecting arm, and clamp of this utility model.
[0018] Figure 4 yes Figure 3 A schematic diagram of the structure exploded.
[0019] The components include: 1. Base; 2. Support rod; 3. Connecting arm; 4. Clamping body; 5. Fixed clamping plate; 6. Moving clamping plate; 7. Fastening bolt; 8. Slider; 9. Unit rod; 10. Connector; 11. Mounting plane; 12. Insertion pipe; 13. Flexible foot; 14. Gap; 15. Fastening nut; 16. Insertion rod; 17. Specimen clamping space; 18. Scale; 19. Anti-slip layer; 20. Counterweight groove. Detailed Implementation
[0020] according to Figures 1-4 This utility model relates to a specimen fixing device, comprising a base 1, a support rod 2, a connecting arm 3, and a clamp 4. The support rod 2 is vertically fixed to the base 1. The base 1 is provided with a counterweight groove 20 for placing counterweight blocks. In use, counterweight blocks can be added or removed according to the weight of the specimen and other needs. The support rod 2 is provided with 1-5 layers of fixing frame assemblies, preferably 3 layers. The height of each fixing frame assembly is 25-40mm, preferably 30mm. Each layer of the fixing frame assembly includes 3-8 connecting arms 3 and clamping bodies 4 corresponding to each connecting arm 3. Each clamping body 4 includes a fixing clamping piece 5, a movable clamping piece 6, a fastening bolt 7, and a slider 8. One end of each connecting arm 3 is directly or indirectly connected to the support rod 2, and the axis of the connecting arm 3 is perpendicular to the axis of the support rod 2. The fixing clamping piece 5 is fixed to the other end of the connecting arm 3, and the movable clamping piece 6 is fixed to the slider 8. The movable clamping piece 6 is slidably connected to the connecting arm 3 via the slider 8. Preferably, the connecting arm 3 has a rectangular cross-section, and the slider 8 is fitted onto the connecting arm 3. The slider 8 is relatively slidable or relatively fixed to the connecting arm 3 via the fastening bolt 7. When the fastening bolt 7 is tightened, the slider 8 is fixed to the connecting arm 3; when the fastening bolt 7 is loosened, the slider 8 slides freely on the connecting arm 3. The overall outer diameter of the fixing frame assembly is smaller than the outer diameter of the base 1.
[0021] Preferably, the support rod consists of three detachable unit rods 9, and each pair of adjacent unit rods 9 are connected by a plug-in, telescopic, or threaded structure. Figure 4The components are connected by a threaded structure. The top of the unit rod 9 is provided with a connecting body 10 around its perimeter. The side of the connecting body 10 is provided with 3-8 mounting surfaces 11 corresponding to the connecting arm 3. One end of the connecting arm 3 is connected to the mounting surface 11.
[0022] Specifically, the mounting plane 11 is provided with a connector 12, the wall of which is composed of 3-6 elastic legs 13, with a gap 14 between each pair of adjacent elastic legs 13; a fastening nut 15 is provided on the outside of the connector 12, and the fastening nut 15 is connected to the elastic legs 13 by threads; one end of the connecting arm 3 is provided with a plug rod 16 that mates with the connector 12; the plug rod 16 is located inside the connector 12 and is fixed by the fastening nut 15. The diameter of the connector 12 near the support rod 2 is smaller than the diameter of the other end of the connector 12; by rotating the fastening nut 15, the elastic legs 13 can be pressed onto the plug rod 16.
[0023] A specimen holding space 17 is formed between the fixed clamp 5 and the movable clamp 6; the lateral width of the specimen holding space 17 is 1-20mm, preferably 2-15mm; the connecting arm 3 is provided with a scale 18 corresponding to the lateral width of the specimen holding space 17, and at least one side of the slider 8 is a straight edge corresponding to the scale 18, which is the scale reading reference edge. Anti-slip layers 19 are respectively provided on the inner sidewalls of the fixed clamp 5 and the movable clamp 6.
[0024] In use, this invention uses the clamp 4 to hold and fix isolated bone tissue specimens, and is particularly suitable for holding and fixing isolated bone specimens of rats and mice. The slider 8 drives the movable clamp 6 to slide on the connecting arm 3, allowing adjustment of the clamping space to accommodate specimens of different diameters and improve adaptability. The movable clamp is secured with bolts, ensuring stable clamping and preventing specimen displacement. Consequently, during micro-CT scanning, it avoids bed vibration and airflow within the instrument, thus preventing specimen shifting, saving time and effort, and providing high accuracy. The connecting arm 3 also has a scale 18, allowing the lateral width of the clamped portion of the isolated bone tissue specimen to be read via one straight edge of the slider 8 after fixation, facilitating specimen classification. The fixing frame assemblies of layers 1-5 are detachably connected, making them more convenient to use, clean, and disinfect. Each fixing frame assembly is equipped with 3-8 connecting arms and clamps 4. During scanning, this utility model and the fixed ex vivo bone tissue specimen are placed together in the scanning space of the scanning tube, which can make full use of the scanning space of the scanning tube and greatly improve scanning efficiency.
Claims
1. A specimen fixation device, characterized in that: The device includes a base, a support rod, connecting arms, and clamps. The support rod is vertically fixed to the base. The support rod has 1-5 layers of fixing frame groups. Each layer of the fixing frame group includes 3-8 connecting arms and clamps corresponding to each connecting arm. The clamps include a fixing clamp, a moving clamp, a fastening bolt, and a slider. One end of each connecting arm is connected to the support rod. The fixing clamp is fixed to the other end of the connecting arm. The moving clamp is slidably connected to the connecting arm via the slider. The slider is either relatively sliding or relatively fixed to the connecting arm via the fastening bolt.
2. The specimen fixation device according to claim 1, characterized in that: The support rod consists of 3 detachable unit rods. Each pair of adjacent unit rods is connected by a plug-in, telescopic, or threaded structure. The top of each unit rod is provided with a connector around its perimeter. The side of the connector is provided with 3-8 mounting surfaces corresponding to the connecting arm. One end of the connecting arm is connected to the mounting surface.
3. A specimen fixation device according to claim 2, characterized in that: The mounting plane is provided with a connector, the wall of which is composed of 3-6 elastic legs, with a gap between each pair of adjacent elastic legs; a fastening nut is provided on the outside of the connector wall, and the fastening nut is connected to the elastic legs by threads; one end of the connecting arm is provided with a plug rod that mates with the connector; the plug rod is located inside the connector and is fixed by the fastening nut.
4. The specimen fixation device according to claim 1, characterized in that: The fixed clamp and the movable clamp form a specimen holding space; the lateral width of the specimen holding space is 1-20mm; the connecting arm is provided with a scale corresponding to the lateral width of the specimen holding space, and at least one side of the slider is a straight edge corresponding to the scale.
5. A specimen fixation device according to claim 1 or 4, characterized in that: The inner sidewalls of the fixed clip and the movable clip are respectively provided with anti-slip layers.
6. A specimen fixation device according to claim 1, characterized in that: The height of each layer of the fixed frame assembly is 25-40mm.
7. A specimen fixation device according to claim 1, characterized in that: The base is provided with a counterweight groove for placing a counterweight block.
8. A specimen fixation device according to claim 1, characterized in that: The overall outer diameter of the fixed frame assembly is smaller than the outer diameter of the base.