A platelet-rich plasma preparation device

Abstract

The utility model discloses a kind of platelet-rich plasma preparation devices, it is related to medical instrument technical field;To solve the problem that blood separation mode is easy to pour red blood cell, inconvenient operation, and platelet recovery rate and efficiency are lower, the following technical scheme is proposed: it includes storage cavity, separation cavity and handle, the lower end of separation cavity is arranged in storage cavity, the lower end of storage cavity rotatably sets handle, the upper end surface of separation cavity is clamped with upper cover, and the lower connecting end of storage cavity is equipped with lower cover;Storage cavity is nested in reversal portion, and the cavity of storage cavity is communicated with separation cavity through reversal portion, and the lower chamber of storage cavity is equipped with piston, and the lower end surface of piston is abutted with the thread rod end surface of handle.The utility model realizes the complete independent separation storage of platelet-rich layer, plasma layer and red blood cell layer after whole blood centrifugal separation.Improve work efficiency and recovery rate, also ensure the safety and reliability of blood treatment, with extensive application prospect and popularization value.

Description

Technical Field

[0001] This utility model relates to the field of medical device technology, specifically to a platelet-rich plasma preparation device. Background Technology

[0002] With the rapid development of biomedical technology, research on human blood has become increasingly sophisticated. Blood is mainly composed of plasma, platelets, white blood cells, and red blood cells. Each component has its corresponding important role and different medical effects. For example, platelets used in the affected area help with cell generation, tissue repair, and wound healing. However, if red blood cells are mixed in with platelets, it can cause inflammation at the affected area. Therefore, if these components in the blood can be successfully separated and used in medicine to achieve adjunctive therapeutic effects, it will greatly improve medical efficacy.

[0003] Currently, the most common method for preparing separated blood is single or double centrifugation. During centrifugation, the blood separates into three layers under high-speed rotation: a plasma layer, a platelet-rich white blood cell layer, and a red blood cell layer. The industry currently mostly uses a tilting pouring method to extract these layers. However, this pouring process is not conducive to complete separation of the layers and easily spills red blood cells, resulting in red blood cells mixed in with the white blood cell layer. Furthermore, this method is inconvenient to operate, has low platelet recovery rates and efficiency, and also suffers from problems such as easy bacterial contamination of the blood within the equipment. Utility Model Content

[0004] The purpose of this invention is to provide a platelet-rich plasma preparation device to solve the problems of existing blood separation methods, such as easy dumping of red blood cells, inconvenient operation, and low platelet recovery rate and efficiency.

[0005] The technical solution of this utility model to solve the above-mentioned technical problems is as follows:

[0006] A platelet-rich plasma preparation device includes: a storage chamber, a separation chamber, and a handle. The lower end of the separation chamber is disposed in the storage chamber, and the handle is rotatably disposed at the lower end of the storage chamber. An upper cover is snapped onto the upper end of the separation chamber, and a lower cover is provided at the lower connecting end of the storage chamber.

[0007] The storage cavity is nested with a reversing part, which connects the storage cavity to the separation cavity. The lower chamber of the storage cavity is equipped with a piston, and the lower end face of the piston abuts against the threaded rod end face of the handle.

[0008] Preferably, the commutation unit includes a commutation ring, with an upper mating nozzle on the upper end face and a lower mating nozzle on the lower end face, the upper mating nozzle and the lower mating nozzle being connected through an eccentric through hole.

[0009] Preferably, an upper sealing ring is provided between the separation chamber and the upper cover, and a lower sealing ring is provided between the separation chamber and the upper end face of the reversing part.

[0010] Preferably, the separation chamber includes a first chamber and a second chamber fitted inside the first chamber. The first chamber is provided with a longitudinal reinforcing rib outside, and a hand-grip rotating part is fitted outside the reinforcing rib.

[0011] Preferably, both the lower ends of the first chamber and the second chamber are provided with through holes, which are connected to the reversing section.

[0012] Preferably, the upper surface of the lower sealing ring is provided with a snap-fit ​​block, which cooperates with the snap-fit ​​groove provided on the lower end face of the separation chamber.

[0013] Preferably, multiple limiting grooves are formed on the circumferential surface of the commutator, and the limiting grooves cooperate with the limiting posts set on the inner wall of the storage cavity.

[0014] Preferably, a funnel-shaped eccentric hole is formed inside the storage cavity, and the eccentric hole is connected to the lower connecting nozzle.

[0015] Preferably, a protective sleeve is fitted around the eccentric hole, and the eccentric hole is connected to the eccentric through hole.

[0016] This utility model has the following beneficial effects:

[0017] Highly efficient and stable separation: Through simple rotation, this apparatus can efficiently and stably achieve completely independent storage of the platelet-rich layer, plasma layer, and erythrocyte layer after whole blood centrifugation. This design simplifies the operation steps and reduces operational errors and mistakes that may occur in traditional preparation processes, thereby improving the efficiency and stability of the entire preparation process.

[0018] Improved platelet recovery rate and efficiency: Because this preparation device allows for completely independent storage of each blood layer, it effectively prevents red blood cells from contaminating the platelets. This design not only improves platelet purity but also significantly enhances platelet recovery rate and efficiency, making the prepared platelet-rich plasma more suitable for clinical use.

[0019] Excellent sealing: The preparation device employs multiple sealing measures in its structure, such as sealing rings and snap-fit ​​blocks, to ensure a tight connection and seal between all components. This design effectively prevents cross-contamination between blood and the external environment, guaranteeing the safety and reliability of the prepared platelet-rich plasma.

[0020] Flexible and adjustable chamber design: The separator can be designed with multiple chambers to flexibly adjust the number and capacity of chambers according to actual needs. This design makes the separator suitable for blood processing needs of different volumes, improving its applicability and flexibility.

[0021] Easy to observe and operate: The entire preparation device is made of transparent material, allowing operators to clearly see the blood separation process and results. This design not only improves the aesthetics of the device but also makes it easier for operators to observe and operate, thereby further improving the accuracy and safety of the preparation process. Attached Figure Description

[0022] Figure 1 This is a schematic diagram of the overall structure of the platelet-rich plasma preparation device of this utility model;

[0023] Figure 2 for Figure 1 Overall structural cross-sectional diagram;

[0024] Figure 3 and Figure 4 This is a schematic diagram of the separation chamber structure of the platelet-rich plasma preparation device of this utility model;

[0025] Figure 5 and Figure 6 This is a schematic diagram of the overall structure of the commutation unit;

[0026] Figure 7 This is a schematic diagram showing the connection between the reversing section, the separation chamber, and the storage chamber;

[0027] Figure 8 This is a schematic diagram of the storage cavity structure;

[0028] Figure 9 This is a schematic diagram of the upper cover structure;

[0029] Figures 1 to 9 The reference numerals in the accompanying drawings represent: storage cavity 1, reversing part 11, reversing ring 111, upper docking nozzle 112, lower docking nozzle 113, eccentric through hole 114, snap-fit ​​block 115, limiting groove 116, snap-fit ​​post 12, limiting post 13, sheath 15, upper connecting end 16, lower connecting end 17, chamber marking 18, separation cavity 2, first chamber 21, second chamber 22, reinforcing rib 23, snap fastener 24, through hole 25, upper sealing ring 26, lower sealing ring 27, snap groove 28, locking indicator marking 29, handle 3, piston 31, upper cover 4, extraction hole 41, vent hole 42, lower cover 5, and hand-held rotating part 6. Detailed Implementation

[0030] The technical solution of this utility model will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of this utility model, and not all embodiments. Based on the embodiments of this utility model, all other embodiments obtained by those skilled in the art without creative effort are within the protection scope of this utility model.

[0031] Please refer to Figure 1-2 To achieve efficient and stable platelet separation and storage, this invention proposes a novel platelet-rich plasma preparation device. Through innovative structural design, this device enables completely independent storage of the platelet-rich layer, plasma layer, and erythrocyte layer after whole blood centrifugation within a single instrument. The following is a detailed description of the specific embodiments of this invention.

[0032] First, the platelet-rich plasma (PRP) preparation device of this invention mainly includes a storage chamber 1, a separation chamber 2, a handle 3, an upper cover 4, and a lower cover 5. The storage chamber 1 is the main body of the device, used to store whole blood before centrifugation, as well as the plasma layer, platelet-rich white blood cell layer, and red blood cell layer that will be separated from top to bottom after centrifugation. The storage chamber 1 is designed in a cylindrical or similar shape to facilitate blood storage and centrifugation operations.

[0033] The separation chamber 2 is a key component of this invention, comprising multiple rotatable and switchable chambers. The design of these chambers allows for the separate delivery of each blood layer into its corresponding chamber after centrifugation. The upper end of the separation chamber 2 is sealed tightly with a top cover 4 to prevent external contamination. An upper sealing ring 26 is provided between the top cover 4 and the separation chamber 2 to enhance the sealing effect. The lower end of the separation chamber 2 is located inside the storage chamber 1 and can be switched between connected and closed states with the storage chamber 1.

[0034] The handle 3 is the power component in this invention, used to move the layered blood in the storage cavity 1 from bottom to top. The threaded end face of the handle 3 abuts against the lower end face of the piston 31 in the lower chamber of the storage cavity 1. By rotating the handle 3, the piston 31 can be driven to move upward inside the storage cavity 1, thereby pushing the blood layer by layer upward.

[0035] Reference Figure 9 The top cover 4 not only seals the separation chamber 2 tightly but also has extraction holes 41 on it. These extraction holes 41 correspond to the through holes on the lower end faces of each chamber of the separation chamber 2, facilitating the extraction of the completely separated layers from each chamber. A plug is fitted over the extraction hole 41 to prevent blood leakage. Simultaneously, a vent 42 is also provided on the top cover 4, with an isolation membrane installed inside. The isolation membrane prevents bacteria from entering while simultaneously allowing gas to escape from the chamber, reducing internal pressure. The isolation membrane can be made of materials such as medical dialysis paper.

[0036] The lower cover 5 is connected to the lower connection end 17 of the storage cavity 1 by threads to fix the handle 3 and the piston 31. The design of the lower cover 5 makes the entire preparation device more stable and easier to operate.

[0037] Inside the storage chamber 1, a reversing section 11 is also fixedly installed. The function of the reversing section 11 is to divide the storage chamber 1 into two chambers: the upper chamber is used for docking and installing the separation chamber 2, and the lower chamber houses the piston 31. Blood is stored between the piston 31 and the reversing section 11. The design 1 of the reversing section 1 allows blood to flexibly switch between connected and blocked states between the storage chamber 1 and the separation chamber 2.

[0038] Reference Figure 5-6 Specifically, the reversing unit 11 includes a reversing ring 111. The upper end face of the reversing ring 111 is provided with an upper docking nozzle 112, and the lower end face is provided with a lower docking nozzle 113. The upper docking nozzles 112 and 113 are connected by an eccentric through hole 114. This eccentric design allows different chambers to be switched to communicate with the reversing unit 11 when rotating the separation chamber 2.

[0039] To ensure a tight seal, a lower sealing ring 27 is used to seal the lower end face of the separation chamber 2 and the upper end face of the reversing part 11. The upper surface of the lower sealing ring 27 is also provided with snap-fit ​​blocks 115, which cooperate with the snap-fit ​​grooves 28 provided on the lower end face of the separation chamber 2 to prevent the lower sealing ring 27 from falling off the upper end face of the reversing part 11 when the separation chamber 2 is rotated.

[0040] In addition, multiple limiting grooves 116 are formed on the circumferential surface of the commutator 111. These limiting grooves 116 cooperate with the limiting posts 13 provided on the inner wall of the storage cavity 1 to fix the position of the commutator 11. This design allows the commutator 11 to remain stable when the separation cavity 2 is rotated.

[0041] Reference Figure 3-4 The design of the separation chamber 2 is also ingenious. It includes two separation chambers: a first chamber 21 and a second chamber 22. The second chamber 22 is fitted inside the first chamber 21 to save space and increase stability. The grip rotation part 6 is fitted onto the outside of the first chamber 21 by one or more annular longitudinal reinforcing ribs 23. These reinforcing ribs 23 not only enhance the structural strength of the separation chamber 2, but also provide support points for the grip rotation part 6.

[0042] Each chamber has a through hole 25 on its lower end face to mate with the reversing part 11. A long strip-shaped buckle 24 is provided on the lower end face of the reinforcing rib 23 near the locking indicator 29. The buckle 24 has a groove that can cooperate with one of the multiple locking posts 12 on the outer wall of the connecting end 16 on the storage chamber 1. This design allows the chambers to be temporarily locked when the rotating part 6 is rotated, facilitating operation.

[0043] An eccentric, funnel-shaped orifice is also provided inside the storage cavity 1. The eccentric orifice communicates with the lower connecting nozzle 113 to guide blood from the storage cavity 1 into the switching section 11. The design of the eccentric orifice prevents fluid accumulation and makes platelet collection smoother, easier, and less wasteful. A sheath 15 is also fitted over the eccentric orifice, which serves to connect and seal between the eccentric orifice and the eccentric through-hole 114.

[0044] In practice, whole blood is first injected into the lower chamber of storage chamber 1. This can be achieved by inserting a syringe into the extraction port 41, which corresponds to the through-hole on the lower end face of each chamber of separation chamber 2, on the upper cover 4. After injection, centrifugation is performed. After centrifugation, the whole blood will separate into three layers from top to bottom: a plasma layer, a platelet-rich white membrane layer, and a red blood cell layer.

[0045] Next, by rotating the handle 3, the piston 31 is moved upward, pushing the red blood cell layer into the upper chamber of the storage chamber 1. At this time, due to the sealing effect of the lower sealing ring 27, the red blood cell layer will not flow into the separation chamber 2. Then, by rotating the handle rotating part 6, the communication state between the internal chamber of the separation chamber 2 and the reversing part 11 is switched. When the first chamber 21 is connected to the reversing part 11, the piston 31 is continued to be pushed to push the plasma layer into the first chamber 21. Similarly, when the second chamber 22 is connected to the reversing part 11, the platelet-rich white membrane layer is pushed into the second chamber 22.

[0046] Finally, the plasma layer in the first chamber 21 and the platelet-rich white membrane layer in the second chamber 22 are extracted through the extraction holes 41 on the top cover 4. A syringe or tubing can be used for extraction. After extraction, the entire apparatus is cleaned and sterilized for future use.

[0047] It should be noted that this embodiment only shows the two-chamber separation chamber 2. The larger first chamber 21 is used to store the separated plasma layer, and the smaller second chamber 22 is used to store the separated platelet-rich white membrane layer. The red blood cell layer remains in the lower chamber of the storage chamber 1. After rotating the rotating part 6 to align and lock the indicator mark on the separation chamber with the chamber mark 18 of the storage chamber 1 at position 0, the chambers of the separation chamber 2 are completely separated from the eccentric through-hole 114 of the reversing ring 111 by the lower sealing ring 27. The chambers of the separation chamber are in a closed state. The upper sealing ring 26, the lower sealing ring 27, and the isolation membrane can prevent the blood layers from being contaminated by the outside world and can also prevent accidental blood leakage and mixing or environmental contamination. Of course, in other optional embodiments, the separation chamber 2 can also be designed with three or more chambers so that the red blood cell layer can also be separated and extracted into one chamber of the separation chamber. In this way, the number of chambers of the separation chamber 2 can be flexibly adjusted according to actual needs.

[0048] Furthermore, to facilitate observation and operation of the entire separation and extraction process, the entire preparation device is preferably made of transparent material. The choice of transparent material not only allows operators to clearly see the blood separation process and results, but also improves the aesthetics and safety of the preparation device.

[0049] The advantages of this invention are: through a simple rotational operation, it can efficiently and stably separate and store the platelet-rich layer, plasma layer, and erythrocyte layer completely independently within a single separator. This design not only simplifies the operation steps and improves work efficiency, but also effectively prevents erythrocytes from mixing with platelets, thereby improving platelet recovery rate and efficiency. Simultaneously, the well-sealed design prevents cross-contamination between blood and the external environment.

[0050] In practice, the structure and parameters of the preparer can be adjusted and optimized according to actual needs. For example, the shape and size of the storage chamber 1 and the separation chamber 2 can be adjusted to meet the needs of blood processing of different volumes; the design of the reversing part 11 and the limiting post 13 can be optimized to improve the stability and accuracy of reversal; and the design of the extraction hole 41 and the plug can be improved to enhance the convenience and safety of extraction operations.

[0051] In summary, this novel platelet-rich plasma (PRP) preparer, through its innovative structural design and ingenious operation, achieves completely independent storage of the platelet-rich layer, plasma layer, and erythrocyte layer after whole blood centrifugation. This design not only improves work efficiency and recovery rate but also ensures the safety and reliability of blood processing. Therefore, this invention has broad application prospects and promotional value in the field of blood processing technology.

[0052] The above description is only a preferred embodiment of the present utility model and is not intended to limit the present utility model. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present utility model should be included within the protection scope of the present utility model.

Claims

1. A platelet-rich plasma (PRP) generator, characterized in that, include: Storage cavity (1), separation cavity (2) and handle (3), the lower end of the separation cavity (2) is disposed in the storage cavity (1), the handle (3) is rotatably disposed at the lower end of the storage cavity (1), the upper end face of the separation cavity (2) is snapped with the upper cover (4), the lower connecting end (17) of the storage cavity (1) is provided with the lower cover (5); the storage cavity (1) is nested with a reversing part (11), the storage cavity (1) is connected to the chamber of the separation cavity (2) through the reversing part (11), the lower chamber of the storage cavity (1) is provided with a piston (31), the lower end face of the piston (31) abuts against the threaded rod end face of the handle (3).

2. The platelet-rich plasma preparation device according to claim 1, characterized in that, The reversing part (11) includes a reversing ring (111), the upper end face of the reversing ring (111) is provided with an upper docking nozzle (112), the lower end face of the reversing ring (111) is provided with a lower docking nozzle (113), and the upper docking nozzle (112) and the lower docking nozzle (113) are connected through an eccentric through hole (114).

3. The platelet-rich plasma preparation device according to claim 1, characterized in that, An upper sealing ring (26) is provided between the separation chamber (2) and the upper cover (4), and a lower sealing ring (27) is provided between the separation chamber (2) and the upper end face of the reversing part (11).

4. The platelet-rich plasma preparation device according to claim 1, characterized in that, The separation chamber (2) includes a first chamber (21) and a second chamber (22) sleeved on the first chamber (21). The first chamber (21) is provided with a longitudinal reinforcing rib (23), and a hand gripping rotating part (6) is sleeved on the outside of the reinforcing rib (23).

5. The platelet-rich plasma preparation device according to claim 4, characterized in that, The lower ends of the first chamber (21) and the second chamber (22) are provided with through holes (25) and are connected to the reversing part (11) through the through holes (25).

6. The platelet-rich plasma preparation device according to claim 3, characterized in that, The upper surface of the lower sealing ring (27) is provided with a snap-fit ​​block (115), which cooperates with the snap-fit ​​block (115) and the slot (28) provided on the lower end face of the separation chamber (2).

7. The platelet-rich plasma preparation device according to claim 2, characterized in that, The commutator (111) has multiple limiting grooves (116) on its circumferential surface, and the limiting grooves (116) cooperate with the limiting posts (13) provided on the inner wall of the storage cavity (1).

8. The platelet-rich plasma preparation device according to claim 2, characterized in that, The storage cavity (1) has a funnel-shaped eccentric hole, which is connected to the lower nozzle (113).

9. The platelet-rich plasma preparation device according to claim 8, characterized in that, The eccentric hole is covered with a protective sleeve (15), and the eccentric hole is connected to the eccentric through hole (114).

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