A floating type vibration mixing device and a cell staining apparatus

Abstract

The utility model provides a kind of floating type's vibration mixing device and cell staining equipment, floating type's vibration mixing device includes slide loading and unloading mechanism, vibration motor, height adjusting mechanism and base, slide loading and unloading mechanism includes slide rack, glass slide and limit post, installation groove is opened on slide rack, glass slide is set in installation groove, slide rack front part is equipped with limit block, glass slide one end abuts limit block, limit post is set in the both sides and rear portion of slide rack, vibration motor is fixedly arranged below slide loading and unloading mechanism, height adjusting mechanism is located between slide loading and unloading mechanism and base.The device simple structure, there is no any shelter above slide, it is convenient for operator to load and unload glass slide.

Description

Technical Field

[0001] This utility model belongs to the field of material mixing technology, and specifically relates to a floating vibration mixing device and a cell staining equipment. Background Technology

[0002] Currently, fully automated immunohistochemical staining machines are widely used in routine pathological diagnosis and scientific research. However, existing immunohistochemical staining equipment and methods require excessively long testing times, making it impossible to perform rapid immunohistochemical staining on frozen sections and support pathologists in making accurate diagnoses of frozen sections in a short time. This patent utilizes mechanical vibration to accelerate antibody molecule movement, increase the efficiency of antigen-antibody collision and binding, speed up the antigen-antibody reaction, and shorten the antigen-antibody reaction time.

[0003] The existing document CN202410543389.8 describes a rapid immunohistochemical staining machine, which also aims to increase the chances of antibody-antigen collision and binding, thereby accelerating the antigen-antibody reaction. However, in this scheme, the accelerator structure for accelerating the reaction is complex, the reaction port restricts the area where the operator can place tissue, and the precise limitation of the sliding shaft's installation height may affect the loading and unloading of slides and the accelerator's effectiveness. Utility Model Content

[0004] In order to solve the above-mentioned problems in the prior art, this application provides a floating vibration mixing device and a cell staining device to solve the above-mentioned technical defects.

[0005] According to a first aspect of this utility model, a floating vibration mixing device is proposed, comprising a slide loading and unloading mechanism, a vibration motor, a height adjustment mechanism, and a base. The slide loading and unloading mechanism includes a slide holder, a slide, and limiting posts. The slide holder has an installation groove, in which the slide is placed. A limiting block is provided at the front of the slide holder, with one end of the slide abutting against the limiting block. The limiting posts are located on both sides and the rear of the slide holder. The vibration motor is fixedly located below the slide loading and unloading mechanism. The height adjustment mechanism is located between the slide loading and unloading mechanism and the base. By using the limiting block at the front of the slide holder and the limiting posts on both sides and the rear of the slide holder, the slide is fixed to the slide holder, preventing displacement and detachment of the slide during cell staining. Furthermore, the device has a simple structure, with no obstructions above the slide, facilitating slide loading and unloading by the operator.

[0006] In a specific embodiment, the floating vibration mixing device also includes a flow guide channel, which is inclinedly arranged on both sides of the slide holder. This structural design can effectively prevent liquid splashing and liquid accumulation on the slide holder.

[0007] In a specific embodiment, the floating vibration mixing device also includes a heating film, which is disposed at the bottom of the slide holder. The function of the heating film is to provide a heating effect, providing the corresponding heating temperature required for the reaction of reagents with different reaction temperatures, thereby accelerating the reaction of the reagents.

[0008] In a specific embodiment, the floating vibration mixing device also includes a motor mounting base, in which a vibration motor is disposed. The motor mounting base is fixed to the lower part of the slide holder by screws. The main function of the vibration motor is to provide power to the slide holder, drive the slides on the slide holder to vibrate, increase the antigen-antibody collision and binding efficiency, shorten the antigen-antibody reaction time, and accelerate the cell staining process.

[0009] In a specific embodiment, a gap is left between the base and the slide holder. This structural design avoids the vibration motor causing the slide holder and the base to collide and generate noise during operation.

[0010] In a specific embodiment, the height adjustment mechanism includes a spring, an upper spring mounting seat, and a lower spring mounting seat, with the spring fixedly connected to the upper and lower spring mounting seats. This structure uses a spring to flexibly connect the slide holder to the base, which not only acts as a buffer, reducing the impact of the vibration motor on the floating vibration mixing device, but also reduces vibration noise.

[0011] In a specific embodiment, the upper spring mounting base is fixedly connected to the slide holder by screws, the lower spring mounting base has external threads, and the base has threaded holes, with the lower spring mounting base threadedly connected to the base. This structural design ensures a stable connection between the height adjustment mechanism, the slide holder, and the base; the upper spring mounting base is fixed, while the lower spring mounting base can be adjusted in height via its threads.

[0012] In a specific embodiment, the height adjustment mechanism is respectively set at the four corners of the slide holder and the base. This structure helps to maintain the stability of the device and at the same time enables the adjustment of the threads on the spring mounting base at the four corners.

[0013] In a specific embodiment, the height of the four corners of the slide holder can be adjusted by adjusting the depth of the threaded hole in the base on the lower spring mounting seat. This structural design prevents unevenness on the upper surface of the slide holder from causing liquid to flow off the slide.

[0014] According to a second aspect of the present invention, a cell staining apparatus is provided, comprising the floating vibration mixing device disclosed in the first aspect of the present invention.

[0015] Compared with the prior art, the beneficial results of this utility model are as follows:

[0016] 1. The slide loading and unloading mechanism of this utility model uses a limiting block at the front of the slide holder and limiting posts on both sides and the rear of the slide holder to fix the slides on the slide holder, preventing the slides from moving or falling off during the cell staining process.

[0017] 2. This utility model uses a spring to flexibly connect the slide holder and the base, which not only acts as a buffer to reduce the impact of the vibration motor on the device, but also reduces vibration noise.

[0018] 3. The height lifting mechanism of this utility model can adjust the height of the four corners of the slide holder by adjusting the lower spring seat, thereby preventing the liquid from flowing off the slide due to unevenness of the upper surface of the slide holder.

[0019] 4. This utility model has a simple structure with no obstructions above the glass slide, making it convenient for operators to load and unload the glass slide. Attached Figure Description

[0020] The accompanying drawings are included to provide a further understanding of the embodiments and are incorporated in and constitute a part of this specification. The drawings illustrate embodiments and, together with the description, serve to explain the principles of the present invention. Other embodiments and many anticipated advantages of the embodiments will be readily recognized as they become better understood through reference to the following detailed description. Elements in the drawings are not necessarily to scale. The same reference numerals refer to corresponding similar parts.

[0021] Figure 1 This is an exploded view of a floating vibration mixing device according to the first embodiment of the present invention;

[0022] Figure 2 This is a top view of a floating vibration mixing device according to the first embodiment of the present invention;

[0023] Figure 3 This is a schematic diagram of the bottom cross-sectional direction of the floating vibration mixing device according to the first embodiment of the present invention;

[0024] Figure 4 This is a cross-sectional view along direction A of the floating vibration mixing device according to the first embodiment of the present invention;

[0025] Figure 5 This is a schematic diagram of the floating vibration mixing device according to the first embodiment of the present invention, in direction B.

[0026] The meanings of the numbers in the diagram are as follows: 01-Slide holder, 02-Slide carrier, 03-Limiting post, 04-Base, 05-Heating film, 06-Spring mounting lower seat, 07-Spring, 08-Spring mounting upper seat, 09-Vibration motor, 10-Limiting block, 11-Slide loading and unloading mechanism, 12-Height adjustment mechanism, 13-Guide channel. Detailed Implementation

[0027] In the following detailed description, reference is made to the accompanying drawings, which form part of the detailed description and illustrate illustrative specific embodiments in which the present invention may be practiced. In this regard, directional terms such as “top,” “bottom,” “left,” “right,” “up,” “down,” etc., are used with reference to the orientation of the described figures. Because components of the embodiments can be positioned in several different orientations, directional terms are used for illustrative purposes and are by no means limiting. It should be understood that other embodiments may be utilized or logical changes may be made without departing from the scope of the present invention. Therefore, the following detailed description should not be taken in a limiting sense, and the scope of the present invention is defined by the appended claims.

[0028] This invention proposes a floating vibration mixing device and a cell staining equipment. Figure 1 An exploded view of the floating vibration mixing device according to the first embodiment of this utility model is shown, as follows: Figure 1 As shown, the floating vibration mixing device in this embodiment includes a slide holder 01, a slide 02, a limiting post 03, a base 04, a heating film 05, a lower spring mounting seat 06, a spring 07, an upper spring mounting seat 08, and a vibration motor 09. The heating film 05 is located at the bottom of the slide holder 01 to provide heating, providing the corresponding heating temperature required for the reaction of reagents with different reaction temperatures, thereby accelerating the reaction of the reagents. Two vibration motors 09 are fixedly located below the slide holder 01, and a height adjustment mechanism 12 is located between the slide holder 01 and the base 04.

[0029] In a specific embodiment, the vibration motor 09 is disposed in the motor mounting base, which is fixed to the lower part of the slide holder 01 by screws, providing power to the slide holder 01 and driving the slide 02 on the slide holder 01 to vibrate, thereby increasing the antigen-antibody collision and binding efficiency, shortening the antigen-antibody reaction time, and accelerating the cell staining process.

[0030] In a specific embodiment, the height adjustment mechanism 12 includes a lower spring mounting seat 06, a spring 07, and an upper spring mounting seat 08. The four height adjustment mechanisms 12 are respectively located at the four corners of the slide holder 01 and the base 04. This structure helps to maintain the stability of the floating vibration mixing device in this embodiment, and at the same time, it can adjust the threads on the lower spring mounting seat 06 at the four corners.

[0031] Figure 2 A top view of a floating vibration mixing device according to a first embodiment of the present invention is shown, as follows: Figure 2 As shown, the slide loading and unloading mechanism 11 includes a slide holder 01, a slide 02, and a limiting post 03. The slide holder 01 has an installation groove, in which the slide 02 is placed. A limiting block 03 is provided at the front of the slide holder 01, and one end of the slide 02 is close to the limiting block 03. Two limiting posts 03 are respectively provided on both sides of the slide holder 01, and one limiting post 03 is provided at the rear of the slide holder 01. By providing a limiting block 10 at the front of the slide holder 01 and limiting posts 03 on both sides and at the rear of the slide holder 01, the slide 02 is fixed on the slide holder 01, which can prevent the slide 02 from moving or falling off during cell staining.

[0032] In a specific embodiment, the floating vibration mixing device also includes a guide channel 13, which is inclinedly arranged on both sides of the slide holder 01. This structural design can effectively prevent liquid splashing and liquid accumulation on the slide holder 01.

[0033] Figure 3 A schematic diagram of the bottom cross-sectional direction of the floating vibration mixing device according to the first embodiment of this utility model is shown, as follows. Figure 3 As shown, there is a gap between the base 04 and the slide holder 01. This structural design prevents the slide holder 01 from colliding with the base 04 and generating noise during the operation of the vibration motor 09. It also prevents the liquid on the vibration motor 09 from flowing into the slide holder 01.

[0034] Figure 4 A cross-sectional view along direction A is shown for a floating vibrating mixing device according to a first embodiment of the present invention. Figure 3 Combination Figure 4 It can be seen that spring 07 is fixedly connected to upper spring mounting base 08 and lower spring mounting base 06. In this structural arrangement, spring 07 flexibly connects slide holder 01 to base 04, reducing the impact of vibration motor 09 on the floating vibration mixing device and also reducing vibration noise. Upper spring mounting base 08 is fixedly connected to slide holder 01 by screws, lower spring mounting base 06 has external threads, and base 04 has threaded holes 14, with lower spring mounting base 06 threadedly connected to base 04. This structural design ensures that height adjustment mechanism 12 is stably connected to slide holder 01 and base 04, with upper spring mounting base 08 fixed and lower spring mounting base 06 adjustable in height via threads.

[0035] In a specific embodiment, the spring mounting seat 08 can also be fixed to the slide holder 01 by welding, snap-fitting or other methods.

[0036] Figure 5A schematic diagram of the floating vibration mixing device according to the first embodiment of this utility model is shown in direction B. Combined with... Figure 3 and Figure 5 It can be seen that the depth of the mounting groove on the slide holder 01 is slightly deeper than the height of the slide 02, so that the slide 02 can be placed precisely into the mounting groove and is not easy to slip out. This structural design not only saves materials, but also makes loading and unloading the slide 02 more convenient. There is a gap between the vibration motor 09 and the heating film 05 set at the bottom of the slide holder 01. This structural design prevents the vibration motor 09 from colliding with the heating film 05 during operation.

[0037] In a specific embodiment, the steps for using the floating vibration mixing device are as follows: First, place one end of the glass slide 02 close to the limiting block 10 into the mounting groove on the slide holder 01, fix the position of the glass slide 02 by the limiting post 03, then adjust the spring mounting bases 06 at the four corners of the base 04 respectively, rotate the threads on the spring mounting bases 06 to change the height of the four corners of the slide holder 01, so that the surface of the slide holder 01 is horizontal, and then start the vibration motor 09 under the slide holder 01, and the device starts to work.

[0038] Obviously, those skilled in the art can make various modifications and changes to the embodiments of this utility model without departing from the spirit and scope of this utility model. In this way, this utility model is also intended to cover such modifications and changes if they fall within the scope of the claims of this utility model and their equivalents. The word "comprising" does not exclude the presence of other elements or steps not listed in the claims. The simple fact that certain measures are described in mutually different dependent claims does not indicate that a combination of these measures cannot be used for profit. Any reference numerals in the claims should not be considered as limiting the scope.

Claims

1. A floating vibration mixing device, characterized in that, The device includes a slide loading and unloading mechanism, a vibration motor, a height adjustment mechanism, and a base. The slide loading and unloading mechanism includes a slide holder, a slide carrier, and limiting posts. The slide holder has an installation groove, in which the slide carrier is placed. A limiting block is provided at the front of the slide holder, and one end of the slide carrier is close to the limiting block. The limiting posts are located on both sides and the rear of the slide holder. The vibration motor is fixedly installed below the slide loading and unloading mechanism, and the height adjustment mechanism is located between the slide loading and unloading mechanism and the base.

2. The vibration mixing device according to claim 1, characterized in that, It also includes flow channels, which are inclinedly arranged on both sides of the slide holder.

3. The vibration mixing device according to claim 1, characterized in that, It also includes a heating film disposed at the bottom of the slide holder.

4. The vibration mixing device according to claim 1, characterized in that, It also includes a motor mounting base, in which the vibration motor is disposed, and the motor mounting base is fixedly disposed to the lower part of the slide holder by screws.

5. The vibration mixing device according to claim 1, characterized in that, A gap is left between the base and the slide holder.

6. The vibration mixing device according to claim 1, characterized in that, The height adjustment mechanism includes a spring, an upper spring mounting seat, and a lower spring mounting seat, wherein the spring is fixedly connected to the upper spring mounting seat and the lower spring mounting seat.

7. The vibration mixing device according to claim 6, characterized in that, The upper spring mounting base is fixedly connected to the slide holder by screws, the lower spring mounting base is provided with external threads, the base is provided with threaded holes, and the lower spring mounting base is threadedly connected to the base.

8. The vibration mixing device according to claim 7, characterized in that, The height adjustment mechanisms are respectively located at the four corners of the slide holder and the base.

9. A vibration mixing device according to claim 8, characterized in that, The height of the four corners of the slide holder can be adjusted by adjusting the depth of the threaded hole in the base on the spring mounting base.

10. A cell staining apparatus, characterized in that, Includes the vibration mixing device according to any one of claims 1-9.

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