A highly integrated nano-optical sensor array

Abstract

The utility model discloses a kind of high integration nanometer optical sensing array, including body, sample placement tray is arranged in body, light source module, spectrometer, optical fiber probe, X-axis module and Y-axis module of the sample placement tray movement controlled, optical fiber probe includes input optical fiber, output optical fiber and probe part, the probe part of optical fiber probe is located in the upside of sample placement tray, the light emitted by light source module is transmitted to probe part by the input optical fiber of optical fiber probe, and by probe part, the light of emission is incident by probe part after reflecting on sample surface, and is transmitted to spectrometer by output optical fiber. The utility model will light source module, spectrometer, optical fiber probe, sample placement tray, X-axis module, Y-axis module encapsulation in body, avoid external light interference and mechanical vibration, improve the stability of environmental interference ability and signal acquisition;Gold reference site and multiple sample sites are integrated on sample placement tray, realize multiple sample sites nondestructive continuous detection, ensure the consistency and accuracy of measurement.

Description

Technical Field

[0001] This utility model relates to the field of optical detection equipment technology, specifically a highly integrated nano-optical sensing array. Background Technology

[0002] In fields such as nanomaterial characterization, biomolecule detection, and surface-enhanced spectroscopy (e.g., SERS), optical sensing technology has become a core research tool due to its non-destructive nature and high sensitivity. Among these technologies, surface plasmon resonance (SPR) technology generates locally enhanced surface plasmon waves by exciting collective oscillations of free electrons in metal nanostructures. When a target biomolecule specifically binds to a sensing chip modified with a metal surface, it causes a slight change in the interface refractive index, which in turn alters the plasmon resonance conditions, manifesting as a shift in the resonance angle or a change in the intensity of reflected light, thereby achieving highly sensitive detection.

[0003] However, traditional SPR sensing systems are typically assembled from separate modules such as light sources, spectrometers, and mechanical motion platforms, resulting in a complex and bulky overall structure. Furthermore, they are difficult to effectively shield against ambient light and mechanical vibration interference, significantly reducing the system's signal-to-noise ratio (SNR). In addition, multi-target detection requires manual replacement of sample sites and manual calibration, which is not only cumbersome and time-consuming but also introduces positioning errors, affecting the consistency and accuracy of the detection. Utility Model Content

[0004] To address the shortcomings of existing technologies, this invention provides a highly integrated nano-optical sensing array for SPR detection. It integrates a light source module, spectrometer, fiber optic probe, sample placement tray, X-axis module, and Y-axis module within a single unit, avoiding external light interference and mechanical vibration, thus improving environmental interference resistance and signal acquisition stability. The compact, integrated design enhances portability. The sample placement tray integrates a gold reference site and multiple sample sites, enabling non-destructive continuous detection of multiple sample sites without manual target replacement, reducing operational errors and ensuring measurement consistency and accuracy. Furthermore, the internal isolation plates and baffles provide electromagnetic and optical isolation, preventing any impact on signal acquisition accuracy.

[0005] To achieve the above objectives, this utility model employs the following technical solution:

[0006] A highly integrated nano-optical sensor array, comprising a housing, wherein the following are disposed within the housing:

[0007] The sample placement tray includes a gold reference position and multiple sample positions;

[0008] The X-axis module is used to control the movement of the sample placement tray along the X-axis.

[0009] The Y-axis module is used to control the sample placement tray, and the X-axis module moves along the Y-axis direction.

[0010] The light source module is used to provide the light source;

[0011] Spectrometer;

[0012] An optical fiber probe is located on the upper side of the sample placement tray. The optical fiber probe includes an input optical fiber, an output optical fiber, and a probe section connecting the input optical fiber and the output optical fiber. The input optical fiber is connected to the light source module, and the output optical fiber is connected to the spectrometer.

[0013] The light emitted by the light source module is transmitted to the probe section via the input optical fiber and then emitted from the probe section. The emitted light is reflected by the sample surface and then enters the probe section, and is transmitted to the spectrometer via the output optical fiber.

[0014] The light source module includes a light source, a lens group is provided on the optical path channel between the light source and the input optical fiber, and a heat dissipation shell is provided on the outer periphery of the light source.

[0015] The lens group includes a collimating lens and a focusing lens arranged sequentially from the light source side to the input optical fiber side.

[0016] A shutter module is provided between the focusing lens and the collimating lens. The shutter module includes a light-blocking plate and a drive mechanism for controlling the movement or rotation of the light-blocking plate.

[0017] An isolation plate is provided between the X-axis module and the Y-axis module, and the isolation plate is provided with a moving channel for the slide of the Y-axis module to move.

[0018] The probe section of the optical fiber probe is mounted on the isolation plate via an "L-shaped" bracket.

[0019] The machine body is also equipped with a baffle that separates the spectrometer, light source module and fiber optic probe, X-axis module and Y-axis module into two spaces.

[0020] The machine body is also equipped with a radiator and a fan; the sample placement tray of the machine body is provided with an opening for placing samples, and a door is movably installed at the opening.

[0021] The machine body contains an industrial control computer connected to the drive mechanisms of the light source module, X-axis module, Y-axis module, and shutter module.

[0022] The machine body is also equipped with a touch screen display and a USB port that connect to an industrial control computer.

[0023] Compared with the prior art, the advantages of this utility model are as follows:

[0024] 1. This invention integrates the light source module, spectrometer, fiber optic probe, sample placement tray, X-axis module, and Y-axis module into the body, avoiding external light interference and mechanical vibration, improving the resistance to environmental interference and the stability of signal acquisition; and the compact integrated structure design can improve the portability of this invention; the sample placement tray of this invention integrates a gold reference site and multiple sample sites, realizing non-destructive continuous detection of multiple sample sites, eliminating the need for manual target replacement, reducing operational errors, and ensuring the consistency and accuracy of measurements.

[0025] 2. In this invention, the collimating lens generates parallel light in front, the shutter module is placed in the parallel light path, and the focusing lens is coupled into the fiber optic probe, resulting in high light energy utilization and avoiding tilting and blocking losses.

[0026] 3. The isolation plate and baffle of this utility model provide electromagnetic and optical isolation to avoid affecting the accuracy of signal acquisition. Attached Figure Description

[0027] Appendix Figure 1 This is a schematic diagram of the external structure of this utility model.

[0028] Appendix Figure 2 This is a schematic diagram of the structure of the present invention after the external hatch is removed.

[0029] Appendix Figure 3 This is one of the internal structural diagrams of this utility model.

[0030] Appendix Figure 4 This is the second schematic diagram of the internal structure of this utility model.

[0031] Appendix Figure 5 This is a schematic diagram of the connection between the light source module and the spectrometer of this utility model.

[0032] Appendix Figure 6 This is a schematic diagram of the light source module of this utility model.

[0033] The following are the labels in the attached diagram: 1. Body; 11. Isolation plate; 12. "L-shaped" bracket; 121. Vertical bracket; 122. Crossbeam; 123. Reinforcing rib; 13. Baffle; 14. Radiator; 15. Fan; 16. Opening; 17. Door; 18. Touch screen; 19. USB port; 2. Sample placement tray; 3. X-axis module; 4. Y-axis module; 5. Light source module; 51. Light source; 52. Heat sink housing; 53. Focusing lens; 54. Collimating lens; 6. Spectrometer; 7. Fiber optic probe; 71. Input fiber optic; 72. Output fiber optic; 73. Probe section; 8. Shutter module; 81. Light shield; 82. Drive mechanism; 9. Industrial computer. Detailed Implementation

[0034] To make the objectives, technical solutions, and advantages of this utility model clearer, the technical solutions of the embodiments of this utility model will be clearly and completely described below with reference to the accompanying drawings. The same reference numerals in the drawings represent the same components. It should be noted that the described embodiments are only some, not all, of the embodiments of this utility model. All other embodiments obtained by those skilled in the art based on the described embodiments of this utility model without creative effort are within the scope of protection of this utility model.

[0035] Unless otherwise defined, the technical or scientific terms used herein shall have the ordinary meaning as understood by one of ordinary skill in the art to which this invention pertains. The terms "first," "second," and similar words used in this utility model specification and claims do not indicate any order, quantity, or importance, but are merely used to distinguish different components. Terms such as "comprising" or "including" mean that the element or object preceding the word encompasses the elements or objects listed following the word and their equivalents, without excluding other elements or objects. Terms such as "connected" or "linked" are not limited to physical or mechanical connections, but can include electrical connections, whether direct or indirect. Terms such as "upper," "lower," "left," and "right" are used only to indicate relative positional relationships; when the absolute position of the described object changes, the relative positional relationship may also change accordingly.

[0036] like Figures 1-3 As shown, this utility model provides a highly integrated nano-optical sensing array that can be used for SPR detection. It includes a body 1, and the body 1 is provided with a sample placement tray 2, an X-axis module 3, a Y-axis module 4, a light source module 5, a spectrometer 6, and an optical fiber probe 7.

[0037] The sample placement tray 2 includes a gold reference position and multiple sample positions for placing the gold reference and the sample to be tested. The X-axis module 3 is used to control the movement of the sample placement tray 2 along the X-axis. The Y-axis module 4 is used to control the movement of the sample placement tray 2 and the X-axis module 3 along the Y-axis. The light source module 5 is used to provide a light source. The fiber optic probe 7 is located on the upper side of the sample placement tray 2. The fiber optic probe 7 includes an input fiber 71, an output fiber 72, and a probe section 73 connecting the input fiber 71 and the output fiber 72. The input fiber 71 is connected to the light source module 5, and the output fiber 72 is connected to the spectrometer 6. The light emitted by the light source module 5 is transmitted to the probe section 73 via the input fiber 71 and is emitted from the probe section 73. The emitted light is reflected by the sample surface and then incident on the probe section 73, and is transmitted to the spectrometer 6 via the output fiber 72.

[0038] This invention encapsulates the light source module 5, spectrometer 6, fiber optic probe 7, and X-axis and Y-axis modules 3 and 4 (for controlling the movement of the sample placement tray 2) within the body 1, avoiding external light interference and mechanical vibration, thus improving its resistance to environmental interference and the stability of signal acquisition. The compact, integrated design also enhances its portability. The sample placement tray 2 integrates a gold reference site and multiple sample sites, enabling non-destructive continuous detection of multiple sample sites without the need for manual target replacement, reducing operational errors and ensuring measurement consistency and accuracy. The sample placement tray 2 can integrate a 10*10 3D nano-metal sample point array, utilizing the localized surface plasmon resonance effect and the interaction between nanoscale structures and light to achieve highly sensitive detection of reflectivity using nano-optical sensing technology.

[0039] Furthermore, the light source module 5 includes a light source 51, and a lens group is provided on the optical path channel between the light source 51 and the input optical fiber 71. A heat dissipation shell 52 is provided on the outer periphery of the light source 51 to absorb the heat of the light source 51 and conduct it away. A fan 15 can also be provided on one side of the heat dissipation shell 52 to further improve the heat dissipation effect of the light source 51 and prevent the light source 51 from overheating, which could lead to wavelength drift, reduced efficiency, or shortened lifespan.

[0040] Furthermore, the lens group includes a collimating lens 53 and a focusing lens 54 arranged sequentially from the light source 51 side to the input optical fiber 71 side. The collimating lens 53 converts the light beam emitted by the light source 51 into a parallel light beam, and the focusing lens 54 refocuses the parallel light beam onto the end face of the input optical fiber 71.

[0041] Furthermore, a shutter module 8 is provided between the focusing lens 54 and the collimating lens 53. The shutter module 8 includes a light-shielding plate 81 and a drive mechanism 82 for controlling the movement or rotation of the light-shielding plate 81. In this embodiment, the drive mechanism 82 can be a cylinder or a push rod motor to control the translation of the light-shielding plate 81. The shutter module 8 can cut off the light source path, protecting the sample from prolonged irradiation (especially photosensitive samples) and serving as a dark-field calibration and white-dark reference. Moreover, the collimating lens 53 of this invention generates parallel light in front, the shutter module 8 is placed in the parallel light path, and the focusing lens 54 couples into the fiber optic probe 7, resulting in high light energy utilization and avoiding tilt-induced shading losses.

[0042] Furthermore, an isolation plate 11 is provided between the X-axis module 3 and the Y-axis module 4 for electromagnetic isolation. The isolation plate 11 has a moving channel for the slide of the Y-axis module 4 to move. Preferably, parallel slide rails are provided on both sides of the Y-axis module 4, and the X-axis module 3 is slidably connected to the slide rails, improving the movement stability of the X-axis module 3 and the sample placement tray 2. Parallel slide rails are provided on both sides of the X-axis module 3, and the sample placement tray 2 is slidably connected to the slide rails, improving the movement stability of the sample placement tray 2, thereby enhancing the stability of signal collection.

[0043] Furthermore, the probe part 73 of the fiber optic probe 7 is mounted on the isolation plate 11 via an "L-shaped" bracket 12. The "L-shaped" bracket 12 includes a vertical frame 121 and a crossbeam 122 mounted on the upper side of the vertical frame 121. A reinforcing rib 123 can also be provided between the crossbeam 122 and the vertical frame 121. The probe part 73 of the fiber optic probe 7 is located at the end of the crossbeam 122 away from the vertical frame, which provides sufficient space for the sample placement tray 2 while ensuring the stability of the fixed probe part 73 of the fiber optic probe 7.

[0044] Furthermore, a baffle 13 is also provided inside the body 1, which separates the spectrometer 6 and the light source module 5 from the fiber optic probe 7, the X-axis module 3, and the Y-axis module 4 into two spaces. The baffle 13 can prevent the light from the sensor lamp of the spectrometer 6 from affecting the accuracy of the data.

[0045] Furthermore, the body 1 is also equipped with a heat sink 14 and a fan 15. The heat sink 14 can be located on the lower side of the spectrometer 6, and multiple fans 15 can be provided to improve the heat dissipation effect. An opening 16 for placing samples is provided at the sample placement tray 2 position of the body 1, and a door 17 is movable at the opening position to facilitate sample placement.

[0046] Furthermore, an industrial control computer 9 is installed inside the body 1, which is connected to the X-axis module 3, Y-axis module 4, light source module 5, spectrometer 6, and shutter module 8, to automatically control the operation of each module.

[0047] Furthermore, the machine body 1 is also equipped with a touch screen 18 and a USB port 19 connected to the industrial control computer 9. The touch screen 18 is easy to operate, and the USB port 19 is easy to connect to a computer and export data.

[0048] The operation steps of this utility model include:

[0049] (1) Connect the power supply and the light source will automatically turn on;

[0050] (2) Click the “Change Sample” button on the software, and the X-axis module 3 and Y-axis module 4 will start running, thereby controlling the movement of the sample placement tray 2, so that the sample placement tray 2 is moved to the appropriate position, and then the hatch 17 is opened. After placing or changing the sample, the hatch 17 is closed.

[0051] (3) Click the “Reference” button on the software, and the X-axis module 3 and Y-axis module 4 will start running, thereby controlling the movement of the sample placement disk 2, so that the gold reference position on the sample placement disk 2 will automatically move to the lower side of the probe part 73 of the fiber optic probe 7, and perform automatic integration, and open or close the shutter module 8 to save the white and dark reference.

[0052] (4) Select the sample point to be tested in the table displayed on the software, click the “Start” button, and the X-axis module 3 and Y-axis module 4 will control the sample placement disk 2 to move according to the selected point on the software, so that the corresponding sample position moves to the lower side of the probe part 73 of the fiber optic probe 7, and the spectrometer 6 collects data.

[0053] (5) During this period, if you want to change / add samples, click the "Stop" button and the spectrometer 6 will stop collecting data. Click the "Change Sample" button and the X-axis module 3 and Y-axis module 4 will move the sample placement tray 2 to a suitable position to facilitate adding / changing samples.

[0054] (6) Click the “Stop” button in the software to stop the spectrometer 6 from acquiring data.

[0055] Those skilled in the art should understand that the specific embodiments described above are merely examples and not limitations. Various modifications, combinations, partial combinations, and substitutions can be made to the embodiments of this utility model according to design requirements and other factors, as long as they are within the scope of the appended claims or their equivalents, and thus fall within the scope of the rights to be protected by this utility model.

Claims

1. A high-integration nanophotonic sensing array comprising a body, characterized in that, The machine body is equipped with: The sample placement tray includes a gold reference position and multiple sample positions; The X-axis module is used to control the movement of the sample placement tray along the X-axis. The Y-axis module is used to control the sample placement tray, and the X-axis module moves along the Y-axis direction. The light source module is used to provide the light source; Spectrometer; An optical fiber probe is located on the upper side of the sample placement tray. The optical fiber probe includes an input optical fiber, an output optical fiber, and a probe section connecting the input optical fiber and the output optical fiber. The input optical fiber is connected to the light source module, and the output optical fiber is connected to the spectrometer. The light emitted by the light source module is transmitted to the probe section via the input optical fiber and then emitted from the probe section. The emitted light is reflected by the sample surface and then enters the probe section, and is transmitted to the spectrometer via the output optical fiber.

2. The high-integration nanophotonic sensing array of claim 1, wherein, The light source module includes a light source, a lens group is provided on the optical path channel between the light source and the input optical fiber, and a heat dissipation shell is provided on the outer periphery of the light source.

3. The high-integration nanophotonic sensing array of claim 2, wherein, The lens group includes a collimating lens and a focusing lens arranged sequentially from the light source side to the input optical fiber side.

4. The high-integration nanophotonic sensor array of claim 3, wherein, A shutter module is provided between the focusing lens and the collimating lens. The shutter module includes a light-blocking plate and a drive mechanism for controlling the movement or rotation of the light-blocking plate.

5. The highly integrated nanophotonic sensor array of claim 1, wherein, An isolation plate is provided between the X-axis module and the Y-axis module, and the isolation plate is provided with a moving channel for the slide of the Y-axis module to move.

6. The high-integration nanophotonic sensor array of claim 5, wherein, The probe section of the optical fiber probe is mounted on the isolation plate via an "L-shaped" bracket.

7. The highly integrated nanophotonic sensor array of claim 1, wherein, The machine body is also equipped with a baffle that separates the spectrometer, light source module and fiber optic probe, X-axis module and Y-axis module into two spaces.

8. The highly integrated nanophotonic sensor array of claim 1, wherein, The machine body is also equipped with a radiator and a fan; the sample placement tray of the machine body is provided with an opening for placing samples, and a door is movably installed at the opening.

9. The highly integrated nanophotonic sensor array of claim 3, wherein, The machine body contains an industrial control computer connected to the drive mechanisms of the light source module, X-axis module, Y-axis module, and shutter module.

10. The highly integrated nanophotonic sensor array of claim 9, wherein, The machine body is also equipped with a touch screen display and a USB port that connect to an industrial control computer.

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