Stem cell intravenous return mouse fixation device
By designing an adjustable fixation device, the problem of poor adaptability of existing mouse fixation devices was solved, achieving stable fixation of mice of different sizes and improving the effect of tail vein injection in mice.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- BAIOPAI (TIANJIN) BIOTECHNOLOGY CO LTD
- Filing Date
- 2025-06-10
- Publication Date
- 2026-06-12
Smart Images
Figure CN224345033U_ABST
Abstract
Description
Technical Field
[0001] This application relates to the field of mouse fixation devices, and more specifically, to a mouse fixation device for intravenous infusion of stem cells. Background Technology
[0002] In stem cell therapy research, tail vein injection in mice is a commonly used technique. Before tail vein injection, the mouse tail needs to be fixed. However, simply fixing the mouse tail allows the mouse's trunk to move, which can affect the intravenous injection process. Existing mouse fixation devices, while able to fix the mouse, are difficult to adjust flexibly according to different mouse sizes, resulting in poor adaptability. To address this, we propose a stem cell intravenous reinfusion mouse fixation device. Utility Model Content
[0003] To overcome the above shortcomings, this application provides a stem cell intravenous infusion mouse fixation device, which aims to improve the problem that existing mouse fixation devices are inconvenient for fixing mice of different sizes.
[0004] This application provides a stem cell intravenous infusion mouse fixation device, including a base, a lifting mechanism installed on the top of the base, an adjustment component installed on the side wall of the lifting mechanism, an assembly plate installed on the adjustment component, a head fixation component, a torso fixation component and a slide rail installed on the assembly plate, and a tail fixation component connected to the slide rail.
[0005] In one specific implementation, the lifting mechanism includes a vertical column fixedly installed on the top of the base, a lifting tube slidably sleeved on the vertical column, an insert rod slidably passing through the side wall of the lifting tube, the insert rod being inserted into the vertical column, and an adjusting member being installed on the side wall of the lifting tube.
[0006] In one specific implementation, a limiting groove is formed on the side wall of the vertical column, and a limiting block is fixedly installed on the inner wall of the lifting pipe. The limiting block is slidably disposed in the limiting groove, and the insertion rod slides through the limiting block.
[0007] In one specific implementation, a plurality of insertion holes are provided on the inner wall of the limiting groove, one end of the insertion rod is inserted into one of the insertion holes, and a spring is connected between the head of the insertion rod and the side wall of the lifting tube, the spring being slidably sleeved on the insertion rod.
[0008] In one specific implementation, the adjusting component includes a rotating shaft and a fixing block. The rotating shaft is rotatably connected to the side wall of the lifting tube, and the fixing block is fixedly installed on the side wall of the lifting tube. A turbine is fixedly sleeved on the rotating shaft, and a worm gear rotatably passes through the fixing block. The worm gear drives the turbine. A bracket is also fixedly sleeved on the rotating shaft, and the mounting plate is fixedly connected to the bracket.
[0009] In one specific implementation, the head fastener includes a longitudinally arranged frame, a threaded rod rotatably connected to the side wall of the frame, a slider threaded onto the threaded rod, and a first Velcro assembly mounted on the top of the slider.
[0010] In one specific implementation, the torso fastener includes two second Velcro straps, which are fixedly connected to the middle portion of the assembly plate.
[0011] In one specific implementation, the tail fixing member includes a movable seat slidably sleeved on the slide rail, a tightening screw threaded through the side wall of the movable seat, and a fixing ring fixedly installed on its top.
[0012] The beneficial effects of this application are as follows: By installing a lifting mechanism on the base, an adjusting component is installed on the side wall of the lifting mechanism, and an assembly plate is installed on the adjusting component. The lifting mechanism can adjust the height of the assembly plate, while the adjusting component can adjust the angle of the assembly plate. A frame is installed on the assembly plate, and a threaded rod is rotatably threaded through the side wall of the frame. A slider is threadedly sleeved on the threaded rod, and a first Velcro assembly for fixing the mouse's head is installed on the top of the slider. The first Velcro assembly is adjustable to accommodate different mouse sizes. A second Velcro assembly for fixing the mouse's torso is also installed on the top of the assembly plate. In addition, a slide rail is installed on the top of the assembly plate, and a movable seat is installed on the slide rail. A fixing ring is installed on the top of the movable seat, and the fixing ring can be adjusted according to the mouse's size, thereby achieving the purpose of easily fixing mice of different sizes. Attached Figure Description
[0013] To more clearly illustrate the technical solutions of the embodiments of this application, the drawings used in the embodiments will be briefly introduced below. It should be understood that the following drawings only show some embodiments of this application and should not be regarded as a limitation of the scope. For those skilled in the art, other related drawings can be obtained from these drawings without creative effort.
[0014] Figure 1 This is a first-view structural schematic diagram of the stem cell intravenous infusion mouse fixation device provided in the embodiments of this application;
[0015] Figure 2A second-view structural schematic diagram of the stem cell intravenous infusion mouse fixation device provided in the embodiments of this application;
[0016] Figure 3 A side view of the stem cell intravenous infusion mouse fixation device provided in an embodiment of this application;
[0017] Figure 4 A schematic diagram of the assembly plate structure of the stem cell intravenous infusion mouse fixation device provided in the embodiments of this application;
[0018] Figure 5 for Figure 2 A magnified view of a section at point A in the middle;
[0019] Figure 6 for Figure 4 A magnified view of a section at point B in the middle.
[0020] In the diagram: 10-base; 20-lifting mechanism; 210-vertical column; 220-lifting tube; 230-spring; 240-insertion rod; 250-limiting groove; 260-limiting block; 270-insertion hole; 30-adjusting component; 310-rotating shaft; 320-fixing block; 330-turbine; 340-worm gear; 350-bracket; 40-assembly plate; 50-head fixing component; 510-frame; 520-threaded rod; 530-slider; 540-first Velcro assembly; 60-torso fixing component; 70-slide rail; 80-tail fixing component; 810-moving seat; 820-clamping screw; 830-fixing ring. Detailed Implementation
[0021] The technical solutions in the embodiments of this application will now be described with reference to the accompanying drawings.
[0022] Please see Figure 1-6 This application provides a mouse fixation device for intravenous infusion of stem cells, including a base 10, a lifting mechanism 20 installed on the top of the base 10, an adjustment component 30 installed on the side wall of the lifting mechanism 20, an assembly plate 40 installed on the adjustment component 30, a head fixation component 50, a trunk fixation component 60 and a slide rail 70 installed on the assembly plate 40, and a tail fixation component 80 connected to the slide rail 70. Specifically, in the process of stem cell research, tail vein injection of mice is a common technique. Before intravenous injection, the mouse needs to be fixed. The mouse is placed on the assembly plate 40. The head fixation component 50 can fix the head of the mouse, the trunk fixation component 60 can fix the trunk of the mouse, and the tail fixation component 80 can fix the tail of the mouse. At the same time, the tail fixation component 80 can move on the slide rail 70 to fix the tail of mice of different sizes.
[0023] See Figure 2The lifting mechanism 20 includes a vertical column 210 fixedly installed on the top of the base 10. A lifting tube 220 is slidably sleeved on the vertical column 210. A plug rod 240 is slidably passed through the side wall of the lifting tube 220. The plug rod 240 is inserted into the vertical column 210. An adjusting member 30 is installed on the side wall of the lifting tube 220. When set, the lifting tube 220 can move on the vertical column 210. By setting the plug rod 240, the lifting tube 220 can be fixed. Then, the height of the assembly plate 40 can be adjusted by the lifting tube 220, so as to adjust the height of the assembly plate 40 according to actual needs, which is helpful for the intravenous injection process of mice. The adjusting member 30 can adjust the angle of the assembly plate 40, so as to adjust the overall angle of the mouse, which is convenient for intravenous injection in the tail vein of the mouse.
[0024] See Figure 5 A limiting groove 250 is formed on the side wall of the vertical column 210. A limiting block 260 is fixedly installed on the inner wall of the lifting tube 220. The limiting block 260 is slidably disposed within the limiting groove 250, allowing it to slide within the groove. The limiting block 260 limits the lifting tube 220, preventing it from rotating on the vertical column 210. The insertion rod 240 slides through the limiting block 260. Furthermore, the limiting groove 250... The inner wall of the device 0 has several insertion holes 270. One end of the insertion rod 240 is inserted into one of the insertion holes 270. The insertion rod 240 cooperates with the insertion hole 270 to fix the lifting tube 220. A spring 230 is connected between the head of the insertion rod 240 and the side wall of the lifting tube 220. The spring 230 is slidably sleeved on the insertion rod 240 and limits the insertion rod 240 so that one end of the insertion rod 240 will not fall out of the insertion hole 270.
[0025] See Figure 1 and 3 The adjusting component 30 includes a rotating shaft 310 and a fixing block 320. The rotating shaft 310 is rotatably connected to the side wall of the lifting pipe 220, and the fixing block 320 is fixedly installed on the side wall of the lifting pipe 220. A turbine 330 is fixedly sleeved on the rotating shaft 310, and a worm gear 340 rotatably passes through the fixing block 320. The worm gear 340 drives the turbine 330. A bracket 350 is also fixedly sleeved on the rotating shaft 310, and the mounting plate 40 is fixedly connected to the bracket 350. In a specific setting, a rotating handle is fixedly installed at one end of the worm gear 340. By rotating the rotating handle, the worm gear 340 can be easily rotated, and the worm gear 340 can drive the turbine 330 to rotate. At the same time, the worm gear 340 has a locking function for the turbine 330 so that the mounting plate 40 can be fixed after the angle is adjusted.
[0026] See Figure 4The head fixing component 50 includes a longitudinally arranged frame 510. A threaded rod 520 is rotatably connected to the side wall of the frame 510. Specifically, one end of the threaded rod 520 is rotatably connected to one side wall of the frame 510, and the other end of the threaded rod 520 rotatably passes through the other side wall of the frame 510. A slider 530 is threaded onto the threaded rod 520. A first Velcro group 540 is installed on the top of the slider 530. When set, the first Velcro group 540 includes two first Velcros for fixing the mouse head.
[0027] See Figure 4 The torso fixing member 60 includes two second Velcro straps, which are fixedly connected to the middle part of the assembly plate 40. The two second Velcro straps fix the mouse torso. Further, the tail fixing member 80 includes a movable seat 810 that is slidably sleeved on the slide rail 70. A tightening screw 820 is threaded through the side wall of the movable seat 810. By rotating the tightening screw 820, the movable seat 810 can be fixed on the slide rail 70. Specifically, both the movable seat 810 and the slide rail 70 are designed in a dovetail shape, which can limit the movement of the movable seat 810. A fixing ring 830 is fixedly installed on the top of the movable seat 810. The fixing ring 830 can be sleeved on the tail of the mouse to fix the tail. The fixing ring 830 can be set according to the specific shape of the mouse tail.
[0028] When using this stem cell intravenous infusion mouse fixation device: Place the mouse on the assembly plate 40, with the mouse's torso positioned between two second Velcro straps. Secure the mouse's torso with the two second Velcro straps. Then, rotate the threaded rod 520, which drives the slider 530 to move on the frame 510, causing the slider 530 to move below the mouse's head. Simultaneously, two first Velcro straps are positioned on either side of the mouse's head, securing the mouse's head with the two first Velcro straps. Finally, push the movable seat 810, aligning the fixing ring 830 with the mouse's tail, allowing the mouse's tail to pass through the fixing ring 830. Push the fixing ring 830 to move it until it secures the mouse's tail. Rotate the tightening screw 820 to fix the movable seat 810, allowing intravenous injection to be performed on the mouse's tail.
[0029] It should be noted that the specific model specifications of the turbine 330 and worm gear 340 need to be determined based on the actual specifications of the device. The specific selection calculation method adopts the existing technology in this field, so it will not be described in detail here.
[0030] The above description is merely an embodiment of this application and is not intended to limit the scope of protection of this application. Various modifications and variations can be made to this application by those skilled in the art. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of this application should be included within the scope of protection of this application. It should be noted that similar reference numerals and letters in the following figures indicate similar items; therefore, once an item is defined in one figure, it does not need to be further defined and explained in subsequent figures.
Claims
1. A mouse fixation device for intravenous infusion of stem cells, characterized in that, Includes a base (10), a lifting mechanism (20) is installed on the top of the base (10), an adjusting component (30) is installed on the side wall of the lifting mechanism (20), an assembly plate (40) is installed on the adjusting component (30), a head fixing component (50), a torso fixing component (60) and a slide rail (70) are installed on the assembly plate (40), and a tail fixing component (80) is connected to the slide rail (70).
2. The stem cell intravenous infusion mouse fixation device according to claim 1, characterized in that, The lifting mechanism (20) includes a vertical column (210) fixedly installed on the top of the base (10), a lifting tube (220) is slidably sleeved on the vertical column (210), a plug rod (240) is slidably passed through the side wall of the lifting tube (220), the plug rod (240) is inserted into the vertical column (210), and the adjusting member (30) is installed on the side wall of the lifting tube (220).
3. The stem cell intravenous infusion mouse fixation device according to claim 2, characterized in that, A limiting groove (250) is provided on the side wall of the vertical column (210), and a limiting block (260) is fixedly installed on the inner wall of the lifting pipe (220). The limiting block (260) is slidably disposed in the limiting groove (250), and the insert rod (240) slides through the limiting block (260).
4. The stem cell intravenous infusion mouse fixation device according to claim 3, characterized in that, The inner wall of the limiting groove (250) is provided with a plurality of insertion holes (270). One end of the insertion rod (240) is inserted into one of the insertion holes (270). A spring (230) is connected between the head of the insertion rod (240) and the side wall of the lifting tube (220). The spring (230) is slidably sleeved on the insertion rod (240).
5. The stem cell intravenous infusion mouse fixation device according to claim 2, characterized in that, The adjusting component (30) includes a rotating shaft (310) and a fixing block (320). The rotating shaft (310) is rotatably connected to the side wall of the lifting tube (220). The fixing block (320) is fixedly installed on the side wall of the lifting tube (220). A turbine (330) is fixedly sleeved on the rotating shaft (310). A worm gear (340) rotatably passes through the fixing block (320). The worm gear (340) drives the turbine (330). A bracket (350) is also fixedly sleeved on the rotating shaft (310). The mounting plate (40) is fixedly connected to the bracket (350).
6. The stem cell intravenous infusion mouse fixation device according to claim 1, characterized in that, The head fixing member (50) includes a frame (510) arranged longitudinally, a threaded rod (520) is rotatably connected to the side wall of the frame (510), a slider (530) is threaded on the threaded rod (520), and a first Velcro assembly (540) is installed on the top of the slider (530).
7. The stem cell intravenous infusion mouse fixation device according to claim 1, characterized in that, The torso fastener (60) includes two second Velcro straps, which are fixedly connected to the middle part of the assembly plate (40).
8. The stem cell intravenous infusion mouse fixation device according to claim 1, characterized in that, The tail fixing member (80) includes a movable seat (810) that is slidably sleeved on the slide rail (70), and a tightening screw (820) is threaded through the side wall of the movable seat (810), and a fixing ring (830) is fixedly installed on its top.