occluder

Abstract

This utility model relates to an occlusion device, including an occlusion mesh and a flow-blocking structure disposed within the inner cavity of the occlusion mesh. The flow-blocking structure includes a first flow-blocking portion and a second flow-blocking portion arranged sequentially along the axial direction. The first flow-blocking portion includes a first radial flow-blocking membrane, a first circumferential flow-blocking membrane, and a second radial flow-blocking membrane arranged sequentially along the axial direction. The first circumferential flow-blocking membrane extends circumferentially to form a first tubular structure, with openings at both axial ends. The second radial flow-blocking membrane covers the opening in the first tubular structure closer to the second occlusion disc. Along the axial direction, there is a gap between the second radial flow-blocking membrane and the second flow-blocking portion. There is no flow-blocking membrane within the gap, and the interval between the gaps is variable. The occlusion device of this utility model has a better occlusion effect and can effectively reduce the problem of poor intraoperative formation of the occlusion disc caused by the difficulty of the flow-blocking membrane following the deformation of the occlusion mesh.

Description

Technical Field

[0001] This utility model relates to the field of medical device technology, and in particular to an occluder. Background Technology

[0002] Congenital heart disease includes atrial septal defect (ASD), ventricular septal defect (VSD), and patent ductus arteriosus (PDA). A healthy heart consists of left and right atria and ventricles. The atrial septum separates the atria, and the ventricular septum separates the ventricles. The aorta, which forms the systemic circulation, connects the left atrium and left ventricle, while the pulmonary artery, which forms the pulmonary circulation, connects the right atrium and right ventricle. The aorta and pulmonary artery are not connected. An ASD is a defect in the atrial septum that allows the left and right atria to communicate; a VSD is a defect in the ventricular septum that allows the left and right ventricles to communicate; and a PDA is a defect where the aorta and pulmonary artery are connected.

[0003] The therapeutic principle of a cardiac occluder is as follows: the occluder is radially contracted and loaded into a delivery device, which then delivers it to the patient's cardiac defect. After release, the occluder blocks the defect, causing blood flowing to the occluder's surface to thrombose and subsequently organize into fibrous tissue. Surrounding tissue also grows inwards, eventually completing endothelialization of the occluder and the fibrous tissue within it, thereby repairing the cardiac defect. The occluder mainly consists of an occlusive frame and a radially positioned choke membrane. When the occluder does not adhere properly to the defect, residual shunts can easily occur, leading to complications. Utility Model Content

[0004] Based on this, the present invention proposes a sealing device that has a good sealing effect.

[0005] An occlusion device, comprising:

[0006] An occlusion mesh with an inner cavity includes a first occlusion disc and a second occlusion disc spaced apart axially in the occlusion device, and a waist portion located between the first occlusion disc and the second occlusion disc. The first axial end of the waist portion is connected to the first occlusion disc, and the second axial end of the waist portion is connected to the second occlusion disc.

[0007] A flow-blocking structure is disposed within the inner cavity of the plugging mesh. The flow-blocking structure includes a first flow-blocking portion and a second flow-blocking portion arranged sequentially along the axial direction. The first flow-blocking portion includes a first radial flow-blocking membrane, a first circumferential flow-blocking membrane, and a second radial flow-blocking membrane arranged sequentially along the axial direction. The first radial flow-blocking membrane is fixedly connected to the first plugging disc and extends radially when the plugging device is in a radially deployed state. The second radial flow-blocking membrane is fixedly connected to the waist portion and extends radially when the plugging device is in a radially deployed state. The first circumferential flow-blocking membrane extends circumferentially to form a first tubular structure. Both ends of the first tubular structure have openings. The second radial flow-blocking membrane covers the opening of the first tubular structure that is closer to the second plugging disc. Along the axial direction of the plugging device, there is a gap between the first circumferential flow-blocking membrane and the second flow-blocking portion. There is no flow-blocking membrane in the gap, and the interval distance of the gap is variable.

[0008] In one embodiment, the second flow-blocking portion includes a third radial flow-blocking membrane, which is fixedly connected to the second sealing disc and extends radially when the sealing device is in a radially deployed state.

[0009] In one embodiment, the second flow-blocking portion further includes a second circumferential flow-blocking membrane, which is partially or completely fixed within the waist portion. The second circumferential flow-blocking membrane extends circumferentially to form a second tubular structure. Both axial ends of the second tubular structure have openings, and the opening closer to the first sealing plate in the second tubular structure is an open structure.

[0010] In one embodiment, the axial end of the first tubular structure closer to the first radial flow-blocking membrane is directly fixedly connected to the first radial flow-blocking membrane; or, the first flow-blocking portion further includes a first annular flow-blocking membrane, which is located within the first sealing disc and extends radially along the sealing device when the sealing device is in a radially deployed state. The first annular flow-blocking membrane includes a first inner ring edge and a first outer ring edge, the first inner ring edge being fixedly connected to the axial end of the first tubular structure closer to the first radial flow-blocking membrane, and the first outer ring edge being fixedly connected to the first radial flow-blocking membrane.

[0011] In one embodiment, the axial end of the second tubular structure closer to the second radial flow-blocking membrane is directly fixedly connected to the second radial flow-blocking membrane; or, the second flow-blocking portion further includes a second annular flow-blocking membrane, which is located within the second sealing disc and extends radially along the sealing device when the sealing device is in a radially deployed state. The second annular flow-blocking membrane includes a second inner ring edge and a second outer ring edge. The second inner ring edge is fixedly connected to the axial end of the second tubular structure closer to the third radial flow-blocking membrane, and the second outer ring edge is fixedly connected to the third radial flow-blocking membrane.

[0012] In one embodiment, the first flow-blocking portion further includes a first annular flow-blocking membrane located within the first sealing disc. The first annular flow-blocking membrane includes a first annular unit and a second annular unit, both annular and extending radially along the sealing device. The inner edge of the first annular unit is fixedly connected to the axial end of the first tubular structure closer to the first radial flow-blocking membrane. The outer edge of the first annular unit is fixedly connected to the inner edge of the second annular unit, and the outer edge of the second annular unit is fixedly connected to the outer edge of the first radial flow-blocking membrane. The first radial flow-blocking membrane is an integral structure; and / or, the second flow-blocking portion includes a third radial flow-blocking membrane, a second annular flow-blocking membrane, and a second circumferential flow-blocking membrane, the second circumferential flow-blocking membrane being partially or completely fixed within the waist portion, the second circumferential flow-blocking membrane extending circumferentially to form a second tubular structure, the third radial flow-blocking membrane and the second annular flow-blocking membrane being located within the second sealing disk, the second annular flow-blocking membrane including a second inner ring edge and a second outer ring edge, the second inner ring edge being fixedly connected to the axial end of the second tubular structure closer to the third radial flow-blocking membrane, and the second outer ring edge being fixedly connected to the outer edge of the third radial flow-blocking membrane.

[0013] In one embodiment, the first occlusion disc includes a first distal disc and a first proximal disc, and the first radial flow-blocking membrane is fixedly connected to the first distal disc via a first fixing part, the first fixing part surrounding the central axis of the occluder and located between the central axis of the occluder and the edge of the first occlusion disc; and / or, the second occlusion disc includes a second distal disc and a second proximal disc, the second flow-blocking part includes a third radial flow-blocking membrane, the third radial flow-blocking membrane being fixedly connected to the second proximal disc via a second fixing part, the second fixing part surrounding the central axis of the occluder and located between the central axis of the occluder and the edge of the second occlusion disc.

[0014] In one embodiment, the first occlusion disc includes a first distal disc and a first proximal disc, the first radial flow-blocking membrane is fixedly connected to the first distal disc via a first fixing part, the first fixing part being an annular structure formed by stitches, and the ratio between the minimum radial distance from the first fixing part to the edge of the first occlusion disc and the radial dimension of the first occlusion disc is in the range of 1 / 8 to 3 / 8; and / or, the second occlusion disc includes a second distal disc and a second proximal disc, the second flow-blocking part includes a third radial flow-blocking membrane, the third radial flow-blocking membrane is fixedly connected to the second proximal disc via a second fixing part, the second fixing part being an annular structure formed by stitches, and the ratio between the minimum radial distance from the second fixing part to the edge of the second occlusion disc and the radial dimension of the second occlusion disc is in the range of 1 / 8 to 3 / 8.

[0015] In one embodiment, the first flow-blocking portion further includes a first annular flow-blocking membrane located within the first sealing disc. The first annular flow-blocking membrane includes a first annular unit and a second annular unit, both annular and extending radially along the sealing device. The inner edge of the first annular unit is fixedly connected to the axial end of the first tubular structure closer to the first radial flow-blocking membrane. The outer edge of the first annular unit is fixedly connected to the inner edge of the second annular unit, and the outer edge of the second annular unit is fixedly connected to the first radial flow-blocking membrane. The first annular unit, the second radial flow-blocking membrane, and the first circumferential flow-blocking membrane are connected in a fixed manner. The flow membrane is an integral structure; and / or, the second flow-blocking portion includes a third radial flow-blocking membrane, a second annular flow-blocking membrane, and a second circumferential flow-blocking membrane, the second circumferential flow-blocking membrane being partially or completely fixed within the waist portion, the second circumferential flow-blocking membrane extending circumferentially to form a second tubular structure, the third radial flow-blocking membrane and the second annular flow-blocking membrane being located within the second sealing disk, the second annular flow-blocking membrane including a second inner ring edge and a second outer ring edge, the second inner ring edge being fixedly connected to the axial end of the second tubular structure closer to the third radial flow-blocking membrane, the second outer ring edge being fixedly connected to the third radial flow-blocking membrane, and the second annular flow-blocking membrane and the second circumferential flow-blocking membrane being an integral structure.

[0016] In one embodiment, the outer edge of the second radial flow-blocking membrane is stitched and fixedly connected to the waist portion; and / or, the second flow-blocking portion includes a second circumferential flow-blocking membrane, the second circumferential flow-blocking membrane being partially or completely fixed within the waist portion, the second circumferential flow-blocking membrane extending circumferentially to form a second tubular structure, the axial end of the second tubular structure closer to the first sealing disc being stitched and fixedly connected to the waist portion.

[0017] In one embodiment, the occluder is an absorbable occluder, which further includes an end cap, a plug, and a locking element. The occlusion mesh is woven from braided wires to form a mesh structure. The end cap is used to gather one axial end of the occlusion mesh, and the plug is used to gather the other axial end of the occlusion mesh. The locking element is inserted into the inner cavity of the occlusion mesh, and one axial end of the locking element is fixedly connected to the end cap, while the other axial end of the locking element is detachably connected to the plug.

[0018] In one embodiment, when the plug is in a radially deployed state, the maximum axial spacing distance of the interval section is 0~3mm.

[0019] The aforementioned plugging device includes a plugging mesh and a flow-blocking structure disposed within the inner cavity of the plugging mesh. The flow-blocking structure includes a first flow-blocking portion and a second flow-blocking portion arranged sequentially along the axial direction. The first flow-blocking portion includes a first radial flow-blocking membrane, a first circumferential flow-blocking membrane, and a second radial flow-blocking membrane arranged sequentially along the axial direction. The first radial flow-blocking membrane extends radially and is fixedly connected within the first plugging disk. The second radial flow-blocking membrane extends radially and is fixedly connected within the waist portion. The first circumferential flow-blocking membrane extends circumferentially to form a first tubular structure. Both axial ends of the first tubular structure have openings. The second radial flow-blocking membrane covers the opening of the first tubular structure closer to the second plugging disk. Along the axial direction, there is a gap between the second radial flow-blocking membrane and the second flow-blocking portion. There is no flow-blocking membrane within the gap, and the interval distance of the gap is variable. By setting a first circumferential choke membrane and a second radial choke membrane in the occluder, with the second radial choke membrane positioned within the waist and covering the opening of the first tubular structure of the first circumferential choke membrane closer to the second occlusion disc, blood flow passing through the waist can be blocked radially and axially, thus achieving a better occlusion effect. In addition, due to the presence of the septum, the first circumferential choke membrane does not cover the entire waist, which can effectively reduce the problem of poor intraoperative occlusion disc formation caused by the choke membrane's difficulty in following the deformation of the occlusion mesh. Attached Figure Description

[0020] Figure 1 This is a schematic diagram of the sealing device in a radially expanded state in one embodiment of the present invention;

[0021] Figure 2 for Figure 1 A schematic diagram of the blocking mesh structure of the middle blocker (the flow-blocking structure is not shown).

[0022] Figure 3 for Figure 1 A schematic diagram of the structure of the central plug (the mesh of the plugging net is not shown);

[0023] Figure 4This is a schematic diagram of the structure of the first radial flow-blocking membrane and its stitching position in one embodiment of the present invention;

[0024] Figure 5 This is a schematic diagram of the third radial flow-blocking membrane and its stitching position in one embodiment of the present invention;

[0025] Figure 6 This is a partial structural diagram of the first flow-blocking part in one embodiment of the present invention (the first radial flow-blocking film is not shown).

[0026] Figure 7 for Figure 2 A schematic diagram of the structure of the central plugging device during the process of changing from a radially expanded state to a radially compressed state;

[0027] Figure 8 This is the structure of the occluder in its first deployed state according to another embodiment of the present invention (the mesh of the occluder is not shown).

[0028] Figure 9 for Figure 8 A schematic diagram of the middle plugging device in its second deployed state;

[0029] Figure 10 for Figure 8 A schematic diagram of the structure of the central plugging device during the process of changing from a radially expanded state to a radially compressed state. Detailed Implementation

[0030] To make the above-mentioned objects, features, and advantages of this utility model more apparent and understandable, the specific embodiments of this utility model will be described in detail below with reference to the accompanying drawings. Many specific details are set forth in the following description to provide a full understanding of this utility model. However, this utility model can be implemented in many other ways different from those described herein, and those skilled in the art can make similar modifications without departing from the spirit of this utility model. Therefore, this utility model is not limited to the specific embodiments disclosed below.

[0031] In the description of this utility model, it should be understood that the terms "center", "longitudinal", "transverse", "length", "width", "thickness", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "clockwise", "counterclockwise", "axial", "radial", "circumferential", etc., indicating the orientation or positional relationship are based on the orientation or positional relationship shown in the accompanying drawings, and are only for the convenience of describing this utility model and simplifying the description, and are not intended to indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation, and therefore should not be construed as a limitation of this utility model.

[0032] Furthermore, the terms "first" and "second" are used for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of indicated technical features. Thus, a feature defined as "first" or "second" may explicitly or implicitly include at least one of that feature. In the description of this utility model, "a plurality of" means at least two, such as two, three, etc., unless otherwise explicitly specified.

[0033] In this utility model, unless otherwise explicitly specified and limited, the terms "installation," "connection," "joining," and "fixing," etc., should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral part; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; they can refer to the internal communication of two components or the interaction between two components, unless otherwise explicitly limited. Those skilled in the art can understand the specific meaning of the above terms in this utility model according to the specific circumstances.

[0034] In this utility model, unless otherwise explicitly specified and limited, "above" or "below" the second feature can mean that the first feature is in direct contact with the second feature, or that the first feature is in indirect contact with the second feature through an intermediate medium. Furthermore, "above," "on top of," and "over" the second feature can mean that the first feature is directly above or diagonally above the second feature, or simply that the first feature is at a higher horizontal level than the second feature. "Below," "below," and "under" the second feature can mean that the first feature is directly below or diagonally below the second feature, or simply that the first feature is at a lower horizontal level than the second feature.

[0035] It should be noted that when an element is referred to as being "fixed to" or "set on" another element, it can be directly on the other element or there may be an intervening element. When an element is considered to be "connected to" another element, it can be directly connected to the other element or there may be an intervening element. The terms "vertical," "horizontal," "upper," "lower," "left," "right," and similar expressions used herein are for illustrative purposes only and do not represent the only possible implementation.

[0036] In this invention, "proximal end" refers to the end of the occluder that is close to the operator during the implantation procedure, and "distal end" refers to the end that is far from the operator; "axial direction" refers to the length direction of the occluder when it is being transported, and "radial direction" refers to the direction of the occluder that is perpendicular to its "axial direction".

[0037] Please see Figure 1 , Figure 2 and Figure 3This embodiment provides a plugging device 100, which can be radially compressed and loaded into a conveyor, and can also be released from the conveyor and naturally or with the aid of external force to expand to a radially expanded state. The plugging device 100 includes a plugging mesh 10 with an inner cavity and a flow-blocking structure 50 disposed in the inner cavity of the plugging mesh 10. In the structural description of this utility model, unless otherwise specified, the structure of the plugging device 100 in the radially expanded state is generally described.

[0038] The sealing net 10 includes a first sealing disc 20 and a second sealing disc 30 spaced apart axially from the sealing device 100, and a waist portion 40 located between the first sealing disc 20 and the second sealing disc 30. The first axial end of the waist portion 40 is connected to the first sealing disc 20, and the second axial end of the waist portion 40 is connected to the second sealing disc 30.

[0039] The flow-blocking structure 50 includes a first flow-blocking portion 60 and a second flow-blocking portion 70 arranged sequentially along the axial direction. The first flow-blocking portion 60 includes a first radial flow-blocking membrane 61, a first circumferential flow-blocking membrane 63, and a second radial flow-blocking membrane 62 arranged sequentially along the axial direction. The first radial flow-blocking membrane 61 is fixedly connected to the first sealing disk 20 and extends radially. The second radial flow-blocking membrane 62 is fixedly connected to the waist portion 40 and extends radially. The first circumferential flow-blocking membrane 63 extends circumferentially to form a first tubular structure 631, with openings at both axial ends. The second radial flow-blocking membrane 62 covers the opening in the first tubular structure 631 closer to the second sealing disk 30. Along the axial direction of the blocker 100, there is a gap section 41 between the first circumferential flow-blocking membrane 63 and the second flow-blocking portion 70. There is no flow-blocking membrane within the gap section 41, and the gap distance H of the gap section 41 is variable. Here, the gap distance H refers to the height of the gap section 41 in the axial direction. The term "variable interval distance H" means that the interval distance H differs depending on the state of the occluder 100. For example, the interval distance H differs when the occluder 100 is in a radially compressed state and a radially expanded state. The term "no flow-blocking membrane within the interval section 41" means that neither the inner nor outer wall of the interval section 41 is fixedly connected to or covered with a flow-blocking membrane. However, flow-blocking membranes in adjacent areas of the interval section 41 are allowed to enter the inner cavity of that interval section 41. For example, when the occluder 100 is in a radially compressed state, a portion (such as the middle region) of the second radial flow-blocking membrane 62 may enter the inner cavity of the interval section 41.

[0040] By providing a first circumferential choke membrane 63 and a second radial choke membrane 62 in the occluder 100, with the second radial choke membrane 62 positioned within the waist 40 and covering the opening of the first tubular structure 631 of the first circumferential choke membrane 63 closer to the second occlusion disc 30, blood flow passing through the waist 40 can be blocked radially and axially, thus achieving a better occlusion effect. However, if the circumferential choke membrane located in the waist 40 extends to cover the entire waist 40 area, when the occluder 100 is implanted into the defect site and the waist 40 is subjected to radial compression from the defect site, the circumferential choke membrane located in the waist 40 is not easily deformed locally with the occlusion mesh 10, but will undergo greater deformation due to compression. This causes the axial ends of the circumferential choke membrane in the waist 40 area to pull on the occlusion discs at both ends, resulting in poor occlusion disc formation and inability to fit well against the defect opening, still causing residual shunting. In this embodiment, by setting an interval section 41 between the first circumferential flow-blocking membrane 63 and the second flow-blocking part 70, and by not setting a flow-blocking membrane in the interval area, when the waist 40 is subjected to radial compression, the first circumferential flow-blocking membrane 63 can deform independently relative to the second flow-blocking part 70, and the sealing mesh 10 in the interval area can adapt well to the shape of the defect and deform, reducing the possibility that the flow-blocking membrane in the waist 40 will pull the sealing discs at both ends due to large deformation, thereby effectively reducing the occurrence of poor shaping of the sealing discs during the operation, and thus improving the sealing effect of the occluder 100.

[0041] In this embodiment, in the radially deployed state (also referred to as the fully deployed state of the occluder 100, hereinafter the same), the first occluder disc 20 and the second occluder disc 30 are generally disc-shaped, and the waist portion 40 is generally tubular. The radial dimensions of the first occluder disc 20 and the second occluder disc 30 are both larger than the radial dimension (or radial width, diameter, hereinafter the same) of the waist portion 40. After implantation into the defect site, the waist portion 40 is used to fill the defect hole, while the first occluder disc 20 and the second occluder disc 30 respectively cover the openings at both ends of the defect hole.

[0042] Exemplarily, the first sealing disc 20, the second sealing disc 30, and the waist portion 40 can be integrally woven from one or more braiding filaments 101. For example, the braiding filaments 101 are cross-woven to form a mesh-like structure, and then the two ends of the mesh-like structure are closed, and finally heat-set to form the first sealing disc 20, the second sealing disc 30, and the waist portion 40. The first sealing disc 20 and the second sealing disc 30 are both disc-shaped or frustum-shaped, while the waist portion 40 is tubular. The cross-sectional shape of the first sealing disc 20, the second sealing disc 30, and the waist portion 40 can be selected from one or more of the following: circular, elliptical, polygonal, and petal-shaped. In other embodiments,

[0043] The first occlusion disc 20 includes an integrally formed first distal disc 21, a first proximal disc 22, and a first ridge 23 connecting the first proximal disc 22 and the first distal disc 21. The first distal disc 21 and the first proximal disc 22 both extend in a generally radial direction to form a disc shape. The outer edge of the first distal disc 21 is connected to the distal end of the first ridge 23, and the proximal end of the first ridge 23 is connected to the outer edge of the first proximal disc 22. The second occlusion disc 30 includes an integrally formed second proximal disc 31 and a second distal disc 32, and a second ridge 33 connecting the second proximal disc 31 and the second distal disc 32. The second distal disc 32 and the second proximal disc 31 both extend in a generally radial direction to form a disc shape. The outer edge of the second distal disc 32 is connected to the distal end of the second ridge 33, and the proximal end of the second ridge 33 is connected to the outer edge of the second proximal disc 31. It should be noted that in this embodiment, the overall shape and radial dimensions of the first sealing disc 20 and the second sealing disc 30 differ. In other embodiments, the shape and radial dimensions of the first sealing disc 20 and the second sealing disc 30 may be the same. The weaving method and weaving material of the waist portion 40 are basically the same as those of the first sealing disc 20 and the second sealing disc 30. It is understood that in other embodiments, the weaving method and weaving material of the waist portion 40 may also differ from those of the first sealing disc 20 and the second sealing disc 30, and may be designed according to actual needs.

[0044] The first radial flow-blocking membrane 61 extends radially and is fixedly connected within the first sealing disc 20, and the second radial flow-blocking membrane 62 extends radially and is fixedly connected within the waist section 40.

[0045] The first radial flow-blocking membrane 61 and the second radial flow-blocking membrane 62 described above can be circular sheet structures. The first radial flow-blocking membrane 61 is fixedly connected between the first proximal disc 22 and the first distal disc 21 (that is, fixedly connected within the first occlusion disc 20). The size and shape of the first radial flow-blocking membrane 61 are adapted to the size and shape of the first occlusion disc 20, such that when the first radial flow-blocking membrane 61 is disposed in the first occlusion disc 20, the outer periphery of the first radial flow-blocking membrane 61 is connected to the inner surface of the first ridge 23. The second radial flow-blocking membrane 62 is fixedly connected in the waist 40, and the size and shape of the second radial flow-blocking membrane 62 are adapted to the size and shape of the waist 40, with the edge of the second radial flow-blocking membrane 62 connected to the inner wall of the waist 40. In other embodiments, the shapes of the first radial flow-blocking membrane 61 and the second radial flow-blocking membrane 62 can also be elliptical or any other suitable shape, and their specific shapes can be determined according to the shape of the cardiac defect to be blocked, as long as they can achieve an effective blocking effect. In other embodiments, the first radial flow barrier membrane 61 may also be attached to the outer surface of the first sealing disc 20.

[0046] Optionally, refer to Figure 3 , Figure 4In this embodiment, the first radial flow-blocking membrane 61 can also be fixedly connected to the first distal disk 21 via a first fixing part 611. The first fixing part 611 surrounds the central axis of the occluder 100 and is located between the central axis of the occluder 100 and the edge of the first occluder disk 20. By providing the first fixing part 611, the first radial flow-blocking membrane 61 can better follow the first distal disk 21 to move distally during the radial compression process of the occluder 100 (see reference). Figure 7 This helps the first flow-blocking portion 60 to be better compressed radially, and on the other hand, it allows the first radial flow-blocking membrane 61 to better adhere to the first distal disk 21, which not only achieves a better sealing effect but also helps to increase the endothelialization speed of the first distal disk 21. The ratio between the minimum radial distance from the first fixing portion 611 to the edge of the first sealing disk 20 and the radial dimension of the first sealing disk 20 ranges from 1 / 8 to 3 / 8. For example, this ratio can be 1 / 8, 1 / 6, 1 / 4, 1 / 3, or 3 / 8. By reasonably setting this ratio range, the first fixing portion 611 can better drive the first radial flow-blocking membrane 61 to adhere to the first distal disk 21. In other embodiments, the first fixing portion 611 may be omitted.

[0047] Furthermore, the first radial flow-blocking membrane 61 can also be fixedly connected to the inner edge wall of the first sealing disk 20 (i.e., the inner wall of the first ridge 23) via the first edge fixing part 612. The first edge fixing part 612 enables the edge of the first radial flow-blocking membrane 61 to better fit with the inner edge wall of the first sealing disk 20, which is beneficial to improving the sealing effect.

[0048] A first circumferential flow-blocking membrane 63 is circumferentially disposed in the waist region 40. The first circumferential flow-blocking membrane 63 extends circumferentially to form a first tubular structure 631, with openings at both axial ends. The first tubular structure 631 is integrally fitted with the inner wall of the waist region 40. When the occluder 100 is implanted into the cardiac defect site, the first circumferential flow-blocking membrane 63 adheres closely to the opening of the defect site, facilitating the adhesion of blood cells and thrombi and accelerating endothelial cell migration, thereby blocking blood flow and accelerating the occlusion process. The distal end of the first circumferential flow-blocking membrane 63 can block blood flowing into the gap between the disc surface and human tissue. Furthermore, because the first circumferential flow-blocking membrane 63 is disposed within the waist region 40, it prevents the first circumferential flow-blocking membrane 63 from detaching from the waist region 40 and becoming free within the human body.

[0049] The second radial choke membrane 62 covers the opening in the first tubular structure 631 closer to the second occlusion disc 30 (e.g., the proximal opening of the first tubular structure 631). In this embodiment, the edge of the second radial choke membrane 62 is fixedly connected to the edge of the proximal opening of the first tubular structure 631, and the edge of the second radial choke membrane 62 is fixedly connected to the waist 40 via a third fixing part (not shown), so that the second radial choke membrane 62 completely covers the proximal opening of the first tubular structure 631. Because the second radial choke membrane 62 covers the proximal opening of the first tubular structure 631, it can better block the radial and axial blood flow in the waist 40, thereby achieving a better occlusion effect. Furthermore, the proximal opening of the first tubular structure 631 is connected to the edge of the second radial flow-blocking membrane 62, and the edge of the second radial flow-blocking membrane 62 is connected to the waist 40. This allows the first tubular structure 631 and the second radial flow-blocking membrane 62 to form a bag-like structure and fully conform to the inner wall of the waist 40 when the occluder 100 is radially expanded, further improving the sealing effect. Moreover, when the occluder 100 is radially compressed, the first tubular structure 631 and the second radial flow-blocking membrane 62 can better follow the deformation of the waist 40 (see reference). Figure 7 This effectively reduces the size of the sheath. In other embodiments, the third fixing part can be omitted.

[0050] Along the axial direction of the occluder 100, the second radial flow-blocking membrane 62 and the second flow-blocking portion 70 are spaced apart, such that there is a gap section 41 between the second radial flow-blocking membrane 62 and the second flow-blocking portion 70, and there is no flow-blocking membrane in the gap section 41. By setting the gap section 41 between the second radial flow-blocking membrane 62 and the second flow-blocking portion 70, and not setting the flow-blocking membrane in the gap area, when the waist 40 is subjected to radial compression, the occlusion mesh 10 in the gap area can adapt well to the shape deformation of the defect, so that the first circumferential flow-blocking membrane 63 does not need to undergo large deformation, thereby effectively reducing the possibility of poor formation of the occlusion disc during the operation, and thus improving the occlusion effect of the occluder 100.

[0051] Optionally, in this embodiment, the second flow-blocking portion 70 may include a third radial flow-blocking membrane 71, which extends radially and is fixedly connected within the second sealing disc 30. The third radial flow-blocking membrane 71 is fixedly connected between the second proximal disc 31 and the second distal disc 32 (i.e., fixedly connected within the second sealing disc 30). The size and shape of the third radial flow-blocking membrane 71 are adapted to the size and shape of the second sealing disc 30. For example, the third radial flow-blocking membrane 71 may be a circular sheet structure, such that when the third radial flow-blocking membrane 71 is disposed in the second sealing disc 30, the outer periphery of the third radial flow-blocking membrane 71 is connected to the inner surface of the first ridge 23. By providing the third radial flow-blocking membrane 71, the sealing effect of the sealing device 100 can be further enhanced. In other embodiments, the third radial flow-blocking membrane 71 may be omitted.

[0052] Optionally, refer to Figure 3 , Figure 5 In this embodiment, the third radial flow-blocking membrane 71 can also be fixedly connected to the second proximal disk 31 via the second fixing part 711. The second fixing part 711 surrounds the central axis of the occluder 100 and is located between the central axis of the occluder 100 and the edge of the second occluder disk 30. By providing the second fixing part 711, the third radial flow-blocking membrane 71 can better follow the second proximal disk 31 as it moves proximally during the radial compression of the occluder 100 (see reference). Figure 7 This helps the second flow-blocking portion 70 to be better radially compressed, and on the other hand, it allows the third radial flow-blocking membrane 71 to better adhere to the second proximal disk 31, which not only achieves a better sealing effect but also helps to increase the endothelialization speed of the second proximal disk 31. The ratio between the minimum radial distance from the second fixing portion 711 to the edge of the second sealing disk 30 and the radial dimension of the second sealing disk 30 ranges from 1 / 8 to 3 / 8. For example, this ratio can be 1 / 8, 1 / 6, 1 / 4, 1 / 3, or 3 / 8. By reasonably setting this ratio range, the second fixing portion 711 can better drive the third radial flow-blocking membrane 71 to adhere to the second proximal disk 31. In other embodiments, the second fixing portion 711 may be omitted.

[0053] Furthermore, the third radial flow-blocking membrane 71 can also be fixedly connected to the inner edge wall of the second sealing disk 30 (i.e., the inner wall of the second ridge 33) via the second edge fixing part 712. The second edge fixing part 712 enables the edge of the third radial flow-blocking membrane 71 to better fit with the inner edge wall of the second sealing disk 30, which is beneficial to improving the sealing effect.

[0054] Optionally, the second flow-blocking section 70 further includes a second circumferential flow-blocking membrane 72, which is partially or entirely fixed within the waist section 40. The second circumferential flow-blocking membrane 72 extends circumferentially to form a second tubular structure 721. Both axial ends of the second tubular structure 721 have openings, and the opening closer to the first occlusion disc 20 (e.g., the distal opening of the second tubular structure 721) is an open structure. The second tubular structure 721 is integrally fitted with the inner wall of the waist section 40. When the occluder 100 is implanted into the cardiac defect site, the second circumferential flow-blocking membrane 72 is close to the opening of the defect site, facilitating the adhesion of blood cells and thrombi and accelerating endothelial cell migration, thereby blocking blood flow and accelerating the occlusion process. The distal end of the second circumferential flow-blocking membrane 72 can further block blood flowing into the gap between the disc surface and human tissue. Furthermore, because the distal opening of the second tubular structure 721 is an open structure, the second radial flow-blocking membrane 62 has more room to move. This avoids the problem of the second radial flow-blocking membrane 62 interfering with the second flow-blocking part 70 due to large deformation when the waist part 40 is subjected to large radial compression from the defect area, thus preventing the deformation force from being transmitted to the first sealing plate 20 and the second sealing plate 30 and causing poor plate surface formation. Also, when the sealing device 100 is radially compressed, the second radial flow-blocking membrane 62 is less likely to interfere with the second flow-blocking part 70 and accumulate (see reference). Figure 7 This causes difficulties in retracting the sheath. Furthermore, the second circumferential flow-restricting membrane 72 is disposed within the waist portion 40, thus preventing the first circumferential flow-restricting membrane 63 from detaching from the waist portion 40 and becoming free within the body. In other embodiments, the second circumferential flow-restricting membrane 72 may be omitted.

[0055] Optionally, in this embodiment, the opening edge of the second tubular structure 721 closer to the first sealing disc 20 (or the axial end of the second tubular structure 721 closer to the first sealing disc 20) can be fixedly connected to the inner wall of the waist portion 40 via a fourth fixing part (not shown). This allows the second tubular structure 721 to fully expand and fit snugly against the inner wall of the waist portion 40 when the sealing device 100 is in a radially expanded state, further improving the sealing effect. Furthermore, when the sealing device 100 is radially compressed, the second tubular structure 721 can better follow the deformation of the waist portion 40, effectively reducing the sheath size. In other embodiments, the fourth fixing part may be omitted.

[0056] In other embodiments, the first tubular structure 631 and / or the second tubular structure 721 may be wrapped around the outer wall of the waist 40.

[0057] In this embodiment, the first fixing part 611, the second fixing part 711, the third fixing part, the fourth fixing part, the first edge fixing part 612, and the second edge fixing part 712 can be a ring structure formed by stitches. The stitches can be continuous or discrete. In other embodiments, the fixing part can be a ring structure formed by adhesive units. The adhesive units can be continuous or discrete, or they can be composed of any other suitable fixing units 643.

[0058] Optionally, in this embodiment, the first flow-blocking part 60 further includes a first annular flow-blocking membrane 64, which is located within the first occlusion disc 20 and extends radially along the occluder 100. The first annular flow-blocking membrane 64 includes a first inner ring edge and a first outer ring edge. The first inner ring edge is fixedly connected to the axial end of the first tubular structure 631 closer to the first radial flow-blocking membrane 61, and the first outer ring edge is fixedly connected to the first radial flow-blocking membrane 61. The aforementioned first annular flow-blocking membrane 64 can block blood flow in the gap between the first proximal disc 22 and the tissue wall, thereby further improving the sealing effect of the occluder 100.

[0059] The position where the first outer ring edge is fixedly connected to the first radial flow-blocking membrane 61 is optional. For example, the first outer ring edge can be fixedly connected to the outer edge of the first radial flow-blocking membrane 61. This configuration allows the first annular flow-blocking membrane 64 to better fit and conform to the inner wall of the first sealing disc 20, increasing the flow-blocking range. Furthermore, when the sealing device 100 is radially compressed, it can move away from the first radial flow-blocking membrane 61 to achieve radial compression. Also, there is no overlap of the flow-blocking membranes at the connection point between the first annular flow-blocking membrane 64 and the first radial flow-blocking membrane 61, thereby reducing the sheath size.

[0060] In other embodiments, the axial end of the first tubular structure 631 closer to the first radial choke membrane 61 can be directly fixedly connected to the first radial choke membrane 61. Since the first annular choke membrane 64 is omitted, the amount of membrane used can be reduced, and for the biodegradable occluder 100, a smaller amount of membrane can reduce tissue irritation during degradation.

[0061] Optionally, in this embodiment, the second flow-blocking portion 70 further includes a second annular flow-blocking membrane 73. The second annular flow-blocking membrane 73 is located within the second occlusion disc 30 and extends radially along the occluder 100. The second annular flow-blocking membrane 73 includes a second inner ring edge and a second outer ring edge. The second inner ring edge is fixedly connected to the axial end of the second tubular structure 721 closer to the third radial flow-blocking membrane 71, and the second outer ring edge is fixedly connected to the third radial flow-blocking membrane 71. The aforementioned second annular flow-blocking membrane 73 can block blood flow in the gap between the second distal disc 32 and the tissue wall, thereby further improving the sealing effect of the occluder 100. The position where the second outer ring edge is fixedly connected to the third radial flow-blocking membrane 71 is optional. For example, the second outer ring edge can be fixedly connected to the outer edge of the third radial flow-blocking membrane 71. This configuration allows the second annular flow-blocking membrane 73 to better fit and adhere to the inner wall of the second sealing disc 30, increasing the flow-blocking range. When the sealing device 100 is radially compressed, it can move away from the third radial flow-blocking membrane 71 to achieve radial compression. Furthermore, there is no overlap of flow-blocking membranes at the connection between the second annular flow-blocking membrane 73 and the third radial flow-blocking membrane 71, thereby reducing the sheath size.

[0062] In other embodiments, the axial end of the second tubular structure 721 closer to the second radial choke membrane 62 is directly fixedly connected to the second radial choke membrane 62. Because the second annular choke membrane 73 is omitted, the amount of membrane used can be reduced, and for the biodegradable occluder 100, less membrane usage can reduce tissue irritation during degradation.

[0063] Reference Figure 3 , Figure 6 In this embodiment, the first annular flow barrier membrane 64 includes a first annular unit 641 and a second annular unit 642. Both the first annular unit 641 and the second annular unit 642 are annular and extend radially along the plug 100. The inner edge of the first annular unit 641 is fixedly connected to the axial end of the first tubular structure 631 that is closer to the first radial flow barrier membrane 61. The outer edge of the first annular unit 641 is fixedly connected to the inner edge of the second annular unit 642 through a fixing unit 643. The outer edge of the second annular unit 642 (i.e., the first outer ring edge of the first annular flow barrier membrane 64) is fixedly connected to the outer edge of the first radial flow barrier membrane 61. The fixing unit 643 can be a suture or an adhesive, etc.

[0064] Optionally, in this embodiment, the second annular unit 642 and the first radial flow-blocking membrane 61 can be an integral structure. This arrangement eliminates the annular gap between the outer edge of the first radial flow-blocking membrane 61 and the first outer ring edge of the first annular flow-blocking membrane 64, thereby further improving the sealing effect of the edge of the first sealing disc 20. The connection between the outer edge of the first annular unit 641 and the inner edge of the second annular unit 642 is located between the edge of the first sealing disc 20 and the central axis. After the occluder 100 is implanted, this connection is tightly pressed between the first distal disc 21 and the tissue wall by the first sealing disc 20, thus preventing blood leakage at this connection. In other embodiments, the second annular unit 642 and the first radial flow-blocking membrane 61 can be separate structures, manufactured separately and then spliced ​​together.

[0065] Optionally, in this embodiment, the first annular unit 641, the second radial flow-blocking membrane 62, and the first circumferential flow-blocking membrane 63 are integral structures, and / or, the second annular flow-blocking membrane 73 and the second circumferential flow-blocking membrane 72 are integral structures. This configuration further reduces the possibility of residual flow diversion in the plugger 100, which is beneficial for improving the plugging effect. Furthermore, due to the integral structure, the risk of flow-blocking membrane detachment can be effectively avoided. In other embodiments, the first annular unit 641, the second radial flow-blocking membrane 62, and the first circumferential flow-blocking membrane 63 can be separate structures, manufactured separately and then spliced ​​together. Additionally, the second annular flow-blocking membrane 73 and the second circumferential flow-blocking membrane 72 can also be separate structures, manufactured separately and then spliced ​​together.

[0066] In this embodiment, refer to Figure 8 , Figure 10 The plugging device 100 also includes a cap 81 and a plug 82. The cap 81 is disposed on the first plugging disc 20, and the braided wires 101 in the first plugging disc 20 converge at the distal end and are fixed in the cap 81. The plug 82 is disposed on the second plugging disc 30, and the braided wires 101 in the second plugging disc 30 converge at the proximal end and are fixed in the distal end of the plug 82. The proximal end of the plug 82 is a connecting end for connecting to a conveying device (such as a conveying cable in the conveying device, not shown in the figure).

[0067] The occluder 100 may further include a locking element 90, which passes through the inner cavity of the occlusion mesh 10. The distal end of the locking element 90 is fixedly connected to the end cap 81, and the proximal end of the locking element 90 is detachably connected to the plug head 82 via an interference fit. After the occluder 100 is released, the distal end of the occluder 100 can be gradually pulled towards the proximal end through the locking element 90, restoring the occluder 100 to its double-disc structure. Then, the distance between the distal and proximal ends of the occluder 100 is fixed by the interference fit between the locking element 90 and the plug head 82. Thus, the occluder 100 restores and maintains a stable double-disc structure after release. It is understood that the shape, structure, and connection method of the locking element 90 with the end cap 81 and the plug head 82 are not limited to the methods provided in this embodiment, and structures and connection methods commonly used in the art can also be adopted. It is understood that in other embodiments, the locking member 90 may be omitted, as long as the structure of the medical device is stable in its naturally unfolded state, such as the occluder 100 formed by nickel-titanium wire braiding. The locking member 90 enables the proximal end of the locking member 90 to lock and the proximal end of the occlusion mesh 10 to separate (i.e., unlock).

[0068] In this embodiment, when the occluder 100 is in the radially deployed state, the spacing H of the interval segments 41 is 0~3mm, for example, 0, 0.5mm, 1mm, 1.5mm, 2mm, 2.5mm, 3mm, etc. In other embodiments, the spacing H can be greater than 3mm. Compared to the case where the spacing H of the interval segments 41 is greater than 3mm, the range of the spacing H in this embodiment allows the waist region 40 to have a better occlusion effect and can achieve faster endothelialization.

[0069] Understandably, for a occluder 100 that requires locking member 90 to help maintain a radially deployed state, its radially deployed state includes a first deployed state in which the occluder 100 is radially deployed and locking member 90 is mutually locked to the occlusion mesh 10, and a second deployed state in which the occluder is radially deployed and locking member 90 is mutually unlocked to the occlusion mesh 10. Exemplarily, in this embodiment, the occluder 100 requires locking member 90 to help maintain a radially deployed state, referring to... Figure 8 When in the first deployed state, the spacing H of the interval section 41 is 0, and the proximal end of the first circumferential flow-blocking membrane 63 and the distal end of the second flow-blocking section 70 are in contact with each other. (Refer to...) Figure 9 When in the second unfolded state, the interval distance H of the interval section 41 is greater than 0, approximately 2 mm. This configuration allows the first circumferential flow-blocking membrane 63 and the second flow-blocking section 70 to remain relatively independent after the occluder 100 is implanted, while maximizing the occlusion effect and endothelialization rate in the waist region 40. During radial compression, the first circumferential flow-blocking membrane 63 and the second flow-blocking section 70 can separate from each other (see reference). Figure 7This avoids difficulties in sheath insertion caused by the accumulation of the flow-blocking membrane. For the plug 100, which can maintain the radially deployed state without the need for the locking element 90, its radially deployed state is its fully deployed radial state (or natural deployment state) that is not subject to external radial constraints.

[0070] Reference Figure 10 When the radial expansion state transitions to the radial compression state, the spacing distance H of the interval segment 41 further increases.

[0071] Reference Figure 8 Each of the first radial flow-blocking membrane 61, the second radial flow-blocking membrane 62, and the third radial flow-blocking membrane 71 has a through hole (not shown in the figure) in its middle. The diameter of the through hole is adapted to the size of the locking member 90 so that the proximal end of the locking member 90 can pass through the through hole and be detachably connected to the bolt head 82. In this embodiment, the through hole is a circular hole with a diameter of 0.5 to 1 mm to ensure that the locking member 90 can pass through while avoiding an excessively large opening that would affect the sealing effect. It is understood that in other embodiments, the through hole is not limited to a circular hole and can be a through hole of other shapes, such as a square hole, a strip hole, a cross slit, etc.

[0072] Reference Figure 1 In this embodiment, the occluder 100 is an absorbable occluder 100. The occlusion mesh 10 and the flow-blocking structure 50 are both made of biodegradable polymer materials. The biodegradable polymer materials are selected from at least one of polylactic acid (PLA), racemic PLA, polyglycolic acid, polylactic-co-hydroxyacetic acid copolymer, polyhydroxyalkanoates, polydioxanone, polycaprolactone, polygluconic acid, polyhydroxybutyric acid, polyanhydride, polyphosphate ester, polyglycolic acid, and polydioxanone. Because the occluder 100 is made of biodegradable polymer materials, it can degrade and be absorbed by the body after endothelialization, allowing the defect to be completely repaired by the body's own tissue, thereby eliminating the long-term complications caused by the permanent presence of the metal alloy occluder 100 in the body.

[0073] In other embodiments, the braided filaments 101 may also be made of metal materials with shape memory properties, such as nickel-titanium alloys, and the flow-blocking structure 50 may be made of polymer materials with good biocompatibility, such as PET and PTFE. The materials used for the blocking mesh 10 and the flow-blocking structure 50 can be selected as needed.

[0074] The technical features of the above embodiments can be combined in any way. For the sake of brevity, not all possible combinations of the technical features in the above embodiments are described. However, as long as there is no contradiction in the combination of these technical features, they should be considered to be within the scope of this specification.

[0075] The above-described embodiments are merely illustrative of several implementations of this utility model, and while the descriptions are specific and detailed, they should not be construed as limiting the scope of this utility model. It should be noted that those skilled in the art can make various modifications and improvements without departing from the concept of this utility model, and these all fall within the protection scope of this utility model. Therefore, the protection scope of this utility model should be determined by the appended claims.

Claims

1. A sealing device, characterized in that, include: An occlusion mesh with an inner cavity includes a first occlusion disc and a second occlusion disc spaced apart axially in the occlusion device, and a waist portion located between the first occlusion disc and the second occlusion disc. The first axial end of the waist portion is connected to the first occlusion disc, and the second axial end of the waist portion is connected to the second occlusion disc. A flow-blocking structure is disposed within the inner cavity of the plugging mesh. The flow-blocking structure includes a first flow-blocking portion and a second flow-blocking portion arranged sequentially along the axial direction. The first flow-blocking portion includes a first radial flow-blocking membrane, a first circumferential flow-blocking membrane, and a second radial flow-blocking membrane arranged sequentially along the axial direction. The first radial flow-blocking membrane is fixedly connected to the first plugging disc and extends radially when the plugging device is in a radially deployed state. The second radial flow-blocking membrane is fixedly connected to the waist portion and extends radially when the plugging device is in a radially deployed state. The first circumferential flow-blocking membrane extends circumferentially to form a first tubular structure. Both ends of the first tubular structure have openings. The second radial flow-blocking membrane covers the opening of the first tubular structure that is closer to the second plugging disc. Along the axial direction of the plugging device, there is a gap between the first circumferential flow-blocking membrane and the second flow-blocking portion. There is no flow-blocking membrane in the gap, and the interval distance of the gap is variable.

2. The occluder according to claim 1, characterized in that, The second flow-blocking part includes a third radial flow-blocking membrane, which is fixedly connected to the second sealing disc and extends radially when the sealing device is in a radially deployed state.

3. The occluder of claim 2, wherein, The second flow-blocking part also includes a second circumferential flow-blocking membrane, which is partially or completely fixed inside the waist. The second circumferential flow-blocking membrane extends circumferentially to form a second tubular structure. Both ends of the second tubular structure have openings, and the opening closer to the first sealing plate in the second tubular structure is an open structure.

4. The occluder of claim 1, wherein, In the first tubular structure, the axial end closer to the first radial flow-blocking membrane is directly fixedly connected to the first radial flow-blocking membrane; or, the first flow-blocking part further includes a first annular flow-blocking membrane, which is located within the first sealing disc and extends radially along the sealing device when the sealing device is in a radially deployed state. The first annular flow-blocking membrane includes a first inner ring edge and a first outer ring edge. The first inner ring edge is fixedly connected to the axial end closer to the first radial flow-blocking membrane in the first tubular structure, and the first outer ring edge is fixedly connected to the first radial flow-blocking membrane.

5. The occluder of claim 3, wherein, The axial end of the second tubular structure closer to the second radial flow-blocking membrane is directly fixedly connected to the second radial flow-blocking membrane; or, the second flow-blocking part further includes a second annular flow-blocking membrane, which is located inside the second sealing disc and extends radially along the sealing device when the sealing device is in a radially deployed state. The second annular flow-blocking membrane includes a second inner ring edge and a second outer ring edge. The second inner ring edge is fixedly connected to the axial end of the second tubular structure closer to the third radial flow-blocking membrane, and the second outer ring edge is fixedly connected to the third radial flow-blocking membrane.

6. The occluder of claim 1, wherein, The first flow-blocking section further includes a first annular flow-blocking membrane, which is located within the first sealing disc. The first annular flow-blocking membrane includes a first annular unit and a second annular unit, both of which are annular and extend radially along the sealing device. The inner edge of the first annular unit is fixedly connected to the axial end of the first tubular structure closer to the first radial flow-blocking membrane. The outer edge of the first annular unit is fixedly connected to the inner edge of the second annular unit, and the outer edge of the second annular unit is fixedly connected to the outer edge of the first radial flow-blocking membrane. The second annular unit is also fixedly connected to the first radial flow-blocking membrane. The flow-blocking membrane is an integral structure; and / or, the second flow-blocking portion includes a third radial flow-blocking membrane, a second annular flow-blocking membrane, and a second circumferential flow-blocking membrane, the second circumferential flow-blocking membrane being partially or entirely fixed within the waist portion, the second circumferential flow-blocking membrane extending circumferentially to form a second tubular structure, the third radial flow-blocking membrane and the second annular flow-blocking membrane being located within the second sealing disc, the second annular flow-blocking membrane including a second inner ring edge and a second outer ring edge, the second inner ring edge being fixedly connected to the axial end of the second tubular structure closer to the third radial flow-blocking membrane, and the second outer ring edge being fixedly connected to the outer edge of the third radial flow-blocking membrane.

7. The occluder of claim 1, wherein, The first occlusion disc includes a first distal disc and a first proximal disc. The first radial flow-blocking membrane is fixedly connected to the first distal disc via a first fixing part. The first fixing part surrounds the central axis of the occluder and is located between the central axis of the occluder and the edge of the first occlusion disc. And / or, the second occlusion disc includes a second distal disc and a second proximal disc. The second flow-blocking part includes a third radial flow-blocking membrane. The third radial flow-blocking membrane is fixedly connected to the second proximal disc via a second fixing part. The second fixing part surrounds the central axis of the occluder and is located between the central axis of the occluder and the edge of the second occlusion disc.

8. The occluder of claim 1, wherein, The first sealing disc includes a first distal disc and a first proximal disc. The first radial flow-blocking membrane is fixedly connected to the first distal disc via a first fixing part. The first fixing part is an annular structure formed by sutures. The ratio between the minimum radial distance from the first fixing part to the edge of the first sealing disc and the radial dimension of the first sealing disc is in the range of 1 / 8 to 3 / 8. And / or, the second sealing disc includes a second distal disc and a second proximal disc. The second flow-blocking part includes a third radial flow-blocking membrane. The third radial flow-blocking membrane is fixedly connected to the second proximal disc via a second fixing part. The second fixing part is an annular structure formed by sutures. The ratio between the minimum radial distance from the second fixing part to the edge of the second sealing disc and the radial dimension of the second sealing disc is in the range of 1 / 8 to 3 / 8.

9. The occluder of claim 1, wherein, The first flow-blocking section further includes a first annular flow-blocking membrane, which is located within the first sealing disc. The first annular flow-blocking membrane includes a first annular unit and a second annular unit, both of which are annular and extend radially along the sealing device. The inner edge of the first annular unit is fixedly connected to the axial end of the first tubular structure closer to the first radial flow-blocking membrane. The outer edge of the first annular unit is fixedly connected to the inner edge of the second annular unit, and the outer edge of the second annular unit is fixedly connected to the first radial flow-blocking membrane. The first annular unit, the second radial flow-blocking membrane, and the first circumferential flow-blocking membrane are integrally formed. The structure is as follows: and / or, the second flow-blocking part includes a third radial flow-blocking membrane, a second annular flow-blocking membrane, and a second circumferential flow-blocking membrane. The second circumferential flow-blocking membrane is partially or completely fixed within the waist portion. The second circumferential flow-blocking membrane extends circumferentially to form a second tubular structure. The third radial flow-blocking membrane and the second annular flow-blocking membrane are located within the second sealing disk. The second annular flow-blocking membrane includes a second inner ring edge and a second outer ring edge. The second inner ring edge is fixedly connected to the axial end of the second tubular structure closer to the third radial flow-blocking membrane. The second outer ring edge is fixedly connected to the third radial flow-blocking membrane. The second annular flow-blocking membrane and the second circumferential flow-blocking membrane are an integral structure.

10. The occluder of claim 1, wherein, The outer edge of the second radial flow-blocking membrane is stitched and fixedly connected to the waist portion; and / or, the second flow-blocking portion includes a second circumferential flow-blocking membrane, the second circumferential flow-blocking membrane is partially or completely fixed within the waist portion, the second circumferential flow-blocking membrane extends circumferentially to form a second tubular structure, and the axial end of the second tubular structure closer to the first sealing disc is stitched and fixedly connected to the waist portion.

11. The occluder of claim 1, wherein, The occluder is an absorbable occluder, which also includes an end cap, a plug, and a locking element. The occluder mesh is woven from braided wires to form a mesh structure. The end cap is used to gather one axial end of the occluder mesh, and the plug is used to gather the other axial end of the occluder mesh. The locking element is inserted into the inner cavity of the occluder mesh, and one axial end of the locking element is fixedly connected to the end cap, while the other axial end of the locking element is detachably connected to the plug.

12. The plugging device according to any one of claims 1-11, characterized in that, When the plug is in the radially deployed state, the maximum axial spacing distance of the interval section is 0~3mm.

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