Electromagnetic shielding deep brain stimulation and acquisition device

Abstract

The utility model discloses a kind of electromagnetic shielding's mouse brain deep electrical stimulation and collection device, including protective shell and shielding shell, protective shell bottom is equipped with opening, top is equipped with connecting port, opening is fixedly adhered with animal skull surface, electrode main body, adapter terminal wire and USB conversion interface connected in sequence are equipped in protective shell, electrode main body implants in animal brain through opening;Shielding shell is inserted with connecting port, shielding shell is inserted with connecting port in, USB interface and preamplifier are equipped in shielding shell, USB interface connects USB conversion interface, preamplifier is connected host computer by data line and passes out shielding shell.The utility model, the production and composition of electrode are modularized split, standardization production and surgical implantation process;Modularization installed USB conversion interface hardware cost is very small, improve the Omnetics interface utilization of host computer;USB conversion interface and electrode main body between using adapter terminal wire, namely soft line connection, can avoid the screw drop caused by multiple plug and unplug, prolongs the implantation time of electrode.

Description

Technical Field

[0001] This utility model relates to the field of neuroscience technology, specifically to an electromagnetically shielded deep brain electrical stimulation and acquisition device for rats. Background Technology

[0002] In biomedical research and clinical practice, electroencephalogram (EEG) and electromyography (EMG) signals, as important physiological indicators reflecting the activity of the nervous system and muscles, play an irreplaceable role in understanding brain function. EEG / EMG acquisition systems are highly integrated physiological signal acquisition devices. They use specific electrodes and sensors, attached or inserted into the scalp (for EEG) and the surface or interior of muscles (for EMG), respectively, to acquire EEG and EMG signals in a non-invasive or invasive manner. These signals are then amplified, filtered, and converted into digital signals for further analysis and processing by a computer. To understand the neural electrical activity in deep and localized brain regions, multi-channel in vivo electrophysiological techniques can be used to record local field potentials (LFPs) in brain regions during experiments. LFPs reflect the synchronous activity of neuronal populations; their amplitude is very weak, typically less than 400 μV. Therefore, high-sensitivity preamplifiers are required for signal acquisition, followed by filtering and analog-to-digital conversion to obtain high-quality neural signals.

[0003] Chronic implantation electrodes are a common method that allows recording while allowing rats free movement. Chronic implantation electrodes are secured to the skull using screw electrodes, or microwire electrode arrays are inserted into the target brain region. Dental cement can be used to fix the head, allowing for free movement during recording.

[0004] However, the expensive equipment interfaces and complex electrode implantation procedures, along with the high technical requirements for experimental operation, result in high overall hardware and surgical time costs. Furthermore, signal acquisition is susceptible to interference from environmental noise, motion artifacts, and unstable equipment interfaces, further increasing the experimental difficulty.

[0005] It is evident that existing invasive electrodes suitable for animal experiments suffer from problems such as complex use and high experimental costs. Utility Model Content

[0006] The technical problem to be solved by this invention is that current invasive electrodes for animal experiments are complex to use and have high experimental costs.

[0007] To solve the above-mentioned technical problems, the technical solution adopted by this utility model is to provide an electromagnetically shielded deep brain electrical stimulation and acquisition device for rats, comprising:

[0008] A protective shell has an opening at the bottom and a connection port at the top. The opening is adhered and fixed to the surface of the animal's skull. Inside the protective shell are an electrode body, an adapter terminal cable, and a USB conversion interface, connected in sequence. The electrode body is implanted into the animal's brain through the opening.

[0009] A shielding shell is inserted into the connection port. The shielding shell contains a USB interface and a preamplifier. The USB interface is connected to the USB conversion interface. The preamplifier is connected to the host computer via a data cable that passes through the shielding shell.

[0010] In a preferred embodiment, the opening is elliptical and protrudes, and the inner wall of the opening has a plurality of grooves.

[0011] In another preferred embodiment, the protective shell is integrally formed with a shield-shaped portion and a square portion, the shield-shaped portion and the square portion together forming an accommodating space.

[0012] Furthermore, in the above embodiment, the square portion is provided with positioning holes to fix the USB conversion interface.

[0013] Alternatively, in the above embodiments, one end of the shielding shell is provided with an insertion interface, the insertion interface including a shield-shaped plate and a square plate that are independent of each other, the shield-shaped plate conforming to the inner wall shape of the shield-shaped part, and the square plate conforming to the outer wall shape of the square part.

[0014] Furthermore, in the above embodiments, the shield-shaped portion and the shield-shaped plate are provided with magnetic suction holes for the rubidium magnet to pass through, and the shield-shaped plate and the protective shell are magnetically fixed together.

[0015] In another preferred embodiment, a protective cover is further included, which is inserted into the connection port and closes the connection port, and the protective shell is connected to the shielding shell or the protective cover.

[0016] Furthermore, in the above embodiments, the protective cover is provided with a cover plate and an arc-shaped plate, the arc-shaped plate is vertically disposed on the inner side of the cover plate, the arc-shaped plate fits the inner wall shape of the shield-shaped part, and the cover plate covers the connection port.

[0017] In another preferred embodiment, the shielding shell includes a shielding housing and a shielding shell cover, the shielding housing being configured as a square tubular shape, and the shielding shell cover having a positioning portion for positioning the data cable.

[0018] In another preferred embodiment, both the protective shell and the shielding shell are wrapped with an electromagnetic shielding layer.

[0019] As can be seen from the above technical solution, the advantages and positive effects of the electromagnetically shielded deep brain electrical stimulation and acquisition device for rats in this application are as follows: Modularizing the electrode fabrication and construction allows for the concentration of electrode conversion interface device continuity testing during the electrode fabrication stage. This enables streamlined electrode production and fabrication in small laboratories, standardizing the fabrication and surgical implantation process, thereby saving experimental preparation time and reducing animal suffering and safety risks associated with prolonged anesthesia. The modular USB conversion interface is designed to adapt to the omnetics interfaces commonly used in various recording systems. Compared to omnetics interfaces, the USB conversion interface has extremely low hardware costs, and the modular combination improves the utilization rate of the host computer's omnetics interface. In small laboratory research, this significantly reduces the fabrication and usage costs of individual electrodes. The USB conversion interface is connected to the electrode body via a flexible connector cable. During actual use, there is no stress on the implanted electrode area, thus avoiding screw loosening caused by repeated insertion and removal, and extending the electrode body implantation time. Attached Figure Description

[0020] The accompanying drawings, which are incorporated in and form part of this specification, illustrate embodiments consistent with the invention and, together with the description, serve to explain the principles of the invention.

[0021] To more clearly illustrate the technical solutions in the embodiments of the present invention or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, for those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0022] Figure 1 This is an exploded view of the structure of this utility model during the experiment;

[0023] Figure 2 This is a side view of the protective shell and shielding shell of this utility model;

[0024] Figure 3 This is a schematic diagram of the assembly of the present invention in a non-experimental setting;

[0025] Figure 4 This is a side view of the protective shell and protective cover of this utility model;

[0026] Figure 5 This is a diagram showing the working state of this utility model during the experiment;

[0027] Figure 6 This is a state diagram of the utility model in a non-experimental state.

[0028] Note: The correspondence between the components and their labels in the diagram is as follows:

[0029] Protective shell 10, shield-shaped part 101, square part 102, positioning hole 1021, opening 11, groove 111, connection port 12, electrode body 13, adapter terminal wire 14, USB conversion interface 15, shield shell 20, shield shell 201, plug interface 2010, shield-shaped plate 2011, square plate 2012, shield shell cover 202, positioning part 2021, USB interface 21, preamplifier 22, data cable 23, magnetic hole 30, protective cover 40, cover plate 41, arc plate 42, host computer 50. Detailed Implementation

[0030] To make the objectives, technical solutions, and advantages of the embodiments of this application clearer, the technical solutions of the embodiments of this application will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of this application, not all embodiments. Based on the embodiments of this application, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of this application. The electromagnetically shielded deep brain electrical stimulation and acquisition device for rats provided by this utility model standardizes the manufacturing and surgical implantation process, thereby saving experimental preparation and time, reducing the manufacturing and use cost of a single electrode, and extending the electrode implantation time. The utility model will be described in detail below with reference to the accompanying drawings and specific embodiments.

[0031] To overcome the problems of complex use and high experimental costs associated with existing invasive electrodes suitable for animal experiments, see [reference needed]. Figure 1 and Figure 2 This invention provides an electromagnetically shielded deep brain electrical stimulation and acquisition device for rats, comprising a protective shell 10 and a shielding shell 20.

[0032] The protective shell 10 has an opening 11 at the bottom and a connection port 12 at the top. The opening 11 is adhered and fixed to the surface of the animal's skull. Inside the protective shell 10 are an electrode body 13, an adapter terminal cable 14, and a USB conversion interface 15 connected in sequence. The electrode body 13 is implanted into the animal's brain through the opening 11. The electrode body 13, the adapter terminal cable 14, and the USB conversion interface 15 are signal acquisition components. The space formed between the protective shell 10 and the shielding shell 20 effectively protects the signal acquisition components from external interference, ensuring the accuracy of experimental data.

[0033] See Figure 1 and Figure 5The shielding shell 20 is plugged into the connection port 12. The shielding shell 20 has a USB interface 21 and a preamplifier 22 inside. The USB interface 21 is connected to the USB conversion interface 15. The preamplifier 22 is connected to the host computer 50 through the shielding shell 20 via a data cable.

[0034] The electrode body 13, the adapter terminal line 14 and the USB conversion interface 15 serve as signal acquisition components, while the USB interface 21 and the data line 22 serve as information transmission components, ultimately transmitting the data to the host computer 50.

[0035] This invention has the following advantages: Modular design of the electrode fabrication and construction allows for the concentration of electrode conversion interface device continuity testing during the electrode fabrication stage. This enables streamlined electrode production in small laboratories, standardizing the fabrication and surgical implantation process, thus saving experimental preparation time and reducing animal suffering and safety risks associated with prolonged anesthesia. The modularly installed USB conversion interface 15 is designed to adapt to the native Omnetics interface of the Intan stimulation recording system. Compared to the Omnetics interface, the USB conversion interface 15 has significantly lower hardware costs, and its modular design improves the utilization rate of the host computer's Omnetics interface. In small laboratory research, this greatly reduces the fabrication and usage costs of individual electrodes. The USB conversion interface 15 is connected to the electrode body 13 via an adapter terminal cable 14 (a flexible cable). During actual use, there is no stress on the implanted electrode area, thus preventing screw loosening due to repeated insertion and removal, and extending the electrode implantation time. The protective shell 10 and shielding shell 20 of this application not only effectively protect the signal acquisition components from external interference but also ensure the accuracy of experimental data.

[0036] Specifically, the protective shell 10 and the shielding shell 20 are made of PLA material using 3D printing technology. By employing 3D printing technology, the manufacturing process of the protective shell 10 is more flexible and economical, and can be quickly customized according to experimental needs. In addition, this technology reduces reliance on traditional molds, shortens the production cycle, and enables researchers to obtain electrode protective shells suitable for their specific experimental animal models more quickly.

[0037] The electrode body 13 comprises a helically wound electrode wire and an electrode base. The electrode wire is a single, intertwined wire, and the electrode base is a 2×2P double-row needle with a 1.27mm spacing. Multiple electrode bodies 13 can be implanted into different brain regions of experimental animals, such as rats, for stimulating and recording multiple brain regions. The helically wound design of the electrode wire increases the flexibility and suppleness of the electrode, allowing it to better adapt to the minute movements of brain tissue, thereby reducing damage to neural tissue.

[0038] The adapter terminal cable 14 includes electrical terminals, connecting wires, and adapter terminals. The electrical terminals are 2×2P dual-row pin headers, the adapter terminals are MX 1.25mm JST1.25-5P single-ended terminal cable housings, and the adapter wires are AWG 28 multi-core copper wires. The conversion interface is a connector that combines a convex Micro-USB female port with an MX1.25×5P straight pin header female port.

[0039] Continue reading Figure 1 and 2 In a preferred embodiment, the opening 11 is elliptical and protruding, and its inner wall has multiple grooves 111. The opening 11 needs to adhere to the skull surface of the experimental animal. The protruding and elliptical design of the opening 11 allows the electrode protective shell 10 to better adapt to the curve of the rat skull, reducing surgical incisions while enabling recording of multiple brain regions, ensuring more precise electrode positioning. Through precise electrode implantation, researchers can achieve efficient stimulation and recording of specific brain regions, thereby obtaining more accurate experimental data. The multiple grooves 111 on the inner wall of the opening 11 make the contact edge between the opening 11 and the skull surface irregular and rougher, improving adhesion stability. This design not only improves the adhesion stability of the protective shell 10 but also further reduces damage to the experimental animal's skull by dispersing pressure points. The elliptical protruding design of the opening 11, combined with the grooves 111, reduces the skull contact area by 15% while increasing adhesion strength by 40%. Preferably, the outer end of the opening 11 gradually narrows to minimize the contact area with the skull of the experimental animal.

[0040] Continue reading Figure 1 In another preferred embodiment, the protective shell 10 is integrally formed with a shield-shaped portion 101 and a square portion 102, which together form an accommodating space. The accommodating space of the protective shell 10 securely protects the USB adapter interface 15 and also prevents external damage and infection to the experimental animal. The shield-shaped portion 101 is arc-shaped, better conforming to the contour of the rat's head, while the square portion 102 facilitates connection to the USB adapter interface 15. Furthermore, the overall protective shell 10 is made of biocompatible plastic, ensuring the comfort and safety of the experimental animal after electrode implantation.

[0041] Continue reading Figure 3 Furthermore, in the above embodiment, the square portion 102 is provided with positioning holes 1021 to fix the USB conversion interface 15. Since the USB conversion interface 15 requires the use of an adapter board, which is plate-shaped, it can be installed using nickel-plated metal screws. The installation position of the adapter board is precisely calculated to ensure a stable connection with the electrodes.

[0042] See again Figure 1Alternatively, in the above embodiments, one end of the shielding shell 20 is provided with an insertion interface 2010. The insertion interface 2010 includes a shield-shaped plate 2011 and a square plate 2012 that are independent of each other. The shield-shaped plate 2011 fits the inner wall shape of the shield-shaped part 101, and the square plate 2012 fits the outer wall shape of the square part 102. The shielding shell 20 and the protective shell 10 are connected by insertion. Therefore, the insertion interface 2010 needs to fit the shape of the connection port 12. After insertion, the shield-shaped plate 2011 fits the inner wall of the shield-shaped part 101, and the square plate 2012 fits the outer wall of the square part 102. That is, the shield-shaped part 101 of the protective shell 10 and the square plate 2012 of the shielding shell 20 are exposed on the outside, while the square part 102 of the protective shell 10 and the shield-shaped plate 2011 of the shielding shell 20 are on the inside. The insertion interface 2010 and the connection port 12 are nested together, which effectively improves the stability of the insertion and makes it less prone to deformation.

[0043] Continue reading Figure 1 Furthermore, in the above embodiment, the shield-shaped portion 101 and the shield-shaped plate 2011 are provided with magnetic suction holes 30 for the neodymium magnet to pass through, and the shield-shaped plate 2011 and the protective shell 10 are magnetically fixed together. In addition to the plug-in structure, the protective shell 10 and the shielding shell 20 also employ a magnetic connection, enhancing the structural stability. In this way, even if the experimental animals collide during daily activities, the protective shell 10 will not shift, thus ensuring the continuity and accuracy of experimental data. Simultaneously, due to the magnetic force of the neodymium magnet, the connection process is simpler and faster, eliminating the need for complex mechanical fixation and reducing operation time and potential experimental errors.

[0044] See Figure 3 and Figure 4 In another preferred embodiment, the present invention further includes a protective cover 40, which is inserted into and closes the connection port 12. The protective shell 10 is connected to the shielding shell 20 or the protective cover 40. The protective cover 40 is used to close the protective shell 10, protecting the internal information acquisition components. During animal experiments, the protective shell 10 is connected to the shielding shell 20, and the USB interface 21 is connected to the USB conversion interface 15 for data transmission. During non-experimental periods, the USB interface 21 is unplugged from the USB conversion interface 15, and the protective shell 10 is connected to the protective cover 40, isolating the signal acquisition components from the outside world, thereby ensuring the stable operation of the information acquisition components and maintaining the health of the experimental animals.

[0045] Continue reading Figure 3 and Figure 4Furthermore, in the above embodiment, the protective cover 40 is provided with a cover plate 41 and an arc-shaped plate 42. The arc-shaped plate 42 is vertically disposed on the inner side of the cover plate 41, and the arc-shaped plate 42 fits the inner wall shape of the shield-shaped part 101. The cover plate 41 covers the connection port 12. When the protective cover 40 is inserted into the protective shell 10, the arc-shaped plate 42 fits against the inner wall of the shield-shaped part 101, and the cover plate 41 closes the connection port 12, further increasing the tightness and sealing between the protective cover 40 and the protective shell 10. The cover plate 41 is relatively thin, so the protective cover 40 does not increase the volume of the protective shell 10, minimizing the burden on the experimental animals.

[0046] See again Figure 1 and Figure 2 In another preferred embodiment, the shielding shell 20 includes a shielding shell 201 and a shielding shell cover 202. The shielding shell 201 is configured as a square tube, and the shielding shell cover 202 has a positioning part 2021 for positioning the data cable 22. The shielding shell 20 houses a USB interface 21 and a data cable 22. The USB interface 21 is flat, hence the shielding shell 20 is designed as a square tube with a matching shape. A connector 2010 is located at one end of the shielding shell 201, and the shielding shell cover 202 is inserted into the other end of the shielding shell 201. The positioning part 2021 of the shielding shell cover 202 can precisely fix the position of the data cable 22, avoiding friction and noise during rat movement and ensuring stable data transmission. The USB interface 21 is tightly connected to the data cable 22, and the flat design reduces volume and weight, thereby reducing the impact on the experimental animals. The entire shielding shell 20 has a robust structure while remaining lightweight, adapting to experimental animals of different sizes and species, and meeting the needs of long-term, continuous experiments.

[0047] See Figure 5 In another preferred embodiment, both the protective shell 10 and the shielding shell 20 are surrounded by an electromagnetic shielding layer. This electromagnetic shielding layer effectively prevents external electromagnetic interference from affecting the experimental data. This shielding layer not only improves the reliability of the experimental data but also provides a safer living environment for the experimental animals. The electromagnetic shielding layer can absorb and reduce electromagnetic waves from the outside, avoiding adverse effects on the animals while ensuring the purity of the experimental data.

[0048] I. The following is the manufacturing method of this utility model:

[0049] 1. Fabrication of electrode body 13:

[0050] A 2×2 pin array with a 1.27mm pitch was selected as the electrode holder.

[0051] Use curved-nose pliers to remove the diagonal pins from the 2×2 array in the same direction.

[0052] Prepare a nickel-chromium alloy electrode wire, select a length of 3-3.5cm, and cut it with scissors.

[0053] The electrode wire is bent in the middle and the two ends are inserted into the needle holes.

[0054] Insert the pin header back into the pin hole, in the same direction as the removal direction in step 2.

[0055] Use a multimeter to measure the continuity of the pin header and ensure good contact between the electrode wire and the pin header.

[0056] Fix the electrode holder to the corresponding female connector type, with the other end pointing vertically downwards, and rely on gravity to straighten the electrode wire and twist the electrode wire together.

[0057] Use a hot air gun to heat at 280℃ for about 10 seconds to shape.

[0058] After cooling, the electrode protrusion pins were fixed under a stereomicroscope using 502 super glue. The electrode length was then trimmed according to the depth requirements of the brain region coordinates and the actual requirements of the experiment.

[0059] Use a wire stripper to untangle the stranded threads at the end of the electrode wire, confirming that the distance between the two ends is approximately 0.5mm, or cut off one end and confirm that the distance between the two ends is approximately 0.5mm or 1 thread pitch. Confirm the position of the electrode pin at one end and mark it with a marker for later use.

[0060] 2. Make adapter terminal wire 14:

[0061] The adapter is an MX 1.25mm JST1.25-5P single-ended terminal wire housing. Select AWG 28 multi-core copper wire. Use cold-pressing pliers to install the crimping terminal. Insert the wires into the housing according to the required wire sequence. Select a 2×2P double-row pin socket on one side of the electrode end and solder the pins on the same side to the multi-core copper wire. If necessary, use hot melt glue to seal and protect.

[0062] 3. Make a USB adapter interface 15:

[0063] The protective case 10 and the USB conversion interface 15 are installed by nickel-plated metal screws. The outside of the protective case 10 is wrapped with copper tape or copper foil. On the USB conversion interface 15, the outer metal shell of the conversion interface, the flying wire of the reference skull nail and the copper foil are shorted.

[0064] II. The following is the surgical implantation procedure for this utility model:

[0065] This case study uses male (Sprague-Dawley) SD rats, weighing between 250-300g, for electrode implantation surgery.

[0066] Remove the skin from the implantation site, keep the bone surface clean, install the ground wire and reference cranial screw, and fix it with dental materials.

[0067] An opening is made in the skull of the target brain region, the meninges are removed, and the electrode body 13 is slowly implanted.

[0068] The electrode body 13 is simply fixed using a DMG temporary crown bridge. The tissue inside the opening is kept moist. Paraffin combined with KY lubricant can be used to protect and seal the cranial window opening. Then, the assembled adapter terminal 14 and USB conversion interface 15 are connected to the base pins of the electrode body 13.

[0069] The electrode body 13, together with the protective shell 10, is supported on the surface of the animal's skull. After confirming stability, dental cement is poured into the bottom of the module for uniform filling and sealing. Once the dental cement has hardened, the surgery is complete. Then, the protective shell 10 is sealed with the protective cap 40. Figure 6 As shown.

[0070] After observing and waiting for a period of time until the rat's condition stabilizes, connect the shielding shell 20 to the protective shell 10, connect the USB interface 21 to the USB conversion interface 15, and connect the data cable 22 through the shielding shell 20 to the host computer 50. Figure 5 As shown, electroencephalogram (EEG) or local field potential (LFP) signals are acquired according to the experimental requirements. During the acquisition process, ensure that the equipment parameters are set correctly, minimize signal interference, and guarantee data quality. After the experiment, seal the protective shell 10 with the protective cover 40.

[0071] The above description represents optional embodiments of this utility model. For those skilled in the art, modifications and improvements can be made without affecting the principles and effects of this utility model, including increasing the number of conversion interface channels and changing the interface model. These modifications and improvements should also be considered within the scope of protection of this utility model.

[0072] It should be noted that, in this document, relational terms such as "first" and "second" are used merely to distinguish one entity or operation from another, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Furthermore, the terms "comprising," "including," or any other variations thereof are intended to cover non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements includes not only those elements but also other elements not expressly listed, or elements inherent to such a process, method, article, or apparatus. Without further limitations, an element defined by the phrase "comprising one..." does not exclude the presence of other identical elements in the process, method, article, or apparatus that includes said element.

[0073] The above description is merely a specific embodiment of the present invention, enabling those skilled in the art to understand or implement the invention. Various modifications to these embodiments will be readily apparent to those skilled in the art, and the general principles defined herein may be implemented in other embodiments without departing from the spirit or scope of the invention. Therefore, the present invention is not to be limited to the embodiments shown herein, but is to be accorded the widest scope consistent with the principles and novel features claimed herein.

Claims

1. An electromagnetically shielded deep brain electrical stimulation and acquisition device for rats, characterized in that, include: The protective shell has an opening at the bottom and a connection port at the top. The opening is adhered and fixed to the surface of the animal's skull. Inside the protective shell are an electrode body, an adapter terminal line, and a USB conversion interface connected in sequence. The electrode body is implanted into the animal's brain through the opening. as well as, A shielding shell is inserted into the connection port. The shielding shell contains a USB interface and a preamplifier. The USB interface is connected to the USB conversion interface. The preamplifier is connected to the host computer via a data cable that passes through the shielding shell.

2. The electromagnetically shielded deep brain electrical stimulation and acquisition device for rats as described in claim 1, characterized in that, The opening is elliptical and protrudes, and the inner wall of the opening has multiple grooves.

3. The electromagnetically shielded deep brain electrical stimulation and acquisition device for rats as described in claim 1, characterized in that, The protective shell is integrally formed and has a shield-shaped part and a square part, which together form an accommodating space.

4. The electromagnetically shielded deep brain electrical stimulation and acquisition device for rats as described in claim 3, characterized in that, The square portion is provided with positioning holes to fix the USB conversion interface.

5. The electromagnetically shielded deep brain electrical stimulation and acquisition device for rats as described in claim 3, characterized in that, One end of the shielding shell is provided with an insertion interface, which includes a shield-shaped plate and a square plate that are independent of each other. The shield-shaped plate fits the inner wall shape of the shield-shaped part, and the square plate fits the outer wall shape of the square part.

6. The electromagnetically shielded deep brain electrical stimulation and acquisition device for rats as described in claim 5, characterized in that, The shield-shaped part and the shield-shaped plate are provided with magnetic holes for rubidium magnets to pass through, and the shield plate and the protective shell are magnetically fixed together.

7. The electromagnetically shielded deep brain electrical stimulation and acquisition device for rats as described in claim 3, characterized in that, It also includes a protective cover, which is inserted into the connection port and closes the connection port, and the protective shell is connected to the shielding shell or the protective cover.

8. The electromagnetically shielded deep brain electrical stimulation and acquisition device for rats as described in claim 7, characterized in that, The protective cover has a cover plate and an arc-shaped plate. The arc-shaped plate is vertically arranged on the inner side of the cover plate. The arc-shaped plate fits the inner wall shape of the shield-shaped part. The cover plate covers the connection port.

9. The electromagnetically shielded deep brain electrical stimulation and acquisition device for rats as described in claim 1, characterized in that, The shielding shell includes a shielding shell and a shielding shell cover. The shielding shell is configured as a square tube, and the shielding shell cover is provided with a positioning part for positioning the data cable.

10. The electromagnetically shielded deep brain electrical stimulation and acquisition device for rats as described in claim 1, characterized in that, Both the protective shell and the shielding shell are wrapped with an electromagnetic shielding layer on their outer periphery.

Images