A stirring device for heparin sodium production
By adopting a non-interfering stirring rod and extrusion plate design in the heparin sodium production unit, combined with the cooperation of the cleaning tank and the stirring tank, the problem of scraper wear was solved, achieving efficient stirring and convenient cleaning.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- BOZHOU JUNDA BIOTECHNOLOGY CO LTD
- Filing Date
- 2025-07-22
- Publication Date
- 2026-06-19
AI Technical Summary
In existing heparin sodium production equipment, the scraper and the mixing tank experience severe friction and wear, resulting in gaps that affect the removal of residues from the inner wall.
Design a mixing device for heparin sodium production, which uses non-interfering mixing rods and extrusion plates for mixing and scraping respectively. A cleaning tank is set up in conjunction with the mixing tank. During mixing, the extrusion plate is cleaned in the cleaning tank, and during scraping, the mixing rod is cleaned in the cleaning tank. The bottom support of the mixing tank facilitates the staggered addition of materials.
It enables independent operation of mixing and scraping, avoiding wear, simplifying equipment maintenance, and improving mixing efficiency and cleaning convenience.
Smart Images
Figure CN224371205U_ABST
Abstract
Description
Technical Field
[0001] This utility model belongs to the field of heparin sodium production technology, and in particular relates to a stirring device for heparin sodium production. Background Technology
[0002] Heparin sodium is an anticoagulant that interferes with many aspects of the blood clotting process. It has anticoagulant effects both in vivo and in vitro. Its mechanism of action is relatively complex. It mainly works by binding to antithrombin III (AT-III), thereby enhancing the latter's inhibitory effect on activated coagulation factors II, IX, X, XI, and XII. The consequences include preventing platelet aggregation and destruction, hindering the formation of thromboplastin-activating enzymes, preventing prothrombin from becoming thrombin, inhibiting thrombin, and thus preventing fibrinogen from becoming fibrin, thereby exerting an anticoagulant effect.
[0003] A search revealed that application number 202421594488.0 discloses a stirring device for heparin sodium production, comprising a fixed plate, two right-angled plates fixedly connected to the bottom surface of the fixed plate, a stirring tank fixedly connected to the upper surface of the fixed plate, two snap-fit plates fixedly connected to the upper surface of the fixed plate, and one side of each snap-fit plate being fixedly connected to the outer surface of the stirring tank. Each snap-fit plate has an electric push rod fixedly installed on its upper surface. The device features the following technical advantages: "The electric push rod supports the sealing cover, facilitating the injection of heparin sodium raw material into the stirring tank; the combined use of the drive motor, sealing cover, and sealing ring seals the connection between the stirring tank and the sealing cover; the combined use of bearings, spiral lifting blades, and mixing rods achieves thorough stirring of the heparin sodium raw material; and the combination of cleaning plates and scrapers facilitates cleaning of the inner wall of the stirring tank."
[0004] Although the scraper in this device can contact the inner wall of the mixing tank to remove the residue, the scraper adopts a fixed structure. During the mixing process, the overall area of the scraper is large, which increases the load on the mixing motor. At the same time, the outer side of the scraper is constantly in contact with the mixing tank during the mixing process, and the two will generate a certain amount of friction. When the wear reaches a certain level, a gap will exist between the two, which will prevent the scraper from removing the residue from the inner wall.
[0005] To address the aforementioned issues, this application proposes a stirring device for the production of heparin sodium. Utility Model Content
[0006] The purpose of this invention is to provide a stirring device for the production of heparin sodium, which solves the problems mentioned in the background art.
[0007] To solve the above-mentioned technical problems, this utility model is achieved through the following technical solution:
[0008] This utility model relates to a mixing device for heparin sodium production, comprising a lower frame and an upper frame located directly above the lower frame. The upper frame is equipped with a rotating switching seat, and a stirring rod and an extrusion plate are respectively installed at the lower end of the switching seat for stirring and scraping materials inside the mixing tank. The arc-shaped outer wall of the extrusion plate is in close contact with the inner wall of the mixing tank. The lower frame is provided with a cleaning tank that is level with the height of the mixing tank and can accommodate the stirring rod and the extrusion plate. Several electric cylinders are provided between the lower frame and the upper frame for lifting and lowering the upper frame and the switching seat.
[0009] Furthermore, an obstacle avoidance bracket is fixed to the top of the upper frame, and a switching motor is fixedly installed on the obstacle avoidance bracket to drive the switching seat to rotate.
[0010] Furthermore, a stirring motor is fixed to the upper end of the switching seat, the stirring rod is rotatably connected to the switching seat and fixed to the output end of the stirring motor, and the extrusion plate is fixedly installed to the switching seat through several extrusion rods.
[0011] Furthermore, the upper end of the mixing tank is provided with at least two positioning holes, and the bottom of the switching seat is fixed with a positioning pin that is inserted through the positioning holes.
[0012] Furthermore, a support base is installed on one side of the bottom of the lower frame, and the mixing tank is slidably placed on the support base. The support base includes a support frame fixed to the lower frame and a plurality of rollers rotatably connected to the support frame. A baffle plate located at the top of the rollers is fixed on the support frame.
[0013] Furthermore, a trapezoidal guide plate is fixed at the bottom side of the mixing tank, located directly below the positioning hole, and a trapezoidal guide groove is formed on the inner side of the baffle, which slides horizontally with the trapezoidal guide plate.
[0014] Furthermore, the bottom of the cleaning tank is connected to a drain pipe, and the bottom of the mixing tank is connected to a discharge pipe.
[0015] Furthermore, telescopic rods are installed between the four corners of the lower frame and the upper frame.
[0016] This utility model has the following beneficial effects:
[0017] This utility model is equipped with a stirring rod and an extrusion plate on the switching seat for switching, which respectively play the roles of stirring and scraping. The two do not interfere with each other and can ensure their respective performance during use. The stirring process will not cause additional wear to the extrusion plate.
[0018] This invention features a cleaning tank and a mixing drum that work in conjunction with a mixing rod and an extrusion plate. When the mixing drum is agitated by the mixing rod, the extrusion plate is cleaned in the cleaning tank; conversely, when the extrusion plate scrapes the material, the mixing rod is cleaned in the cleaning tank, facilitating the cleaning and maintenance of the mixing equipment.
[0019] The support base at the bottom of the mixing tank in this invention facilitates short-distance pulling of the mixing tank to create a misalignment with the mixing rod, thereby making it easier to add the material to be mixed.
[0020] Of course, any product implementing this utility model does not necessarily need to achieve all of the advantages described above at the same time. Attached Figure Description
[0021] To more clearly illustrate the technical solutions of the embodiments of this utility model, the accompanying drawings used in the description of the embodiments will be briefly introduced below. Obviously, the drawings described below are only some embodiments of this utility model. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.
[0022] Figure 1 This is a schematic diagram of the overall structure of this utility model;
[0023] Figure 2 for Figure 1 A schematic diagram of the structure for switching between the stirring rod and the extrusion plate;
[0024] Figure 3 for Figure 2 A structural schematic diagram viewed from below after the upper and middle frames have been lowered.
[0025] Figure 4 A schematic diagram showing the disassembled structure of the support base and mixing tank;
[0026] The attached diagram lists the components represented by each number as follows:
[0027] In the diagram: 1. Lower frame; 2. Upper frame; 21. Clearance bracket; 3. Switching seat; 31. Stirring rod; 311. Stirring motor; 32. Extrusion plate; 321. Extrusion rod; 33. Switching motor; 34. Positioning pin; 4. Cleaning tank; 41. Drain pipe; 5. Support seat; 51. Support frame; 52. Roller; 53. Baffle; 54. Trapezoidal guide groove; 6. Stirring tank; 61. Positioning hole; 62. Trapezoidal guide plate; 63. Discharge pipe; 7. Electric cylinder; 8. Telescopic rod. Detailed Implementation
[0028] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the scope of protection of the present utility model.
[0029] In the description of this utility model, it should be understood that the terms "opening", "upper", "lower", "thickness", "top", "middle", "length", "inner", "around" and other terms indicating orientation or positional relationship are only for the convenience of describing this utility model and simplifying the description, and do not indicate or imply that the components or elements referred to must have a specific orientation, or be constructed and operated in a specific orientation, and therefore should not be construed as a limitation of this utility model.
[0030] Please see Figure 1 - Figure 4 As shown, this utility model is a stirring device for heparin sodium production, including a lower frame 1 and an upper frame 2 located directly above the lower frame 1. The upper frame 2 is provided with a rotating switching seat 3. The lower end of the switching seat 3 is respectively equipped with a stirring rod 31 and a pressing plate 32 for stirring and scraping the material inside the stirring tank 6. The arc-shaped outer wall of the pressing plate 32 is in close contact with the inner wall of the stirring tank 6. In this embodiment, by setting the stirring rod 31 and the pressing plate 32 to be non-interfering with each other, they are used for stirring and scraping respectively, ensuring their respective performance and preventing wear on the pressing plate during stirring.
[0031] Furthermore, the lower frame 1 is equipped with a cleaning tank 4 that is level with the mixing tank 6 and can respectively accommodate the mixing rod 31 and the extrusion plate 32. Through the cooperative design of the cleaning tank 4 and the mixing tank 6, the extrusion plate 32 is cleaned in the cleaning tank 4 during mixing, and the mixing rod 31 is cleaned in the cleaning tank 4 during scraping, which facilitates equipment maintenance.
[0032] Furthermore, several electric cylinders 7 are provided between the lower frame 1 and the upper frame 2 for lifting and lowering the upper frame 2 and the switching seat 3. At least two electric cylinders 7 are arranged symmetrically.
[0033] Specifically, an obstacle avoidance bracket 21 is fixed on the top of the upper frame 2, and a switching motor 33 is fixedly installed on the obstacle avoidance bracket 21 to drive the switching seat 3 to rotate; a stirring motor 311 is fixed on the upper end of the switching seat 3, the stirring rod 31 is rotatably connected to the switching seat 3 and fixed to the output end of the stirring motor 311, and the extrusion plate 32 is fixedly installed to the switching seat 3 through several extrusion rods 321.
[0034] Furthermore, in order to prevent the mixing tank 6 from rotating with the stirring rod 31 when the material inside the mixing tank 6 is stirred, the upper end of the mixing tank 6 is provided with at least two positioning holes 61, and the bottom of the switching seat 3 is fixed with a positioning pin 34 that is inserted through the positioning hole 61. In this embodiment, when the stirring rod 31 enters the mixing tank 6 from top to bottom, the positioning pin 34 is inserted downwards into the positioning pin 34, thereby increasing the circumferential positioning of the mixing tank 6 during stirring.
[0035] Furthermore, in order to facilitate the separation of the mixing tank 6 and the mixing rod 31 and the addition of materials, a support base 5 is installed on one side of the bottom of the lower frame 1. The mixing tank 6 is slidably placed on the support base 5. The support base 5 includes a support frame 51 fixed to the lower frame 1 and a plurality of rollers 52 rotatably connected in the support frame 51. A baffle 53 located at the top of the rollers 52 is fixed on the support frame 51. The baffle 53 is used to restrict the movement path of the mixing tank 6.
[0036] When in use, the mixing bowl 6 is placed on the roller 52, such as... Figure 4 As shown, when the mixing tank 6 is located on the left side inside the baffle 53, the mixing tank 6 is located at the mixing station; when the mixing tank 6 is located on the right side inside the baffle 53, the mixing tank 6 is located at the feeding station, and the mixing tank 6 and the mixing rod 31 are in a staggered state.
[0037] Furthermore, a trapezoidal guide plate 62 is fixed at the bottom side of the mixing tank 6, located directly below the positioning hole 61, and a trapezoidal guide groove 54 is formed on the inner side of the baffle 53, which slides horizontally with the trapezoidal guide plate 62.
[0038] The upper ends of the trapezoidal guide plate 62 and the trapezoidal guide groove 54 are both smaller than the lower ends, so the mixing tank 6 will not be pulled off the support base 5 during the upward lifting force. More specifically, it makes it easier for the extrusion plate 32 to be taken out from the inside of the mixing tank 6.
[0039] When installing the mixing tank 6 and the support base 5, the trapezoidal guide groove 54 and the support frame 51 can be fixed with bolts. First, place the mixing tank 6 on the roller 52, and then place the trapezoidal guide groove 54 to ensure that the trapezoidal guide groove 54 can be stably matched with the trapezoidal guide plate 62. At the same time, the bolts facilitate the assembly and disassembly of the mixing tank 6 on the support base 5.
[0040] To facilitate the discharge of cleaning fluid and the feeding of materials into the mixing tank 6, the bottom of the cleaning tank 4 is connected to a drain pipe 41, and the bottom of the mixing tank 6 is connected to a discharge pipe 63.
[0041] In use, valves (not shown in the figure) are installed in the drain pipe 41 on the cleaning tank 4 and the discharge pipe 63 on the mixing tank 6. The cleaning liquid is injected into the cleaning tank 4, and the discharge pipe 63 is connected to the discharge pipe to the external tank or the next process.
[0042] To ensure the stability of the upper frame 2 during lifting, telescopic rods 8 are installed between the four corners of the lower frame 1 and the upper frame 2. The lower end of the telescopic rods 8 is fixed to the lower frame 1, and the upper end is fixed to the upper frame 2.
[0043] Understandably, this utility model features a non-interfering stirring rod and an extrusion plate on the switching base, used for stirring and scraping respectively, ensuring their respective performance and preventing wear on the extrusion plate during stirring. Through the coordinated design of the cleaning tank and the stirring tank, the extrusion plate is cleaned in the cleaning tank during stirring, and the stirring rod is cleaned in the cleaning tank during scraping, facilitating equipment maintenance. At the same time, the support base at the bottom of the stirring tank allows for short-distance pulling of the stirring tank to offset it from the stirring rod, making it convenient to add materials.
[0044] One specific application of this embodiment is:
[0045] like Figure 2 In the indicated state, pull the mixing tank 6 outward on the support base 5 until it is offset from the mixing rod 31. Then add materials to the mixing tank 6. After adding materials, push the mixing tank 6 back directly under the mixing rod 31. The electric cylinder 7 drives the upper frame 2 to move down. The mixing rod 31 enters the mixing tank 6. The two positioning pins 34 are inserted into the two positioning holes 61 respectively. After starting the mixing motor 311, the mixing rod 31 works and mixes the materials inside the mixing tank 6.
[0046] After mixing is completed, the electric cylinder 7 drives the upper frame 2 to move upward, the mixing rod 31 moves upward in the mixing tank 6, and the positioning pin 34 disengages from the positioning hole 61. At this time, the starter 23 drives the switching seat 3 to rotate 180° on the upper frame 2. After rotation, the mixing rod 31 is located above the cleaning tank 4, and the extrusion plate 32 is located above the mixing tank 6 and is concentric. The valve on the discharge pipe 63 is opened. When the electric cylinder 7 drives the upper frame 2 to move downward, the extrusion plate 32 enters the mixing tank 6 and scrapes the residue on the inner wall downward. After the electric cylinder 7 moves downward, the mixing rod 31 enters the cleaning tank 4. After starting the mixing motor 311, the mixing rod 31 can be automatically cleaned.
[0047] When the extrusion plate 32 is completely lowered to the bottom of the inner side of the mixing tank 6, the electric cylinder 7 drives the upper frame 2 to move upward, and the extrusion plate 32 moves upward from the mixing tank 6. Since the lower part of the trapezoidal guide plate 62 is larger than the upper part, and the trapezoidal guide plate 62 is located in the trapezoidal guide groove 54, when the extrusion plate 32 moves upward, it will not cause the mixing tank 6 to detach from the support seat 5. Until the extrusion plate 32 is completely removed, the single stirring work of the heparin sodium production process can be completed.
[0048] In the description of this specification, references to terms such as "an embodiment," "example," "specific example," etc., indicate that a specific feature, structure, material, or characteristic described in connection with that embodiment or example is included in at least one embodiment or example of the present invention. In this specification, the illustrative expressions of the above terms do not necessarily refer to the same embodiment or example. Furthermore, the specific features, structures, materials, or characteristics described may be combined in any suitable manner in one or more embodiments or examples.
[0049] The preferred embodiments of this utility model disclosed above are merely illustrative of the present utility model. These preferred embodiments do not exhaustively describe all details, nor do they limit the utility model to the specific implementations described. Clearly, many modifications and variations can be made based on the content of this specification. This specification selects and specifically describes these embodiments to better explain the principles and practical applications of this utility model, thereby enabling those skilled in the art to better understand and utilize it. This utility model is limited only by the claims and their full scope and equivalents.
Claims
1. A stirring device for producing heparin sodium, comprising a lower frame (1) and an upper frame (2) located directly above the lower frame (1), characterized in that: The upper frame (2) is provided with a rotating switching seat (3). The lower end of the switching seat (3) is respectively equipped with a stirring rod (31) and a pressing plate (32) for stirring and scraping the material inside the mixing tank (6). The outer arc wall of the pressing plate (32) is in close contact with the inner wall of the mixing tank (6). The lower frame (1) is provided with a cleaning tank (4) that is level with the height of the mixing tank (6) and can respectively accommodate the stirring rod (31) and the pressing plate (32). Several electric cylinders (7) are provided between the lower frame (1) and the upper frame (2) for lifting the upper frame (2) and the switching seat (3).
2. The stirring equipment for producing heparin sodium according to claim 1, characterized in that: The upper frame (2) is fixed with an obstacle avoidance bracket (21), and a switching motor (33) is fixedly installed on the obstacle avoidance bracket (21) to drive the switching seat (3) to rotate.
3. The stirring equipment for producing heparin sodium according to claim 1, characterized in that: The upper end of the switching seat (3) is fixed with a stirring motor (311), the stirring rod (31) is rotatably connected to the switching seat (3) and fixed to the output end of the stirring motor (311), and the extrusion plate (32) is fixedly installed to the switching seat (3) through several extrusion rods (321).
4. The stirring equipment for producing heparin sodium according to claim 1, characterized in that: The mixing tank (6) has at least two positioning holes (61) at its upper end, and the bottom of the switching seat (3) is fixed with a positioning pin (34) that is inserted through the positioning holes (61).
5. The stirring equipment for producing heparin sodium according to claim 1, characterized in that: A support base (5) is installed on one side of the bottom of the lower frame (1). The mixing tank (6) is slidably placed on the support base (5). The support base (5) includes a support frame (51) fixed to the lower frame (1) and a plurality of rollers (52) rotatably connected in the support frame (51). A baffle (53) located on the top of the rollers (52) is fixed on the support frame (51).
6. The stirring equipment for producing heparin sodium according to claim 5, characterized in that: The bottom side of the mixing tank (6) is fixed with a trapezoidal guide plate (62) located directly below the positioning hole (61), and the inner side of the baffle (53) forms a trapezoidal guide groove (54) that slides horizontally with the trapezoidal guide plate (62).
7. The stirring equipment for producing heparin sodium according to claim 1, characterized in that: The bottom of the cleaning tank (4) is connected to a drain pipe (41), and the bottom of the mixing tank (6) is connected to a discharge pipe (63).
8. The stirring equipment for producing heparin sodium according to claim 1, characterized in that: Telescopic rods (8) are installed between the four corners of the lower frame (1) and the upper frame (2).