An automated antigen preparation mixer

Abstract

The utility model discloses an antigen preparation automation mixer relates to mechanical engineering technical field, including mixing bucket, the inside of mixing bucket is provided with the through column, the outside of through column is provided with the stirring board, the top of mixing bucket is provided with the feed pipe, the outside fixedly connected with a plurality of connecting blocks on the top of through column, every connecting block is close to the side of first column rod and is provided with first threaded rod, every two second column rod is provided with the cleaning plate away from the center of mixing bucket, and the side end fixedly connected with round plate of every second column rod, the top fixedly connected with the limit block of every round plate, and the outside of every second column rod is provided with the spring. Mechanism adopts mechanical drive principle, improves traditional antigen preparation automation mixer, improves the performance of traditional antigen preparation automation mixer protection cleaning plate with additional structure, prevents long -term friction and causes the surface wear and tear of cleaning plate and bucket wall, and expands equipment service life.

Description

Technical Field

[0001] This utility model relates to the field of mechanical engineering technology, specifically to an automated mixer for antigen preparation. Background Technology

[0002] An antigen is a molecule or substance that can trigger an immune response. When an antigen enters an organism, it is recognized by the immune system as a foreign substance and triggers a series of immune responses to clear these foreign substances.

[0003] An automated antigen preparation mixer is a device specifically designed for biotechnology and medical research, primarily used to automate the mixing steps in the preparation of antigens (molecules that can trigger an immune response).

[0004] However, existing automated antigen preparation mixers have the following shortcomings:

[0005] In traditional automated antigen preparation mixers, the cleaning plate is usually fixed inside the mixing tank or on the stirring device. It stays in close contact with the tank wall during the mixing process to prevent material from adhering. However, if the pressure between the cleaning plate and the tank wall is too high or the contact is too tight during the mixing stage, it can cause the following problems: long-term friction will lead to wear on the surface of the cleaning plate and the tank wall, shortening the service life of the equipment. Utility Model Content

[0006] The purpose of this invention is to solve the problems mentioned in the background art in existing equipment. By setting up a cleaning mechanism, the first column slides on the side end of the through column, the first threaded rod locks its position after sliding, the first arc plate drives the second column to compress the spring, the spring deforms, and the outer side of the cleaning plate contacts and slightly adheres to the inner wall of the mixing tank.

[0007] To achieve the above objectives, the present invention adopts the following technical solution: an automated antigen preparation mixer, comprising a mixing tank, a through column inside the mixing tank, a stirring plate outside the through column, a feed pipe at the top of the mixing tank, a cleaning mechanism inside the mixing tank, and a filtering mechanism inside the feed pipe.

[0008] The cleaning mechanism includes multiple first arc-shaped plates and multiple second columns. A first column is fixedly connected to the outer side of each first arc-shaped plate. Multiple connecting blocks are fixedly connected to the outer side of the column. A first threaded rod is provided on the side of each connecting block near the first column. A cleaning plate is provided at the center of every two second columns away from the mixing tank. A circular plate is fixedly connected to the side end of each second column. A limit block is fixedly connected to the top of each circular plate. A spring is provided on the outer side of each second column.

[0009] Preferably, one side of each spring is fixedly connected to the side end of the circular plate, and the other side of each spring is fixedly connected to the inside of the stirring plate. The outside of the first column rod is slidably connected to the inside of the connecting block above the through column.

[0010] Preferably, a motor is provided at the top of the mixing tank, a first gear is provided at the output shaft of the motor, and a second gear is provided on the outside above the through column, with the side end of the second gear meshing with the side end of the first gear.

[0011] Preferably, a limiting plate is provided on the outside of the column, the side end of the limiting plate is rotatably connected to the inside of the mixing tank above, a discharge pipe is provided at the bottom of the mixing tank, a bracket is provided on the outside of the middle of the mixing tank, and a controller is provided on the top of the bracket.

[0012] Preferably, the filtration mechanism includes a filter screen, with two second arc-shaped plates arranged on the left and right outer sides of the filter screen. A third arc-shaped plate is fixedly connected to the side end of each second arc-shaped plate, and the side ends of each second arc-shaped plate and the third arc-shaped plate are slidably connected inside the feed pipe.

[0013] Preferably, a plate is provided on the top of each second arc-shaped plate and the top of the third arc-shaped plate, and a second threaded rod is provided on the top of each plate.

[0014] Compared with the prior art, the advantages and positive effects of this utility model are as follows:

[0015] 1. In this utility model, by setting a cleaning mechanism, the first column slides on the side end of the through column, the first threaded rod locks its position after sliding, the first arc plate drives the second column to compress the spring, the spring deforms, and the outer side of the cleaning plate contacts and slightly adheres to the inner wall of the mixing tank. The mechanism adopts the mechanical transmission principle, improves the traditional automated antigen preparation mixer, and uses the additional structure to improve the performance of the traditional automated antigen preparation mixer in protecting the cleaning plate, preventing long-term friction from causing wear on the surface of the cleaning plate and the tank wall, and extending the service life of the equipment.

[0016] 2. In this utility model, by setting a filtration mechanism, the second arc plate and the third arc plate slide inside the feed pipe, the second threaded rod locks the position of the plates, and a detachable filter screen is set to facilitate more precise filtration. The filter screen can intercept particulate matter and prevent it from entering the mixing tank. Attached Figure Description

[0017] Figure 1 A three-dimensional view of the main structure of an automated antigen preparation mixer is provided for this utility model;

[0018] Figure 2 A bottom-view perspective view of the main body structure of an automated antigen preparation mixer is provided for this utility model;

[0019] Figure 3 A three-dimensional cross-sectional view of the mixing tank of an automated antigen preparation mixer is provided for this utility model.

[0020] Figure 4 A three-dimensional cross-sectional view of the through-column and stirring plate of an automated mixer for antigen preparation is provided for this utility model;

[0021] Figure 5 A three-dimensional view of the connecting block structure of an automated antigen preparation mixer is provided for this utility model;

[0022] Figure 6 A three-dimensional cross-sectional view of the stirring plate of an automated mixer for antigen preparation is provided for this utility model;

[0023] Figure 7 This invention provides a three-dimensional cross-sectional view of the feed pipe of an automated mixer for antigen preparation.

[0024] In the diagram: 1. Mixing tank; 2. Feed pipe; 3. Cleaning mechanism; 31. First arc-shaped plate; 32. First column rod; 33. Connecting block; 34. First threaded rod; 35. Second column rod; 36. Cleaning plate; 37. Circular plate; 38. Limiting block; 39. Spring; 310. Limiting plate; 4. Filtering mechanism; 41. Filter screen; 42. Second arc-shaped plate; 43. Third arc-shaped plate; 44. Plate; 45. Second threaded rod; 5. Motor; 6. First gear; 7. Through column; 8. Second gear; 9. Controller; 10. Stirring plate; 11. Discharge pipe; 12. Support. Detailed Implementation

[0025] To make the technical means, creative features, objectives, and effects of this utility model easier to understand, the following describes this utility model in conjunction with specific embodiments:

[0026] like Figure 1 -Appendix Figure 7The diagram shows a mixing tank 1, with a through column 7 inside and a stirring plate 10 outside the through column 7. A feed pipe 2 is located at the top of the mixing tank 1. A cleaning mechanism 3 is installed inside the mixing tank 1, and a filtering mechanism 4 is installed inside the feed pipe 2. The cleaning mechanism 3 includes multiple first arc-shaped plates 31 and multiple second rods 35. A first rod 32 is fixedly connected to the outer side of each first arc-shaped plate 31. Multiple connecting blocks 33 are fixedly connected to the outer side of the through column 7. A first threaded rod 34 is provided on the side of each connecting block 33 near the first rod 32. A cleaning plate 36 is located between every two second rods 35 away from the center of the mixing tank 1. A circular plate 37 is fixedly connected to the side end of each second rod 35, and a limit block 38 is fixedly connected to the top of each circular plate 37. Each second column 35 is provided with a spring 39 on its outside. One side of each spring 39 is fixedly connected to the side end of the circular plate 37, and the other side of each spring 39 is fixedly connected to the inside of the stirring plate 10. The outside of the first column 32 is slidably connected to the inside of the connecting block 33 above the through column 7. A motor 5 is provided at the top of the mixing tank 1. A first gear 6 is provided at the output shaft of the motor 5. A second gear 8 is provided on the outside of the through column 7. The side end of the second gear 8 meshes with the side end of the first gear 6. A limit plate 310 is provided on the outside of the through column 7. The side end of the limit plate 310 is rotatably connected to the inside of the mixing tank 1 above. A discharge pipe 11 is provided at the bottom of the mixing tank 1. A bracket 12 is provided on the outside of the middle part of the mixing tank 1. A controller 9 is provided on the top of the bracket 12.

[0027] The overall effect of Embodiment 1 is as follows: the relevant components can improve the performance of the cleaning plate of the traditional automated antigen preparation mixer through mechanical transmission. The function of setting the limiting block 38 is to limit the movement of the first arc plate 31. The function of setting the connecting block 33 is to lock the position of the first column rod 32 after it has moved. This mechanical transmission method prevents long-term friction from causing wear on the surface of the cleaning plate and the barrel wall, thus extending the service life of the equipment.

[0028] Example 2, as Figures 1-7 As shown, the filtration mechanism 4 includes a filter screen 41. Two second arc-shaped plates 42 are arranged on the left and right outer sides of the filter screen 41. A third arc-shaped plate 43 is fixedly connected to the side end of each second arc-shaped plate 42. The side ends of each second arc-shaped plate 42 and the side ends of the third arc-shaped plate 43 are slidably connected inside the feed pipe 2. A plate 44 is arranged on the top of each second arc-shaped plate 42 and the top of the third arc-shaped plate 43. A second threaded rod 45 is arranged on the top of each plate 44.

[0029] The effect achieved by the entire embodiment 2 is as follows: by setting the filter mechanism 4, the second arc plate 42 and the third arc plate 43 slide inside the feed pipe 2, the second threaded rod 45 locks the position of its plate 44, and a detachable filter screen 41 is set to facilitate more precise filtration. The filter screen 41 can intercept particulate matter and prevent it from entering the mixing tank 1.

[0030] The working principle of the entire equipment is as follows: Installation and inspection phase: Before starting the test, ensure that all parts of the structure are in a stable state to prevent any part of the structure from malfunctioning after the work is completed.

[0031] Cleaning the mixing tank stage: Water is injected into the feed pipe 2, and then the feed pipe 2 is blocked with an external tool cover to prevent liquid from flowing out during mixing and cleaning. At this time, the operator rotates the first threaded rod 34 to release the positioning of the first threaded rod 34 on the first column rod 32, and then pulls the first column rod 32 outward. The first column rod 32 drives the first arc plate 31 to move inside the through column 7. The first arc plate 31 drives the second column rod 35 to slide inside the mixing plate 10. At the same time, the second column rod 35 drives the circular plate 37 to slide inside the mixing plate 10. The limiting block 38 slides inside the mixing plate 10. At this time, the spring 39 deforms. As the second column rod 35 slides, it drives the outer side of the cleaning plate 36 to fit against the inner side of the mixing tank 1. The first threaded rod 34 is rotated again to lock the position of the first column rod 32 after it has moved. At this time, the controller 9 starts the motor 5. The output shaft of the motor 5 drives the first gear 6 to rotate. The first gear 6 rotates and meshes with the side end of the second gear 8. The second gear 8 drives the through column 7 and the limiting plate 310 to rotate. The through column 7 drives the stirring plate 10 and the cleaning plate 36 to clean and scrape the inner wall of the mixing tank 1. Then the discharge pipe 11 is opened to discharge the waste liquid. When preparing antigen, the operation of the first column rod 32 is reversed. The cleaning plate 36 is moved away from the inner wall of the mixing tank 1. Then the feed pipe 2 is used to mix and feed the material. The motor 5 is started again and the above operation is repeated. The mixed antigen is discharged from the discharge pipe 11.

[0032] During the disassembly or installation of the filter screen: When disassembling the filter screen 41, rotate the second threaded rod 45 to release the positioning of the plate 44, and then move the second arc plate 42 and the third arc plate 43 to move the filter screen 41 out of the feed pipe 2. When installing the filter screen 41, the above operations are performed in reverse.

[0033] The above description is merely a preferred embodiment of the present utility model and is not intended to limit the present utility model in any other way. Any person skilled in the art may make changes or modifications to the above-disclosed technical content to create equivalent embodiments for application in other fields. However, any simple modifications, equivalent changes, and modifications made to the above embodiments based on the technical essence of the present utility model without departing from the technical solution of the present utility model shall still fall within the protection scope of the technical solution of the present utility model.

Claims

1. An automated mixer for antigen preparation, characterized in that: The mixture includes a mixing tank (1), a through column (7) is provided inside the mixing tank (1), a stirring plate (10) is provided outside the through column (7), a feed pipe (2) is provided at the top of the mixing tank (1), a cleaning mechanism (3) is installed inside the mixing tank (1), and a filter mechanism (4) is installed inside the feed pipe (2). The cleaning mechanism (3) includes multiple first arc-shaped plates (31) and multiple second columns (35). A first column (32) is fixedly connected to the outer side of each first arc-shaped plate (31). Multiple connecting blocks (33) are fixedly connected to the outer side above the through column (7). A first threaded rod (34) is provided on the side of each connecting block (33) near the first column (32). A cleaning plate (36) is provided at the center of each pair of second columns (35) away from the mixing tank (1). A circular plate (37) is fixedly connected to the side end of each second column (35). A limit block (38) is fixedly connected to the top of each circular plate (37). A spring (39) is provided on the outer side of each second column (35).

2. The automated antigen preparation mixer according to claim 1, characterized in that: One side of each spring (39) is fixedly connected to the side end of the circular plate (37), and the other side of each spring (39) is fixedly connected to the inside of the stirring plate (10). The outside of the first rod (32) is slidably connected to the inside of the connecting block (33) above the through column (7).

3. The automated antigen preparation mixer according to claim 1, characterized in that: A motor (5) is provided on the top of the mixing tank (1), a first gear (6) is provided at the output shaft of the motor (5), and a second gear (8) is provided on the outside of the through column (7), with the side end of the second gear (8) meshing with the side end of the first gear (6).

4. The automated antigen preparation mixer according to claim 1, characterized in that: The outside of the through column (7) is provided with a limiting plate (310), the side end of the limiting plate (310) is rotatably connected to the inside above the mixing tank (1), the bottom of the mixing tank (1) is provided with a discharge pipe (11), the outside of the middle part of the mixing tank (1) is provided with a bracket (12), and the top of the bracket (12) is provided with a controller (9).

5. The automated antigen preparation mixer according to claim 1, characterized in that: The filtration mechanism (4) includes a filter screen (41). Two second arc-shaped plates (42) are provided on the left and right outer sides of the filter screen (41). A third arc-shaped plate (43) is fixedly connected to the side end of each second arc-shaped plate (42). The side ends of each second arc-shaped plate (42) and the side ends of the third arc-shaped plate (43) are slidably connected inside the feed pipe (2).

6. The automated antigen preparation mixer according to claim 5, characterized in that: Each of the second arc-shaped plates (42) and the third arc-shaped plates (43) is provided with a plate (44), and each of the plate (44) is provided with a second threaded rod (45) at its top.

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