New transdermal patch production equipment
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-12-31
- Publication Date
- 2026-06-30
Smart Images
Figure CN224421525U_ABST
Abstract
Description
Technical Field
[0001] This utility model relates to the field of auxiliary equipment for drug production, and in particular to a novel transdermal patch production device. Background Technology
[0002] Transdermal patches are a type of drug delivery system that is applied to the surface of intact skin. When using a transdermal patch, the user peels off the protective film and applies it to the outer side of the skin. The drug is then delivered through the skin barrier into the bloodstream to exert a systemic effect. This transdermal patch delivery method allows drug absorption to be unaffected by factors such as pH in the digestive tract, food, and transit time, and also avoids the first-pass effect of the liver. Transdermal patches offer flexible dosing options, allowing for long-term administration or discontinuation at any time, making them particularly suitable for infants, children, and the elderly with limited swallowing ability who have poor medication adherence.
[0003] Existing transdermal patches vary in type. Some have a layer of medication adhered to the inner surface of the transdermal patch (usually non-woven fabric) (the entire inner side of the transdermal patch is on a single plane), while others have a layer of medication protruding from the inner surface of the transdermal patch adhered to the middle of its inner side through methods such as heating. Utility Model Content
[0004] This invention provides a novel transdermal patch production device with advantages of compact structure, ease of use, and low cost.
[0005] The technical solution adopted by this utility model to solve its technical problem is:
[0006] A novel transdermal patch production apparatus includes an electric chain conveyor, an electric heating mechanism, a spraying mechanism, a pressing mechanism, an oil supply mechanism, an air compressor, and a workbench. A fixed plate is mounted on the rear frame of the electric chain conveyor. The electric heating mechanism includes a raw material hopper, an electric rotary conveying valve, a vibrating motor, electric heating plates, and a temperature switch. A discharge port is installed at the lower end of the raw material hopper, and the inlet pipe of the electric rotary conveying valve is connected to the lower end of the discharge port. The outer end of the raw material hopper has a hollow heating chamber, inside which multiple electric heating plates are installed. The vibrating motor and temperature switch are fixedly installed on the outer end of the heating chamber. The rear outer end of the heating chamber is mounted on the front end of the fixed plate. The spraying mechanism is mounted on the frame of the electric chain conveyor. The pressing mechanism and the oil supply mechanism are respectively mounted on the rear front ends of the workbench. The workbench is mounted on the side end of the electric chain conveyor.
[0007] Furthermore, the spraying mechanism includes a spray pipe and a valve. A spray nozzle is installed at the lower end of the spray pipe, the lower end of the outlet pipe of the valve is installed on the spray pipe, the inlet pipe of the valve and the tap water pipe are connected by a pipeline, and the spray pipe is installed on a frame.
[0008] Furthermore, the pressure plate mechanism includes a cylinder and a pressure plate. An inlet pipe is installed at the upper end of the pressure plate, a sponge is sleeved inside the pressure plate, and multiple oil seepage holes are distributed at the lower end of the pressure plate. The cylinder barrel is installed on one side of the fixed plate of the workbench.
[0009] Furthermore, the oil supply mechanism includes an oil tank, valve A, and a one-way air valve. An oil outlet pipe is installed at the lower end of the oil tank and is connected to the upper end of valve A. A connecting pipe is installed at the lower outlet of valve A. The lower end of the connecting pipe and the upper end of the inlet pipe are connected by a flexible hose with a length allowance. The air inlet pipe of the one-way air valve is installed outside the upper end of the oil tank. The oil tank is installed on the other side of the fixed plate of the workbench.
[0010] Furthermore, the electric heating plate is a PTC electric heating plate.
[0011] Compared with existing technologies, the advantages of this invention are as follows: During production, workers place the transdermal patch at the bottom of the raw material hopper. With a simple power switch operation, the pre-prepared medication, melted in the raw material hopper and controlled by an electrically operated rotary conveying valve, is automatically and quantitatively spread onto the transdermal patch. After cooling by water mist sprayed by a spraying mechanism, the medication is then pressed flat by a pressure plate mechanism to obtain the finished transdermal patch. This invention ensures product quality (the amount of medication entering the transdermal patch is easily controlled) and minimizes the labor intensity of workers, providing convenience and improving production efficiency. In summary, this invention has good application prospects. Attached Figure Description
[0012] Figure 1 This is a schematic diagram of the structure of this utility model;
[0013] Figure 2 This is a partial structural schematic diagram of the present invention;
[0014] Figure 3 This is the circuit diagram of this utility model. Detailed Implementation
[0015] Figures 1-3As shown, the novel transdermal patch production device includes an electric chain conveyor M, a power module T1, an electric heating mechanism, a spraying mechanism, a pressure plate mechanism, an oil supply mechanism, an air compressor (not shown in the figure), a power switch, and a workbench 1. The lower left end of the electric chain conveyor M is higher than the right end (water remaining on the chain flows out to the right end). A fixed plate 2 is welded to the frame of the electric chain conveyor. The electric heating mechanism includes a raw material silo 31 (open at the top and conical at the bottom), an electric rotary conveying valve M1, a vibration motor M3, an electric heating plate RT, and a temperature switch W. A discharge port, communicating with the interior, is welded to the lower center of the raw material silo 31. The lower end of the inlet pipe of the electric rotary conveying valve M1 is connected to the lower end of the discharge port via a pipe joint. The lower end of the discharge pipe of the electric rotary conveying valve M1 has a conical open structure. The raw material silo... The outer end is a hollow two-layer structure serving as a heating chamber 311. Multiple electric heating plates RT are fixedly installed inside the heating chamber 311, and the upper end of the heating chamber 311 is a closed structure. The vibration motor M2 is fixedly installed in the middle of the outer front end of the heating chamber 311. The temperature switch W is fixedly installed in the outer front end of the heating chamber 311, with its temperature sensing surface in close contact with the outer front end of the heating chamber 311. The outer rear end of the heating chamber 311 is welded to the upper left side of the front end of the fixed plate 2. The spray mechanism is installed on the frame 3 of the electric chain conveyor. The pressure plate mechanism and the oil supply mechanism are respectively installed on the front sides of the mounting plate at the rear of the workbench 1. The power module T1 has four power switches installed in the component box 4 and the fifth power switch installed in the outer shell 9. The component box 4 and the outer shell 9 are respectively installed in the middle of the outer front end of the frame 3 of the electric chain conveyor and the middle of the outer front end of the workbench. Workbench 1 is installed on the right side of the electric chain conveyor. The left end of its table is slightly lower (5 mm) than the right end of the electric chain conveyor, and the two are separated by a certain distance (1 cm). There is a water tank (not shown in the figure) on the ground between the right side of the electric chain conveyor and the left end of the table. The water tank outputs excess cooling water to the wastewater pool.
[0016] Figures 1-3As shown, the spraying mechanism includes a spray pipe 51 with a closed structure at both ends and a manual valve 52. Three spray nozzles 53 (with the same structure as agricultural sprayer nozzles) are installed at a distance from the bottom of the spray pipe 51. The lower end of the water outlet pipe of the manual valve 52 is welded to the rear end of the spray pipe 51 and is interconnected with the inside of the spray pipe 51. The water inlet pipe of the manual valve 52 is connected to the tap water pipe through a pipeline. The spray pipe 51 is welded to the upper middle part of the frame 3 of the electric chain conveyor with the spray nozzles 53 located on the lower side. The spray pipe 51 (with a distance between the lower end and the upper end of the chain plate) is located at the right end of the raw material bin 31. The pressure plate mechanism includes a cylinder 61, a hollow pressure plate 62, an inlet pipe 63 connected to the inside of the upper right side of the pressure plate 62, a sponge 64 inside the pressure plate, and multiple oil seepage holes 65 distributed at the lower end of the pressure plate. A fixing plate 66 is welded to the front left end of the worktable 1. The upper end of the cylinder barrel of the cylinder 61 is vertically fixedly installed at the lower end of the fixing plate 66. The inlet and outlet solenoid valves at the upper and lower ends of the cylinder barrel of the cylinder 61 and the exhaust pipe of the air compressor's air tank are connected in parallel through pipelines. The upper middle outer side of the pressure plate 62 is welded to the lower end of the piston rod of the cylinder. The oil supply mechanism includes an oil tank 71 (filled with oil), a manual valve A72, and a one-way air valve 73. An oil outlet pipe that communicates with the interior of the oil tank 71 is welded to the lower middle part of the oil tank 71. The oil outlet pipe is threaded to the upper inlet of the manual valve A72. A connecting pipe is installed at the lower outlet of the manual valve A72. The lower end of the connecting pipe is connected to the upper end of the inlet pipe 63 via a flexible hose 8 with a length allowance. The air inlet pipe of the one-way air valve 73 (which allows external air to enter the oil tank to prevent negative pressure from being generated inside) is installed on the upper outside of the oil tank 71 and communicates with the interior of the oil tank 71. The rear side of the oil tank 71 is welded to the front right end of the mounting plate of the workbench 1 (a refueling pipe 74 is installed in the upper middle part of the oil tank 71). The electric heating plate RT is a finished PTC electric heating plate with stainless steel armor (each with a power of 200W); the power module T1 is a finished AC 220V to DC 12V power module; the vibrating motor M2 has a power of 1.2KW; the electric chain conveyor M has a power of 4KW; the electric rotary conveyor valve M1 includes a metal volute, a star-shaped valve plate, and a heat-resistant motor reduction mechanism (a finished coaxial motor gear reducer with a power of 40W). The upper and lower ends of the volute are respectively welded with feed pipes and discharge pipes that communicate with its interior. The motor reduction mechanism is installed on the rear outer end of the volute, and its rotating shaft enters the volute through the shaft hole in the middle of the rear end of the volute. The middle part of the valve plate and the front end of the rotating shaft are welded together, and the valve plate is located inside the volute.
[0017] Figures 1-3As shown, the vibration motor M2 is connected in series via the two terminals of power switch S3. The power input terminals of multiple electric heating plates RT are connected in parallel via wires and then connected to the two terminals of power switch S2 (the guide connecting the power input terminals of the multiple electric heating plates extends outward through an opening in the middle of the upper left end of the heating chamber, and the opening is sealed with heat-resistant sealant). The two terminals of temperature switch W are connected in series. The power input terminal of the electric chain conveyor M is connected in series via power switch S1. The power input terminals 1 and 2 of power module T1 are connected to the two poles of AC 220V power supply via wires. The power output terminals 3 and 4 of power module T1 are connected to the power input terminals 1 and 2 of power switches S4 and S5 via wires. The power output terminals 3, 4, 5, and 6 of power switch S5 are connected to the power input terminals DC1 and DC2 of the upper and lower intake and exhaust solenoid valves of the cylinder via wires. The power output terminal of power switch S4 is connected to the power input terminal of the electric rotary conveyor valve M1 via wires.
[0018] Figures 1-3As shown, after turning on the main power switch S and power switch S2 (power module T1 is simultaneously energized), the operator (generally two operators are required to produce simultaneously to improve production efficiency) puts the pre-made material containing various raw materials into the raw material silo 31. When the temperature of the raw material silo 31 (which has a movable cover at the top for insulation) is below 80°C, the internal contacts of the temperature switch W (model KSD301, 80°C normally closed contact type snap-action temperature switch) close, thus energizing the electric heating plate RT to heat the pre-made material in the raw material silo (until it reaches a melting state). When the temperature of the raw material silo 31 is above 80°C, the internal contacts of the temperature switch W open, and the electric heating plate RT loses power and no longer heats the pre-made material in the raw material silo. Through the above, this new type of equipment can maintain the raw material silo 31 at a suitable temperature of 80°C during heating until all the raw materials are melted, at which point it can be put into production. After turning on power switch S3, the vibrating motor M2 and the electric chain conveyor are powered on and begin operation (the vibrating motor M2 vibrates to facilitate the subsequent flow of melted medication). AC power enters the power input terminal of power module T1, and pins 3 and 4 of power module T1 output a stable 12V DC power supply, which enters the power input terminals 1 and 2 of power switches S5 and S4. After turning on power switch S1, the electric chain conveyor M2 is powered on and its chain plate moves the transdermal patches placed on it by the subsequent workers from left to right. After the operator opens the manual valve 52, pressurized tap water enters the spray pipe 51 and then sprays out in a mist from the lower end of the three spray nozzles 53 (the size of the sprayed water mist can be adjusted by adjusting the opening and closing degree of the valve core of valve 52). After opening the manual valve A72, the oil in the oil tank enters the pressure plate 62 through the hose 8 with a length margin. The sponge 64 absorbs the oil (vegetable oil) and slowly seeps out from the multiple oil seepage holes 65 at the lower end of the pressure plate. The lower outer side of the pressure plate remains oily to prevent adhesion when pressing the medicine later (the amount of oil flowing out can be adjusted by adjusting the opening and closing degree of the valve core of valve A72).The worker, wearing heat-resistant gloves, lays a transdermal patch (rectangular non-woven fabric) flat at the lower end of the discharge pipe of the electric rotary delivery valve M1. With the other hand, they turn on the power switch S4. The electric rotary delivery valve M1 is then energized, and its motor reduction mechanism rotates the internal valve plate. This causes some of the melted medication to flow onto the transdermal patch. Because the flow rate of melted medication output from the electric rotary delivery valve M1 is relatively consistent, it is easier to control the amount of medication dispensed onto the transdermal patch. Once the sufficient amount of medication has flowed onto the transdermal patch, the valve is closed. Power switch S4 is activated, stopping the electric rotary conveyor valve M1 from outputting the molten drug. The operator then places the transdermal patch containing the drug onto the chain of the electric chain conveyor M. The chain of the electric chain conveyor M outputs the drug-laden transdermal patch to the spray mechanism. The spray nozzle 53 sprays a mist of cooling water to cool it. After cooling, the drug-laden transdermal patch, still at a certain residual temperature, enters the left end of the worktable via the right end of the electric chain conveyor (the drug-laden transdermal patch has inertia during movement, allowing it to enter the left end of the worktable). Through this process, the first operator can continuously spread the molten drug onto different transdermal patches in the most quantitative possible quantity, then cool it and output it to the left end of the worktable until the entire production process is completed.
[0019] Figures 1-3 As shown, after the transdermal patch containing the drug from the previous process enters the left end of the workbench, another worker places it flat on the upper part of the workbench and below the pressure plate 62. Then, the worker moves the handle of the power switch S5 to the left, connecting pins 1 and 2 and pins 3 and 4 of the power switch S5. This energizes the intake and exhaust solenoid valve DC1 at the upper end of the cylinder, opening the valve core. Compressed air from the air compressor enters the upper part of the cylinder through the intake port of solenoid valve DC1 (air at the lower end of the cylinder is discharged through the exhaust port of solenoid valve DC2). The piston in the cylinder moves downwards, and its piston rod moves downwards... The end of the cylinder drives the pressure plate 62 downwards to its stop point, flattening the medication on the transdermal patch. Then, the operator moves the handle of the power switch S5 to the right, connecting pins 1 and 2 and pins 5 and 6 respectively. This energizes the intake and exhaust solenoid valve DC2 at the lower end of the cylinder, opening its valve core. Compressed air from the air compressor enters the lower end of the cylinder through the intake port of solenoid valve DC2 (air at the upper end of the cylinder is exhausted through the exhaust port of solenoid valve DC1). The piston inside the cylinder moves upwards, and the lower end of its piston rod drives the pressure plate 62 upwards to its stop point, preparing to flatten the next transdermal patch containing medication. Through this process, the second operator can continuously flatten different transdermal patches containing medication and place them into the semi-finished product frame until all production is complete.
[0020] The above description illustrates the basic principles, main features, and advantages of this utility model. It will be apparent to those skilled in the art that this utility model is limited to the details of the exemplary embodiments described above, and that it can be implemented in other specific forms without departing from the spirit or basic characteristics of this utility model. Therefore, the embodiments should be considered exemplary and non-limiting in all respects. The scope of this utility model is defined by the appended claims rather than the foregoing description, and thus all variations falling within the meaning and scope of equivalents of the claims are intended to be included within this utility model.
[0021] Furthermore, it should be understood that although this specification describes the embodiments, the embodiments do not necessarily contain only one independent technical solution. This way of describing the specification is only for clarity. Those skilled in the art should regard the specification as a whole. The technical solutions in the embodiments can also be appropriately combined to form other embodiments that can be understood by those skilled in the art.
Claims
1. A novel transdermal patch production apparatus, comprising an electric chain conveyor, an electric heating mechanism, a spraying mechanism, a pressure plate mechanism, an oil supply mechanism, an air compressor, and a workbench; characterized in that, The rear frame of the electric chain conveyor is equipped with a fixed plate. The electric heating mechanism includes a raw material hopper, an electric rotary conveying valve, a vibrating motor, an electric heating plate, and a temperature switch. The lower end of the raw material hopper has a discharge port, and the inlet pipe of the electric rotary conveying valve is connected to the lower end of the discharge port. The outer end of the raw material hopper has a hollow heating chamber, and multiple electric heating plates are installed inside the heating chamber. The vibrating motor and temperature switch are fixedly installed on the outer end of the heating chamber. The rear outer end of the heating chamber is installed on the front end of the fixed plate. The spraying mechanism is installed on the frame of the electric chain conveyor, and the pressure plate mechanism and oil supply mechanism are respectively installed on both sides of the rear front end of the worktable. The worktable is installed on the side end of the electric chain conveyor.
2. The novel transdermal patch production device according to claim 1, characterized in that, The spraying mechanism includes a spray pipe and a valve. A spray nozzle is installed at the lower end of the spray pipe. The lower end of the valve's outlet pipe is installed on the spray pipe. The valve's inlet pipe and the tap water pipe are connected by a pipeline. The spray pipe is installed on a frame.
3. The novel transdermal patch production device according to claim 1, characterized in that, The pressure plate mechanism includes a cylinder and a pressure plate. The upper end of the pressure plate is equipped with a liquid inlet pipe, and the inside of the pressure plate is covered with a sponge. Multiple oil seepage holes are distributed at the lower end of the pressure plate. The cylinder barrel is installed on one side of the fixed plate of the worktable.
4. The novel transdermal patch production device according to claim 3, characterized in that, The oil supply mechanism includes an oil tank, valve A, and a one-way air valve. An oil outlet pipe is installed at the lower end of the oil tank and is connected to the upper end of valve A. A connecting pipe is installed at the lower outlet of valve A. The lower end of the connecting pipe is connected to the upper end of the inlet pipe via a flexible hose with sufficient length. The air inlet pipe of the one-way air valve is installed outside the upper end of the oil tank. The oil tank is installed on the other side of the fixed plate of the workbench.
5. The novel transdermal patch production device according to claim 1, characterized in that, The electric heating plate is a PTC electric heating plate.