A multi-functional phantom for pet / mr imaging quality detection

Abstract

The utility model provides a kind of PET-MR imaging quality detection multifunctional phantom, belong to PET / MR quality detection technical field, comprising: by inside to outside sequentially arranged uniformity detection module, PET / MR fusion degree test module, PET / MR resolution test module, PET / MR attenuation correction module;Uniformity detection module is by a cylindrical 68Ge-68Ga model body, 68Ge and epoxy resin and liquid polysulfide rubber are evenly mixed for simulating uniform radioactive division;PET / MR fusion degree test module includes hollow cylinder, when testing, inject Na source in hollow cylinder, carry out PET / MR scanning, obtain image fusion accuracy according to the obtained scanning image;It can be used for quality control to PET / MR imaging instrument, also can be used for finding the optimal scanning parameter of PET / MR imaging instrument, for teaching demonstration, for tracer screening etc., with wide application range.

Description

Technical Field

[0001] This utility model belongs to the field of PET / MR quality inspection technology, and specifically relates to a multifunctional phantom for PET / MR imaging quality inspection. Background Technology

[0002] With the rapid development of medical imaging technology, multimodal imaging technology has gradually become an important means of medical diagnosis. Among them, PET / MR (Positron Emission Tomography / Magnetic Resonance Imaging) technology combines the functional imaging of PET with the high-resolution anatomical imaging of MRI, enabling the simultaneous acquisition of functional, metabolic, and anatomical information of the body in a single examination, providing a more comprehensive and accurate basis for the early diagnosis and treatment of diseases.

[0003] However, the complexity of PET / MR imaging technology also presents challenges for image quality control. Currently, quality inspection of PET / MR imagers mainly relies on phantom testing. A phantom is a device used to simulate the characteristics of human tissue and to evaluate the performance parameters of imaging equipment. Existing phantoms suffer from limited functionality and low efficiency. To address these issues, this utility model patent provides a novel multifunctional phantom for PET / MR imaging quality inspection. It aims to overcome the shortcomings of existing technologies through innovative material selection, structural design, and functional integration, achieving more stable, reliable, and multifunctional quality inspection. Utility Model Content

[0004] This utility model addresses the problems of the prior art. The technical solution adopted in this application is: a multifunctional phantom for PET / MR imaging quality detection, comprising: a uniformity detection module, a PET / MR fusion test module, a PET / MR resolution test module, and a PET / MR attenuation correction module arranged sequentially from the inside to the outside;

[0005] The uniformity detection module consists of a cylindrical 68Ge-68Ga mold, in which 68Ge is uniformly mixed with epoxy resin and liquid polysulfide rubber to simulate uniform radioactivity.

[0006] The PET / MR fusion test module includes a hollow cylinder. During testing, a Na source is injected into the hollow cylinder, and a PET / MR scan is performed. The image fusion accuracy is obtained based on the obtained scan images.

[0007] The PET / MR resolution testing module consists of four identical sets of fine lines, each set of fine lines being composed of several sets of fine lines of different sizes;

[0008] The PET / MR attenuation correction module includes at least one hollow cylindrical insert, which is divided into two parts, one part located inside the phantom body and the other part located outside the phantom body.

[0009] Furthermore, the PET performance parameter test includes two of the four fine line groups, which are used to detect PET high contrast resolution and PET low contrast resolution, respectively; tracer is added to the fine lines in the high contrast resolution fine line group, and tracer is added to the periphery of the fine lines in the low contrast resolution fine line group; the MR performance parameter test includes the other two of the four fine line groups, which are used to detect MR high contrast resolution and MR low contrast resolution, respectively; the high contrast resolution module is used to test the ability of the measurement imaging system to resolve the smallest details of an object; the low contrast resolution module has fine lines of the same diameter in each group, but fine lines of different depths in each group.

[0010] Furthermore, the PET / MR resolution testing module consists of elongated ellipses of different sizes to distinguish the high and low contrast resolutions of PET and MR; multiple hollow cylinders of different diameters form a circumference, with the centers of the cross-sections of the hollow cylinders on the same circumferential layer; both the portion of the hollow cylinder insert located inside the phantom body and the portion located outside the phantom body are filled with tracer.

[0011] Furthermore, the PET / MR attenuation correction module can simulate nodules of different sizes and depths by using spheres of different sizes and thin tube lengths, and radioactive elements are added during detection to simulate in vivo scanning.

[0012] Compared with the prior art, the advantages and positive effects of this utility model are as follows:

[0013] This invention relates to a multifunctional phantom for PET / MR imaging quality testing, consisting of four concentric cylinders. From the inside out, these cylinders comprise a uniformity testing module, a PET / MR image fusion testing module, a PET performance parameter testing module, an MR performance parameter testing module, and an attenuation correction module. Each module is independent and does not affect the others, allowing for quality testing using only one or more modules. This phantom can be used for quality control of PET / MR imagers, as well as for finding optimal scanning parameters for PET / MR imagers, for teaching demonstrations, and for tracer screening, demonstrating its wide range of applications. Attached Figure Description

[0014] To more clearly illustrate the technical solutions in the embodiments of this utility model or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are some embodiments of this utility model. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0015] Figure 1 This is a stereoscopic view of a multifunctional phantom for PET / MR imaging quality inspection;

[0016] Figure 2 This is a top view of a multifunctional phantom for PET / MR imaging quality inspection;

[0017] Figure 3 This is a right view of a multifunctional phantom for PET / MR imaging quality inspection;

[0018] Figure 4 This is a three-dimensional view of the uniformity testing section of a multifunctional phantom for PET / MR imaging quality inspection;

[0019] Figure 5 This is a top view of the fusion testing section of a multifunctional phantom for PET / MR imaging quality inspection;

[0020] Figure 6 This is a top view of the resolution testing section of a multifunctional phantom for PET / MR imaging quality inspection;

[0021] Figure 7 This is a stereoscopic view of the attenuation correction section of a multifunctional phantom for PET / MR imaging quality inspection;

[0022] The diagram shows: 1. Uniformity detection module; 2. PET / MR fusion test module; 3. PET / MR resolution test module; 301. PET high contrast resolution test module; 302. MR low contrast resolution test model; 303. MR high contrast resolution test model; 304. PET low contrast resolution test model; 4. PET / MR attenuation correction module; 401. Simulated nodules of different sizes; 402. Thin tubes of different lengths; 5. Multifunctional phantom for PET / MR imaging quality detection. Detailed Implementation

[0023] To better understand the above-mentioned objectives, features, and advantages of this utility model, the present utility model will be further described below with reference to the accompanying drawings and embodiments. It should be noted that, unless otherwise specified, the embodiments and features described in these embodiments can be combined with each other.

[0024] Many specific details are set forth in the following description in order to provide a full understanding of the present invention. However, the present invention may also be implemented in other ways different from those described herein. Therefore, the present invention is not limited to the specific embodiments disclosed in the following specification.

[0025] Example 1, such as Figures 1-3 As shown, this application provides a multifunctional phantom for PET / MR imaging quality detection, comprising a uniformity detection module, a PET / MR fusion test module, a PET / MR resolution test module, and a PET / MR attenuation correction module arranged sequentially from the inside out.

[0026] The uniformity detection module 1 consists of a cylindrical 68Ge-68Ga mold, in which 68Ge is uniformly mixed with epoxy resin and liquid polysulfide rubber to simulate uniform radioactivity.

[0027] The PET / MR fusion test module 2 includes a hollow cylinder. During testing, a Na source is injected into the hollow cylinder, and a PET / MR scan is performed. The image fusion accuracy is obtained based on the obtained scan images. Specifically, advanced medical equipment that integrates PET and MR technologies, such as Siemens Biograph mMR, is used. It combines the advantages of positron emission tomography and magnetic resonance imaging. First, an MR scan is performed to obtain anatomical images, then a PET scan is performed to obtain functional metabolic images, and finally, the images are fused to generate a comprehensive image.

[0028] The PET / MR resolution testing module 3 consists of four identical sets of fine lines, each set composed of several sets of fine lines of different sizes. PET performance parameter testing includes two of the four sets of fine lines, used to detect PET high-contrast resolution and PET low-contrast resolution respectively. In the high-contrast resolution set, a tracer, such as FDG solution, is added to the fine lines; in the low-contrast resolution set, a tracer, such as FDG solution, is added to the periphery of the fine lines. MR performance parameter testing includes the other two of the four sets of fine lines, used to detect MR high-contrast resolution and MR low-contrast resolution respectively. The high-contrast resolution module is used to test the imaging system's ability to resolve the smallest details of an object when there is no severe noise; the test object is observed visually. In the low-contrast resolution module, each set of fine lines has the same diameter but different depths. The PET / MR resolution testing module 3 uses elongated ellipses of different sizes to distinguish the high and low contrast resolutions of PET and MR.

[0029] The PET / MR attenuation correction module 4 includes at least one hollow cylindrical insert, which is divided into two parts: one part is located inside the phantom body, and the other part is located outside the phantom body. The plurality of hollow cylinders of different diameters form a circumference, with the centers of the cross-sections of the hollow cylinders on the same circumferential layer; or the hollow cylinders are arranged in a row according to their diameter. Both the portion of the hollow cylindrical insert inside the phantom body and the portion outside the phantom body are filled with a tracer, such as FDG solution.

[0030] The PET / MR attenuation correction module 4 can simulate nodules of different sizes and depths by using spheres of different sizes and thin tubes of different lengths. Radioactive elements can be added during the detection to simulate in vivo scanning. The spheres are supported by thin tubes of different lengths and also serve as attenuation correction. Solid radioactive sources of different sizes, such as Na sources, can be added during the detection.

[0031] During testing, tracers were injected into both the portion of the hollow cylindrical insert inside the phantom and the portion outside the phantom, and PET / MR scans were performed. The accuracy of attenuation correction was determined based on the number of images of the portion of the hollow cylindrical insert inside the phantom and the portion outside the phantom obtained from the scans. The accuracy of attenuation correction can be determined using existing software systems.

[0032] Specifically, all the test components involved were 3D printed; the materials used for the radioactive sources in the tests included, but were not limited to, 18F-FDG solution.

[0033] The circular cylinder, representing the uniformity detection module 1, is located at the innermost part of the model. The outermost ring-shaped cylinder is the PET / MR fusion testing module 2. Above the outermost ring-shaped cylinder is the PET / MR resolution testing module 3. The outermost ring-shaped cylinder is the PET / MR attenuation correction module 4. The positional relationship is as shown in the reference. Figure 1 As shown.

[0034] The uniformity detection module contains a uniformly distributed cylinder of 68Ge, epoxy resin, and liquid polysulfide rubber to simulate a uniformly radioactive distribution, used for testing the uniformity of the equipment.

[0035] The fusion test model consists of cylinders of different diameters, which can be filled with a radioactive solution of 18F-FDG (fluorodeoxyglucose).

[0036] The embodiments described are not a single method of use. The uniformity test section, PET / MR fusion test section, resolution test section, and attenuation correction section can be combined and replaced according to specific test and correction requirements.

[0037] The above description is merely a preferred embodiment of the present utility model and is not intended to limit the present utility model in any other way. Any person skilled in the art may make changes or modifications to the above-disclosed technical content to create equivalent embodiments for application in other fields. However, any simple modifications, equivalent changes, and modifications made to the above embodiments based on the technical essence of the present utility model without departing from the technical solution of the present utility model shall still fall within the protection scope of the technical solution of the present utility model.

Claims

1. A multifunctional phantom for PET / MR imaging quality detection, characterized in that, include: The modules arranged from the inside out are: uniformity detection module, PET / MR fusion test module, PET / MR resolution test module, and PET / MR attenuation correction module. The uniformity detection module consists of a cylindrical 68Ge-68Ga mold, in which 68Ge is uniformly mixed with epoxy resin and liquid polysulfide rubber to simulate uniform radioactivity. The PET / MR fusion test module includes a hollow cylinder. During testing, a Na source is injected into the hollow cylinder, and a PET / MR scan is performed. The image fusion accuracy is obtained based on the obtained scan images. The PET / MR resolution testing module consists of four identical sets of fine lines, each set of fine lines being composed of several sets of fine lines of different sizes; The PET / MR attenuation correction module includes at least one hollow cylindrical insert, which is divided into two parts, one part located inside the phantom body and the other part located outside the phantom body.

2. The multifunctional phantom for PET / MR imaging quality detection according to claim 1, characterized in that, The PET performance parameter test includes two of the four fine line groups, which are used to detect PET high contrast resolution and PET low contrast resolution respectively; tracer is added to the fine line in the high contrast resolution fine line group, and tracer is added to the periphery of the fine line in the low contrast resolution fine line group. The MR performance parameter test includes two additional sets of the four fine line groups, which are used to detect MR high contrast resolution and MR low contrast resolution, respectively. The high-contrast resolution module is used to test the ability of a measurement imaging system to resolve the smallest details of an object. In the low-contrast resolution module, the diameter of the fine lines in each group is the same, but the depth of the fine lines in each group is different.

3. The multifunctional phantom for PET / MR imaging quality detection according to claim 1, characterized in that, The PET / MR resolution testing module consists of elongated ellipses of different sizes to distinguish the high and low contrast resolutions of PET and MR; multiple hollow cylinders of different diameters form a circumference, with the centers of the cross-sections of the hollow cylinders on the same circumferential layer; both the portion of the hollow cylinder insert inside the phantom body and the portion outside the phantom body are filled with tracer.

4. The multifunctional phantom for PET / MR imaging quality detection according to claim 1, characterized in that, The PET / MR attenuation correction module can simulate nodules of different sizes and depths by using spheres of different sizes and thin tube lengths. Radioactive elements are added during the detection to simulate in vivo scanning.

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