Exosome preparation-specific cryotube

Abstract

The utility model provides a kind of exosome preparation special cryopreservation tube, including cryopreservation tube body, the upper of the cryopreservation tube body is equipped with sealing cover cover body, annular outer fixed thread is opened in the outer surface of the sealing cover cover body, annular inner fixed thread is opened in the inner side wall of the cryopreservation tube body, it is related to cryopreservation tube technical field.This device can be convenient for the storage of exosome preparation by sealing cover cover body and cryopreservation tube body, and cooperate annular outer fixed thread and annular inner fixed thread are adapted, it can first layer be sealing cover cover body and cryopreservation tube body are sealed, it improves the storage effect of exosome preparation, fixed hole and fixed column are adapted, the resilience of extension spring, L type fixed rod and sliding hole are slidably connected, it can be convenient for second layer be sealing cover cover body and cryopreservation tube body are limit sealed, it can cooperate thermal expansion and contraction follow variation, it improves the sealing quality of sealing cover cover body and cryopreservation tube body.

Description

Technical Field

[0001] This utility model relates to the field of cryopreservation tube technology, specifically a cryopreservation tube for exosome preparations. Background Technology

[0002] Cryopreservation tubes, also known as microbial culture preservation tubes, magnetic bead preservation tubes, or magnetic bead cryopreservation tubes, are commonly used in microbiology laboratories for preserving microbial cultures. Common methods include the milk method, glycerol method, and slant method, among others. These methods vary in complexity and effectiveness.

[0003] Currently, cryovials are widely used in the storage of many experimental samples. However, cryovials used for storing exosome preparations have higher requirements. Existing cryovials are sealed by pressing the cap into the cryovial. This sealing method is prone to thermal expansion and contraction in low-temperature storage environments and can also lead to leakage due to poor sealing. Therefore, we provide a cryovial specifically designed for exosome preparations to solve this problem. Utility Model Content

[0004] The purpose of this invention is to provide a cryopreservation tube specifically for exosome preparations, so as to solve the problems mentioned in the background art and overcome its technical defects.

[0005] To solve the above-mentioned technical problems, the technical solution adopted by this utility model is: a cryopreservation tube for exosome preparations, including a cryopreservation tube body, a sealing cap body provided on the top of the cryopreservation tube body, an annular external fixing thread on the outer surface of the sealing cap body, an annular internal fixing thread on the inner side wall of the cryopreservation tube body, an auxiliary anti-leakage component connected to one side of the cryopreservation tube body, the auxiliary anti-leakage component including an annular slide, two bearing seats slidably connected to the inner wall of the annular slide, an L-shaped limiting rod connected to the inner ring of each bearing seat, a fixed hole on one side of each L-shaped limiting rod, two fixing brackets connected to one side of the sealing cap body, a sliding hole on one side of each fixing bracket and one side of the sealing cap body, an L-shaped fixing rod slidably connected to the inner wall of each set of sliding holes, a telescopic spring sleeved on the outer surface of each L-shaped fixing rod, and a fixing post connected to one side of each L-shaped fixing rod.

[0006] Preferably, one end of each of the telescopic springs is connected to one side of the fixing frame, and one end of each of the telescopic springs is connected to one side of the L-shaped fixed rod.

[0007] Preferably, each of the fixed holes is adapted to a fixed post, and the annular external fixing thread is adapted to the annular internal fixing thread.

[0008] Preferably, an observation window is fixedly embedded on the outer surface of the cryopreservation tube, and a scale is engraved on the outer surface of the observation window.

[0009] Preferably, each of the fixing frames has two reinforcing blocks connected to one side, and one side of each reinforcing block is connected to one side of the sealing cover.

[0010] Preferably, one side of the cryopreservation tube is connected to a shock-absorbing pad, and the outer surface of the shock-absorbing pad is coated with a waterproof layer.

[0011] Preferably, one end of each of the two L-shaped fixed rods is connected to a pull rod, and the outer surface of the pull rod is provided with anti-slip texture.

[0012] Preferably, one side of the sealing cap is connected to an annular sealing ring, which is adapted to the cryopreservation tube body.

[0013] Compared with the prior art, the beneficial effects of this utility model include:

[0014] 1. This device facilitates the storage of exosome preparations through the sealing cap and cryopreservation tube. It is compatible with the annular external fixing thread and the annular internal fixing thread, which can seal the first layer between the sealing cap and the cryopreservation tube, thereby improving the storage effect of exosome preparations.

[0015] 2. This device is slidably connected to the bearing seat via an annular slide, the outer surface of the L-shaped limiting rod is connected to the inner ring of the bearing seat, the fixed hole is adapted to the fixed column, the elastic force of the telescopic spring, and the L-shaped fixed rod is slidably connected to the sliding hole. This facilitates the second layer of sealing cap and cryogenic tube body to limit and seal, and it can follow the changes in thermal expansion and contraction, which improves the sealing quality of the sealing cap and cryogenic tube body. Attached Figure Description

[0016] The disclosure of this utility model is illustrated with reference to the accompanying drawings. It should be understood that the drawings are for illustrative purposes only and are not intended to limit the scope of protection of this utility model. In the drawings, the same reference numerals are used to refer to the same parts. Wherein:

[0017] Figure 1 This is a three-dimensional structural diagram of the cryopreservation tube body in this utility model;

[0018] Figure 2 This is a front sectional view of the cryopreservation tube body in this utility model;

[0019] Figure 3 This is a rear view of the cryopreservation tube body in this utility model;

[0020] Figure 4 This utility model Figure 3 Enlarged schematic diagram of the structure at point A;

[0021] The following are the labeling elements in the diagram: 1. Frozen tube body; 2. Sealing cap body; 3. Annular external fixing thread; 4. Annular internal fixing thread; 5. Auxiliary leak-proof component; 501. Annular slide; 502. Bearing seat; 503. L-shaped limit rod; 504. Fixed hole; 505. Fixing bracket; 506. Sliding hole; 507. L-shaped fixed rod; 508. Telescopic spring; 509. Fixing column; 6. Annular sealing ring; 7. Pull rod; 8. Anti-vibration pad; 9. Observation window; 10. Reinforcing block. Detailed Implementation

[0022] It is readily understood that, based on the technical solution of this utility model, those skilled in the art can propose various interchangeable structural methods and implementations without altering the essential spirit of this utility model. Therefore, the following detailed embodiments and accompanying drawings are merely illustrative descriptions of the technical solution of this utility model and should not be considered as the entirety of this utility model or as limitations or restrictions on the technical solution of this utility model.

[0023] According to one embodiment of the present invention, in conjunction with the appendix Figures 1-4 As shown.

[0024] A cryopreservation tube for exosome preparations includes a cryopreservation tube body 1, a sealing cap 2 at the top of the cryopreservation tube body 1, an annular external fixing thread 3 on the outer surface of the sealing cap 2, and an annular internal fixing thread 4 on the inner wall of the cryopreservation tube body 1. An auxiliary leak-proof component 5 is connected to one side of the cryopreservation tube body 1. The auxiliary leak-proof component 5 includes an annular slide 501, with two bearing seats 502 slidably connected to the inner wall of the annular slide 501. Each bearing seat 502 has an L-shaped limiting rod 503 connected to its inner ring. Each L-shaped limiting rod 503 has a fixed hole 504 on one side. Two fixing brackets 505 are connected to one side of the sealing cap 2. Each fixing bracket 505 and the sealing cap 2 have sliding holes 506 on one side. Each set of sliding holes 506 has an L-shaped fixing rod 507 slidably connected to the inner wall of the inner wall of each set of sliding holes 506. The outer surface of each L-shaped fixing rod 507... Each surface is fitted with a telescopic spring 508, and one side of each L-shaped fixed rod 507 is connected to a fixed post 509. Through the sealing cap 2 and the cryopreservation tube 1, exosome preparations can be conveniently stored. It is compatible with the annular external fixing thread 3 and the annular internal fixing thread 4, which can seal the first layer between the sealing cap 2 and the cryopreservation tube 1, thus improving the storage effect of exosome preparations. It is slidably connected to the bearing seat 502 through the annular slide 501. The outer surface of the L-shaped limiting rod 503 is connected to the inner ring of the bearing seat 502. The fixed hole 504 is compatible with the fixed post 509. The rebound force of the telescopic spring 508 and the sliding connection between the L-shaped fixed rod 507 and the sliding hole 506 can facilitate the second layer of sealing between the sealing cap 2 and the cryopreservation tube 1. It can follow the changes of thermal expansion and contraction, thus improving the sealing quality between the sealing cap 2 and the cryopreservation tube 1.

[0025] In this embodiment, one end of each telescopic spring 508 is connected to one side of the fixing frame 505, and one end of each telescopic spring 508 is connected to one side of the L-shaped fixed rod 507. The connection between the telescopic springs 508 and the fixing frame 505 and the L-shaped fixed rod 507 increases the installation quality of the fixed holes 504 and the fixed posts 509. Each fixed hole 504 is adapted to the fixed post 509, and the annular external fixing thread 3 is adapted to the annular internal fixing thread 4. This facilitates the installation of the sealing cap 2 and the cryopreservation tube body 1 for cryopreservation. An observation window 9 is fixedly embedded on the outer surface of the tube body 1. A scale is engraved on the outer surface of the observation window 9. Using the observation window 9 and the scale, the exosome preparation inside the cryopreservation tube body 1 can be easily observed, and the remaining amount of exosome preparation can be easily known. Two reinforcing blocks 10 are connected to one side of each fixing bracket 505. One side of each reinforcing block 10 is connected to one side of the sealing cap body 2. The reinforcing blocks 10 can increase the connection effect between the fixing bracket 505 and the sealing cap body 2, and prevent the breakage of the bracket.

[0026] In this embodiment, a shock-absorbing pad 8 is connected to one side of the cryopreservation tube body 1. The outer surface of the shock-absorbing pad 8 is coated with a waterproof layer. The shock-absorbing pad 8 can provide protective and slight shock absorption for the cryopreservation tube body 1. One end of the two L-shaped fixed rods 507 is connected to a pull rod 7. The outer surface of the pull rod 7 is provided with anti-slip texture. The pull rod 7 can be used to conveniently control the two L-shaped fixed rods 507 at the same time. An annular sealing ring 6 is connected to one side of the sealing cap 2. The annular sealing ring 6 is adapted to the cryopreservation tube body 1. The annular sealing ring 6 can increase the sealing effect of the sealing cap 2 and the cryopreservation tube body 1.

[0027] Working principle: First, the exosome preparation is poured into the cryopreservation tube body 1, and the sealing cap 2 is level with the cryopreservation tube body 1. Rotating the sealing cap 2 connects the annular external fixing thread 3 with the annular internal fixing thread 4, thus completing the first step of sealing the cryopreservation tube body 1 and the sealing cap 2. Then, pressing the pull rod 7 causes the two L-shaped fixed rods 507 and the two fixed posts 509 to descend, which in turn stretches the telescopic spring 508 and rotates the annular slide 50. 1. Simultaneously, it enables the bearing seat 502 to be horizontal with the fixed column 509. Then, the L-shaped limiting rod 503 is rotated. Immediately afterward, the rotation of the L-shaped limiting rod 503 makes the fixed hole 504 directly above the fixed column 509. Then, the pull rod 7 is released, and the rebound force of the telescopic spring 508 enables the L-shaped fixed rod 507 to drive the fixed column 509 to be inserted into the fixed hole 504. At the same time, it completes the second step of sealing the sealing cap 2 and the cryopreservation tube 1. The above is the complete usage process of this utility model.

[0028] The technical scope of this utility model is not limited to the content described above. Those skilled in the art can make various modifications and variations to the above embodiments without departing from the technical concept of this utility model, and all such modifications and variations should fall within the protection scope of this utility model.

Claims

1. A cryovial specifically for exosome preparations, characterized in that, The cryopreservation tube includes a cryopreservation tube body (1), a sealing cap (2) is provided on the top of the cryopreservation tube body (1), the outer surface of the sealing cap (2) is provided with an annular external fixing thread (3), the inner wall of the cryopreservation tube body (1) is provided with an annular internal fixing thread (4), and an auxiliary anti-leakage component (5) is connected to one side of the cryopreservation tube body (1). The auxiliary anti-leakage component (5) includes an annular slide (501), and the inner wall of the annular slide (501) is slidably connected to two bearing seats (502). Each bearing seat (502) has an L-shaped limiting rod connected to its inner ring. 503), each of the L-shaped limiting rods (503) has a fixed hole (504) on one side, and two fixing brackets (505) are connected to one side of the sealing cover body (2). Each fixing bracket (505) and the sealing cover body (2) have a sliding hole (506) on one side. The inner wall of each set of sliding holes (506) is slidably connected to an L-shaped fixed rod (507). Each L-shaped fixed rod (507) has a telescopic spring (508) on its outer surface. Each L-shaped fixed rod (507) has a fixing post (509) connected to one side of its side.

2. The cryopreservation tube for exosome preparations according to claim 1, characterized in that, One end of each of the telescopic springs (508) is connected to one side of the fixing frame (505), and one end of each of the telescopic springs (508) is connected to one side of the L-shaped fixed rod (507).

3. The cryovial for exosome preparations according to claim 1, characterized in that, Each of the fixed holes (504) is adapted to a fixed post (509), and the annular external fixing thread (3) is adapted to an annular internal fixing thread (4).

4. The cryopreservation tube for exosome preparations according to claim 1, characterized in that, The outer surface of the cryopreservation tube body (1) is fixedly inlaid with an observation window (9), and the outer surface of the observation window (9) is engraved with a scale.

5. The cryovial for exosome preparations according to claim 1, characterized in that, Each of the fixing brackets (505) has two reinforcing blocks (10) connected to one side, and one side of each of the reinforcing blocks (10) is connected to one side of the sealing cover (2).

6. The cryovial for exosome preparations according to claim 1, characterized in that, One side of the cryopreservation tube body (1) is connected to a shock-absorbing pad (8), and the outer surface of the shock-absorbing pad (8) is coated with a waterproof layer.

7. The cryovial for exosome preparations according to claim 1, characterized in that, One end of each of the two L-shaped fixed rods (507) is connected to a pull rod (7), and the outer surface of the pull rod (7) is provided with anti-slip texture.

8. The cryovial for exosome preparations according to claim 1, characterized in that, One side of the sealing cap (2) is connected to an annular sealing ring (6), which is compatible with the cryopreservation tube body (1).

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