Sample dissolution mixing device
By introducing a microcontroller and a pyroelectric sensor into the sample dissolution and mixing device, intelligent detection of dual-person operation is achieved, which solves the error and safety risks caused by single-person operation in traditional devices and improves the accuracy and safety of analysis results.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- 山西药科职业学院
- Filing Date
- 2025-06-09
- Publication Date
- 2026-07-07
AI Technical Summary
Traditional sample dissolution and mixing devices lack intelligent detection methods, which may lead to experimental errors and safety risks if operated by a single person. Especially in high-security analysis scenarios, it is difficult to deal with violations by a single person in a timely manner.
A sample dissolution and mixing device with a microcontroller and a pyroelectric sensor was designed. By monitoring the two-person operation procedures, intelligent detection is achieved using components such as flashing lights and audible and visual alarms to ensure the standardization of the two-person operation and to accelerate the mixing of drug samples and solvents under centrifugal force.
It enables intelligent detection of two-person operations, reducing the probability of experimental errors and safety accidents, and ensuring the accuracy of analysis results and the safety of operators.
Smart Images
Figure CN224471377U_ABST
Abstract
Description
Technical Field
[0001] This utility model relates to the field of drug analysis technology, and in particular to a sample dissolution and mixing device. Background Technology
[0002] In the field of pharmaceutical analysis, sample dissolution and mixing is a fundamental and crucial operation. The standardization and safety of this operation directly affect the accuracy of the analytical results and the safety of the experimental process.
[0003] Currently, traditional sample dissolution and mixing devices lack effective intelligent detection methods for ensuring compliance with two-person operating procedures. In high-safety analysis scenarios, single-person violations can pose numerous risks. On the one hand, single-person operation is prone to improper sample handling due to human error, leading to experimental errors that affect the reliability of drug analysis results and may cause deviations in drug quality assessment, misleading aspects of drug research and development, production, and quality control. On the other hand, the handling of certain special drug samples is inherently dangerous. If an emergency occurs during single-person operation, it is difficult to receive timely and effective response and assistance, greatly increasing the probability of safety accidents. This could not only endanger the lives of operators but also damage the experimental environment and surrounding facilities. Utility Model Content
[0004] This utility model relates to a sample dissolution and mixing device, which solves the problem that traditional sample dissolution and mixing devices lack effective intelligent detection methods for the execution of two-person operation procedures during operation.
[0005] This utility model provides a sample dissolving and mixing device, specifically comprising: a dissolving and mixing shell, wherein a circular groove structure driving rotating groove is formed on the left side of the top surface of the dissolving and mixing shell, and a dissolving and mixing barrel is rotatably mounted inside the driving rotating groove via a bearing, and a dissolving and mixing groove is formed on the top surface of the dissolving and mixing barrel; a mounting groove is formed on the bottom surface of the dissolving and mixing shell relative to the driving rotating groove, and a set of motors is fixedly mounted on the top surface of the mounting groove, the shaft end of the motors passing through the driving rotating groove and fixedly connected to the dissolving and mixing barrel; a mounting base is connected to the right side of the dissolving and mixing shell via a wire, and a mounting hole is formed on the top surface of the mounting base adjacent to the four edge corners, a monitoring shell is mounted on the top surface of the mounting base, a concealed groove is formed on the front surface of the monitoring shell, and a set of auxiliary pyroelectric sensors is fixedly mounted on the top surface of the concealed groove.
[0006] Furthermore, a microcontroller is installed inside the dissolution and mixing shell, and the microcontroller is electrically connected to the auxiliary pyroelectric sensor and the motor; a touch-sensitive operation panel, a power switch, and a flashing light are installed on the right side of the top surface of the dissolution and mixing shell, and the touch-sensitive operation panel, power switch, and flashing light are all electrically connected to the microcontroller; a set of main pyroelectric sensors are installed on the front surface of the dissolution and mixing shell, and the main pyroelectric sensors are electrically connected to the microcontroller; an audible and visual alarm is installed on the top surface of the monitoring shell, and the audible and visual alarm is electrically connected to the microcontroller.
[0007] Furthermore, the dissolution and mixing shell is also equipped with a timing module and a timer module electrically connected to the microcontroller. The timing module has a timing value of three minutes, and the timer module has a timer value of twenty seconds. When the timing module reaches its timing value, it sends a feedback signal to the microcontroller, which then controls the flashing light, the main pyroelectric sensor, the auxiliary pyroelectric sensor, and the timer module to start. When both the main pyroelectric sensor and the auxiliary pyroelectric sensor detect human infrared signals, the microcontroller controls the flashing light, the main pyroelectric sensor, the auxiliary pyroelectric sensor, and the timer module to turn off. When the timer module reaches its timer value, it sends a feedback signal to the microcontroller, which then controls the audible and visual alarm to start.
[0008] Furthermore, the top surface of the dissolving and mixing shell is provided with four limiting slots in a circular array adjacent to the drive rotating groove; a cover plate is provided above the dissolving and mixing shell, and four limiting posts are fixedly installed in a circular array on the bottom surface of the cover plate; when the four limiting posts are inserted into the four limiting slots, the cover plate completely covers and blocks the drive rotating groove; a transparent observation window is installed on both the top and bottom surfaces of the cover plate, and a cross-shaped stirring blade is fixedly installed on the bottom surface of the transparent observation window; when the four limiting posts are inserted into the four limiting slots, the cross-shaped stirring blade is located inside the dissolving and mixing tank; two handles are fixedly installed on the top surface of the cover plate in a symmetrical manner.
[0009] Furthermore, both the front and rear faces of the cover plate are provided with a locking slot in the form of an arc-shaped groove; the top face of the dissolving and mixing shell is provided with a T-shaped shaft groove adjacent to the front and rear sides of the drive rotating groove; a limiting rotating plate in the form of a circular plate is provided on both the front and rear sides of the top of the dissolving and mixing shell, and a T-shaped shaft is fixedly installed at the axial center of the bottom face of the limiting rotating plate, and the T-shaped shaft is rotatably connected to the T-shaped shaft groove; a disengagement cutting surface is provided on the outer circumference of the limiting rotating plate; when the disengagement cutting surface is not facing the cover plate, the limiting rotating plate is partially inserted into the locking slot; when the disengagement cutting surface is facing the cover plate, the limiting rotating plate disengages from the locking slot.
[0010] This invention provides a sample dissolution and mixing device, which has the following beneficial effects:
[0011] This invention achieves sealing of the top opening of the dissolving and mixing tank through a cover plate, and forms a mechanical limiting and fixing mechanism based on the limiting and locking slots, ensuring the sealing of the device during the mixing process and preventing leakage of drug samples or solvents. During dissolving and mixing, the dissolving and mixing tank is driven to rotate by a motor, and based on the cross-shaped stirring blades, the drug sample particles and solvent molecules are forced to pass through the gaps between the blades under centrifugal force, generating high-frequency collisions and friction. Centrifugal force is used to enhance the mass transfer process, accelerate the mixing and dissolution rate of drug samples and solvents, shorten sample preparation time, and improve analytical efficiency.
[0012] This invention enables intelligent detection and judgment of whether personnel strictly adhere to the two-person operation procedure during sample dissolution and mixing. Through positioning feedback from the timing module, a flashing light emits a visual warning, forcibly prompting personnel to check whether two-person operation is required. The main pyroelectric sensor senses the infrared signal of the human body at the operating station in real time, while the auxiliary pyroelectric sensor detects the intervention of personnel at the auxiliary station through a concealed slot. The timing module limits the detection time. If the two-person condition is not met simultaneously, an audible and visual alarm is automatically triggered, providing a dual alarm to indicate the violation. This invention can eliminate the risk of single-person operation from the source, meet the compliance requirements of high-safety analysis scenarios, and reduce the probability of experimental errors or safety accidents caused by human negligence. Attached Figure Description
[0013] To more clearly illustrate the technical solutions of the embodiments of this utility model, the accompanying drawings of the embodiments will be briefly described below.
[0014] The accompanying drawings described below are only related to some embodiments of the present invention and are not intended to limit the scope of the present invention.
[0015] In the attached diagram:
[0016] Figure 1 A schematic diagram of the top isometric structure of this utility model is shown;
[0017] Figure 2 A schematic diagram of the main structure of this utility model is shown;
[0018] Figure 3 This diagram shows a top isometric view of the structure of the present invention in its disassembled state.
[0019] Figure 4 This diagram shows the bottom isometric structure of the present invention in its disassembled state;
[0020] Figure 5 This utility model illustrates Figure 4 A magnified view of the structure at point A in the middle;
[0021] Figure 6 A system composition block diagram of this utility model is shown;
[0022] List of reference numerals
[0023] 1. Melting and mixing housing; 101. Touch control panel; 102. Power switch; 103. Flashing light; 104. Main pyroelectric sensor; 105. Mounting base; 106. Mounting holes; 107. Monitoring housing; 108. Audible and visual alarm; 109. Concealed slot; 1010. Secondary pyroelectric sensor; 1011. Drive slot; 1012. Bearing; 1013. Limit slot; 1014. T-slot; 1015. Mounting slot; 1016. Motor; 1017. Timing module; 1018. Timing module; 1019. Microcontroller;
[0024] 2. Cover plate; 201. Transparent observation window; 202. Handle; 203. Limiting post; 204. Cross-shaped stirring blades; 205. Locking slot;
[0025] 3. Limiting plate; 301. Disengagement from the cutting surface; 302. T-shaped shaft;
[0026] 4. Dissolving and mixing tank; 401. Dissolving and mixing vessel. Detailed Implementation
[0027] To make the objectives, technical solutions, and advantages of the embodiments of this utility model clearer, the technical solutions of the embodiments of this utility model will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some, not all, of the embodiments of this utility model. Based on the described embodiments of this utility model, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of this utility model.
[0028] Example: Please refer to Figures 1 to 6 :
[0029] This utility model discloses a sample dissolving and mixing device, comprising: a dissolving and mixing shell 1, a drive rotating groove 1011 with a circular groove structure is opened on the left side of the top surface of the dissolving and mixing shell 1, a dissolving and mixing tank 4 is rotatably mounted inside the drive rotating groove 1011 via a bearing 1012, and a dissolving and mixing channel 401 is opened on the top surface of the dissolving and mixing tank 4; a mounting groove 1015 is opened on the bottom surface of the dissolving and mixing shell 1 relative to the drive rotating groove 1011, and a set of motors 1016 is fixedly mounted on the top surface of the inner end of the mounting groove 1015, the rotating shaft end of the motors 1016 passes through the drive rotating groove 1011 and is fixedly connected to the dissolving and mixing tank 4; the right side of the dissolving and mixing shell 1 is open. A mounting base 105 is connected via a wire. Mounting holes 106 are provided at the four corners of the top surface of the mounting base 105. A monitoring housing 107 is mounted on the top surface of the mounting base 105. A concealed groove 109 is provided on the front surface of the monitoring housing 107. A set of auxiliary pyroelectric sensors 1010 is fixedly mounted on the top surface of the inner end of the concealed groove 109. A microcontroller 1019 is installed inside the dissolving and mixing housing 1. The microcontroller 1019 is electrically connected to the auxiliary pyroelectric sensors 1010 and the motor 1016. A touch-sensitive operation panel 101, a power switch 102, and a flashing light 103 are installed on the right side of the top surface of the dissolving and mixing housing 1. Board 101, power switch 102, and flashing light 103 are all electrically connected to microcontroller 1019; a set of main pyroelectric sensors 104 are installed on the front end of the dissolving and mixing shell 1, and the main pyroelectric sensors 104 are electrically connected to microcontroller 1019; an audible and visual alarm 108 is installed on the top end of the monitoring shell 107, and the audible and visual alarm 108 is electrically connected to microcontroller 1019; the dissolving and mixing shell 1 also contains a timing module 1017 and a timer module 1018 electrically connected to microcontroller 1019, the timing value of the timing module 1017 is three minutes, and the timer value of the timer module 1018 is twenty seconds; when the timing value of the timing module 1017 is reached... The timing module 1017 sends a feedback signal to the microcontroller 1019, which then controls the flashing light 103, the main pyroelectric sensor 104, the auxiliary pyroelectric sensor 1010, and the timing module 1018 to start. When both the main pyroelectric sensor 104 and the auxiliary pyroelectric sensor 1010 detect the human infrared signal, the microcontroller 1019 controls the flashing light 103, the main pyroelectric sensor 104, the auxiliary pyroelectric sensor 1010, and the timing module 1018 to turn off. When the timing value of the timing module 1018 is reached, the timing module 1018 sends a feedback signal to the microcontroller 1019, which then controls the audible and visual alarm 108 to start.
[0030] In this embodiment, the top surface of the dissolving and mixing shell 1 is adjacent to the drive rotating groove 1011 and has four limiting slots 1013 arranged in a ring array. A cover plate 2 is provided above the dissolving and mixing shell 1, and four limiting posts 203 are fixedly installed in a ring array on the bottom surface of the cover plate 2. When the four limiting posts 203 are engaged with the four limiting slots 1013, the cover plate 2 completely covers and blocks the drive rotating groove 1011. A transparent observation window 201 is installed on both the top and bottom surfaces of the cover plate 2, and a cross-shaped stirring blade 204 is fixedly installed on the bottom surface of the transparent observation window 201. When the four limiting posts 203 are engaged with the four limiting slots 1013, the cross-shaped stirring blade 204 is located inside the dissolving and mixing tank 401. The top surface of the cover plate 2 is symmetrically fixed with four limiting posts 1013. Two handles 202 are installed; a locking slot 205 with an arc-shaped groove structure is opened on the front and rear faces of the cover plate 2; a T-shaped shaft groove 1014 is opened on the top face of the dissolving and mixing shell 1 adjacent to the front and rear sides of the drive rotating groove 1011; a limiting rotating plate 3 with a circular plate structure is provided on the front and rear sides of the dissolving and mixing shell 1, and a T-shaped shaft 302 is fixedly installed on the axial part of the bottom face of the limiting rotating plate 3. The T-shaped shaft 302 is rotatably connected to the T-shaped shaft groove 1014; a disengagement cutting surface 301 is opened on the outer peripheral surface of the limiting rotating plate 3; when the disengagement cutting surface 301 is not facing the cover plate 2, the limiting rotating plate 3 is partially inserted into the locking slot 205; when the disengagement cutting surface 301 is facing the cover plate 2, the limiting rotating plate 3 is disengaged from the locking slot 205.
[0031] The working principle of this embodiment:
[0032] The drug sample to be analyzed and the solvent used to assist dissolution are added into the dissolution mixing tank 401. Then, the operator can grasp the handle 202 to move the cover plate 2 above the dissolution mixing shell 1, so that the four limiting pins 203 are aligned with the four limiting slots 1013 and inserted, so that the cover plate 2 blocks and seals the top opening of the dissolution mixing tank 401. Then, the operator can rotate the limiting plate 3 along the T-shaped shaft groove 1014 through the rotational cooperation between the T-shaped shaft 302 and the T-shaped shaft groove 1014, so that the detachment cut surface 301 of the limiting plate 3 is no longer facing the cover plate 2. At this time, part of the structure of the limiting plate 3 is rotated and inserted into the locking slot 205, thereby limiting and fixing the position of the cover plate 2.
[0033] During dissolution and mixing, the operator sends a command to the microcontroller 1019 via the touch panel 101. The microcontroller 1019 controls the motor 1016 to start, and the shaft of the motor 1016 synchronously drives the dissolution and mixing tank 4 to rotate. Since the cross-shaped stirring blade 204 is located inside the dissolution and mixing tank 401, the drug sample and solvent in the dissolution and mixing tank 401 will come into contact with the cross-shaped stirring blade 204. Under the action of centrifugal force, the drug sample particles and solvent molecules in the dissolution and mixing tank 401 are forced to pass through the gap between the blades of the cross-shaped stirring blade 204, and collide and rub against each other to achieve mixing, thereby accelerating the dissolution and mixing efficiency.
[0034] To ensure operational safety during drug sample analysis, strict adherence to two-person operating procedures is required. The specific steps are as follows:
[0035] The mounting base 105 is located in a region away from the melting and mixing shell 1, and its position is fixed by fasteners passing through the mounting holes 106.
[0036] When the timer module 1017 reaches its set time (three minutes), it sends a feedback signal to the microcontroller 1019. The microcontroller 1019 then activates the flashing light 103, the main pyroelectric sensor 104, the auxiliary pyroelectric sensor 1010, and the timing module 1018. The flashing light 103 serves as a reminder to the operator, while the main pyroelectric sensor 104 detects the infrared signal of the operator currently responsible for the melting and mixing process. If the operation is strictly performed by two people as per regulations, the other operator can approach the mounting base 105 and insert their hand into the concealed slot 109, allowing the auxiliary pyroelectric sensor 1010 to detect the signal. When both the main pyroelectric sensor 104 and the auxiliary pyroelectric sensor 1010 detect the human infrared signal, the microcontroller 1019 controls the flashing light 103, the main pyroelectric sensor 104, the auxiliary pyroelectric sensor 1010, and the timing module 1018 to turn off. However, if the operation is not performed by two people as scheduled, both the main pyroelectric sensor 104 and the auxiliary pyroelectric sensor 1010 cannot detect the human infrared signal. When the timing module 1018 reaches its timing value (twenty seconds), the timing module 1018 sends a feedback signal to the microcontroller 1019, which then controls the audible and visual alarm 108 to activate, providing a dual audible and visual alarm to alert the user to the violation.
Claims
1. A sample dissolving and mixing device, characterized in that, include: A dissolving and mixing shell (1) has a circular drive groove (1011) on the left side of its top surface. A dissolving and mixing tank (4) is rotatably mounted inside the drive groove (1011) via a bearing (1012). A dissolving and mixing trough (401) is formed on the top surface of the dissolving and mixing tank (4). A mounting groove (1015) is formed on the bottom surface of the dissolving and mixing shell (1) relative to the drive groove (1011). A set of motors (1016) is fixedly mounted on the top surface of the inner end of the mounting groove (1015). The shaft end of 6) passes through the drive groove (1011) and is fixedly connected to the dissolving and mixing tank (4); a mounting base (105) is connected to the right side of the dissolving and mixing shell (1) by a wire. A mounting hole (106) is opened at the corner of the four edges adjacent to the top surface of the mounting base (105). A monitoring shell (107) is installed on the top surface of the mounting base (105). A concealed groove (109) is opened on the front surface of the monitoring shell (107). A set of auxiliary pyroelectric sensors (1010) is fixedly installed on the top surface of the inner end of the concealed groove (109).
2. The sample dissolving and mixing device according to claim 1, characterized in that, The dissolution and mixing shell (1) is equipped with a microcontroller (1019), which is electrically connected to the auxiliary pyroelectric sensor (1010) and the motor (1016). A touch-sensitive operation panel (101), a power switch (102) and a flashing light (103) are installed on the right side of the top surface of the dissolution and mixing shell (1). The touch-sensitive operation panel (101), the power switch (102) and the flashing light (103) are all electrically connected to the microcontroller (1019). A set of main pyroelectric sensors (104) is installed on the front surface of the dissolution and mixing shell (1). The main pyroelectric sensors (104) are electrically connected to the microcontroller (1019). An audible and visual alarm (108) is installed on the top surface of the monitoring shell (107). The audible and visual alarm (108) is electrically connected to the microcontroller (1019).
3. The sample dissolving and mixing device according to claim 2, characterized in that, The melting and mixing shell (1) is further equipped with a timing module (1017) and a timing module (1018) electrically connected to the microcontroller (1019). The timing module (1017) has a timing value of three minutes, and the timing module (1018) has a timing value of twenty seconds. When the timing value of the timing module (1017) is reached, the timing module (1017) sends a feedback signal to the microcontroller (1019), and the microcontroller (1019) controls the flashing light (103), the main pyroelectric sensor (104), the auxiliary pyroelectric sensor (1010), and... The timing module (1018) is activated; when both the main pyroelectric sensor (104) and the auxiliary pyroelectric sensor (1010) detect the human infrared signal, the microcontroller (1019) controls the flashing light (103), the main pyroelectric sensor (104), the auxiliary pyroelectric sensor (1010) and the timing module (1018) to turn off; when the timing value of the timing module (1018) is reached, the timing module (1018) sends a feedback signal to the microcontroller (1019), and the microcontroller (1019) controls the sound and light alarm (108) to start.
4. The sample dissolution and mixing device according to claim 3, characterized in that, The top surface of the melting and mixing shell (1) adjacent to the drive rotating groove (1011) has four limiting slots (1013) arranged in a ring array; a cover plate (2) is provided above the melting and mixing shell (1), and four limiting pins (203) are fixedly installed in a ring array on the bottom surface of the cover plate (2); when the four limiting pins (203) are inserted into the four limiting slots (1013), the cover plate (2) completely covers and blocks the drive rotating groove (1011). 11) Location; A transparent observation window (201) is installed on the top and bottom surfaces of the cover plate (2), and a cross-shaped stirring blade (204) is fixedly installed on the bottom surface of the transparent observation window (201); When the four limiting posts (203) are inserted into the four limiting slots (1013), the cross-shaped stirring blade (204) is located inside the dissolving and mixing tank (401); The top surface of the cover plate (2) is symmetrical and has two handles (202) fixedly installed.
5. The sample dissolution and mixing device according to claim 4, characterized in that, The front and rear faces of the cover plate (2) are each provided with a locking slot (205) with an arc-shaped groove structure; the top face of the dissolving and mixing shell (1) is provided with a T-shaped shaft groove (1014) on the front and rear sides adjacent to the drive rotating groove (1011); the front and rear sides of the dissolving and mixing shell (1) are each provided with a limiting rotating plate (3) with a circular plate structure, and a T-shaped shaft (302) is fixedly installed on the axial part of the bottom face of the limiting rotating plate (3), and the T-shaped shaft (302) is rotatably connected to the T-shaped shaft groove (1014); the outer circumferential surface of the limiting rotating plate (3) is provided with a disengagement cutting surface (301); when the disengagement cutting surface (301) is not facing the cover plate (2), the limiting rotating plate (3) is partially inserted into the locking slot (205); when the disengagement cutting surface (301) is facing the cover plate (2), the limiting rotating plate (3) is disengaged from the locking slot (205).