A brucellosis rose bengal plate agglutination test plate
By designing a Brucella agglutination test plate made of highly transparent PMMA material, the problems of opaque reaction paper and operational errors were solved, thereby improving the clarity and safety of the test results. It is suitable for both manual and instrumental testing.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- NANJING YINGJIE BIOTECHNOLOGY CO LTD
- Filing Date
- 2024-11-05
- Publication Date
- 2026-07-07
AI Technical Summary
In the existing Brucella agglutination test using red agar plates, the reaction paper is not transparent enough, the experimental results are unclear, the liquid is prone to exceed the range, posing a safety risk, and the operation error is large.
A red brucellosis plate agglutination test was designed using highly transparent PMMA material. The test groove has an angle of 23.5° and 113.5° and is reinforced with ribs. It is suitable for testing multiple samples and ensures uniform liquid distribution and full contact of reagents.
It improves the clarity and security of test results, reduces operational errors, is suitable for both manual and instrumental testing, and enhances testing efficiency and sensitivity.
Smart Images

Figure CN224471687U_ABST
Abstract
Description
Technical Field
[0001] This utility model relates to the field of test plate technology, specifically a Brucella rhubarb agglutination test plate. Background Technology
[0002] Brucellosis is a zoonotic infectious disease caused by infection with Brucella bacteria. The Bengal plate agglutination test, also known as the Bengal plate agglutination test, uses an acidic (pH 3.6-3.9) colored antigen. This antigen inhibits the agglutination activity of IgM antibodies in the serum, and since the tested antibody is IgG, the specificity of the reaction is improved. The test is valid when no agglutination occurs in standard negative serum and agglutination occurs in standard positive serum. A positive result (+) is indicated by visible agglutination, while a negative result (-) is indicated by the absence of agglutination and a uniformly pink color in the reaction mixture.
[0003] Currently, the Rose Bengal plate agglutination test for brucellosis remains the most frequently used and primary detection method for brucellosis diagnosis in my country. It is a legally mandated detection method in my country and is also the designated test for brucellosis detection in cattle, sheep, and pigs in international trade. This method has advantages such as low reagent cost, simple operation, speed, and high detection rate, and is widely used in large-scale brucellosis screening, introduction of new breeds, and evaluation of vaccine immunization efficacy. Because this method does not require special testing equipment, it is more suitable for grassroots laboratories and field trials. After simple training, farmers can also perform the test themselves. It provides a powerful detection tool for the prevention and eradication of brucellosis. The Rose Bengal plate agglutination test procedure begins with collection and isolation using standard methods.
[0004] Disposable brucellosis agglutination reaction paper is used for the rose benzene plate agglutination test, replacing traditional glass plates or slides, ensuring the safety of laboratory personnel, and offering convenience, speed, and good results. However, the reaction paper is not transparent enough, which may result in unclear experimental results and interfere with manual interpretation. Furthermore, the reaction paper lacks fixed boundaries, and liquid may exceed the prescribed mixing and spreading area, affecting the experimental results. Errors may occur when adding serum and antigen, and consistent mixing cannot be guaranteed. Additionally, brucellosis detection experiments carry certain safety risks; Brucella can be transmitted through broken skin and mucous membranes, the digestive tract, and the respiratory tract, and manual handling carries the risk of infection.
[0005] Therefore, the applicant proposes a brucellosis ... Utility Model Content
[0006] The purpose of this invention is to provide a Brassica juncea agglutination test plate for Brucella infection, which can replace traditional glass slides for Brassica juncea agglutination tests. It is safe, efficient, and easy to use, and can be used only once.
[0007] To achieve the above objectives, the present invention proposes the following technical solution: a Brucella agglutination plate, comprising a plate body (1), wherein a detection groove (2) is provided on the plate body (1), the detection groove (2) is used to hold the detection liquid, the detection groove (2) comprises a bottom surface (201), an inclined surface (202) and an arc surface (203), the included angle between the inclined surface (202) and the vertical surface is 23.5°, the included angle between the bottom surface (201) and the inclined surface (202) is 113.5°, and a groove (3) is provided at the bottom of the plate body (1).
[0008] Furthermore, in this invention, the number of detection slots (2) is twenty-four.
[0009] Furthermore, in this utility model, the material of the plate (1) is high-transparency PMMA material.
[0010] Furthermore, in this invention, reinforcing ribs (4) are fixedly connected between the detection grooves (2).
[0011] Furthermore, in this utility model, the plate (1) is 3mm thick, 114mm long, and 74mm wide.
[0012] Beneficial effects: The technical solution of this application has the following technical effects:
[0013] This invention can replace traditional glass slides in the Rosacea plate agglutination test. It is disposable, safe, efficient, convenient, and highly transparent. The liquid spreads evenly within the well without external force, meeting national standards and contributing to clear test results with distinct positive and negative results. It is suitable for both manual testing and use with compatible instruments. The raw material, PMMA, possesses sufficient stability and corrosion resistance, ensuring that the reagents and samples are not affected by material properties, thus preventing the results from being compromised.
[0014] It should be understood that all combinations of the foregoing concepts and the additional concepts described in more detail below can be considered as part of the utility model subject matter of this disclosure, provided that such concepts do not contradict each other.
[0015] The foregoing and other aspects, embodiments, and features of the present invention will be more fully understood from the following description in conjunction with the accompanying drawings. Other additional aspects of the present invention, such as features and / or beneficial effects of exemplary embodiments, will become apparent from the following description or may be learned through practice of specific embodiments according to the teachings of the present invention. Attached Figure Description
[0016] The accompanying drawings are not intended to be drawn to scale. In the drawings, each identical or nearly identical component shown in the various figures may be denoted by the same reference numeral. For clarity, not every component is labeled in each figure. Embodiments of various aspects of the present invention will now be described by way of example and with reference to the accompanying drawings, wherein:
[0017] Figure 1 This is a schematic diagram of the structure of this utility model.
[0018] Figure 2 This is a side view of the present invention.
[0019] Figure 3 This is a partial structural cross-sectional view of the present invention.
[0020] The meanings of the labels in the figures are as follows: 1. Plate; 2. Plate; 3. Groove; 4. Reinforcing rib; 201. Bottom surface; 202. Inclined surface; 203. Curved surface. Detailed Implementation
[0021] To better understand the technical content of this utility model, specific embodiments are described below in conjunction with the accompanying drawings. Various aspects of this utility model are described in this disclosure with reference to the accompanying drawings, which illustrate numerous illustrative embodiments. The embodiments of this disclosure are not necessarily defined to include all aspects of this utility model. It should be understood that the various concepts and embodiments described above, as well as those described in more detail below, can be implemented in any of many ways, because the concepts and embodiments disclosed in this utility model are not limited to any particular implementation. Furthermore, some aspects of this utility model can be used alone or in any suitable combination with other aspects disclosed in this utility model.
[0022] Example 1
[0023] like Figure 1-3 As shown, a brucellosis red arsenic agglutination plate test includes a plate body 1 with a test groove 2 for holding the test solution. The test groove 2 includes a bottom surface 201, an inclined surface 202, and an arc surface 203. The angle between the inclined surface 202 and the vertical plane is 23.5°, and the angle between the bottom surface 201 and the inclined surface 202 is 113.5°. The angle design of the inclined surface and the bottom surface—the angle between the inclined surface 202 and the vertical plane is 23.5°, and the angle between the bottom surface 201 and the inclined surface 202 is 113.5°—facilitates the distribution and mixing of the liquid in the groove, ensuring sufficient contact between the reagent and the sample, and improving the sensitivity and accuracy of the reaction. The presence of the arc surface reduces the influence of surface tension of the liquid in the groove, ensuring a more uniform distribution of the reagent, thereby improving the reliability of the experimental results. A groove 3 is provided at the bottom of the plate body 1.
[0024] Example 2
[0025] like Figure 1-3 As shown, a brucellosis red agar plate agglutination test plate, based on Example 1, has twenty-four test slots 2. This number allows for the simultaneous testing of multiple groups of samples, improving work efficiency and making it suitable for large-scale screening. The plate body 1 is made of highly transparent PMMA material, which not only has good transparency for easy observation of reaction results but also excellent chemical resistance and mechanical strength, ensuring the safety and reliability of the experiment. Reinforcing ribs 4 are fixedly connected between the test slots 2. This design enhances the structural stability of the plate body, prevents deformation due to pressure or temperature changes during use, and improves the repeatability of the experiment.
[0026] The plate 1 is 3mm thick, 114mm long, and 74mm wide. The 3mm thickness and 114mm x 74mm dimensions make the plate both sturdy and easy to handle, suitable for handheld use and placement on a lab bench, facilitating experimental operations. The design goal of this Brucella rhubarb agglutination plate in this embodiment is to improve the sensitivity, efficiency, and reliability of detection, adapting to large-scale testing needs while ensuring safety and convenience during the experimental process. These design features work together to enhance the performance of this test plate in practical applications.
[0027] All standard parts used in this application can be purchased from the market, and can be customized according to the description and drawings. The specific connection methods of each part adopt conventional methods such as bolts, rivets, and welding that are mature in the prior art. The machinery, parts and equipment adopt conventional models in the prior art. The control method is automatic control through a controller. The control circuit of the controller can be implemented by simple programming by those skilled in the art and is common knowledge in the field. Since this application is mainly used to protect mechanical devices, the control method and circuit connection will not be explained in detail in this application.
[0028] Although the present invention has been disclosed above with reference to preferred embodiments, it is not intended to limit the present invention. Those skilled in the art to which this invention pertains can make various modifications and refinements without departing from the spirit and scope of the present invention. Therefore, the scope of protection of this invention shall be determined by the claims.
Claims
1. A red rubella agglutination plate for brucellosis, characterized in that: The plate includes a plate (1), on which a detection groove (2) is provided. The detection groove (2) is used to hold the detection liquid. The detection groove (2) includes a bottom surface (201), an inclined surface (202) and an arc surface (203). The angle between the inclined surface (202) and the vertical plane is 23.5°, and the angle between the bottom surface (201) and the inclined surface (202) is 113.5°. A groove (3) is provided at the bottom of the plate (1).
2. The Brucella agglutination test plate according to claim 1, characterized in that: The number of detection slots (2) is twenty-four.
3. The brucellosis red agar plate agglutination test plate according to claim 1, characterized in that: The plate (1) is made of highly transparent PMMA material.
4. The brucellosis red agar plate agglutination test plate according to claim 1, characterized in that: The detection grooves (2) are fixedly connected by reinforcing ribs (4).
5. The brucellosis red agar plate agglutination test plate according to claim 1, characterized in that: The plate (1) is 3mm thick, 114mm long, and 74mm wide.