A concentrated treatment device for vanadium oxides

Abstract

The utility model discloses a kind of concentrated treatment devices of V-type oxide, including concentration tank, drive mechanism and agitating mechanism are equipped in concentration tank, agitating mechanism includes middle shaft, the outside of middle shaft is equipped with several stirring rods, the outside of middle shaft and stirring rod is equipped with same stirring blade, drive mechanism drives stirring rod and stirring blade to rotate back and forth by middle shaft, stirring rod and stirring blade stir material by self-motion. The utility model can break liquid surface tension by driving stirring rod and stirring blade to rotate back and forth in concentration tank, so that material produces more chaotic flow, and then ensure that heat is evenly distributed in the concentration process, to facilitate to speed up solvent evaporation, guarantee the efficiency and uniformity of concentration;Simultaneously, by the continuous stirring material to maintain material flow, also can reduce the residue of product on bottle wall, to prevent product loss in this way.

Description

Technical Field

[0001] This utility model relates to the field of Warwick oxide concentration technology, and in particular to a Warwick oxide concentration treatment device. Background Technology

[0002] Warwick oxide, chemical name: 16,17α-epoxy-4-pregnen-3,20-dione, has a cyclopentane-perhydrophenanthrene core and is a typical steroid compound. It is an important intermediate in the synthesis of various corticosteroid drugs.

[0003] Warburg oxide is a product obtained by epoxidizing dienolone acetate (diene) with hydrogen peroxide, concentrating, performing the Warburg oxidation reaction, destroying aluminum isopropoxide with sodium hydroxide, followed by steam distillation, centrifugation to obtain the crude product, and purification with ethanol to obtain the final product. In the above material concentration process, stirring is an indispensable auxiliary method. This can improve heat transfer, mass transfer, and uniformity, thus increasing efficiency and protecting the structural integrity of the product.

[0004] A search revealed that Chinese utility model patent CN222195916U discloses a Wollstone oxide vacuum concentration device, including a base, with a concentrator housing fixedly connected to the top of the base, and a pressure gauge fixedly connected to the surface of the concentrator housing. This application uses an electric stirring rod to agitate the material during vacuum concentration to ensure uniform oxide concentration. However, the device's method of agitation is relatively simple, resulting in limited agitation effect and making it difficult to guarantee the concentration efficiency and uniformity of the material. Utility Model Content

[0005] In view of the above-mentioned prior art, the present invention provides a concentration treatment device for Warwick oxides, and the main technical problem to be solved is how to ensure the efficiency and uniformity of material concentration.

[0006] To achieve the above objectives, the technical solution of this utility model embodiment is implemented as follows:

[0007] A concentration treatment device for Warburg oxide includes a concentration tank, which is equipped with a drive mechanism and a stirring mechanism. The stirring mechanism includes a central shaft, a plurality of stirring rods are provided on the outer side of the central shaft, and the same stirring blade is provided on the outer side of the central shaft and the stirring rods. The drive mechanism drives the stirring rods and stirring blades to rotate back and forth through the central shaft, and the stirring rods and stirring blades stir the material by their own movement.

[0008] Furthermore, the top of the concentration tank is equipped with a lid, and a circular opening is provided at the center of the top of the lid. The central shaft is rotatably connected to the lid at the circular through hole, and a cover is fixedly connected to the top of the lid outside the central shaft.

[0009] Furthermore, two sliding rods are fixedly connected at one end between the inner sides of the cover. The two sliding rods are respectively fitted with a collar and a sliding sleeve, and a fixing frame is fixedly connected between the collar and the sliding sleeve.

[0010] Furthermore, the sliding sleeve is located on the side near the central shaft, and the top of the central shaft is connected to a second gear via a key. A second rack is fixedly connected to the side of the sliding sleeve away from the fixed frame, and the second rack meshes with the second gear.

[0011] Furthermore, a circular through hole is provided at the top of the cover inside the fixed frame, and a housing is fixedly connected to the top of the cover outside the circular through hole. The drive mechanism includes a motor installed in the housing.

[0012] Furthermore, the bottom end of the motor's output shaft extends into the interior of the housing through a circular through hole, and the bottom end of the motor's output shaft is connected to a first gear via a key. The first gear is an incomplete gear.

[0013] Furthermore, first racks are fixedly connected to the inner walls on both sides of the fixed frame, and the first gear meshes with both first racks.

[0014] Furthermore, a base is provided below the concentration tank, and several pillars are fixedly connected at equal intervals on the outer side between the concentration tank and the base. The bottom of the concentration tank is hemispherical, and the stirring blade is U-shaped to match the concentration tank.

[0015] Furthermore, a scraper is fixedly connected to the outer side of the stirring blade. The scraper is made of rubber and is a triangular prism shape that is narrow on the outside and wide on the inside.

[0016] The beneficial effects of this utility model are as follows:

[0017] 1. This application breaks the surface tension of the liquid by driving the stirring rod and stirring blade to rotate back and forth in the concentration tank, which makes the material generate a more chaotic liquid flow, thereby ensuring the uniform distribution of heat during the concentration process, so as to accelerate solvent evaporation and ensure the efficiency and uniformity of concentration; at the same time, by continuously stirring the material to maintain the material flow, it can also reduce the product residue on the bottle wall, thereby preventing product loss.

[0018] 2. By setting both the stirring rod and the stirring blade on the tank cover, the stirring rod and the stirring blade can be removed from the concentration tank by removing the tank cover. In this case, the internal space of the concentration tank will be more spacious, which will facilitate the loading and unloading of materials and make it easier to clean the concentration tank after use.

[0019] 3. By setting scrapers on the outside of the stirring blades, the scrapers can continuously scrape the inner wall of the concentration tank during the rotation of the stirring blades, thus preventing the material from adhering to and precipitating on the inner wall of the concentration tank, which would cause inconvenience in product collection. Attached Figure Description

[0020] Figure 1 This is a cross-sectional view of a concentration treatment apparatus for Warburg oxide according to Embodiment 1 of this application;

[0021] Figure 2 This is a top sectional view of the casing of a concentration treatment apparatus for Warburg oxides according to Embodiment 1 of this application;

[0022] Figure 3 This is a cross-sectional view of a concentration treatment apparatus for Warburg oxides according to Embodiment 2 of this application.

[0023] Explanation of icon numbers:

[0024] Concentration tank 1, tank cover 101, stirring rod 2, stirring blade 3, central shaft 4, support column 5, base 6, cover 7, second gear 8, motor 9, machine housing 10, fixing frame 11, collar 12, slide rod 13, first gear 14, first rack 15, sliding sleeve 16, second rack 17, scraper 18. Detailed Implementation

[0025] The technical solution of this utility model will be further described in detail below with reference to the accompanying drawings and specific embodiments. Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this utility model pertains. The terminology used in this specification is for the purpose of describing particular embodiments only and is not intended to limit the utility model.

[0026] Example 1

[0027] See attached document Figure 1-2 This application provides a concentration treatment device for Warwick oxides, including a concentration tank 1. The concentration tank 1 is equipped with a drive mechanism and a stirring mechanism. The stirring mechanism includes a central shaft 4, with several stirring rods 2 arranged on the outer side of the central shaft 4. The central shaft 4 and the stirring rods 2 are equipped with a common stirring blade 3. The drive mechanism drives the stirring rods 2 and stirring blade 3 to rotate reciprocally through the central shaft 4. The stirring rods 2 and stirring blade 3 stir the material through their own motion. The concentration tank 1 is also equipped with a PTFE heating tube and a PC3001 VARIO type vacuum pump controlled by a CVC3000 type vacuum controller. The two work together for depressurized concentration of the material. In addition, the concentration tank 1 is also equipped with a gas pipe for balancing the gas pressure. The gas pipe is equipped with a valve, which allows inert gas to be introduced into the gas pipe after the depressurized concentration is completed to maintain the gas pressure balance in the concentration tank 1.

[0028] Preferably, the top of the concentration tank 1 is provided with a tank cover 101, and a circular opening is provided at the middle of the top of the tank cover 101. The central shaft 4 is rotatably connected to the tank cover 101 at the circular through hole. A cover 7 is fixedly connected to the top of the tank cover 101 outside the central shaft 4. A sealing gasket is provided between the concentration tank 1 and the tank cover 101, and the two are detachably fixedly connected by flanges and bolts.

[0029] When using this device for concentration in the production process of Warburg oxides, the material can be put into the concentration tank 1 after removing the tank cover 101, and then the tank cover 101 can be reinstalled on the concentration tank 1. After that, the heating pipe and vacuum pump on the concentration tank 1 can be turned on, so that the concentration tank 1 is under negative pressure to heat the material, thereby achieving depressurization concentration.

[0030] Preferably, the top of the cover 7 has a circular through hole on the inner side of the fixing frame 11, and the top of the cover 7 is fixedly connected to the housing 10 outside the circular through hole. The driving mechanism includes a motor 9 disposed in the housing 10. The bottom end of the output shaft of the motor 9 extends into the interior of the cover 7 through the circular through hole, and the bottom end of the output shaft of the motor 9 is connected to a first gear 14 by a key. The first gear 14 is an incomplete gear.

[0031] Preferably, two sliding rods 13 are fixedly connected to one end between the inner sides of the cover 7. A collar 12 and a sliding sleeve 16 are respectively fitted onto the outside of the two sliding rods 13. A fixing frame 11 is fixedly connected between the collar 12 and the sliding sleeve 16. The sliding sleeve 16 is located on the side closer to the central shaft 4. A second gear 8 is connected to the top of the central shaft 4 via a key. A second rack 17 is fixedly connected to the side of the sliding sleeve 16 away from the fixing frame 11, and the second rack 17 meshes with the second gear 8. First racks 15 are fixedly connected to the inner walls of both sides of the fixing frame 11, and the first gear 14 meshes with both first racks 15.

[0032] During the concentration process, the motor 9 can be started, which can drive the first gear 14 to rotate. Since the first gear 14 is an incomplete gear, it will mesh with the two first racks 15 respectively during its rotation, so that the fixed frame 11 will reciprocate along the two slide rods 13. The fixed frame 11 drives the second rack 17 to move through the sliding sleeve 16, which can drive the second gear 8 to rotate in both directions. Therefore, the second gear 8 can drive the stirring rod 2 and the stirring blade 3 to swing back and forth in the concentration tank 1 through the central shaft 4.

[0033] Preferably, a base 6 is provided below the concentration tank 1, and several support columns 5 are fixedly connected at equal intervals on the outer side between the concentration tank 1 and the base 6. The bottom of the concentration tank 1 is hemispherical, and the stirring blade 3 is U-shaped to match the concentration tank 1. The stirring blade 3 can also be two U-shaped blades arranged perpendicularly to cross each other, so as to bring a greater stirring effect to the material when rotating.

[0034] In this case, the stirring rod 2 and stirring blade 3 can continuously stir the material, thereby breaking the surface tension of the liquid and making it generate a more chaotic liquid flow, which in turn promotes the uniform distribution of heat in the material, so as to accelerate the evaporation of the solvent. And because the material is heated evenly, the uniformity of its concentration treatment can be guaranteed.

[0035] After the material concentration process is completed, the motor 9, heating tube and air pump can be turned off. Then, after opening the valve, inert gas is introduced into the concentration tank 1 through the air pipe to balance the internal air pressure. After that, the tank cover 101, along with the stirring rod 2 and stirring blade 3, can be removed. Then, the material can be taken out of the concentration tank 1.

[0036] Example 2

[0037] See attached document Figure 3 This application provides a concentrating device for Wöhler oxide. Compared with Example 1, in order to facilitate the collection of the concentrated product, a scraper 18 is fixedly connected to the outer side of the stirring blade 3. The scraper 18 is made of rubber and is a triangular prism with a narrow outer side and a wide inner side.

[0038] As the stirring blade 3 rotates to agitate the material, the scraper 18 rotates along with it and scrapes the inner wall of the concentration tank 1 in real time, so that the material does not stick to and precipitate on the inner wall of the concentration tank 1, thereby facilitating the collection of the product and avoiding losses caused by incomplete material.

[0039] The above are merely specific embodiments of this utility model, but the protection scope of this utility model is not limited thereto. Any variations or substitutions that can be easily conceived by those skilled in the art within the technical scope disclosed in this utility model should be included within the protection scope of this utility model. The protection scope of this utility model shall be determined by the protection scope of the claims.

Claims

1. A concentrating apparatus for Warburg oxides, comprising a concentration tank (1), characterized in that, The concentration tank (1) is equipped with a driving mechanism and a stirring mechanism. The stirring mechanism includes a central shaft (4), and a number of stirring rods (2) are provided on the outside of the central shaft (4). The same stirring blade (3) is provided on the outside of the central shaft (4) and the stirring rods (2). The driving mechanism drives the stirring rods (2) and the stirring blade (3) to rotate back and forth through the central shaft (4). The stirring rods (2) and the stirring blade (3) stir the material through their own movement.

2. The concentrating apparatus for Warburg oxides according to claim 1, characterized in that, The concentration tank (1) is provided with a lid (101) at the top. A circular opening is provided at the middle of the top of the lid (101). The central shaft (4) is rotatably connected to the lid (101) at the circular through hole. A cover (7) is fixedly connected to the top of the lid (101) outside the central shaft (4).

3. The concentrating apparatus for Warburg oxides according to claim 2, characterized in that, Two sliding rods (13) are fixedly connected at one end between the inner sides of the cover (7). The two sliding rods (13) are respectively fitted with a collar (12) and a sliding sleeve (16). A fixing frame (11) is fixedly connected between the collar (12) and the sliding sleeve (16).

4. The concentrating apparatus for Warburg oxides according to claim 3, characterized in that, The sliding sleeve (16) is located on the side close to the central shaft (4). The top of the central shaft (4) is connected to the second gear (8) by a key. The sliding sleeve (16) is fixedly connected to the side away from the fixed frame (11) with the second rack (17) meshing with the second gear (8).

5. The concentrating apparatus for Warburg oxides according to claim 3, characterized in that, The top of the cover (7) has a circular through hole on the inner side of the fixing frame (11), and the top of the cover (7) is fixedly connected to the housing (10) outside the circular through hole. The driving mechanism includes a motor (9) disposed in the housing (10).

6. The concentrating apparatus for Warburg oxides according to claim 5, characterized in that, The bottom end of the output shaft of the motor (9) extends into the interior of the cover (7) through the circular through hole. The bottom end of the output shaft of the motor (9) is connected to a first gear (14) by a key. The first gear (14) is an incomplete gear.

7. The concentrating apparatus for Warburg oxides according to claim 6, characterized in that, The inner walls on both sides of the fixed frame (11) are fixedly connected with first racks (15), and the first gear (14) meshes with both first racks (15).

8. The concentrating apparatus for Warburg oxides according to claim 1, characterized in that, A base (6) is provided below the concentration tank (1). Several pillars (5) are fixedly connected at equal intervals on the outer side between the concentration tank (1) and the base (6). The bottom of the concentration tank (1) is hemispherical. The stirring blade (3) is U-shaped to match the concentration tank (1).

9. The concentrating apparatus for Warburg oxides according to claim 8, characterized in that, A scraper (18) is fixedly connected to the outside of the stirring blade (3). The scraper (18) is made of rubber and is a triangular prism with a narrow outer side and a wide inner side.

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