Felodipine reaction kettle with protective structure

Abstract

The utility model discloses a non - furosemide reation kettle of protection structure, specifically at related to pharmaceutical preparation technical field, including the reation kettle, the reation kettle top is equipped with the sealing cover, the sealing cover top is fixedly connected with the feed pipe, the reation kettle top is provided with the heat exchange protection mechanism, the heat exchange protection mechanism includes the fixed box, the fixed box is fixed in the sealing cover top, the sealing cover top is fixedly installed with the heat exchange box in the fixed box one side, the utility model discloses through circulating pump drive coolant circulation, realizes the efficient heat exchange to the reation kettle, and the air release valve opens and makes the high -temperature gas through the air release pipe and enters the heat exchange box, and its heat is absorbed by coolant, reduces gas temperature and maintains the pressure stability in the reation kettle, ensures that non - furosemide production reaction is carried out under the suitable temperature and pressure condition, improves product quality and production efficiency, avoids the scald, fire and other safety problems that high -temperature gas direct emission brings, provides the protection effect.

Description

Technical Field

[0001] This utility model relates to the field of drug preparation technology, and more specifically, to a felodipine reaction vessel with a protective structure. Background Technology

[0002] Felodipine is a commonly used drug for treating mild to moderate essential hypertension and stable angina. Its production process is crucial, and the reaction vessel is one of the key pieces of equipment in the production of felodipine.

[0003] Existing felodipine reactors require pressure relief and venting during use. When the pressure inside the reactor increases due to heat accumulation, there is a lack of an effective heat and pressure balance mechanism. Direct discharge of high-temperature gas can easily cause safety accidents such as burns and fires. At the same time, the high-temperature reactor is exposed to the outside environment, which can easily lead to personnel coming into direct contact with the high-temperature outer wall of the reactor, causing burn accidents. The protection effect is insufficient. Utility Model Content

[0004] In order to overcome the problems and defects in the prior art, this utility model provides a nonlodipine reactor with a protective structure to solve the problems mentioned in the background art.

[0005] To achieve the above objectives, this utility model provides the following technical solution: a protective structure for a nonlodipine reaction vessel, comprising a reaction vessel, a sealing cover plate installed on the top of the reaction vessel, a feed pipe fixedly connected to the top of the sealing cover plate, and a heat exchange protection mechanism provided on the top of the reaction vessel;

[0006] The heat exchange protection mechanism includes a fixed box, which is fixed to the top of the sealing cover. A heat exchange box is fixedly installed on the top of the sealing cover near the fixed box. A circulating pump and a water-cooled block are installed inside the fixed box. A heat exchange tube is installed inside the heat exchange box. A connecting pipe is fixedly connected between the heat exchange tube, the circulating pump, and the water-cooled block. An exhaust pipe is fixedly connected to the top of the heat exchange box. A valve is installed inside the exhaust pipe. A vent pipe is fixedly connected between the heat exchange box and the sealing cover. A vent valve is installed inside the vent pipe. A protection mechanism is provided on the outside of the reaction vessel.

[0007] Preferably, the protective mechanism includes a protective sleeve, which is fixedly fitted onto the outside of the reactor, and a fixing box is fixedly connected to the outside of the protective sleeve.

[0008] Preferably, a spring is fixedly connected to one side of the inner wall of the fixing box, and a movable plate is fixedly connected to one end of the spring, with the movable plate slidably connected to the inner wall of the fixing box.

[0009] Preferably, a movable rod is fixedly connected to the top of the movable plate, the movable rod is slidably connected to the fixed box, and a protective plate is fixedly connected to one end of the movable rod.

[0010] Preferably, a fixed column is fixedly connected to the bottom of the reactor, and a fixed bottom box is provided at the bottom of the fixed column.

[0011] Preferably, a rubber plate is fixedly connected to the bottom of the inner wall of the fixed base box, the top of the rubber plate is fixedly connected to the fixed column, and the fixed column is slidably connected to the fixed base box.

[0012] Preferably, the heat exchange tube is made of aluminum alloy, and the bottom of the vent pipe passes through the sealing cover and extends to the bottom of the sealing cover.

[0013] The technical effects and advantages of this utility model are as follows:

[0014] 1. The circulating pump drives the coolant circulation to achieve efficient heat exchange in the reactor. When the pressure inside the reactor increases due to heat accumulation, the vent valve opens, allowing high-temperature gas to enter the heat exchange box through the vent pipe. Its heat is absorbed by the coolant, which both reduces the gas temperature and maintains stable pressure inside the reactor. This ensures that the felodipine production reaction takes place under suitable temperature and pressure conditions, improving product quality and production efficiency. At the same time, the exhaust pipe discharges the cooled gas under valve control, further maintaining internal pressure balance and avoiding safety issues such as burns and fires caused by direct discharge of high-temperature gas, thus providing a protective effect.

[0015] 2. The protective sleeve is tightly fitted onto the outside of the reactor, providing a basic protective barrier. It can effectively block damage to the reactor body from external scratches and collisions. When subjected to strong external impacts, the buffer structure composed of the protective plate, moving rod, moving plate, and springs plays its role. The springs absorb the impact force through elastic deformation, dispersing and buffering the impact force, greatly reducing the impact force transmitted to the reactor, protecting the structural integrity of the reactor, reducing the risk of reactor body rupture and leakage caused by external impacts, extending the service life of the reactor, avoiding burns caused by direct contact with the high-temperature outer wall of the reactor, and improving the protective effect. Attached Figure Description

[0016] Figure 1 This is a schematic diagram of the overall structure of this utility model.

[0017] Figure 2 This is a partial structural schematic diagram of the present invention.

[0018] Figure 3 For the present utility model Figure 2 Rear view structural diagram.

[0019] Figure 4 This is a cross-sectional view of the present invention.

[0020] Figure 5 This is a partial cross-sectional view of the present invention.

[0021] Figure 6 This is a side sectional view of the present invention.

[0022] The attached diagram is labeled as follows: 1. Reactor; 2. Sealing cover; 3. Feed pipe; 4. Fixed box; 5. Heat exchange box; 6. Connecting pipe; 7. Heat exchange tube; 8. Circulating pump; 9. Water cooling block; 10. Exhaust pipe; 11. Valve; 12. Vent pipe; 13. Vent valve; 14. Protective sleeve; 15. Fixed box; 16. Spring; 17. Moving plate; 18. Moving rod; 19. Protective plate; 20. Fixed column; 21. Fixed base box; 22. Rubber plate. Detailed Implementation

[0023] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0024] As attached Figure 1-6 The protective structure of the nonlodipine reactor shown includes a reactor 1, a sealing cover plate 2 installed on the top of the reactor 1, a feed pipe 3 fixedly connected to the top of the sealing cover plate 2, and a heat exchange protection mechanism provided on the top of the reactor 1.

[0025] The heat exchange protection mechanism includes a fixed box 4, which is fixed to the top of the sealing cover plate 2. A heat exchange box 5 is fixedly installed on the top of the sealing cover plate 2 near the fixed box 4. A circulating pump 8 and a water-cooled block 9 are installed inside the fixed box 4. A heat exchange tube 7 is installed inside the heat exchange tube 7, the circulating pump 8 and the water-cooled block 9 are fixedly connected by a connecting pipe 6. An exhaust pipe 10 is fixedly connected to the top of the heat exchange box 5. A valve 11 is installed inside the exhaust pipe 10. A vent pipe 12 is fixedly connected between the heat exchange box 5 and the sealing cover plate 2. A vent valve 13 is installed inside the vent pipe 12. A protection mechanism is provided on the outside of the reaction vessel 1.

[0026] As attached Figure 1 , 2As shown in Figures 3, 4, and 6, the protective mechanism includes a protective sleeve 14, which is fixedly fitted onto the outside of the reactor 1. A fixed box 15 is fixedly connected to the outside of the protective sleeve 14. A spring 16 is fixedly connected to one side of the inner wall of the fixed box 15. A movable plate 17 is fixedly connected to one end of the spring 16. The movable plate 17 is slidably connected to the inner wall of the fixed box 15. A movable rod 18 is fixedly connected to the top of the movable plate 17. The movable rod 18 is slidably connected to the fixed box 15. A protective plate 19 is fixedly connected to one end of the movable rod 18. This mechanism prevents personnel from directly contacting the high-temperature reactor 1 and causing burns, and effectively avoids external impacts.

[0027] As attached Figure 1 , 6 As shown, a fixed column 20 is fixedly connected to the bottom of the reactor 1, and a fixed base box 21 is provided at the bottom of the fixed column 20. A rubber plate 22 is fixedly connected to the bottom of the inner wall of the fixed base box 21. The top of the rubber plate 22 is fixedly connected to the fixed column 20, and the fixed column 20 and the fixed base box 21 are slidably connected to each other, which facilitates buffering of the reactor 1 and provides protection for the reactor 1.

[0028] As attached Figure 5 , 6 As shown, the heat exchange tube 7 is made of aluminum alloy to ensure heat exchange effect and effectively reduce the temperature of the exhaust gas. The bottom of the vent pipe 12 passes through the sealing cover plate 2 and extends to the bottom of the sealing cover plate 2. The vent pipe 12 facilitates pressure relief and gas release.

[0029] The working principle of this utility model is as follows: The fixed box 4 and the heat exchange box 5 constitute the main heat exchange structure. After the circulation pump 8 is started, it drives the coolant to circulate in the connecting pipe 6. The coolant first absorbs heat through the water cooling block 9 and then flows into the heat exchange tube 7. Since the heat exchange tube 7 is made of aluminum alloy, it has good thermal conductivity and can efficiently transfer the heat in the reactor 1 to the coolant. When too much heat is generated during the reaction process, causing the pressure in the reactor 1 to rise, the vent valve 13 is opened. The gas in the reactor 1 enters the heat exchange box 5 through the vent pipe 12. The heat of the gas is also absorbed by the coolant in the heat exchange tube 7, reducing the gas temperature. After heat exchange, the coolant carries the heat back to the water cooling block 9 for cooling, realizing heat circulation and exchange. Under the control of the valve 11, the exhaust pipe 10 can discharge the cooled gas in the heat exchange box 5 to maintain internal pressure balance and avoid the direct discharge of high-temperature gas, which may cause safety problems.

[0030] The protective sleeve 14 is tightly fitted onto the outside of the reactor 1, providing basic protection for the reactor. When the reactor 1 is subjected to external impact, the impact force first acts on the protective plate 19. The protective plate 19 transmits the force to the moving plate 17 through the moving rod 18. The moving plate 17 compresses the spring 16, and the spring 16 undergoes elastic deformation to absorb the impact force, thereby reducing the impact force on the reactor 1 and protecting the reactor structure. The fixing box 15 provides installation space and support for components such as the spring 16 and the moving plate 17, ensuring the stable operation of the protective mechanism. The fixing column 20 at the bottom of the reactor 1 is inserted into the fixing base box 21 to support the reactor. The rubber plate 22 at the bottom of the inner wall of the fixing base box 21 is connected to the fixing column 20. The rubber plate 22 has good elasticity and generates vibration buffer during reactor operation, which can damage the reactor. At the same time, it can effectively prevent personnel from directly contacting the high-temperature outer wall of the reactor 1, thus improving the protective effect.

[0031] In conclusion, the above embodiments are merely illustrative of the principles and effects of this utility model and are not intended to limit the scope of this utility model. Any person skilled in the art can modify or alter the above embodiments without departing from the spirit and scope of this utility model. Therefore, all equivalent modifications or alterations made by those skilled in the art without departing from the spirit and technical concept disclosed in this utility model should still be covered by the claims of this utility model.

Claims

1. A protective structure for a nonlodipine reactor, comprising a reactor (1), characterized in that: The top of the reactor (1) is equipped with a sealing cover plate (2), and the top of the sealing cover plate (2) is fixedly connected with a feed pipe (3). The top of the reactor (1) is equipped with a heat exchange protection mechanism. The heat exchange protection mechanism includes a fixed box (4), which is fixed on the top of the sealing cover plate (2). A heat exchange box (5) is fixedly installed on the top of the sealing cover plate (2) near the fixed box (4). A circulating pump (8) and a water-cooled block (9) are installed inside the fixed box (4). A heat exchange tube (7) is installed inside the heat exchange box (5). A connecting pipe (6) is fixedly connected between the heat exchange tube (7), the circulating pump (8), and the water-cooled block (9). An exhaust pipe (10) is fixedly connected to the top of the heat exchange box (5). A valve (11) is installed inside the exhaust pipe (10). A vent pipe (12) is fixedly connected between the heat exchange box (5) and the sealing cover plate (2). A vent valve (13) is installed inside the vent pipe (12). A protection mechanism is provided on the outside of the reactor (1).

2. The nonlodipine reactor with the protective structure according to claim 1, characterized in that: The protective mechanism includes a protective sleeve (14), which is fixedly fitted on the outside of the reactor (1), and a fixed box (15) is fixedly connected to the outside of the protective sleeve (14).

3. The nonlodipine reactor with protective structure according to claim 2, characterized in that: A spring (16) is fixedly connected to one side of the inner wall of the fixed box (15), and a movable plate (17) is fixedly connected to one end of the spring (16). The movable plate (17) is slidably connected to the inner wall of the fixed box (15).

4. The nonlodipine reactor with the protective structure according to claim 3, characterized in that: The top of the movable plate (17) is fixedly connected to a movable rod (18), which is slidably connected to the fixed box (15). One end of the movable rod (18) is fixedly connected to a protective plate (19).

5. The nonlodipine reactor with the protective structure according to claim 1, characterized in that: The bottom of the reactor (1) is fixedly connected to a fixed column (20), and a fixed bottom box (21) is provided at the bottom of the fixed column (20).

6. The nonlodipine reactor with the protective structure according to claim 5, characterized in that: A rubber plate (22) is fixedly connected to the bottom of the inner wall of the fixed base box (21). The top of the rubber plate (22) is fixedly connected to the fixed column (20). The fixed column (20) is slidably connected to the fixed base box (21).

7. The nonlodipine reactor with protective structure according to claim 1, characterized in that: The heat exchange tube (7) is made of aluminum alloy, and the bottom of the vent pipe (12) passes through the sealing cover plate (2) and extends to the bottom of the sealing cover plate (2).

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