DEVICE FOR STORING AND TRANSPORTING A TRANSPLANT OR IMPLANT

Abstract

Device for storing and transporting a graft (4) or implant, comprising a container (2) that can be filled with a medium (1), preferably a nutrient medium, and a receiving device (3) for the graft (4) or implant that can be arranged in the container (2), wherein the receiving device (3) has a receiving chamber (5) for the graft (4) or implant and two passages (6, 7) leading to the receiving chamber (5), at least one of which (6, 7) is dimensioned for inserting and / or removing the graft (4) or implant into or from the receiving chamber (5), and each of which has a closure device (8, 9) for the two passages (6, 7), at least one of which (8, 9) is permeable to the medium (1), characterized in that at least one of the two closure devices (8, 9) has a grid to provide permeability to the medium (1).

Description

[0001] The present invention relates to a device for storing and transporting a graft or implant, comprising a container fillable with a medium, preferably a nutrient medium, and a receiving device for the graft or implant that can be arranged in the container. The receiving device has a receiving chamber for the graft or implant and two passages leading to the receiving chamber, at least one of which is dimensioned for inserting and / or removing the graft or implant into or from the receiving chamber. Each of the two passages has a closure device, at least one of which is permeable to the medium. Preferably, both closure devices are impermeable to the graft or implant for transport purposes.

[0002] Furthermore, the present invention relates to a corresponding receiving device and a set comprising a device as described above in a sterilized state or in packaging suitable for sterilization.

[0003] Human corneal transplantation is among the most frequently performed and successful transplant surgeries. Transplantation of the cornea using all its layers (epithelium, Bowman's membrane, stroma, Descemet's membrane, and endothelial cell layer) via penetrating keratoplasty has been known for over 100 years. This surgical method generally achieves good results; however, recovery is very lengthy, and complete visual recovery is usually only achieved after the removal of the second suture. This can take up to 18 months after the procedure.

[0004] Roughly half of all corneal transplants are performed due to diseases of the corneal endothelium. In principle, layer-specific corneal replacement would be suitable for these diseases. Appropriate techniques for this are now available. For several years now, transplantation of the Descemet membrane with an attached stromal flap (DSAEK) has enabled a much faster visual recovery and, consequently, greater patient satisfaction compared to penetrating keratoplasty.

[0005] For the treatment of corneal diseases affecting the corneal endothelium, a novel, specialized form of corneal transplantation has been described. This is Descemet Membrane Endothelial Keratoplasty (DMEK). During this procedure, the diseased endothelial cells, including the underlying Descemet membrane, can be removed and replaced with a Descemet membrane containing healthy donor corneal endothelium. Penetrating keratoplasty is not required; instead, the graft can be transferred into the anterior chamber of the eye through a relatively small incision and carefully spread out. The membrane preparation is then fixed to the posterior stroma by adding air.

[0006] A successful DMEK operation allows the patient a very rapid visual rehabilitation. It can be assumed that the patient will achieve full visual acuity approximately two months after the procedure.

[0007] In general, a whole range of surgical and especially ophthalmological procedures are known or conceivable in which a transplant or implant is provided and inserted into the living body. For the sake of rapid patient recovery—as exemplified above by the DMEK procedure—it is advantageous to insert a transplant or implant into the living body through an incision of limited, and especially as small, size as possible.

[0008] From DE 10 2010 051 458 A1, for example, a device for providing and inserting a transplant or implant into the living body, particularly for ophthalmic procedures, is known. The device described here has a cartridge or sleeve with two opposing end openings, wherein this cartridge or sleeve is particularly suitable for inserting a transplant or implant into a patient's body through a very small incision, as is required, for example, in the ophthalmic application described above.

[0009] Of particular importance for successful medical application is the safe storage and transport of the transplant or implant. However, not only is safe storage and transport of the transplant or implant important, but also its simple and safe transfer from storage and / or transport to the point of use. Damage and / or contamination of the transplant or implant must be prevented in this process.

[0010] Furthermore, a device with all the features of the preamble of claim 1 is known from US 7 662 611 B2.

[0011] Furthermore, US 2009 / 0270982A1 discloses a device for storing and transporting a graft or implant, comprising a container that can be filled with a medium, a receiving device for the graft or implant that can be arranged in the container, and the receiving device having a receiving space for the graft or implant and two passages leading to the receiving space.

[0012] The present invention is based on the objective of providing a device, a receiving device and a set with such a device, according to which safe storage and / or safe transport as well as safe and easy provision of the transplant or implant for insertion into the human or animal body are enabled.

[0013] According to the invention, the foregoing problem is solved by a device having the features of claim 1, by a receiving device having the features of claim 7 and by a set having the features of claim 10.

[0014] The device according to the invention is ideally suited for both storing and transporting a transplant or implant. For this purpose, the device comprises a container that can be filled with a medium, preferably a nutrient medium, and a receiving device for the transplant or implant that can be arranged in the container. The transplant or implant is thus arranged in a separate receiving device within the container, the receiving device having a receiving chamber for the transplant or implant and two passages leading to the receiving chamber. At least one of these two passages is dimensioned for inserting and / or removing the transplant or implant into or from the receiving chamber. Insertion and / or removal of the transplant or implant into or from the receiving chamber is carried out through the same passage.To ensure the secure positioning of the graft or implant within the receiving chamber, the device also features a closure mechanism for each of the two openings. This prevents the graft or implant from escaping the receiving chamber into the container or into the medium typically stored and transported within the container. This ensures safe handling of the graft or implant using the receiving device and simultaneously protects the graft or implant and receiving device within the container. At least one of the two closure mechanisms is permeable to the medium, but not to the graft or implant itself.This ensures safe contact between the transplant or implant and the medium during storage and / or transport, as a sufficient amount of medium can always enter the receiving chamber to the transplant or implant through the closure device, which is permeable to the medium.

[0015] According to the invention, at least one of the two closure devices, and preferably both closure devices, has a grid to provide permeability for the medium. When the graft or implant is positioned in the receiving chamber, such a closure device provides, on the one hand, reliable protection against unintentional slippage of the graft or implant from the receiving chamber and, on the other hand, provides the necessary permeability for the medium to adequately wet or rinse the graft or implant. For particularly reliable introduction of the medium into the receiving chamber or flushing through the receiving chamber, both closure devices have such a grid. The grid can advantageously be an integral part of the respective closure device.

[0016] In a particular embodiment, one of the two locking devices can be formed by a narrowing of the receiving device or a passage. In this respect, one of the two locking devices can be realized as an integral part of the receiving device.

[0017] Due to the separate handling of the receiving device with the transplant or implant arranged therein, the device according to the invention is also ideally suited to making the transplant or implant available for surgical use and thus for insertion into the human or animal body after storage and / or transport.

[0018] Consequently, the device according to the invention is a device which enables safe storage and / or safe transport as well as safe and easy provision of the transplant or implant for insertion into the human or animal body.

[0019] With a view to ensuring particularly safe and easy delivery of the graft or implant, and with regard to a particularly simple design of the receiving device, the receiving device can be designed as a sleeve or cylinder. The receiving space for the graft or implant is formed by the interior of the sleeve or cylinder, and the two passages are formed by the openings at the ends of the sleeve or cylinder. These passages are usually of the same size, so that the graft or implant can be inserted into and / or removed from the receiving space through either passage. Therefore, it is not necessary to ensure the correct orientation of the receiving device for inserting and / or removing the graft or implant.

[0020] The locking devices can be attached to the receiving device in a particularly simple and flexible manner. This ensures exceptionally easy handling of the device, with the locking devices typically being attached to the receiving device by hand or using very simple tools. Advantageously, the locking devices can be designed as cuffs that can be at least partially slid or attached to the receiving device.

[0021] To facilitate easy positioning of the locking devices on the receiving device, the locking devices can be made of at least slightly elastic material, preferably plastic. Due to the elasticity of the locking device material, the locking devices can be positioned under preload on the receiving device if appropriately dimensioned. Multiple uses of the locking devices are possible.

[0022] With regard to further functions, the receiving device, or at least one of the two closure devices for connecting a cuff or adapter, or with an integrated adapter or adapter area, can be designed such that a hose, a syringe (preferably a disposable syringe), or a device for supplying and / or draining the medium and / or another fluid medium, preferably a staining solution, can be connected. On the one hand, the receiving device can be designed for connecting a cuff or adapter, or with an integrated adapter or adapter area. On the other hand, this adaptation option can be provided by a closure device already coupled to the receiving device. For example, connecting a hose with a syringe attached to it can allow a staining solution to be introduced into the receiving chamber.The medium already present in the receiving chamber can be flushed out or mixed with the staining solution. Alternatively, the attached tube and syringe can be used to create a suction or push action to move the graft or implant within or out of the receiving chamber. For this application, a closure device with a grid must be replaced with one without a grid. In another application, a known cartridge or sleeve for supplying and inserting a graft or implant can be coupled to the receiving device. A tube with a syringe can then be connected to this cartridge or sleeve, allowing the graft or implant to be moved into the cartridge or sleeve by means of a suction or push action when the syringe plunger is actuated.All of the aforementioned applications can be implemented very simply by means of suitable closure devices, cuffs, adapters or adapter areas, whereby instead of a syringe, a suitable device for supplying and / or removing the medium and / or another fluid medium can be used as an alternative.

[0023] The receiving device can advantageously be made of plastic, glass, or metal. The choice of material depends on the specific application. For example, a transparent design allows for reliable observation and monitoring of the position of the graft or implant within the receiving chamber. A design made of glass or metal enables safe reuse of the receiving device, as devices made of these materials are particularly easy to clean and / or sterilize. A design made of plastic is usually the most cost-effective, although in this case, single use is possible.

[0024] The foregoing problem is further solved by a receiving device with the features of dependent claim 7, wherein the receiving device has a closure device for each of the two passages, at least one of which is permeable to the medium, and wherein at least one of the two closure devices has a grid to provide permeability to the medium. Regarding the advantages of such a receiving device, reference is made to the preceding explanations to avoid repetition, from which the advantages of the receiving device can be derived.

[0025] A particularly advantageous feature is the coupling of a cartridge or sleeve with two opposing end openings to one of the two ports, the first opening having a larger diameter than the second. This combination of receiving device and coupled cartridge or sleeve enables not only the safe storage or transport of a graft or implant, but also its easy preparation for insertion, for example, by means of a syringe or device for supplying and / or draining the medium and / or another fluid medium coupled to the other of the two ports of the receiving device.

[0026] The foregoing combination of receiving device and cartridge or sleeve can be provided to a surgeon with the graft or implant arranged therein for direct insertion of the graft or implant into the human or animal body.

[0027] The cartridge or sleeve can be advantageously designed such that the outer edge of the second opening can be inserted into the nozzle of a syringe and / or that the first opening can be attached to the nozzle of the same or another syringe. If the outer edge of the second opening is inserted into the nozzle of a syringe, a vacuum can be created via the syringe, which draws the graft or implant from a receiving device coupled to the first opening into the cartridge or sleeve. The sleeve or cartridge can then be detached from the receiving device and attached, with the first opening, to the nozzle of the same or another syringe.The transplant or implant is thus ready for insertion into the human or animal body, whereby actuating the syringe can generate a suitable thrust for inserting the transplant or implant into the human or animal body.

[0028] Alternatively, a syringe can be attached to the end of a receiving device coupled to the cartridge or sleeve opposite the cartridge or sleeve. This would provide a combination of a coupled cartridge or sleeve, receiving device, and syringe. The coupling between these three elements can be achieved using suitable cuffs and / or adapters. In this case, pushing the syringe plunger in exerts a thrust on the graft or implant within the receiving device's chamber, moving it into the cartridge or sleeve and allowing it to be inserted or injected further into the human or animal body. In this case, it is not necessary to disconnect the cartridge or sleeve from the receiving device before inserting the graft or implant into the body.

[0029] The aforementioned problem is also solved by a set with the features of claim 10. Such a set comprises a device according to one of the preceding claims, wherein this device is located in a sterilized state or in packaging suitable for sterilization for safe and convenient provision. Regarding the advantages of the device comprised of the set, reference is made to the preceding explanations of the device according to the invention to avoid repetition. The advantageous effects described therein apply equally to the set according to the invention.

[0030] In a further advantageous way, the set can also include a syringe and an adapter and / or hose suitable for connection to the device, thus enabling different applications of the set's components.

[0031] Alternatively or additionally, the receiving device can already contain a transplant or implant. In this respect, a ready-to-use set can be provided within the scope of the present invention.

[0032] There are now various ways to advantageously develop and further refine the teaching of the present invention. Reference is made, on the one hand, to the dependent claims and, on the other hand, to the following explanation of preferred embodiments of the device, the receiving device, and the set according to the invention. In conjunction with the explanation of the preferred embodiments with reference to the drawing, generally preferred embodiments and further developments of the teaching are also explained. The drawing shows Fig. 1 in a schematic representation an embodiment of a device according to the invention for storing and transporting a transplant or implant with an attached syringe, Fig. 2 in a schematic representation the exemplary embodiment from Fig. 1, wherein a closure device is replaced with a cuff suitable for adaptation, Fig. 3 in a schematic representation a receiving device arranged in the container with the according to Fig. 2 attached cuffs and a cartridge or sleeve attached via the cuff for providing and introducing the transplant into the body, Fig. 4 in a schematic representation the arrangement of Fig. 3, wherein a hose and a syringe are additionally coupled to the cartridge or sleeve, Fig. 5 in a schematic representation the arrangement of Fig. 4, wherein the transplant has been moved into the cartridge or sleeve by means of actuating the syringe, Fig. 6 in a schematic representation the arrangement of Fig. 5, wherein the receiving device and the cuff are removed from the cartridge, Fig. 7 in a schematic representation the arrangement of Fig. 6, with another syringe inserted into the cartridge, Fig. 8 in a schematic representation the arrangement of Fig. 7, wherein the tube is removed from the cartridge, so that the graft or implant can be introduced into the body using the cartridge, Fig. 9 in a schematic representation the starting point of a further variant for handling the device according to the invention, wherein this representation is the representation according to Fig. 1 corresponds to Fig. 10 in a schematic representation the arrangement of Fig. 9, wherein the syringe with adapter is removed and a closure device on the opposite side is replaced with a cuff suitable for adaptation, Fig. 11 in a schematic representation the arrangement of Fig. 10, wherein a cartridge for providing and introducing the transplant into the body is attached to the Fig. 10 attached cuff is attached, and Fig. 12 in a schematic representation the arrangement of Fig. 11, wherein an adapter and a syringe are coupled to the end of the receiving device facing away from the cartridge, so that the transplant or implant can be introduced directly into the body with this arrangement.

[0033] Fig. Figure 1 shows a schematic side view of an embodiment of a device according to the invention for storing and transporting a transplant or implant. The device comprises a container 2 that can be filled with a medium 1 and a receiving device 3 that can be arranged in the container 2 for the transplant 4 or implant. For the sake of simplicity, the term "transplant" will be used in the following, but this always refers to an implant as an alternative.

[0034] The receiving device 3 has a receiving chamber 5 for the graft 4 and two passages 6, 7 leading to the receiving chamber 5. The receiving device 3 is designed as a cylinder, such that both passages 6, 7 are dimensioned for inserting and / or removing the graft 4 into or from the receiving chamber 5. Both passages 6, 7 are each equipped with a closure device 8, 9, both closure devices 8, 9 being permeable to the medium 1.

[0035] To load the receiving device 3 with the graft 4, the cylindrical receiving device 3 is first closed on one side with a closure device 9, which is permeable to the medium 1 but prevents the passage of the graft 4. An adapter 10 is then coupled to the closure device 9, and a syringe 11 is connected to the adapter 10. By pulling out the plunger of the syringe 11, the graft 4 is drawn in through the still-open passage 6. The receiving device 3 is then closed with another closure device 8 at the still-open passage 6, and the syringe 11 is removed along with the adapter 10. The receiving device 3 is now loaded with the graft 4 and ready for transport.

[0036] Alternatively, a hose can be connected between the adapter 10 and the closure device 9. This means that the syringe 11 is not directly connected to the receiving device 3 via the adapter 10 and the closure device 9, but also via the hose.

[0037] The container 2 can be in the form of a bottle with a bottle closure, for example, a screw cap. Such a bottle-shaped container 2 can advantageously be used for transporting or shipping the transplant 4. Alternatively, the container 2 can also be designed as an open and optionally closable tray. For easy handling of the receiving device 3 arranged in the container 2, a handling element, for example, a plastic strip, can be attached to the receiving device 3 or to a closure device 8 or 9, with which the receiving device 3 can be easily pulled out of the opening of the bottle-shaped container 2.The handling element can be fixed in the area of ​​the bottle neck or the bottle opening so that, after removing the bottle cap, the handling element can be easily grasped and the receiving device 3 can be pulled out of the bottle or container 2. For easy handling of the receiving device 3, it can be placed in a tray after removal from the container 2, and the medium 1 contained in the container 2 can also be tipped into this tray. This ensures good accessibility to the receiving device 3 and to the transplant 4.

[0038] The closure devices 8 and 9 can be attached to the receiving device 3 and are essentially designed as cuffs. Both closure devices 8 and 9 are made of an elastic plastic. Each closure device 8 and 9 has a mesh to allow passage of the medium 1 or another medium. This mesh, however, prevents the graft 4 from exiting the receiving device 3.

[0039] Fig. Figure 1, however, does not show the loading process of the receiving device 3 described above, but rather the staining of the graft 4. Different syringes 11 are typically used for loading and staining the graft 4. Both the loading of the receiving device 3 and the staining of the graft 4 take place in the container 2 filled with the medium 1. The arrow in Fig. Figure 1 indicates that a staining solution from the syringe 11 is introduced through the adapter 10 and the mesh-equipped closure device 9, via the passage 7, into the receiving chamber 5. Since both closure devices 8 and 9 are permeable to the medium 1 and the staining solution, but ensure the placement of the graft 4 within the receiving chamber 5 due to their mesh design, staining and rinsing of the graft 4 is possible simply and safely by actuating the plunger of the syringe 11. During the rinsing and / or staining process, the entire receiving device 3, including the graft 4, remains immersed in the medium 1.

[0040] The sealing devices 8 and 9, which are equipped with grids, ensure sufficient circulation of the medium 1 through the receiving device 3 during transport of the device.

[0041] After the dyeing process, according to Fig. 2. The closure device 9 is replaced with a cuff 16, which has no mesh and allows the graft 4 to pass through the opening 7 and the cuff 16. For this purpose, the cuff 16 is attached to the receiving device 3 instead of the closure device 9.

[0042] In the next step, according to Fig. 3. A sleeve or cartridge 12 known from DE 10 2010 051 458 A1 is inserted into an adapter area of ​​the cuff 16 to provide a flow connection from the receiving chamber 5 through the cuff 16 into the cartridge 12. The cartridge 12 has a larger opening 13 located in the cuff 16. At the opposite end, the cartridge 12 has an opening 14 with a smaller diameter than the opening 13. This end of the cartridge 12 with the opening 14 is used for insertion into an incision in the human or animal body for the introduction of the graft 4.

[0043] According to Fig. In the next step, a hose 15 is inserted over the opening 14 of the cartridge 12. An adapter 10 with a syringe 17 is attached to the other end of the hose 15. The syringe 17 is filled with a small amount of liquid, for example, a saline solution. Care must be taken to ensure a connection free of air bubbles.

[0044] According to Fig. 5. The graft 4 was moved into the cartridge 12 by carefully pulling back the plunger of the syringe 17. Care must be taken to ensure that the graft 4 is not drawn in too quickly, as it could otherwise become jammed in the narrow part of the cartridge 12, risking damage to the graft 4.

[0045] All of the above steps take place with the recording device 3 introduced into the medium 1.

[0046] In the next step, the tube 15 and the cuff 16 with the receiving device 3 can be removed from the cartridge 12. The cartridge 12, with its larger opening 13, can then be attached to a syringe nozzle. This makes the cartridge, with the graft 4 inside it, ready for the graft 4 to be introduced into the body.

[0047] The Fig. 6, Fig. 7 to Fig. Figure 8 shows a schematic representation of one possible handling method, starting from the one in Fig. The situation shown in Figure 5 ends with a cartridge 12 attached to a syringe 18. Specifically, according to Fig. 6. First, the cuff 16 with the receiving device 3 is removed from the cartridge 12. Then, according to Fig. 7 Another syringe 18 is inserted into the larger opening 13 of the cartridge 12. Then, according to Fig. 8. Tube 15 with adapter 10 and syringe 17 removed from cartridge 12. The remaining assembly is now ready for direct insertion of the graft 4 into the body.

[0048] Alternatively to the one according to the Fig. 4 and Fig. The process of inserting the graft 4 into the cartridge 12 shown in Figure 5 can, for example, involve attaching a syringe – with or without tubing – to the passage 6 of the receiving device 3, as described in Figure 5. Fig. The situation and arrangement shown in Figure 3 are shown. For this coupling of the syringe, the closure device 8 is preferably replaced by a suitable cuff or adaptation device permeable to a medium 1 or another liquid. In this alternative embodiment, the graft 4 can be moved into the cartridge 12 by appropriately pushing the piston of the syringe, which is coupled in the area of ​​the passage 6, through the cuff 16 and the opening 13 of the cartridge 12. The graft 4 is thus also ready for insertion into the body via the cartridge 12 and its smaller second opening 14. With this second provision option, one of the previously mentioned openings in the Fig. 4 and Fig. As described in section 5, separate insertion or loading of the graft 4 into the cartridge 12 is unnecessary. Simply by connecting a suitable syringe to the end of the receiving device 3 opposite the cartridge 12, the device is essentially ready to introduce the graft 4 into the body using the cartridge 12.

[0049] According to a further embodiment, the final arrangement described in the preceding paragraph can also be combined with the one described in the Fig. 9, Fig. 10, Fig. 11 to Fig. The sequence of arrangement steps shown in 12 will lead to this. This is based on the in Fig. The arrangement shown in 9 is taken as a starting point, which is the one in Fig. corresponds to the arrangement shown in 1.

[0050] According to Fig. 10. The closure device 8 is replaced by a cuff 16 and the adapter 10 and the syringe 11 are removed from the closure device 9.

[0051] According to Fig. 11 then connects a cartridge 12, which has already been described in detail above, to the cuff 16.

[0052] Finally, according to Fig. An adapter 10 with a further syringe 17 is coupled to the closure device 9. This enables the graft 4 to be moved by pushing the plunger of the syringe 17 into the cartridge 12 and then introducing the graft 4 into the body.

[0053] The device according to the invention for storing and transporting a transplant 4 enables the receiving device 3 to be loaded with the transplant 4 and safe storage and / or safe transport in the container 2.

[0054] The following parts are required, for example, to load the receiving device 3: the receiving device 3, a closure device 9 with a grid closure and an adapter area for connecting a hose 15 and / or a syringe 11, this hose 15, wherein the hose 15 has an adapter 10 at each of its two ends, and a syringe 11. The closure device 9 can be designed in the form of a cuff with a grid and a rinsing port. An adapter 10 for the hose 15 or the syringe 11 can be inserted into the rinsing port.

[0055] In principle, both of the above-described methods can be used to introduce graft 4 into the body.

[0056] The following parts are required for variant 1: closure device 8 - cuff with grid closure -, receiving device 3, cuff 16 without grid closure, cartridge 12, hose 15 with adapter 10 and syringe 17.

[0057] For variant 2 the following parts are required: cartridge 12, cuff 16 without grid closure, receiving device 3, closure device 9 with grid closure and adaptation area for inserting an adapter, this adapter and syringe.

[0058] In advantageous embodiments of the device according to the invention, these embodiments can have components according to the variants shown below: Option 1: • 8 cuffs with grid closure • 3 Receiving facility • 9 Cuff with grid closure for adapter 10 and syringe 11 • 16 Cuff without grid closure replaces cuff 9 • 12 cartridges • 15 hoses • 10 adapters • 11 syringes • 17 syringes Option 2: • 8 cuffs with grid closure • 3 Receiving facility • 9 Cuff with grid closure for adapter 10 and syringe 11 • 16 Cuff without grid closure replaces cuff 8 • 12 cartridges • 10 adapters • 17 syringes

[0059] With regard to the handling of the receiving device 3, which is located in the container 2 and thus in the medium 1 and is equipped with a transplant 4, a surgeon, for example, has complete flexibility. He can, for instance, perform the coupling and uncoupling steps of the described components, as previously explained in various embodiments, while the receiving device 3 is located in the container 2 and thus in the medium 1. Alternatively, depending on the requirements, he can also remove the receiving device 3 with the transplant 4 contained therein from the medium 1 and, if necessary, reinsert it into the medium 1 after coupling and / or uncoupling procedures. The surgeon has complete freedom of handling in this respect, depending on the requirements and / or preference.

[0060] Regarding further advantageous embodiments of the device, the receiving device and the set according to the invention, reference is made to the general part of the description and to the attached claims to avoid repetition.

[0061] Finally, it should be expressly pointed out that the exemplary embodiments described above serve only to illustrate the claimed teaching, but do not limit it to these exemplary embodiments. Reference symbol list 1 Medium 2 containers 3. Receiving facility 4 transplants 5 Recording room 6 rounds 7th round 8 Locking device 9 Locking device 10 adapters 11 syringes 12 cartridges 13 Opening 14 Opening 15 hoses 16 cuff 17 syringes 18 syringes

Claims

Device for storing and transporting a graft (4) or implant, comprising a container (2) that can be filled with a medium (1), preferably a nutrient medium, and a receiving device (3) for the graft (4) or implant that can be arranged in the container (2), wherein the receiving device (3) has a receiving chamber (5) for the graft (4) or implant and two passages (6, 7) leading to the receiving chamber (5), at least one of which (6, 7) is dimensioned for inserting and / or removing the graft (4) or implant into or from the receiving chamber (5), and each of which has a closure device (8, 9) for the two passages (6, 7), at least one of which (8, 9) is permeable to the medium (1), characterized in that at least one of the two closure devices (8, 9) has a grid to provide permeability to the medium (1). Device according to claim 1, characterized in that the receiving device (3) is designed as a sleeve or cylinder. Device according to claim 1 or 2, characterized in that the locking devices (8, 9) can be attached to the receiving device (3) and are preferably designed as cuffs. Device according to one of claims 1 to 3, characterized in that the locking devices (8, 9) are made of at least slightly elastic material, preferably plastic. Device according to one of claims 1 to 4, characterized in that the receiving device (3) or at least one of the two closure devices (8, 9) for connecting a cuff or an adapter (10) or with an integrated adapter or adapter area is designed in such a way that it is possible to connect a hose, a syringe (11), preferably a disposable syringe, or a device for supplying and / or draining the medium (1) and / or another fluid medium, preferably a dye solution. Device according to one of claims 1 to 5, characterized in that the receiving device (3) is made of preferably transparent plastic, glass or metal. Receiving device (3) according to one of claims 1 to 6, each with a closing device (8, 9) for the two passages (6, 7) according to one of the preceding claims, of which at least one closing device (8, 9) is permeable to the medium (1) and wherein at least one of the two closing devices (8, 9) has a grid to provide permeability to the medium (1). Receiving device (3) according to claim 7, characterized in that a cartridge (12) or a sleeve with two opposing end openings (13, 14) is coupled to one of the two passages (6, 7), wherein the first opening (13) has a larger diameter than the second opening (14). Receiving device (3) according to claim 8, characterized in that the outer edge of the second opening (14) can be inserted into the nozzle of a syringe (11) and / or that the first opening (13) can be attached to the nozzle of the same or of a syringe (11). Set comprising a device according to any one of claims 1 to 6 in a sterilized state or in packaging suitable for sterilization. Set according to claim 10, characterized in that the set additionally comprises a syringe (11) and an adapter (10) and / or hose suitable for connection to the device and / or that the receiving device (3) already contains a graft (4) or implant.

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